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The map label for this gene is yngJ [H]

Identifier: 116694615

GI number: 116694615

Start: 738493

End: 739656

Strand: Direct

Name: yngJ [H]

Synonym: H16_B0664

Alternate gene names: 116694615

Gene position: 738493-739656 (Clockwise)

Preceding gene: 116694614

Following gene: 116694616

Centisome position: 25.36

GC content: 72.85

Gene sequence:

>1164_bases
ATGGACTTCTCCCTTAGCCTCGAACAGCAGATGGTACGCGACAGCGCGCGCGACTACCTCGCCGCGCACAGCGATTCGGC
GGCGGTGCGGCGCGTGACCGAGGCGGGCGCCGCGCACGACGAAGCGCTGTGGCACGCGGTCGCGGGCGAACTCGGCTGGT
GCGGCATCGCACTGCCCGAAGCCGTGGGCGGCGCCGGCCTGGGGGCGCCCGGGCTGGTGCTGCTGCAGGAACAACTGGGC
CAGCGCCTGGCCTGCGTGCCGTTCTGGTCCGCCGTGTGCGTGGCCGCGCCCTGGCTTCAGGCCAGCCTGGGCCCGCGCGG
CAGCGCGCATTGGCTGGAACGGCTGGCGTGTGGCGAGCTGCGTGCCGCCGCGGTGTTGCCGGACGATGGCGGCTGGCAGT
ACGACGGCGTCGCCATTGGCGCGCAGGCGGGCGCGGATGGCTTCGTGCTGCGCGGCTGCGCCGCCCAGGTGGCCGATGCC
GCCGGCGCCGACTGGCTGCTGGTGCCGGCCCGGCTCGAAGACGGCGTGCCTGCGCTGTTCCTGCTGGAGCCAGCAGCACT
GGCACAGGATGCGCGAATCATGCTGGCGCCGCTCGATACGCTGGACCGCACGCGGCCGCAGGCCGCGCTGCGGCTGGACG
GGCTGCCCGTGCCCGCCAGCGCCTGCCTGGCGCGCGCGGACGCGGCGGCGTTTGGCCTGGCCCAGGCCTGGTGGCACGGC
AAGCTGATGCTGGCGGCGGAGCAGCTTGGCGCGGCCCAGCAATGCCTGGACCTGACCGTAGCTTATGCCTCGGAACGGAT
CCAGTTCGGGCGCGCCATCGCCTCGTTCCAGGCGGTCAAGCACCGCTGCGCGCAGATGATGGTGCTGGTCGAGGCGGCGC
GCTCGGCGGTGTATGGCGCGGCGCAGGCGTGGGAAACGGGCGAGGTGGCCGATGGTACCGGCATCCGCCTCGACATCGCC
GCCGCATCCGTGGCAGCCGACGATGCCCTGCGCTTCTGCGCGCAGGAGGCCATCCAGTTGCATGGCGGTGTCGGCTTCAC
CTGGGAATACGACCCCCAGCTCTATTTCAAGCGCGCGCAGGCCGCCAGCCACTGGCTGGGCGGTGCCGGCGCGGCGCTGG
CGTATCTCGCAGCAAATGGCCCGAACGCGTGGAGGACAGCATGA

Upstream 100 bases:

>100_bases
GATCGCGCTGGCAGCCGGCCGAACTGGGCGCAGCCGTGGCGGAACTGCTGGCGCAGGCGCAGCCGCCCCAGCCGGTCTAC
GGCAGCTGAGCGCGACGGCC

Downstream 100 bases:

>100_bases
CAGCGAATCAAGAGGCGGCATTCCGCGCCGAAGTCGCGCAGTGGATGGCCGCCAACCTGGCCGGCGAGTTCGCCTGCCTG
AAGCACCGCGGCGGCCCCGG

Product: Acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MDFSLSLEQQMVRDSARDYLAAHSDSAAVRRVTEAGAAHDEALWHAVAGELGWCGIALPEAVGGAGLGAPGLVLLQEQLG
QRLACVPFWSAVCVAAPWLQASLGPRGSAHWLERLACGELRAAAVLPDDGGWQYDGVAIGAQAGADGFVLRGCAAQVADA
AGADWLLVPARLEDGVPALFLLEPAALAQDARIMLAPLDTLDRTRPQAALRLDGLPVPASACLARADAAAFGLAQAWWHG
KLMLAAEQLGAAQQCLDLTVAYASERIQFGRAIASFQAVKHRCAQMMVLVEAARSAVYGAAQAWETGEVADGTGIRLDIA
AASVAADDALRFCAQEAIQLHGGVGFTWEYDPQLYFKRAQAASHWLGGAGAALAYLAANGPNAWRTA

Sequences:

