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The map label for this gene is ndhH

Identifier: 113478174

GI number: 113478174

Start: 7406254

End: 7407438

Strand: Reverse

Name: ndhH

Synonym: Tery_4815

Alternate gene names: 113478174

Gene position: 7407438-7406254 (Counterclockwise)

Preceding gene: 113478180

Following gene: 113478173

Centisome position: 95.58

GC content: 41.94

Gene sequence:

>1185_bases
ATGAGCCAAATTCAAACTAGAACCGAGCCCATGGTCATTAACATGGGGCCTCATCATCCCTCAATGCATGGGGTATTAAG
GTTGATTGTTACTTTAGATGGAGAAGATGTAATTGACTGTGAACCTGTAATTGGTTACTTACACAGGGGCATGGAAAAGA
TTGCGGAAAACCGCACTAATACAATGTTTGTTCCTTACGTTAGTCGTTGGGATTATGCTGCGGGAATGTTTAATGAGGCC
GTAACAGTAAATGCTCCGGAACAACTGGCCGACATAGCAGTTCCTAAAAGGGCTAGTTATATCCGGGTAATTATGCTGGA
ACTAAACCGGATTGCTAATCACTTGTTATGGCTTGGCCCATTCCTGGCGGATGTCGGGGCCCAAACTCCTTTCTTCTACA
TCTTCCGAGAAAGGGAAATGATTTATGACTTGTGGGAAGCTGCTACAGGTTATCGAATGGTAAACAATAATTATTTCCGT
ATTGGTGGGGTAGCTGCTGATTTGCCTTATGGTTGGGTGGATAAGTGCGAAGATTTTTGTGATTATTTTTTACCCAAGGT
TGATGAGTATGAACGTCTGATTACTAATAACCCAATTTTCCGTCGCCGAATTATGGGATTAGGTGTAATTAGTCGGGAAG
AGGCGATTAACTGGGGACTTTCTGGACCTATGTTGCGAGCTTCTGGGGTAAAGTGGGATTTACGGAAGGTTGACCATTAT
GAGTGTTATGACGATTTTGACTGGGAAGTTCACTGGGAAAAAGATGGAGATTGTTTGGCGCGATATCTCGTGCGGATTCG
AGAAATGCGAGAGTCGGTTAATATTATTCGTCAAGCTATTAAAGGACTTCCTGGTGGGCCTTATGAAAATCTGGAAGCTA
AACGGATGGCTGAGGGGCCTAAGTCCGAGTGGAATGATTTTGATTACCAATTTTTAGGTAAAAAAATTCCTCCGACTTTT
AAGATTCCTAAAGGTGAGCATTATGTTCGCATTGAAAGTGGTAAGGGAGAGATTGGAATTTATATTATTGGTGATAATAA
TATTTTTCCTTGGCGTTTTAAGATTCGGGCGGCAGATTTCGTAAATTTGCAGATTTTTCCTCATATTTTGCAGGGTGCGA
AAGTGGCGGATCTTGTGGCTATTTTAGGTAGTATTGACATTATTATGGGGTCTGTGGATCGATAG

Upstream 100 bases:

>100_bases
TATTGCTCCTCACAAAACATAATAGCATTTAGCCTCAAAAAACTCAGGCCAAATAATTGGAAAGAAACATTAAATATTAC
TCATTAGGAGAATAGTCAAG

Downstream 100 bases:

>100_bases
TAAGATCAATTGTTAAAAGGTAAAATTTAAAAGTCACAAAAGTAAGCATTCAGCATTCAGTATGCTTCCTAAATAGTAAC
TTTACTAGCTTATGAGTTAT

Product: NAD(P)H-quinone oxidoreductase subunit H

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase subunit H; NADH-plastoquinone oxidoreductase subunit H; NDH-1 subunit H; NDH-H

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MSQIQTRTEPMVINMGPHHPSMHGVLRLIVTLDGEDVIDCEPVIGYLHRGMEKIAENRTNTMFVPYVSRWDYAAGMFNEA
VTVNAPEQLADIAVPKRASYIRVIMLELNRIANHLLWLGPFLADVGAQTPFFYIFREREMIYDLWEAATGYRMVNNNYFR
IGGVAADLPYGWVDKCEDFCDYFLPKVDEYERLITNNPIFRRRIMGLGVISREEAINWGLSGPMLRASGVKWDLRKVDHY
ECYDDFDWEVHWEKDGDCLARYLVRIREMRESVNIIRQAIKGLPGGPYENLEAKRMAEGPKSEWNDFDYQFLGKKIPPTF
KIPKGEHYVRIESGKGEIGIYIIGDNNIFPWRFKIRAADFVNLQIFPHILQGAKVADLVAILGSIDIIMGSVDR

Sequences:

>Translated_394_residues
MSQIQTRTEPMVINMGPHHPSMHGVLRLIVTLDGEDVIDCEPVIGYLHRGMEKIAENRTNTMFVPYVSRWDYAAGMFNEA
VTVNAPEQLADIAVPKRASYIRVIMLELNRIANHLLWLGPFLADVGAQTPFFYIFREREMIYDLWEAATGYRMVNNNYFR
IGGVAADLPYGWVDKCEDFCDYFLPKVDEYERLITNNPIFRRRIMGLGVISREEAINWGLSGPMLRASGVKWDLRKVDHY
ECYDDFDWEVHWEKDGDCLARYLVRIREMRESVNIIRQAIKGLPGGPYENLEAKRMAEGPKSEWNDFDYQFLGKKIPPTF
KIPKGEHYVRIESGKGEIGIYIIGDNNIFPWRFKIRAADFVNLQIFPHILQGAKVADLVAILGSIDIIMGSVDR
>Mature_393_residues
SQIQTRTEPMVINMGPHHPSMHGVLRLIVTLDGEDVIDCEPVIGYLHRGMEKIAENRTNTMFVPYVSRWDYAAGMFNEAV
TVNAPEQLADIAVPKRASYIRVIMLELNRIANHLLWLGPFLADVGAQTPFFYIFREREMIYDLWEAATGYRMVNNNYFRI
GGVAADLPYGWVDKCEDFCDYFLPKVDEYERLITNNPIFRRRIMGLGVISREEAINWGLSGPMLRASGVKWDLRKVDHYE
CYDDFDWEVHWEKDGDCLARYLVRIREMRESVNIIRQAIKGLPGGPYENLEAKRMAEGPKSEWNDFDYQFLGKKIPPTFK
IPKGEHYVRIESGKGEIGIYIIGDNNIFPWRFKIRAADFVNLQIFPHILQGAKVADLVAILGSIDIIMGSVDR

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=388, Percent_Identity=42.0103092783505, Blast_Score=297, Evalue=1e-80,
Organism=Homo sapiens, GI260898743, Length=382, Percent_Identity=41.3612565445026, Blast_Score=286, Evalue=2e-77,
Organism=Escherichia coli, GI145693162, Length=388, Percent_Identity=39.1752577319588, Blast_Score=294, Evalue=7e-81,
Organism=Escherichia coli, GI1789076, Length=391, Percent_Identity=31.4578005115089, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788832, Length=391, Percent_Identity=28.1329923273657, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17568379, Length=400, Percent_Identity=41.5, Blast_Score=313, Evalue=9e-86,
Organism=Caenorhabditis elegans, GI17555284, Length=397, Percent_Identity=41.0579345088161, Blast_Score=312, Evalue=2e-85,
Organism=Drosophila melanogaster, GI221459469, Length=390, Percent_Identity=43.8461538461538, Blast_Score=331, Evalue=4e-91,
Organism=Drosophila melanogaster, GI24638644, Length=396, Percent_Identity=40.6565656565657, Blast_Score=315, Evalue=3e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NDHH_TRIEI (Q10VG2)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_724235.1
- ProteinModelPortal:   Q10VG2
- SMR:   Q10VG2
- STRING:   Q10VG2
- GeneID:   4246469
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_4815
- NMPDR:   fig|203124.1.peg.1930
- eggNOG:   COG0649
- HOGENOM:   HBG459705
- OMA:   ILNMGPQ
- PhylomeDB:   Q10VG2
- ProtClustDB:   PRK07415
- BioCyc:   TERY203124:TERY_4815-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01358
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885

Pfam domain/function: PF00346 Complex1_49kDa

EC number: 1.6.5.3

Molecular weight: Translated: 45438; Mature: 45307

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQIQTRTEPMVINMGPHHPSMHGVLRLIVTLDGEDVIDCEPVIGYLHRGMEKIAENRTN
CCCCCCCCCCEEEEECCCCCHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCC
TMFVPYVSRWDYAAGMFNEAVTVNAPEQLADIAVPKRASYIRVIMLELNRIANHLLWLGP
EEEEEECCCCCHHHHHCCCCEEECCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FLADVGAQTPFFYIFREREMIYDLWEAATGYRMVNNNYFRIGGVAADLPYGWVDKCEDFC
HHHHHCCCCCEEEEEEHHHHHHHHHHHHCCEEEECCCEEEECCEEECCCCCHHHHHHHHH
DYFLPKVDEYERLITNNPIFRRRIMGLGVISREEAINWGLSGPMLRASGVKWDLRKVDHY
HHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCCCCCEEECCCCEEEHHCCCCC
ECYDDFDWEVHWEKDGDCLARYLVRIREMRESVNIIRQAIKGLPGGPYENLEAKRMAEGP
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCC
KSEWNDFDYQFLGKKIPPTFKIPKGEHYVRIESGKGEIGIYIIGDNNIFPWRFKIRAADF
CCCCCCCCHHHHCCCCCCCEECCCCCEEEEEECCCCCEEEEEEECCCEEEEEEEEEECEE
VNLQIFPHILQGAKVADLVAILGSIDIIMGSVDR
EEEEEHHHHHCCCHHHHHHHHHHHHHHEECCCCC
>Mature Secondary Structure 
SQIQTRTEPMVINMGPHHPSMHGVLRLIVTLDGEDVIDCEPVIGYLHRGMEKIAENRTN
CCCCCCCCCEEEEECCCCCHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCC
TMFVPYVSRWDYAAGMFNEAVTVNAPEQLADIAVPKRASYIRVIMLELNRIANHLLWLGP
EEEEEECCCCCHHHHHCCCCEEECCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FLADVGAQTPFFYIFREREMIYDLWEAATGYRMVNNNYFRIGGVAADLPYGWVDKCEDFC
HHHHHCCCCCEEEEEEHHHHHHHHHHHHCCEEEECCCEEEECCEEECCCCCHHHHHHHHH
DYFLPKVDEYERLITNNPIFRRRIMGLGVISREEAINWGLSGPMLRASGVKWDLRKVDHY
HHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCCCCCEEECCCCEEEHHCCCCC
ECYDDFDWEVHWEKDGDCLARYLVRIREMRESVNIIRQAIKGLPGGPYENLEAKRMAEGP
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCC
KSEWNDFDYQFLGKKIPPTFKIPKGEHYVRIESGKGEIGIYIIGDNNIFPWRFKIRAADF
CCCCCCCCHHHHCCCCCCCEECCCCCEEEEEECCCCCEEEEEEECCCEEEEEEEEEECEE
VNLQIFPHILQGAKVADLVAILGSIDIIMGSVDR
EEEEEHHHHHCCCHHHHHHHHHHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA