Click here to switch to the map view.

The map label for this gene is maiA [H]

Identifier: 116694821

GI number: 116694821

Start: 992254

End: 992895

Strand: Direct

Name: maiA [H]

Synonym: H16_B0875

Alternate gene names: 116694821

Gene position: 992254-992895 (Clockwise)

Preceding gene: 116694820

Following gene: 116694822

Centisome position: 34.07

GC content: 67.45

Gene sequence:

>642_bases
ATGCAGCTCTATAGTTTCTTCAACAGCTCCACGTCCTACCGGGTGCGCATCGCGCTGGCCCTCAAGGGCCTGCCGTACGA
CTACCTGCCGGTCAATATCCGCACCGGCCAGCACCGCGAGCCGGAATATGTCGGAAGCATCAACCCGTCCGCGACCGTGC
CCGCGCTGGTGGATGGCAGTTTTGCGCTCGGACAGTCGTTCGCGATCATCGACTACCTGGACGCGCTCCAGCCGGTGCCG
CGCCTGCTGCCGCAAGACCCGGTGCAGCGCGCGCGGGTGCTGGAACTGGCCACGCTGATCGGCTGCGACATCCACCCGGT
CAACAACCTGCGCGTGCTGCGCTACCTGCAGGACGTGCTGAAGGTCACGCCCGAGCAGAAGGATGCCTGGTACCGCCACT
GGATCGATGAAGGCATGGCCGGCGTGGAGCGCCTGCTGGCGCAGCACGGGCATGGCAGGTGGTGCTTCGGCGATGCGCCG
ACGCTCGCTGACGTCACGCTGGTGCCGCAAGTTGCCAACGCCCTGCGCATGGGCTGCGACCTGAGCCGGTACCAGCGCGC
GATGGCGGTCTACGCACACGCCAGCGTCCATCCCGCCTTTGCCCAGGCCGCGCCAGCGCACCAGCCCGACTACACCGCCT
GA

Upstream 100 bases:

>100_bases
TCAAGGCCGGCGAGACCATGGTCACGGGCGTGGACGGCCTCGGCGAACTGGCCGTGCGCGTGGTCTGAACCTCTGAATCG
CAGCACAGGCATTACCGATC

Downstream 100 bases:

>100_bases
CGCCACCACGCAGGCCAGGAGACAAGCATGAGCAGTACCAACAACGCGACCGGCAAGGTCCTCATCATCGGCGGCGGCAT
CGGCGGCCTCGCCGCTGCGC

Product: maleylpyruvate isomerase

Products: NA

Alternate protein names: MAAI [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MQLYSFFNSSTSYRVRIALALKGLPYDYLPVNIRTGQHREPEYVGSINPSATVPALVDGSFALGQSFAIIDYLDALQPVP
RLLPQDPVQRARVLELATLIGCDIHPVNNLRVLRYLQDVLKVTPEQKDAWYRHWIDEGMAGVERLLAQHGHGRWCFGDAP
TLADVTLVPQVANALRMGCDLSRYQRAMAVYAHASVHPAFAQAAPAHQPDYTA

Sequences:

>Translated_213_residues
MQLYSFFNSSTSYRVRIALALKGLPYDYLPVNIRTGQHREPEYVGSINPSATVPALVDGSFALGQSFAIIDYLDALQPVP
RLLPQDPVQRARVLELATLIGCDIHPVNNLRVLRYLQDVLKVTPEQKDAWYRHWIDEGMAGVERLLAQHGHGRWCFGDAP
TLADVTLVPQVANALRMGCDLSRYQRAMAVYAHASVHPAFAQAAPAHQPDYTA
>Mature_213_residues
MQLYSFFNSSTSYRVRIALALKGLPYDYLPVNIRTGQHREPEYVGSINPSATVPALVDGSFALGQSFAIIDYLDALQPVP
RLLPQDPVQRARVLELATLIGCDIHPVNNLRVLRYLQDVLKVTPEQKDAWYRHWIDEGMAGVERLLAQHGHGRWCFGDAP
TLADVTLVPQVANALRMGCDLSRYQRAMAVYAHASVHPAFAQAAPAHQPDYTA

Specific function: Forms An Equimolar Complex With The RNA Polymerase Holoenzyme (Rnap) But Not With The Core Enzyme. It Is Synthesized Predominantly When Cells Are Exposed To Amino Acid Starvation, At Which Time It Accounts For Over 50% Of The Total Protein Synthesized. It

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI22202624, Length=209, Percent_Identity=41.6267942583732, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI22202622, Length=158, Percent_Identity=39.873417721519, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17551302, Length=213, Percent_Identity=36.150234741784, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17510461, Length=208, Percent_Identity=33.1730769230769, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17556142, Length=209, Percent_Identity=36.8421052631579, Blast_Score=116, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24645375, Length=209, Percent_Identity=40.1913875598086, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI45553325, Length=209, Percent_Identity=40.1913875598086, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21355859, Length=209, Percent_Identity=40.1913875598086, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21355857, Length=211, Percent_Identity=38.8625592417062, Blast_Score=143, Evalue=7e-35,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1982 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR005955
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =5.2.1.2 [H]

Molecular weight: Translated: 23706; Mature: 23706

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLYSFFNSSTSYRVRIALALKGLPYDYLPVNIRTGQHREPEYVGSINPSATVPALVDGS
CCHHHHHCCCCCEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEECCC
FALGQSFAIIDYLDALQPVPRLLPQDPVQRARVLELATLIGCDIHPVNNLRVLRYLQDVL
HHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
KVTPEQKDAWYRHWIDEGMAGVERLLAQHGHGRWCFGDAPTLADVTLVPQVANALRMGCD
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCC
LSRYQRAMAVYAHASVHPAFAQAAPAHQPDYTA
HHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQLYSFFNSSTSYRVRIALALKGLPYDYLPVNIRTGQHREPEYVGSINPSATVPALVDGS
CCHHHHHCCCCCEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEECCC
FALGQSFAIIDYLDALQPVPRLLPQDPVQRARVLELATLIGCDIHPVNNLRVLRYLQDVL
HHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
KVTPEQKDAWYRHWIDEGMAGVERLLAQHGHGRWCFGDAPTLADVTLVPQVANALRMGCD
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCC
LSRYQRAMAVYAHASVHPAFAQAAPAHQPDYTA
HHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]