Click here to switch to the map view.

The map label for this gene is atoD [C]

Identifier: 116694606

GI number: 116694606

Start: 729671

End: 730561

Strand: Direct

Name: atoD [C]

Synonym: H16_B0655

Alternate gene names: 116694606

Gene position: 729671-730561 (Clockwise)

Preceding gene: 116694605

Following gene: 116694607

Centisome position: 25.05

GC content: 70.26

Gene sequence:

>891_bases
ATGACCAAGACAATCGACAAGATCATGAGCGCGGCCGACGTGGTCGGCCAGCTCGCCGACGGCATGACCATCGGCATCGG
TGGGTGGGGCCCGCGCCGCAAGCCGATGGCGCTGGTGCGCGAGATCCTGCGCTCGCCGCTGAAGGACCTGACCGTGGTCG
CCTACGGCGGCCCCGAGGTGGGCATGCTGTGCGCGGCCGGCAAGGTGCGCCGGCTGGTGTTCGGCTTCGTCTCGCTCGAC
GTGATTCCGCTCGAGCCCTACTTCCGCCAGGCGCGCGAGCGCGGCGTGCTGGAAGTGATGGAGCTTGACGAAGGCATGCT
GCAGCTGGGCCTGCGCGCCGCGGCCGCGCGCCTGCCGTTCCTGCCGACGCGCGCCGCGCTGGGCACCGACGTGCTGGACA
TGAACCCCCAGCTGAGGACGGTGCGTTCGCCCTATGCCGATGGCGAAGTGCTGTTGGCGATGCCGGCGATCGAGCTCGAT
GCCGCGCTGCTGCACGTGAACGACAGCGATGTGCTCGGCAACACCCGCATCGACGGGCCCGATCCGTTCTTCGATGAATG
GTTCGCACGCGCCGCGCACCGCTGCTATGTGAGCTGCGAAGCGCTGCACCTGCGCCTGGAGGATGAAGACCTGGCGCGCG
CGCGCAACAACGCCTTCGAGCGCTCGCTGGTAAGCGGCGTGGTGCACGCACCCGGCGGCGCCCATCCCACTTCCTGCGCG
CCGGCCTACGGCTGGGACCTGCCCGCGCTGAAGGCGTACTGCGCCGGCGCCGAGGCCGAGGACGGCTTCCGTGCCTACCG
CGACGAGGTGGTGGGCGCGAGCGAAGCGGCCTACCTGGAGCGCATCGGCGGCCTTGGCCACGTGCACGACCTGCCGCTGC
CGGTACTTTGA

Upstream 100 bases:

>100_bases
GGCGGCCTGGAGGTGGACTGGAGCCACCACGCCGCCTACGAGGCCACGCGCGTCAGCCTGTGGGGACACGACTTCAGCAT
CGGATACCGCTAAACACATC

Downstream 100 bases:

>100_bases
ACCCGCCAACCCAAGGAGCGACCGTGAGCGCCACTTATGAATTCACCCGCGCCGAGCTGATGATTGCCGCCGCCGCCCGC
GAATGGCGCGACGACGGCGA

Product: Acyl CoA:acetate/3-ketoacid CoA transferase,alpha subunit

Products: Acetate; Butanoyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTKTIDKIMSAADVVGQLADGMTIGIGGWGPRRKPMALVREILRSPLKDLTVVAYGGPEVGMLCAAGKVRRLVFGFVSLD
VIPLEPYFRQARERGVLEVMELDEGMLQLGLRAAAARLPFLPTRAALGTDVLDMNPQLRTVRSPYADGEVLLAMPAIELD
AALLHVNDSDVLGNTRIDGPDPFFDEWFARAAHRCYVSCEALHLRLEDEDLARARNNAFERSLVSGVVHAPGGAHPTSCA
PAYGWDLPALKAYCAGAEAEDGFRAYRDEVVGASEAAYLERIGGLGHVHDLPLPVL

Sequences:

>Translated_296_residues
MTKTIDKIMSAADVVGQLADGMTIGIGGWGPRRKPMALVREILRSPLKDLTVVAYGGPEVGMLCAAGKVRRLVFGFVSLD
VIPLEPYFRQARERGVLEVMELDEGMLQLGLRAAAARLPFLPTRAALGTDVLDMNPQLRTVRSPYADGEVLLAMPAIELD
AALLHVNDSDVLGNTRIDGPDPFFDEWFARAAHRCYVSCEALHLRLEDEDLARARNNAFERSLVSGVVHAPGGAHPTSCA
PAYGWDLPALKAYCAGAEAEDGFRAYRDEVVGASEAAYLERIGGLGHVHDLPLPVL
>Mature_295_residues
TKTIDKIMSAADVVGQLADGMTIGIGGWGPRRKPMALVREILRSPLKDLTVVAYGGPEVGMLCAAGKVRRLVFGFVSLDV
IPLEPYFRQARERGVLEVMELDEGMLQLGLRAAAARLPFLPTRAALGTDVLDMNPQLRTVRSPYADGEVLLAMPAIELDA
ALLHVNDSDVLGNTRIDGPDPFFDEWFARAAHRCYVSCEALHLRLEDEDLARARNNAFERSLVSGVVHAPGGAHPTSCAP
AYGWDLPALKAYCAGAEAEDGFRAYRDEVVGASEAAYLERIGGLGHVHDLPLPVL

Specific function: Probable subunit of a CoA-transferase composed of Rv3551 and Rv3552 [H]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004165 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: 2.8.3.8 [C]

Molecular weight: Translated: 32013; Mature: 31882

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTIDKIMSAADVVGQLADGMTIGIGGWGPRRKPMALVREILRSPLKDLTVVAYGGPEV
CCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCHHHEEEEEECCCCC
GMLCAAGKVRRLVFGFVSLDVIPLEPYFRQARERGVLEVMELDEGMLQLGLRAAAARLPF
CHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
LPTRAALGTDVLDMNPQLRTVRSPYADGEVLLAMPAIELDAALLHVNDSDVLGNTRIDGP
CCCHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEECCHHHCEEEEEECCCCCCCCCCCCCC
DPFFDEWFARAAHRCYVSCEALHLRLEDEDLARARNNAFERSLVSGVVHAPGGAHPTSCA
CCHHHHHHHHHHHHHHEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PAYGWDLPALKAYCAGAEAEDGFRAYRDEVVGASEAAYLERIGGLGHVHDLPLPVL
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKTIDKIMSAADVVGQLADGMTIGIGGWGPRRKPMALVREILRSPLKDLTVVAYGGPEV
CHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCHHHEEEEEECCCCC
GMLCAAGKVRRLVFGFVSLDVIPLEPYFRQARERGVLEVMELDEGMLQLGLRAAAARLPF
CHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
LPTRAALGTDVLDMNPQLRTVRSPYADGEVLLAMPAIELDAALLHVNDSDVLGNTRIDGP
CCCHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEECCHHHCEEEEEECCCCCCCCCCCCCC
DPFFDEWFARAAHRCYVSCEALHLRLEDEDLARARNNAFERSLVSGVVHAPGGAHPTSCA
CCHHHHHHHHHHHHHHEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PAYGWDLPALKAYCAGAEAEDGFRAYRDEVVGASEAAYLERIGGLGHVHDLPLPVL
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Butyrate [C]

Specific reaction: Acetyl-CoA + Butyrate (n-C4:0) --> Acetate + Butanoyl-CoA [C]

General reaction: Coenzyme A transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]