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The map label for this gene is yngJ [H]

Identifier: 116694336

GI number: 116694336

Start: 434770

End: 435915

Strand: Direct

Name: yngJ [H]

Synonym: H16_B0383

Alternate gene names: 116694336

Gene position: 434770-435915 (Clockwise)

Preceding gene: 116694335

Following gene: 116694337

Centisome position: 14.93

GC content: 66.14

Gene sequence:

>1146_bases
ATGGACTTGCTCTACTCGGAGGAGCACAAGGCGTTCCGGCAGGAAGTGCGCGACTTTCTCGCCGCCAACCTGCCGGACGA
CATGCGCGAGCGCCTGCGCGCCGGCGGCTTCGCCACCAAGGACGACAACGCACTCTGGCAACGCAGGCTGAACCAGCGCG
GCTGGGGCGCGCCCGCCTGGCCGAAGGCATTTGGCGGCGCCGGCTGGGACGCCGACCGCCAGCGCATCTTCGCCGACGAA
TGCGCTGCCGCGCCGGCACCGACGCCGCACCCGTTCAACATCACCATGCTGGGGCCGGTGCTGATCCACTTCGGCTCCGA
CGTGCAGCGTGAGTATTTCCTGCCCAAGCTTCTGAACGCCGACATCCAGGTCTGCCAGGGATTCTCGGAACCGGGCTCCG
GCTCCGACCTTGCCTCGCTGAAGACCACGGCTGTTCGCGAAGGCAATGAGTACATCGTCAACGGCCAGAAGATCTGGACG
AGCCAGGCGCATTACGCGGACTGGGCCTTCTGCCTGGTGCGGACCGACGTCGACGCGGTGAAGAAGCAGGCCGGCATCTC
GTTCCTGCTGATCGACATGAAGTCGCCGGGCATCACCGTGCGCCCGATCATCAGCATCGACGGCCGCCACAGCCTGAACG
AAGTCTTCTTCGAGAACGTGCGCGTGCCTGCCGACAACCTGGTGGGCGAGGAGAACAAGGGCTGGAGCTACGCCAAGTTC
CTGCTCGGCCACGAGCGCGCCCACATCGCCGGCATCGGCCGCAACAAGGAGCGCGTGGCCTGTGCCAGGGCGCTGCTGGC
GAAGATGGAGGACGAGGGCTACCCGGAGGCGACGCTGGCAGCCTATCGCGGACGGATTGCCATGATCGAAGCCGACCTGC
ATGCGCTGGAAGTGACGCAACTGCGCGTGCACGGCGGGCACGCCGACGCGAAGCTGTCGCCGATGCTGAAGGTTCGCGGC
AGCGAGATCTTCCAGGCCGTCACCGACCTGCTTTGCCGGATGACCGGCACCGGTTCGCTGCCCGCCGACGGCGCCGACGT
GACGCTGACCCGGTCCTACCTGTACTCGCGCGCCGTCTCGATCTTCGGCGGTACCACCGAAGTGCAGAAGAATATCCTTT
CCGCTTCCCTCCTGGATCTGTCATGA

Upstream 100 bases:

>100_bases
AACCACCAGCGCTCCCATGACATGCGCGAGGGCTTGCTGGCCTTCGCCGAAAAGCGGCAGCCCGTCTTCAAGGGCTGCTG
AACCGACACAAGGAACCACC

Downstream 100 bases:

>100_bases
ACCTGCAACTGAACGACGTCCAGCAGCAACTGCAGGACAGCCTGGGGCGGCTGCTGGCCCGCGAGTACGACTTCGGCCGC
CGCCAGCAATATGCGGCGTC

Product: Acyl-CoA dehydrogenase

Products: 6-carboxyhex-2-enoyl-CoA; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MDLLYSEEHKAFRQEVRDFLAANLPDDMRERLRAGGFATKDDNALWQRRLNQRGWGAPAWPKAFGGAGWDADRQRIFADE
CAAAPAPTPHPFNITMLGPVLIHFGSDVQREYFLPKLLNADIQVCQGFSEPGSGSDLASLKTTAVREGNEYIVNGQKIWT
SQAHYADWAFCLVRTDVDAVKKQAGISFLLIDMKSPGITVRPIISIDGRHSLNEVFFENVRVPADNLVGEENKGWSYAKF
LLGHERAHIAGIGRNKERVACARALLAKMEDEGYPEATLAAYRGRIAMIEADLHALEVTQLRVHGGHADAKLSPMLKVRG
SEIFQAVTDLLCRMTGTGSLPADGADVTLTRSYLYSRAVSIFGGTTEVQKNILSASLLDLS

Sequences:

>Translated_381_residues
MDLLYSEEHKAFRQEVRDFLAANLPDDMRERLRAGGFATKDDNALWQRRLNQRGWGAPAWPKAFGGAGWDADRQRIFADE
CAAAPAPTPHPFNITMLGPVLIHFGSDVQREYFLPKLLNADIQVCQGFSEPGSGSDLASLKTTAVREGNEYIVNGQKIWT
SQAHYADWAFCLVRTDVDAVKKQAGISFLLIDMKSPGITVRPIISIDGRHSLNEVFFENVRVPADNLVGEENKGWSYAKF
LLGHERAHIAGIGRNKERVACARALLAKMEDEGYPEATLAAYRGRIAMIEADLHALEVTQLRVHGGHADAKLSPMLKVRG
SEIFQAVTDLLCRMTGTGSLPADGADVTLTRSYLYSRAVSIFGGTTEVQKNILSASLLDLS
>Mature_381_residues
MDLLYSEEHKAFRQEVRDFLAANLPDDMRERLRAGGFATKDDNALWQRRLNQRGWGAPAWPKAFGGAGWDADRQRIFADE
CAAAPAPTPHPFNITMLGPVLIHFGSDVQREYFLPKLLNADIQVCQGFSEPGSGSDLASLKTTAVREGNEYIVNGQKIWT
SQAHYADWAFCLVRTDVDAVKKQAGISFLLIDMKSPGITVRPIISIDGRHSLNEVFFENVRVPADNLVGEENKGWSYAKF
LLGHERAHIAGIGRNKERVACARALLAKMEDEGYPEATLAAYRGRIAMIEADLHALEVTQLRVHGGHADAKLSPMLKVRG
SEIFQAVTDLLCRMTGTGSLPADGADVTLTRSYLYSRAVSIFGGTTEVQKNILSASLLDLS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=250, Percent_Identity=30, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI4501857, Length=393, Percent_Identity=26.2086513994911, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI4557233, Length=334, Percent_Identity=28.4431137724551, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI226958414, Length=220, Percent_Identity=29.0909090909091, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI187960098, Length=240, Percent_Identity=27.9166666666667, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI7656849, Length=388, Percent_Identity=27.319587628866, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4557231, Length=240, Percent_Identity=27.5, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4557235, Length=290, Percent_Identity=27.9310344827586, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI4501859, Length=222, Percent_Identity=30.6306306306306, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI76496475, Length=290, Percent_Identity=27.9310344827586, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI38505218, Length=286, Percent_Identity=26.2237762237762, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI211971008, Length=286, Percent_Identity=26.5734265734266, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI48976061, Length=286, Percent_Identity=26.5734265734266, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI21361497, Length=298, Percent_Identity=26.1744966442953, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI87081958, Length=259, Percent_Identity=29.7297297297297, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551932, Length=392, Percent_Identity=26.530612244898, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17570075, Length=260, Percent_Identity=30.3846153846154, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17505929, Length=333, Percent_Identity=28.5285285285285, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=399, Percent_Identity=26.0651629072682, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=168, Percent_Identity=33.9285714285714, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538396, Length=383, Percent_Identity=23.2375979112272, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=189, Percent_Identity=29.6296296296296, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17569725, Length=215, Percent_Identity=30.2325581395349, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562446, Length=182, Percent_Identity=31.8681318681319, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=194, Percent_Identity=29.8969072164948, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=183, Percent_Identity=30.0546448087432, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71985184, Length=153, Percent_Identity=31.3725490196078, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=249, Percent_Identity=26.9076305220884, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=152, Percent_Identity=30.2631578947368, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356377, Length=392, Percent_Identity=27.2959183673469, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24660351, Length=339, Percent_Identity=23.3038348082596, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24646207, Length=392, Percent_Identity=25.2551020408163, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24666513, Length=158, Percent_Identity=33.5443037974684, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21355753, Length=233, Percent_Identity=28.755364806867, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281363737, Length=153, Percent_Identity=29.4117647058824, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.1.62

Molecular weight: Translated: 41973; Mature: 41973

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLYSEEHKAFRQEVRDFLAANLPDDMRERLRAGGFATKDDNALWQRRLNQRGWGAPAW
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCC
PKAFGGAGWDADRQRIFADECAAAPAPTPHPFNITMLGPVLIHFGSDVQREYFLPKLLNA
CHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHCC
DIQVCQGFSEPGSGSDLASLKTTAVREGNEYIVNGQKIWTSQAHYADWAFCLVRTDVDAV
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEECCEEEECCCCCCCCEEEEEEECCHHHH
KKQAGISFLLIDMKSPGITVRPIISIDGRHSLNEVFFENVRVPADNLVGEENKGWSYAKF
HHHCCCEEEEEEECCCCEEEEEEEEECCCCHHHHHHHHCCCCCHHHHCCCCCCCCHHHHH
LLGHERAHIAGIGRNKERVACARALLAKMEDEGYPEATLAAYRGRIAMIEADLHALEVTQ
HHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCEEEEEECCCCEEEEEE
LRVHGGHADAKLSPMLKVRGSEIFQAVTDLLCRMTGTGSLPADGADVTLTRSYLYSRAVS
EEEECCCCCCCCCHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHH
IFGGTTEVQKNILSASLLDLS
HCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLLYSEEHKAFRQEVRDFLAANLPDDMRERLRAGGFATKDDNALWQRRLNQRGWGAPAW
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCC
PKAFGGAGWDADRQRIFADECAAAPAPTPHPFNITMLGPVLIHFGSDVQREYFLPKLLNA
CHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHCC
DIQVCQGFSEPGSGSDLASLKTTAVREGNEYIVNGQKIWTSQAHYADWAFCLVRTDVDAV
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEECCEEEECCCCCCCCEEEEEEECCHHHH
KKQAGISFLLIDMKSPGITVRPIISIDGRHSLNEVFFENVRVPADNLVGEENKGWSYAKF
HHHCCCEEEEEEECCCCEEEEEEEEECCCCHHHHHHHHCCCCCHHHHCCCCCCCCHHHHH
LLGHERAHIAGIGRNKERVACARALLAKMEDEGYPEATLAAYRGRIAMIEADLHALEVTQ
HHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCEEEEEECCCCEEEEEE
LRVHGGHADAKLSPMLKVRGSEIFQAVTDLLCRMTGTGSLPADGADVTLTRSYLYSRAVS
EEEECCCCCCCCCHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHH
IFGGTTEVQKNILSASLLDLS
HCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: pimeloyl-CoA; NAD+

Specific reaction: pimeloyl-CoA + NAD+ = 6-carboxyhex-2-enoyl-CoA + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]