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The map label for this gene is sufC [H]

Identifier: 116695454

GI number: 116695454

Start: 1699466

End: 1700212

Strand: Direct

Name: sufC [H]

Synonym: H16_B1513

Alternate gene names: 116695454

Gene position: 1699466-1700212 (Clockwise)

Preceding gene: 116695453

Following gene: 116695455

Centisome position: 58.35

GC content: 64.79

Gene sequence:

>747_bases
ATGCTTGAGATTCGCAAGCTGCACGTCAGCGTAGACGACAAGCCCATCCTGCACGGCATCGACCTCAGCGTGAAGGCCGG
CGAGGTGCACGCCATCATGGGCCCGAACGGTTCGGGCAAGAGCACCCTGGCCCACGTACTGGCCGGGCGCGACCGCTTTA
CCGTGACAGAGGGCGAAGTCCTCTATGACGGCACCAGCCTGCTTGGCATGCCGCCGGAAGAGCGCGCCCGCGCGGGCATC
TTCCTCGCCTTCCAGTATCCGGTGGAAATCCCCGGCGTCTCCAATATCTACCTGCTCAAGGCGGGGCTCAACGCGATCCG
CAAGCACCGTGGCGAGCCGGAGCTGGACGCCATGGATTTCCTCGCCCTGGTCAAGGACAAACTCCAGCTCATGGAGATGG
ACCAGGACCTGCTTTACCGATCGGTGAACGAGGGCTTCTCCGGCGGGGAGAAGAAGCGCAACGAGATCCTGCAGATGGCA
GTGCTGGAGCCGCGGCTCGCCATTCTCGACGAGACCGACTCCGGCCTCGACATCGATGCACTCAAGATCGTCGCCAGGGG
CATCGAGGCCATGCGCAGCCCGCAACGCGCGATTGTGCTGGTCACGCACTACCAGCGCCTGCTCGACTACATCGTGCCGG
ACCAGGTCCACGTGCTTGCGCAAGGCCGCATCGCCAGGTCCGGCGGGCCGGAGCTGGCGCGCGAACTGGAGCGGCACGGC
TATGCCGCGATGGAGTCTTCGACATGA

Upstream 100 bases:

>100_bases
CAAGGAAGTATTCAAGGAGCTGCCGATGGAATTCGCGGTGGAAGCCCAGAAGCTGCTGGGCGTGAGCCTGGAAGGCAGTA
TCGGATGAAAGAAGCCAGCC

Downstream 100 bases:

>100_bases
GCGCAAGCGGACTGGAGCACTATCTCGCCGAGTTCGCCCGCGTCGAGGCCGCACTGCCCGGCCGCCGTCTGGGCTGGCTT
GCGCACGCGCGGCGGCAGGC

Product: iron sulfur cluster assembly protein SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MLEIRKLHVSVDDKPILHGIDLSVKAGEVHAIMGPNGSGKSTLAHVLAGRDRFTVTEGEVLYDGTSLLGMPPEERARAGI
FLAFQYPVEIPGVSNIYLLKAGLNAIRKHRGEPELDAMDFLALVKDKLQLMEMDQDLLYRSVNEGFSGGEKKRNEILQMA
VLEPRLAILDETDSGLDIDALKIVARGIEAMRSPQRAIVLVTHYQRLLDYIVPDQVHVLAQGRIARSGGPELARELERHG
YAAMESST

Sequences:

>Translated_248_residues
MLEIRKLHVSVDDKPILHGIDLSVKAGEVHAIMGPNGSGKSTLAHVLAGRDRFTVTEGEVLYDGTSLLGMPPEERARAGI
FLAFQYPVEIPGVSNIYLLKAGLNAIRKHRGEPELDAMDFLALVKDKLQLMEMDQDLLYRSVNEGFSGGEKKRNEILQMA
VLEPRLAILDETDSGLDIDALKIVARGIEAMRSPQRAIVLVTHYQRLLDYIVPDQVHVLAQGRIARSGGPELARELERHG
YAAMESST
>Mature_248_residues
MLEIRKLHVSVDDKPILHGIDLSVKAGEVHAIMGPNGSGKSTLAHVLAGRDRFTVTEGEVLYDGTSLLGMPPEERARAGI
FLAFQYPVEIPGVSNIYLLKAGLNAIRKHRGEPELDAMDFLALVKDKLQLMEMDQDLLYRSVNEGFSGGEKKRNEILQMA
VLEPRLAILDETDSGLDIDALKIVARGIEAMRSPQRAIVLVTHYQRLLDYIVPDQVHVLAQGRIARSGGPELARELERHG
YAAMESST

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787972, Length=244, Percent_Identity=61.8852459016393, Blast_Score=313, Evalue=7e-87,
Organism=Escherichia coli, GI1787370, Length=241, Percent_Identity=27.8008298755187, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788225, Length=233, Percent_Identity=28.3261802575107, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788761, Length=231, Percent_Identity=26.4069264069264, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787029, Length=234, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789864, Length=234, Percent_Identity=25.6410256410256, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790467, Length=227, Percent_Identity=32.5991189427313, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1786698, Length=204, Percent_Identity=27.9411764705882, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081791, Length=246, Percent_Identity=26.4227642276423, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787500, Length=216, Percent_Identity=28.7037037037037, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87081709, Length=231, Percent_Identity=23.8095238095238, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788506, Length=223, Percent_Identity=27.3542600896861, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081834, Length=192, Percent_Identity=30.2083333333333, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787792, Length=228, Percent_Identity=25.8771929824561, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI87082267, Length=177, Percent_Identity=31.638418079096, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI1786654, Length=221, Percent_Identity=27.6018099547511, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI1789891, Length=218, Percent_Identity=27.0642201834862, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=220, Percent_Identity=30, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71996809, Length=222, Percent_Identity=28.8288288288288, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193209708, Length=237, Percent_Identity=29.1139240506329, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17565938, Length=219, Percent_Identity=26.9406392694064, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25146777, Length=243, Percent_Identity=26.7489711934156, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17543740, Length=215, Percent_Identity=26.9767441860465, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19920532, Length=217, Percent_Identity=29.9539170506912, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24580930, Length=217, Percent_Identity=29.9539170506912, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574533, Length=239, Percent_Identity=28.0334728033473, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27358; Mature: 27358

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEIRKLHVSVDDKPILHGIDLSVKAGEVHAIMGPNGSGKSTLAHVLAGRDRFTVTEGEV
CCEEEEEEEECCCCCEEEECCEEEECCCEEEEECCCCCCHHHHHHHHCCCCCEEEECCCE
LYDGTSLLGMPPEERARAGIFLAFQYPVEIPGVSNIYLLKAGLNAIRKHRGEPELDAMDF
EECCCCCCCCCCHHHHCCCEEEEEECCEECCCCCCEEEEHHHHHHHHHCCCCCCHHHHHH
LALVKDKLQLMEMDQDLLYRSVNEGFSGGEKKRNEILQMAVLEPRLAILDETDSGLDIDA
HHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHH
LKIVARGIEAMRSPQRAIVLVTHYQRLLDYIVPDQVHVLAQGRIARSGGPELARELERHG
HHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCC
YAAMESST
CCCCCCCC
>Mature Secondary Structure
MLEIRKLHVSVDDKPILHGIDLSVKAGEVHAIMGPNGSGKSTLAHVLAGRDRFTVTEGEV
CCEEEEEEEECCCCCEEEECCEEEECCCEEEEECCCCCCHHHHHHHHCCCCCEEEECCCE
LYDGTSLLGMPPEERARAGIFLAFQYPVEIPGVSNIYLLKAGLNAIRKHRGEPELDAMDF
EECCCCCCCCCCHHHHCCCEEEEEECCEECCCCCCEEEEHHHHHHHHHCCCCCCHHHHHH
LALVKDKLQLMEMDQDLLYRSVNEGFSGGEKKRNEILQMAVLEPRLAILDETDSGLDIDA
HHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHH
LKIVARGIEAMRSPQRAIVLVTHYQRLLDYIVPDQVHVLAQGRIARSGGPELARELERHG
HHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCC
YAAMESST
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]