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The map label for this gene is sufS [C]

Identifier: 116695456

GI number: 116695456

Start: 1701537

End: 1702805

Strand: Direct

Name: sufS [C]

Synonym: H16_B1515

Alternate gene names: 116695456

Gene position: 1701537-1702805 (Clockwise)

Preceding gene: 116695455

Following gene: 116695457

Centisome position: 58.42

GC content: 67.3

Gene sequence:

>1269_bases
ATGAACACGGCTGCGCATGAACGGATGGCCGTGGAGCACGCGGTGCCGGCCGCCAGCCTGGAGGTGGAGCGGCTGCGGAA
GGATTTCCCGATCCTGCGCCAGACCATCAACGGCAGGCCGCTGGTCTATCTGGACAACGCCGCCACCACCCAGAAGCCGC
AAAGCGTGATCGATTGCGAAGCGCATTACTACGCCGCGCTCAACGCCAATATCCACCGCGGCGTGCATACCCTGAGCCAG
CGCGCCACCGATGCCTACGAGGCCGCGCGCGACGCAGTGCGAGACCTGATCAACGCCGCCGGGCGCGAGGAAATCGTGTT
CGTGCGCGGCACCACCGAGGCCATCAACCTGGTGGCGGCAAGCTTCGGCCAGCGCCTGCGCCCGGGCGACGAGGTCCTGA
TCAGCGCGATGGAGCACCACTCCAATATCGTGCCGTGGCAACTGGCGTGCCAGCGCACCGGCGCCTTGCTGCAGGTGGCG
CCGATCAACGATGCCGGCGAGCTGATGCTGGAGCAGTTCGCGCGATTGCTCGGCCCGCGCACCAGACTGGTCGCGCTGAC
GCACCTCTCCAACGCGCTTGGCACCGTCAACCCGGTGCGGCACATCATCGAGCTGGCGCATGACCATGGCATCCCGGTGC
TGATCGATGGCGCCCAGGCCGTGCCGCACCTAAAGGTCGACGTGCAGGCCCTCGATTGCGATTTCTACGCGTTCTCCGGG
CACAAGCTTTACGGGCCCACCGGCGTCGGCGTGCTCTACGGCAAGGCCGCGCTGCTCGATGCCATGCCGCCTTACCAGGG
CGGCGGGGACATGATTCGCGAGGTCACGTTCCGCAAGACCACATACAACGAGCTGCCCTACAAGTTCGAGGCGGGCACCC
CCAATATCGCCGGCGTCATCGCCCTTGGCGCCGCCATCGGGTACGTGCGCGCGCTCGGCCTGGAAGCCATCGCCGCCCAC
GAGCACGCGCTGCTCGCTTACGCCAGCGCGCAGGCAGCAAGGATCGCCGGCCTGCGCATGATCGGCACGGCTGCCGACAG
GGCGAGCATCCTCTCGTTCACGCTGGACGGCATCCATCCCCACGATGTCGGCACCATCCTCGATCAGCACGGCGTCGCGG
TCCGTGCCGGCCACCATTGCGCCATGCCGGTGATGGAGCGCTTCGGCGTGCCCGCCACGGTGCGCGCTTCCTTCGCGCTG
TACAACACGCGTGAAGAGGTGGATGCACTGTTTGCTGCCGTGCGCGCGGCACAGGAGGTATTCGCCTGA

Upstream 100 bases:

>100_bases
TCGCCGAAGAGGTCGTCAGGCGGCTCGGCCCTGCCCCATTGCGCACGCGGCTGGAAACGCTCTTGCGCGGCAAGCTGCCG
GAGCCTGTGAAGGAGCTGCC

Downstream 100 bases:

>100_bases
TGTCTGACCTGCGCAGCCTCTACCAGGAAGTGGTTGTCGACCACAGCCGCTCGCCGCGCAATTTCGGGCGGCTGGCGGCA
GCGAACCGCAGCGCCGAGGG

Product: cysteine desulfurase (SufS)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MNTAAHERMAVEHAVPAASLEVERLRKDFPILRQTINGRPLVYLDNAATTQKPQSVIDCEAHYYAALNANIHRGVHTLSQ
RATDAYEAARDAVRDLINAAGREEIVFVRGTTEAINLVAASFGQRLRPGDEVLISAMEHHSNIVPWQLACQRTGALLQVA
PINDAGELMLEQFARLLGPRTRLVALTHLSNALGTVNPVRHIIELAHDHGIPVLIDGAQAVPHLKVDVQALDCDFYAFSG
HKLYGPTGVGVLYGKAALLDAMPPYQGGGDMIREVTFRKTTYNELPYKFEAGTPNIAGVIALGAAIGYVRALGLEAIAAH
EHALLAYASAQAARIAGLRMIGTAADRASILSFTLDGIHPHDVGTILDQHGVAVRAGHHCAMPVMERFGVPATVRASFAL
YNTREEVDALFAAVRAAQEVFA

Sequences:

