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The map label for this gene is nlpI [C]

Identifier: 113478010

GI number: 113478010

Start: 7112497

End: 7113855

Strand: Reverse

Name: nlpI [C]

Synonym: Tery_4626

Alternate gene names: 113478010

Gene position: 7113855-7112497 (Counterclockwise)

Preceding gene: 113478012

Following gene: 113478006

Centisome position: 91.79

GC content: 33.11

Gene sequence:

>1359_bases
ATGAAAATAATTAAAGGGAACAGGGTTAAGGAACTCAGAAATTTTTTTTGTAATCAGAGTTTGATAATTTCTCGAAAAAA
AATTGGCTGGAAAATTTGGGGTTTTAGACCTAATGATAATTATTTTGAGAAGGGTTATAAGGGTTTTACTCTGAGTTTGC
TTAGGTTAGTTTCTACTCTAATTTTAACTGTTATAGTTTCTATGAGTGACAGTATTGCTTATGGTCAAAATCAAAGTTTT
GATAATTATCAAAAAAGAAAATCTTTGATTTTTTTGAGTCAAAACCAAGAACAAGTTGAAGATTTTAAACTAAGAGAAGA
AATTCGCGATGGTGTCCGAGAGGAGGTAGATTATACTTTTCGTCATGCTATGTCATTACTTAGTGTTTTTCTAATTGTTT
TGACTTTTTTCCCGGCTTCAGCGGCAGTTTGGATTTGGTTTCTTCAGGCAAAGTTAGCTCACAAAGTTGATGTTACAAAA
CAAGAGATTGATAGTTTTAAATATGATACAGTATCTCAACTTAAACAAATTATTGTTGATACTCAGGTTATTTTAGATGA
ATTGAGGGTAGAAAGTGGCAAGGCTGAGGAAAAAATTGAACAACTTCAACAGGATACTTTGATTCAATTTTCTTCTGAAC
AAGGTGATAATTCTGAGCCTTTAATGATGGCGAAAGACTATGCAAAAAAAGCTGATACTTTTTTCTTTTCGGGTCAGTTT
AAGGAGGCTATTAATGCTTATAATCAAGCTTTAAAAATTCATCCAAAAATGGCGGATGTTTGGAATAATCGGGGTGTGGC
TTTGACAAGATTAAAGATATTTGATGAGGCAATTTCTTCTTATGATCGAGCTTTACAAATTCGGGCTGATTATGCGGATG
CTTGGAATAATAGGGGTGTTTGTTTGATAGAATTGCAGCATTATCAAGAGGCAATTAATTCTTTTGAGCAAGGAATTAAG
GTTAAACCTGATTATGCAGATGCTTGGAATAATAGGGGTGTTTGTTTGGCAAAAATTCAAAAATATCAGGAGGCAGTTAA
GTCTTATAATCAGGCAATTGCTATTAAAAATGATTATGGTGATGCTTGGAATAATCGCGGTGCTTGTTTGATGAAGTTGG
GAATTTATGGAGAGGCGATCGCTTGTTTTGATAATGCTGTAAAGATTCAACCTGACTTTTTTAGTGCTTGGTATAATCAG
GCTCGTTGTTATAGTTTAAAGGGTGATGTTGATATGGCTTTAAAAAGTTTTGAAAAGGCTGTTAGTTTGAATGGTAAAAA
GTCTCAAAAGATGGCAAAAAATGAACCTGATTTTGATAATATTCGGGACCATGAATTGTTTCAGAAGTTGATAGTTTGA

Upstream 100 bases:

>100_bases
TTATTATATTTAAGTGCCTTTGGGTTTAATGGGCAATTCCTAATTAGAATTAATTCTATGGATGAAAATATTATTAGTTA
ATCTGGGCTTTTAAAAGGTA

Downstream 100 bases:

