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The map label for this gene is ycgM [C]

Identifier: 116694820

GI number: 116694820

Start: 991523

End: 992221

Strand: Direct

Name: ycgM [C]

Synonym: H16_B0874

Alternate gene names: 116694820

Gene position: 991523-992221 (Clockwise)

Preceding gene: 116694819

Following gene: 116694821

Centisome position: 34.04

GC content: 67.24

Gene sequence:

>699_bases
ATGTCCTACGTCTTCACGCCCCCCGCCACCGTTTCCATCCCCGTTGCCGGCAGCGACGACCAGTTCGCCGTGCGCCGCGT
CTATTGCGTGGGCCGCAACTACGCCGCCCATGCGCGCGAGATGGGCTTCGATCCCGACCGCGAGCCGCCGTTCTTCTTCT
GCAAGCCGGCGGACGCGATCGTCCCGGTGCAGGCAGGTACCACGCTGGACCTGCCGTATCCGGCGCAGACGCAGAACTAC
CACTACGAGGCCGAGCTGGTGGCCGTGATCGGCAAGGCTGGTTCGGATATCCCGGTCGAACAGGCACTCGAACACGTCTG
GGGCTATGCCGTCGGCCTCGACATGACCCGCCGCGACCTGCAGATGAAGATGCGCGAAATGGGCCGCCCCTGGGAAATCG
GCAAGGCCTTCGATGCCTCGGCGCCGGTCGCCCCGATCCACCGCGCCAGCGAGATCGGGCATCCGCAGCAGGCCGGCATC
TGGCTGACCGTCAACGGTGACACGAAGCAGCGCAGCGACGTGTCGCACCTGATCTGGTCGGTAGCAGAGACGGTGGCCTA
CCTGTCGCAGTTCTTCCGCCTGGAACCGGGCGATGTGATCTTTACCGGCACACCGGAAGGCGTGGGCGCGGTCAAGGCCG
GCGAGACCATGGTCACGGGCGTGGACGGCCTCGGCGAACTGGCCGTGCGCGTGGTCTGA

Upstream 100 bases:

>100_bases
CCTGAGCGTCTCGCGACCCTGATCCGACCTGCCCCGGGCGGTGCCTGCGCGCACCGCCTGAGGCTCCCGCTTACCTGACG
ACTTCCGGAAACCTCGAACC

Downstream 100 bases:

>100_bases
ACCTCTGAATCGCAGCACAGGCATTACCGATCATGCAGCTCTATAGTTTCTTCAACAGCTCCACGTCCTACCGGGTGCGC
ATCGCGCTGGCCCTCAAGGG

Product: fumarylpyruvate hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSYVFTPPATVSIPVAGSDDQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAIVPVQAGTTLDLPYPAQTQNY
HYEAELVAVIGKAGSDIPVEQALEHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDASAPVAPIHRASEIGHPQQAGI
WLTVNGDTKQRSDVSHLIWSVAETVAYLSQFFRLEPGDVIFTGTPEGVGAVKAGETMVTGVDGLGELAVRVV

Sequences:

>Translated_232_residues
MSYVFTPPATVSIPVAGSDDQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAIVPVQAGTTLDLPYPAQTQNY
HYEAELVAVIGKAGSDIPVEQALEHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDASAPVAPIHRASEIGHPQQAGI
WLTVNGDTKQRSDVSHLIWSVAETVAYLSQFFRLEPGDVIFTGTPEGVGAVKAGETMVTGVDGLGELAVRVV
>Mature_231_residues
SYVFTPPATVSIPVAGSDDQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAIVPVQAGTTLDLPYPAQTQNYH
YEAELVAVIGKAGSDIPVEQALEHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDASAPVAPIHRASEIGHPQQAGIW
LTVNGDTKQRSDVSHLIWSVAETVAYLSQFFRLEPGDVIFTGTPEGVGAVKAGETMVTGVDGLGELAVRVV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=207, Percent_Identity=39.6135265700483, Blast_Score=160, Evalue=9e-40,
Organism=Homo sapiens, GI66348062, Length=200, Percent_Identity=40.5, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI215422413, Length=204, Percent_Identity=39.7058823529412, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI156231349, Length=215, Percent_Identity=34.8837209302326, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI40786394, Length=215, Percent_Identity=34.4186046511628, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1787428, Length=212, Percent_Identity=38.2075471698113, Blast_Score=150, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17557057, Length=200, Percent_Identity=35.5, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324161, Length=221, Percent_Identity=28.9592760180996, Blast_Score=115, Evalue=6e-27,
Organism=Drosophila melanogaster, GI28571789, Length=209, Percent_Identity=34.4497607655502, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28572127, Length=216, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24663695, Length=221, Percent_Identity=27.1493212669683, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 25279; Mature: 25148

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYVFTPPATVSIPVAGSDDQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAI
CCEEECCCCEEEEEECCCCCCCEEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCCE
VPVQAGTTLDLPYPAQTQNYHYEAELVAVIGKAGSDIPVEQALEHVWGYAVGLDMTRRDL
EEECCCCEECCCCCCCCCCEEEHEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHH
QMKMREMGRPWEIGKAFDASAPVAPIHRASEIGHPQQAGIWLTVNGDTKQRSDVSHLIWS
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHH
VAETVAYLSQFFRLEPGDVIFTGTPEGVGAVKAGETMVTGVDGLGELAVRVV
HHHHHHHHHHHHCCCCCCEEEECCCCCCCCEECCCEEEECCCCCCCEEEECC
>Mature Secondary Structure 
SYVFTPPATVSIPVAGSDDQFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAI
CEEECCCCEEEEEECCCCCCCEEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCCE
VPVQAGTTLDLPYPAQTQNYHYEAELVAVIGKAGSDIPVEQALEHVWGYAVGLDMTRRDL
EEECCCCEECCCCCCCCCCEEEHEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHH
QMKMREMGRPWEIGKAFDASAPVAPIHRASEIGHPQQAGIWLTVNGDTKQRSDVSHLIWS
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHH
VAETVAYLSQFFRLEPGDVIFTGTPEGVGAVKAGETMVTGVDGLGELAVRVV
HHHHHHHHHHHHCCCCCCEEEECCCCCCCCEECCCEEEECCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]