>Translated_422_residues
MNTAAHERMAVEHAVPAASLEVERLRKDFPILRQTINGRPLVYLDNAATTQKPQSVIDCEAHYYAALNANIHRGVHTLSQ
RATDAYEAARDAVRDLINAAGREEIVFVRGTTEAINLVAASFGQRLRPGDEVLISAMEHHSNIVPWQLACQRTGALLQVA
PINDAGELMLEQFARLLGPRTRLVALTHLSNALGTVNPVRHIIELAHDHGIPVLIDGAQAVPHLKVDVQALDCDFYAFSG
HKLYGPTGVGVLYGKAALLDAMPPYQGGGDMIREVTFRKTTYNELPYKFEAGTPNIAGVIALGAAIGYVRALGLEAIAAH
EHALLAYASAQAARIAGLRMIGTAADRASILSFTLDGIHPHDVGTILDQHGVAVRAGHHCAMPVMERFGVPATVRASFAL
YNTREEVDALFAAVRAAQEVFA
>Mature_422_residues
MNTAAHERMAVEHAVPAASLEVERLRKDFPILRQTINGRPLVYLDNAATTQKPQSVIDCEAHYYAALNANIHRGVHTLSQ
RATDAYEAARDAVRDLINAAGREEIVFVRGTTEAINLVAASFGQRLRPGDEVLISAMEHHSNIVPWQLACQRTGALLQVA
PINDAGELMLEQFARLLGPRTRLVALTHLSNALGTVNPVRHIIELAHDHGIPVLIDGAQAVPHLKVDVQALDCDFYAFSG
HKLYGPTGVGVLYGKAALLDAMPPYQGGGDMIREVTFRKTTYNELPYKFEAGTPNIAGVIALGAAIGYVRALGLEAIAAH
EHALLAYASAQAARIAGLRMIGTAADRASILSFTLDGIHPHDVGTILDQHGVAVRAGHHCAMPVMERFGVPATVRASFAL
YNTREEVDALFAAVRAAQEVFA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=215, Percent_Identity=30.2325581395349, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI156713448, Length=427, Percent_Identity=26.6978922716628, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1787970, Length=398, Percent_Identity=54.5226130653266, Blast_Score=445, Evalue=1e-126,
Organism=Escherichia coli, GI1789175, Length=399, Percent_Identity=43.859649122807, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI48994898, Length=217, Percent_Identity=31.3364055299539, Blast_Score=95, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI25143064, Length=213, Percent_Identity=29.5774647887324, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI193211090, Length=376, Percent_Identity=23.4042553191489, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319831, Length=235, Percent_Identity=28.5106382978723, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI20129463, Length=278, Percent_Identity=32.0143884892086, Blast_Score=115, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45477; Mature: 45477

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTAAHERMAVEHAVPAASLEVERLRKDFPILRQTINGRPLVYLDNAATTQKPQSVIDCE
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHCCCC
AHYYAALNANIHRGVHTLSQRATDAYEAARDAVRDLINAAGREEIVFVRGTTEAINLVAA
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHH
SFGQRLRPGDEVLISAMEHHSNIVPWQLACQRTGALLQVAPINDAGELMLEQFARLLGPR
HHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCC
TRLVALTHLSNALGTVNPVRHIIELAHDHGIPVLIDGAQAVPHLKVDVQALDCDFYAFSG
HHEEEHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEEEEEEEECC
HKLYGPTGVGVLYGKAALLDAMPPYQGGGDMIREVTFRKTTYNELPYKFEAGTPNIAGVI
CEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHH
ALGAAIGYVRALGLEAIAAHEHALLAYASAQAARIAGLRMIGTAADRASILSFTLDGIHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHEEEEEECCCCC
HDVGTILDQHGVAVRAGHHCAMPVMERFGVPATVRASFALYNTREEVDALFAAVRAAQEV
CHHHHHHHCCCCEEECCCCCHHHHHHHCCCCEEHEEHEEECCCHHHHHHHHHHHHHHHHH
FA
CC
>Mature Secondary Structure
MNTAAHERMAVEHAVPAASLEVERLRKDFPILRQTINGRPLVYLDNAATTQKPQSVIDCE
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHCCCC
AHYYAALNANIHRGVHTLSQRATDAYEAARDAVRDLINAAGREEIVFVRGTTEAINLVAA
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHH
SFGQRLRPGDEVLISAMEHHSNIVPWQLACQRTGALLQVAPINDAGELMLEQFARLLGPR
HHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCC
TRLVALTHLSNALGTVNPVRHIIELAHDHGIPVLIDGAQAVPHLKVDVQALDCDFYAFSG
HHEEEHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEEEEEEEEECC
HKLYGPTGVGVLYGKAALLDAMPPYQGGGDMIREVTFRKTTYNELPYKFEAGTPNIAGVI
CEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHH
ALGAAIGYVRALGLEAIAAHEHALLAYASAQAARIAGLRMIGTAADRASILSFTLDGIHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHEEEEEECCCCC
HDVGTILDQHGVAVRAGHHCAMPVMERFGVPATVRASFALYNTREEVDALFAAVRAAQEV
CHHHHHHHCCCCEEECCCCCHHHHHHHCCCCEEHEEHEEECCCHHHHHHHHHHHHHHHHH
FA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA