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The map label for this gene is ccmB2 [H]

Identifier: 116694898

GI number: 116694898

Start: 1075253

End: 1075924

Strand: Direct

Name: ccmB2 [H]

Synonym: H16_B0953

Alternate gene names: 116694898

Gene position: 1075253-1075924 (Clockwise)

Preceding gene: 116694897

Following gene: 116694899

Centisome position: 36.92

GC content: 67.86

Gene sequence:

>672_bases
ATGCTGGATCCGGTCCTGAAACTGATCGCGCGTGAGCTGCTGCTGGCGTGGCGTCGCCCGTCGGCGGTGCTGACACCGCT
CGCCTTTTTTGTCGCGGTGGTCAGCCTGTTTCCGCTGGCGGTTGGCCCGGAGCGGATGTTTCTCGCCAGGCTGGCGCCCG
GTGTGATCTGGGTCGCCGCCTTGCTGGCGACGCTGCTGGGCATGGAGCGTTTGTTCGAATCCGATTTCCGCGACGGCAGC
CTGGAAGTTATCGCGCTCGCGCCGCAGTCCCTGACCTTGATGGTGCTCGGCAAGGTGACCGGCTTCTGGCTCGGGGCGGG
CCTGCCGCTGGTGTTGCTGACGCCACTGCTTGGCGTTCAGCTCGGCGTGCCTGACGGCGAGCTGGCACAACTGGCACTGT
CGCTGCTGCTCGGTACGCCGACGCTGTGCCTGATCGCGGCAATCGCTGCCGCGCTGACGCTGTCGCTGCAGCGCGGCGGC
CCGCTGCTGGCATTGCTGGTGCTGCCACTGGCAGCGCCGGTACTGGTGTTCGGCTGCGGCGTCGCCGCCGCCAGCACTGC
GGCGGAATTGCAGGCGAATCTTTCGCTGCTGGGGGCATGCCTGCTGACTGCCGTTGCGTCGGCGCCATGGGCCACCGCCG
CGGCGCTCAGGATTGGATTGGAGTCTGTCTGA

Upstream 100 bases:

>100_bases
TGCTGGTGTTTGCGAACCACTACCCGCTGCGGCTGGTGGCCGCGCGGATGCGCGAGCTTGCCATCCCGGCGATCGCCGAT
CGATCGCAGCAGGAGGCGGC

Downstream 100 bases:

>100_bases
TGGCCACCTTGAATATCTGGAAGTACGCCGCGCCCCAAGCCTTCTATCCGCTCGCCGGGCATCTGGTGCCATGGTTTGGC
GCTGCTGCCGCAGTGTCTGG

Product: ABC transporter permease

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MLDPVLKLIARELLLAWRRPSAVLTPLAFFVAVVSLFPLAVGPERMFLARLAPGVIWVAALLATLLGMERLFESDFRDGS
LEVIALAPQSLTLMVLGKVTGFWLGAGLPLVLLTPLLGVQLGVPDGELAQLALSLLLGTPTLCLIAAIAAALTLSLQRGG
PLLALLVLPLAAPVLVFGCGVAAASTAAELQANLSLLGACLLTAVASAPWATAAALRIGLESV

Sequences:

>Translated_223_residues
MLDPVLKLIARELLLAWRRPSAVLTPLAFFVAVVSLFPLAVGPERMFLARLAPGVIWVAALLATLLGMERLFESDFRDGS
LEVIALAPQSLTLMVLGKVTGFWLGAGLPLVLLTPLLGVQLGVPDGELAQLALSLLLGTPTLCLIAAIAAALTLSLQRGG
PLLALLVLPLAAPVLVFGCGVAAASTAAELQANLSLLGACLLTAVASAPWATAAALRIGLESV
>Mature_223_residues
MLDPVLKLIARELLLAWRRPSAVLTPLAFFVAVVSLFPLAVGPERMFLARLAPGVIWVAALLATLLGMERLFESDFRDGS
LEVIALAPQSLTLMVLGKVTGFWLGAGLPLVLLTPLLGVQLGVPDGELAQLALSLLLGTPTLCLIAAIAAALTLSLQRGG
PLLALLVLPLAAPVLVFGCGVAAASTAAELQANLSLLGACLLTAVASAPWATAAALRIGLESV

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=216, Percent_Identity=47.6851851851852, Blast_Score=136, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22938; Mature: 22938

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDPVLKLIARELLLAWRRPSAVLTPLAFFVAVVSLFPLAVGPERMFLARLAPGVIWVAA
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LLATLLGMERLFESDFRDGSLEVIALAPQSLTLMVLGKVTGFWLGAGLPLVLLTPLLGVQ
HHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
LGVPDGELAQLALSLLLGTPTLCLIAAIAAALTLSLQRGGPLLALLVLPLAAPVLVFGCG
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
VAAASTAAELQANLSLLGACLLTAVASAPWATAAALRIGLESV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDPVLKLIARELLLAWRRPSAVLTPLAFFVAVVSLFPLAVGPERMFLARLAPGVIWVAA
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LLATLLGMERLFESDFRDGSLEVIALAPQSLTLMVLGKVTGFWLGAGLPLVLLTPLLGVQ
HHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
LGVPDGELAQLALSLLLGTPTLCLIAAIAAALTLSLQRGGPLLALLVLPLAAPVLVFGCG
CCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
VAAASTAAELQANLSLLGACLLTAVASAPWATAAALRIGLESV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]