Click here to switch to the map view.

The map label for this gene is 116694819

Identifier: 116694819

GI number: 116694819

Start: 990381

End: 991427

Strand: Direct

Name: 116694819

Synonym: H16_B0873

Alternate gene names: NA

Gene position: 990381-991427 (Clockwise)

Preceding gene: 116694817

Following gene: 116694820

Centisome position: 34.0

GC content: 68.29

Gene sequence:

>1047_bases
ATGTCCGAACACACCCCAGACCCGGCCCGCGTGGCCTATTACGAAGAAATCGGCCGCAGCCACATGACCCCGCTGTGGGA
GTCGCTGCACGCGCTGGTGCCGCCGCAACCGCGGCCGCAGATCGTTCCCGCCATCTGGAAGTACGCCCAGATCCGCCCGC
TGGTGATGCAGGCCGGCGGCGTCATCAGCGCCGAGGAAGCGGTGCGCCGCGTGCTGGTGCTGGAGAACCCGGGCATTCCC
GGCAAGTCGAGCATCACCTCCACGCTGTACGCCGGCCTGCAGCTGATCCTGCCGGGCGAAATTGCGCCCAGCCACCGCCA
TACCCAGTCCGCGCTGCGCTTTATCGTGGAAGGCAAGGGCGCCTGGACCGCGGTCAACGGCGAGCGCACCACCATGCATC
CCGGCGACTTCATCATCACGCCGTCGTGGACCTGGCATGACCATGGCAACCCCGCCGTCGAGGACGGCGGCGAGCCGGTG
GTGTGGCTGGACGGGCTGGATATTCCGCTGGTGCAGCAGTTCGATGCCGGGTTTGCCGAGAACTACCCGCAAGCCCAGCA
GCCCGTGACCCGCGTCGAGGGCGACAGCTTTGCCCGCTTCGGCCATAACATGGTGCCGGTGCGGCACCGCGTGACCGATC
CCACTTCGCCGGTCTTCAGCTACCCGTACGAGCGCTCGCGCGAGGCGCTGGACCAGCTCTACCGCAACGGCGAGCTCGAT
GCCTGGGACGGCGTCAAGCTGCGCTATATCAACCCGGCCACCGGCGGCTGGCCGATGCCGACCATCGCCACCTTCATGCA
GTACCTGCCGGCGGGCTTCCAGGGAAAGACCTACCGCAGCACCGACGCCACCGTCTACAGCGTGGTGGAAGGGCGCGGCA
CGGTGCGCATCGGCGACGACCAGTTCCAGTTCGAGCCGCGCGACACCTTCGTGGCCCCGTCGTGGGCGCCGGTGCAGCTG
GGCGCGCTGGAAGACGCGGTGCTGTTCAGCTATTCCGACCGGCCCGTGCTGTCCGCGATGAACCTGCTGCGCGAAGCGCG
CACCTGA

Upstream 100 bases:

>100_bases
TTATAGGGCCGGGCGTATAACGACAACAAGACGGTGCGCATCGACACAGGCACCCGCAAAGAGCGCTCCCCAAAGCACCT
GCAAAAGTCACGGAGACAGC

Downstream 100 bases:

>100_bases
GCGTCTCGCGACCCTGATCCGACCTGCCCCGGGCGGTGCCTGCGCGCACCGCCTGAGGCTCCCGCTTACCTGACGACTTC
CGGAAACCTCGAACCATGTC

Product: gentisate 1,2-dioxygenase

Products: maleylpyruvate

Alternate protein names: Cupin 2 Domain-Containing Protein; Cupin 2 Conserved Barrel Domain Protein; Cupin 2 Barrel; Cupin 2 Conserved Barrel Domain-Containing Protein; 1 2-Dioxygenase; Gentisate 1 2-Dioxygenase Oxidoreductase Protein; Cupin 2 Protein; 1-Hydroxy-2-Naphthoate Dioxygenase; Gentisate 1 2-Dioxygenase Oxidoreductase; Dioxygenase Oxidoreductase Protein; Dioxygenase

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSEHTPDPARVAYYEEIGRSHMTPLWESLHALVPPQPRPQIVPAIWKYAQIRPLVMQAGGVISAEEAVRRVLVLENPGIP
GKSSITSTLYAGLQLILPGEIAPSHRHTQSALRFIVEGKGAWTAVNGERTTMHPGDFIITPSWTWHDHGNPAVEDGGEPV
VWLDGLDIPLVQQFDAGFAENYPQAQQPVTRVEGDSFARFGHNMVPVRHRVTDPTSPVFSYPYERSREALDQLYRNGELD
AWDGVKLRYINPATGGWPMPTIATFMQYLPAGFQGKTYRSTDATVYSVVEGRGTVRIGDDQFQFEPRDTFVAPSWAPVQL
GALEDAVLFSYSDRPVLSAMNLLREART