>100_bases
TTGTCTTTTTAGTTAAGGTTTAAAGGTCAAAAGTTGGAAGCCCTGTAGGTTGGGTCTCAGAATGTTAGCCCAGCTTTTCT
GCAAGATAAACTTAACAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKIIKGNRVKELRNFFCNQSLIISRKKIGWKIWGFRPNDNYFEKGYKGFTLSLLRLVSTLILTVIVSMSDSIAYGQNQSF
DNYQKRKSLIFLSQNQEQVEDFKLREEIRDGVREEVDYTFRHAMSLLSVFLIVLTFFPASAAVWIWFLQAKLAHKVDVTK
QEIDSFKYDTVSQLKQIIVDTQVILDELRVESGKAEEKIEQLQQDTLIQFSSEQGDNSEPLMMAKDYAKKADTFFFSGQF
KEAINAYNQALKIHPKMADVWNNRGVALTRLKIFDEAISSYDRALQIRADYADAWNNRGVCLIELQHYQEAINSFEQGIK
VKPDYADAWNNRGVCLAKIQKYQEAVKSYNQAIAIKNDYGDAWNNRGACLMKLGIYGEAIACFDNAVKIQPDFFSAWYNQ
ARCYSLKGDVDMALKSFEKAVSLNGKKSQKMAKNEPDFDNIRDHELFQKLIV

Sequences:

>Translated_452_residues
MKIIKGNRVKELRNFFCNQSLIISRKKIGWKIWGFRPNDNYFEKGYKGFTLSLLRLVSTLILTVIVSMSDSIAYGQNQSF
DNYQKRKSLIFLSQNQEQVEDFKLREEIRDGVREEVDYTFRHAMSLLSVFLIVLTFFPASAAVWIWFLQAKLAHKVDVTK
QEIDSFKYDTVSQLKQIIVDTQVILDELRVESGKAEEKIEQLQQDTLIQFSSEQGDNSEPLMMAKDYAKKADTFFFSGQF
KEAINAYNQALKIHPKMADVWNNRGVALTRLKIFDEAISSYDRALQIRADYADAWNNRGVCLIELQHYQEAINSFEQGIK
VKPDYADAWNNRGVCLAKIQKYQEAVKSYNQAIAIKNDYGDAWNNRGACLMKLGIYGEAIACFDNAVKIQPDFFSAWYNQ
ARCYSLKGDVDMALKSFEKAVSLNGKKSQKMAKNEPDFDNIRDHELFQKLIV
>Mature_452_residues
MKIIKGNRVKELRNFFCNQSLIISRKKIGWKIWGFRPNDNYFEKGYKGFTLSLLRLVSTLILTVIVSMSDSIAYGQNQSF
DNYQKRKSLIFLSQNQEQVEDFKLREEIRDGVREEVDYTFRHAMSLLSVFLIVLTFFPASAAVWIWFLQAKLAHKVDVTK
QEIDSFKYDTVSQLKQIIVDTQVILDELRVESGKAEEKIEQLQQDTLIQFSSEQGDNSEPLMMAKDYAKKADTFFFSGQF
KEAINAYNQALKIHPKMADVWNNRGVALTRLKIFDEAISSYDRALQIRADYADAWNNRGVCLIELQHYQEAINSFEQGIK
VKPDYADAWNNRGVCLAKIQKYQEAVKSYNQAIAIKNDYGDAWNNRGACLMKLGIYGEAIACFDNAVKIQPDFFSAWYNQ
ARCYSLKGDVDMALKSFEKAVSLNGKKSQKMAKNEPDFDNIRDHELFQKLIV

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=183, Percent_Identity=32.2404371584699, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI32307150, Length=183, Percent_Identity=32.2404371584699, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI83415184, Length=189, Percent_Identity=33.8624338624339, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI301336134, Length=189, Percent_Identity=33.8624338624339, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI118766330, Length=191, Percent_Identity=29.3193717277487, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI118766328, Length=191, Percent_Identity=29.3193717277487, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI170784867, Length=200, Percent_Identity=25.5, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI42476022, Length=138, Percent_Identity=23.1884057971014, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI301898023, Length=138, Percent_Identity=23.1884057971014, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI296531396, Length=199, Percent_Identity=23.1155778894472, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI224809432, Length=195, Percent_Identity=26.1538461538462, Blast_Score=66, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=193, Percent_Identity=28.4974093264249, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI115532692, Length=193, Percent_Identity=28.4974093264249, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25147174, Length=174, Percent_Identity=26.4367816091954, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17647755, Length=183, Percent_Identity=31.6939890710383, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24585827, Length=183, Percent_Identity=31.6939890710383, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24585829, Length=183, Percent_Identity=31.6939890710383, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24647123, Length=198, Percent_Identity=25.2525252525253, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 52203; Mature: 52203

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIKGNRVKELRNFFCNQSLIISRKKIGWKIWGFRPNDNYFEKGYKGFTLSLLRLVSTL
CCCCCCCHHHHHHHHHCCCCCEEEHHHCCEEEEEECCCCCHHHCCCCHHHHHHHHHHHHH
ILTVIVSMSDSIAYGQNQSFDNYQKRKSLIFLSQNQEQVEDFKLREEIRDGVREEVDYTF
HHHHHHHCCCCCCCCCCCCCHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
RHAMSLLSVFLIVLTFFPASAAVWIWFLQAKLAHKVDVTKQEIDSFKYDTVSQLKQIIVD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHH
TQVILDELRVESGKAEEKIEQLQQDTLIQFSSEQGDNSEPLMMAKDYAKKADTFFFSGQF
HHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCCCCCCEEHHHHHHHHHCCEEECCHH
KEAINAYNQALKIHPKMADVWNNRGVALTRLKIFDEAISSYDRALQIRADYADAWNNRGV
HHHHHHHHHHHCCCCHHHHHHCCCCEEEHHHHHHHHHHHHHHHHEEEEECHHHHCCCCCE
CLIELQHYQEAINSFEQGIKVKPDYADAWNNRGVCLAKIQKYQEAVKSYNQAIAIKNDYG
EEEEHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCC
DAWNNRGACLMKLGIYGEAIACFDNAVKIQPDFFSAWYNQARCYSLKGDVDMALKSFEKA
CCCCCCCCEEEEECCCCCHHHHCCCCEEECCHHHHHHHCCCEEEEECCCHHHHHHHHHHH
VSLNGKKSQKMAKNEPDFDNIRDHELFQKLIV
HCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MKIIKGNRVKELRNFFCNQSLIISRKKIGWKIWGFRPNDNYFEKGYKGFTLSLLRLVSTL
CCCCCCCHHHHHHHHHCCCCCEEEHHHCCEEEEEECCCCCHHHCCCCHHHHHHHHHHHHH
ILTVIVSMSDSIAYGQNQSFDNYQKRKSLIFLSQNQEQVEDFKLREEIRDGVREEVDYTF
HHHHHHHCCCCCCCCCCCCCHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
RHAMSLLSVFLIVLTFFPASAAVWIWFLQAKLAHKVDVTKQEIDSFKYDTVSQLKQIIVD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHH
TQVILDELRVESGKAEEKIEQLQQDTLIQFSSEQGDNSEPLMMAKDYAKKADTFFFSGQF
HHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCCCCCCCEEHHHHHHHHHCCEEECCHH
KEAINAYNQALKIHPKMADVWNNRGVALTRLKIFDEAISSYDRALQIRADYADAWNNRGV
HHHHHHHHHHHCCCCHHHHHHCCCCEEEHHHHHHHHHHHHHHHHEEEEECHHHHCCCCCE
CLIELQHYQEAINSFEQGIKVKPDYADAWNNRGVCLAKIQKYQEAVKSYNQAIAIKNDYG
EEEEHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCC
DAWNNRGACLMKLGIYGEAIACFDNAVKIQPDFFSAWYNQARCYSLKGDVDMALKSFEKA
CCCCCCCCEEEEECCCCCHHHHCCCCEEECCHHHHHHHCCCEEEEECCCHHHHHHHHHHH
VSLNGKKSQKMAKNEPDFDNIRDHELFQKLIV
HCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]