>Translated_387_residues
MDFSLSLEQQMVRDSARDYLAAHSDSAAVRRVTEAGAAHDEALWHAVAGELGWCGIALPEAVGGAGLGAPGLVLLQEQLG
QRLACVPFWSAVCVAAPWLQASLGPRGSAHWLERLACGELRAAAVLPDDGGWQYDGVAIGAQAGADGFVLRGCAAQVADA
AGADWLLVPARLEDGVPALFLLEPAALAQDARIMLAPLDTLDRTRPQAALRLDGLPVPASACLARADAAAFGLAQAWWHG
KLMLAAEQLGAAQQCLDLTVAYASERIQFGRAIASFQAVKHRCAQMMVLVEAARSAVYGAAQAWETGEVADGTGIRLDIA
AASVAADDALRFCAQEAIQLHGGVGFTWEYDPQLYFKRAQAASHWLGGAGAALAYLAANGPNAWRTA
>Mature_387_residues
MDFSLSLEQQMVRDSARDYLAAHSDSAAVRRVTEAGAAHDEALWHAVAGELGWCGIALPEAVGGAGLGAPGLVLLQEQLG
QRLACVPFWSAVCVAAPWLQASLGPRGSAHWLERLACGELRAAAVLPDDGGWQYDGVAIGAQAGADGFVLRGCAAQVADA
AGADWLLVPARLEDGVPALFLLEPAALAQDARIMLAPLDTLDRTRPQAALRLDGLPVPASACLARADAAAFGLAQAWWHG
KLMLAAEQLGAAQQCLDLTVAYASERIQFGRAIASFQAVKHRCAQMMVLVEAARSAVYGAAQAWETGEVADGTGIRLDIA
AASVAADDALRFCAQEAIQLHGGVGFTWEYDPQLYFKRAQAASHWLGGAGAALAYLAANGPNAWRTA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=395, Percent_Identity=23.5443037974684, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI226958412, Length=369, Percent_Identity=24.1192411924119, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI4501857, Length=365, Percent_Identity=23.013698630137, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4557231, Length=388, Percent_Identity=25.5154639175258, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI187960098, Length=388, Percent_Identity=25.5154639175258, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI226958414, Length=323, Percent_Identity=24.4582043343653, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI7656849, Length=329, Percent_Identity=23.7082066869301, Blast_Score=66, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17508101, Length=382, Percent_Identity=24.0837696335079, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17506239, Length=349, Percent_Identity=24.9283667621776, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17538396, Length=366, Percent_Identity=24.8633879781421, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17534899, Length=397, Percent_Identity=25.4408060453401, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17569725, Length=397, Percent_Identity=25.9445843828715, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17533517, Length=320, Percent_Identity=23.75, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17570075, Length=387, Percent_Identity=24.031007751938, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24666513, Length=342, Percent_Identity=26.0233918128655, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355753, Length=365, Percent_Identity=24.6575342465753, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24646207, Length=334, Percent_Identity=24.8502994011976, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356377, Length=381, Percent_Identity=25.4593175853018, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 40441; Mature: 40441

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSLSLEQQMVRDSARDYLAAHSDSAAVRRVTEAGAAHDEALWHAVAGELGWCGIALPE
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEECHH
AVGGAGLGAPGLVLLQEQLGQRLACVPFWSAVCVAAPWLQASLGPRGSAHWLERLACGEL
HHCCCCCCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
RAAAVLPDDGGWQYDGVAIGAQAGADGFVLRGCAAQVADAAGADWLLVPARLEDGVPALF
CEEEECCCCCCCEECCEEEECCCCCCCCEEHHHHHHHHHCCCCCEEEEECCCCCCCCEEE
LLEPAALAQDARIMLAPLDTLDRTRPQAALRLDGLPVPASACLARADAAAFGLAQAWWHG
EECCHHHCCCCEEEEECCHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
KLMLAAEQLGAAQQCLDLTVAYASERIQFGRAIASFQAVKHRCAQMMVLVEAARSAVYGA
CCEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQAWETGEVADGTGIRLDIAAASVAADDALRFCAQEAIQLHGGVGFTWEYDPQLYFKRAQ
HHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHH
AASHWLGGAGAALAYLAANGPNAWRTA
HHHHHCCCHHHHHHEEECCCCCCCCCC
>Mature Secondary Structure
MDFSLSLEQQMVRDSARDYLAAHSDSAAVRRVTEAGAAHDEALWHAVAGELGWCGIALPE
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEECHH
AVGGAGLGAPGLVLLQEQLGQRLACVPFWSAVCVAAPWLQASLGPRGSAHWLERLACGEL
HHCCCCCCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
RAAAVLPDDGGWQYDGVAIGAQAGADGFVLRGCAAQVADAAGADWLLVPARLEDGVPALF
CEEEECCCCCCCEECCEEEECCCCCCCCEEHHHHHHHHHCCCCCEEEEECCCCCCCCEEE
LLEPAALAQDARIMLAPLDTLDRTRPQAALRLDGLPVPASACLARADAAAFGLAQAWWHG
EECCHHHCCCCEEEEECCHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
KLMLAAEQLGAAQQCLDLTVAYASERIQFGRAIASFQAVKHRCAQMMVLVEAARSAVYGA
CCEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQAWETGEVADGTGIRLDIAAASVAADDALRFCAQEAIQLHGGVGFTWEYDPQLYFKRAQ
HHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHH
AASHWLGGAGAALAYLAANGPNAWRTA
HHHHHCCCHHHHHHEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]