Sequences:

>Translated_348_residues
MSEHTPDPARVAYYEEIGRSHMTPLWESLHALVPPQPRPQIVPAIWKYAQIRPLVMQAGGVISAEEAVRRVLVLENPGIP
GKSSITSTLYAGLQLILPGEIAPSHRHTQSALRFIVEGKGAWTAVNGERTTMHPGDFIITPSWTWHDHGNPAVEDGGEPV
VWLDGLDIPLVQQFDAGFAENYPQAQQPVTRVEGDSFARFGHNMVPVRHRVTDPTSPVFSYPYERSREALDQLYRNGELD
AWDGVKLRYINPATGGWPMPTIATFMQYLPAGFQGKTYRSTDATVYSVVEGRGTVRIGDDQFQFEPRDTFVAPSWAPVQL
GALEDAVLFSYSDRPVLSAMNLLREART
>Mature_347_residues
SEHTPDPARVAYYEEIGRSHMTPLWESLHALVPPQPRPQIVPAIWKYAQIRPLVMQAGGVISAEEAVRRVLVLENPGIPG
KSSITSTLYAGLQLILPGEIAPSHRHTQSALRFIVEGKGAWTAVNGERTTMHPGDFIITPSWTWHDHGNPAVEDGGEPVV
WLDGLDIPLVQQFDAGFAENYPQAQQPVTRVEGDSFARFGHNMVPVRHRVTDPTSPVFSYPYERSREALDQLYRNGELDA
WDGVKLRYINPATGGWPMPTIATFMQYLPAGFQGKTYRSTDATVYSVVEGRGTVRIGDDQFQFEPRDTFVAPSWAPVQLG
ALEDAVLFSYSDRPVLSAMNLLREART

Specific function: Unknown

COG id: COG3435

COG function: function code Q; Gentisate 1,2-dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.13.11.4

Molecular weight: Translated: 38731; Mature: 38600

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHTPDPARVAYYEEIGRSHMTPLWESLHALVPPQPRPQIVPAIWKYAQIRPLVMQAGG
CCCCCCCHHHHHHHHHHCHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHCCC
VISAEEAVRRVLVLENPGIPGKSSITSTLYAGLQLILPGEIAPSHRHTQSALRFIVEGKG
CEEHHHHHHEEEEEECCCCCCCHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHEECCC
AWTAVNGERTTMHPGDFIITPSWTWHDHGNPAVEDGGEPVVWLDGLDIPLVQQFDAGFAE
CEEEECCCCEEECCCCEEECCCEEECCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCHHH
NYPQAQQPVTRVEGDSFARFGHNMVPVRHRVTDPTSPVFSYPYERSREALDQLYRNGELD
CCCCHHCCHHHCCCCHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
AWDGVKLRYINPATGGWPMPTIATFMQYLPAGFQGKTYRSTDATVYSVVEGRGTVRIGDD
CCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCEECCCCCEEEEEECCCCEEEECCC
QFQFEPRDTFVAPSWAPVQLGALEDAVLFSYSDRPVLSAMNLLREART
CEEECCCCCEECCCCCCEEECCCCCEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEHTPDPARVAYYEEIGRSHMTPLWESLHALVPPQPRPQIVPAIWKYAQIRPLVMQAGG
CCCCCCHHHHHHHHHHCHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHCCC
VISAEEAVRRVLVLENPGIPGKSSITSTLYAGLQLILPGEIAPSHRHTQSALRFIVEGKG
CEEHHHHHHEEEEEECCCCCCCHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHEECCC
AWTAVNGERTTMHPGDFIITPSWTWHDHGNPAVEDGGEPVVWLDGLDIPLVQQFDAGFAE
CEEEECCCCEEECCCCEEECCCEEECCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCHHH
NYPQAQQPVTRVEGDSFARFGHNMVPVRHRVTDPTSPVFSYPYERSREALDQLYRNGELD
CCCCHHCCHHHCCCCHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
AWDGVKLRYINPATGGWPMPTIATFMQYLPAGFQGKTYRSTDATVYSVVEGRGTVRIGDD
CCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCEECCCCCEEEEEECCCCEEEECCC
QFQFEPRDTFVAPSWAPVQLGALEDAVLFSYSDRPVLSAMNLLREART
CEEECCCCCEECCCCCCEEECCCCCEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2,5-dihydroxybenzoate; O2

Specific reaction: 2,5-dihydroxybenzoate + O2 = maleylpyruvate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA