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The map label for this gene is rpiA

Identifier: 113476144

GI number: 113476144

Start: 3899425

End: 3900138

Strand: Direct

Name: rpiA

Synonym: Tery_2528

Alternate gene names: 113476144

Gene position: 3899425-3900138 (Clockwise)

Preceding gene: 113476142

Following gene: 113476145

Centisome position: 50.31

GC content: 38.94

Gene sequence:

>714_bases
ATGGTAACAGAACAAGACCCGACCACGTTAATGAAACAGCAAGTCGGCAAAGCTGCTGCTGAGGAAGTAAAATCTGGTAT
GATAGTAGGTTTAGGCACAGGTTCAACTACTGCCTACATGATTCAATTTTTAGGAGAACTCCTCCAAAGAGGTGAACTCA
AAGATATCAAAGGTATCCCTACCTCCTTCCAGTCAACCGTATTAGCTAAAAAGTATGGTGTACCATTAACAACCCTTGAT
GAAGTTGATTATATGGATATTGCCATTGATGGGGCAGATGAAGTTGACCCACAAAAAAATCTGATTAAAGGTGGTGGAGC
CGCTCATACTCGTGAGAAAATTGTAGACTGTTTAGCAGAAAAGTTTGTTGTCGTAGTAGATAGTTCTAAACTAGTAGATA
AATTGGGTTCTACTTTTTTATTGCCCGTAGAAGTTATACCCATGGCAATGAATCCTGTAATTCGGGCGATCGAAAAATTG
GGTGGTCAACCAGAAGTACGGATGGGAGTGAAAAAGGCCGGACCTATAGTCACAGATCAAGGTAATTTGGTTATTGATGT
CAAGTTTGATTCCATTGATAACCCTGGGGAGCTAGAAAAAAGTTTAAATAATATTCCTGGAGTTTTGGAAAATGGCTTAT
TTGTAGGGGTTGCAGATGTAATTTTAGTAGGAGAAATTGACAATGGAAAACCAATAGTTAGGACAATTTCTTAA

Upstream 100 bases:

>100_bases
ATATTTATAGTAATAGACCAAAAGCATACTTAACTTTAACCTGCAAAATAGCTTAGATAAATTAGGTAGTGCTGATAATT
CGATCTGGAGTATTAAAGTT

Downstream 100 bases:

>100_bases
CAAAAAATATTGAGCCAGACTCTAGAAAATCATATCAACTCTAGGAAGAACAACCGAAGTTTAAAAATTATTGGCAAACC
TTTTCCAAGTTGCCAATATA

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MVTEQDPTTLMKQQVGKAAAEEVKSGMIVGLGTGSTTAYMIQFLGELLQRGELKDIKGIPTSFQSTVLAKKYGVPLTTLD
EVDYMDIAIDGADEVDPQKNLIKGGGAAHTREKIVDCLAEKFVVVVDSSKLVDKLGSTFLLPVEVIPMAMNPVIRAIEKL
GGQPEVRMGVKKAGPIVTDQGNLVIDVKFDSIDNPGELEKSLNNIPGVLENGLFVGVADVILVGEIDNGKPIVRTIS

Sequences:

>Translated_237_residues
MVTEQDPTTLMKQQVGKAAAEEVKSGMIVGLGTGSTTAYMIQFLGELLQRGELKDIKGIPTSFQSTVLAKKYGVPLTTLD
EVDYMDIAIDGADEVDPQKNLIKGGGAAHTREKIVDCLAEKFVVVVDSSKLVDKLGSTFLLPVEVIPMAMNPVIRAIEKL
GGQPEVRMGVKKAGPIVTDQGNLVIDVKFDSIDNPGELEKSLNNIPGVLENGLFVGVADVILVGEIDNGKPIVRTIS
>Mature_237_residues
MVTEQDPTTLMKQQVGKAAAEEVKSGMIVGLGTGSTTAYMIQFLGELLQRGELKDIKGIPTSFQSTVLAKKYGVPLTTLD
EVDYMDIAIDGADEVDPQKNLIKGGGAAHTREKIVDCLAEKFVVVVDSSKLVDKLGSTFLLPVEVIPMAMNPVIRAIEKL
GGQPEVRMGVKKAGPIVTDQGNLVIDVKFDSIDNPGELEKSLNNIPGVLENGLFVGVADVILVGEIDNGKPIVRTIS

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=230, Percent_Identity=43.0434782608696, Blast_Score=178, Evalue=3e-45,
Organism=Escherichia coli, GI1789280, Length=225, Percent_Identity=47.1111111111111, Blast_Score=172, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17551758, Length=231, Percent_Identity=39.8268398268398, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324669, Length=210, Percent_Identity=37.1428571428571, Blast_Score=121, Evalue=8e-29,
Organism=Drosophila melanogaster, GI281364072, Length=203, Percent_Identity=43.3497536945813, Blast_Score=152, Evalue=2e-37,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_TRIEI (Q111U2)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_722205.1
- ProteinModelPortal:   Q111U2
- SMR:   Q111U2
- STRING:   Q111U2
- GeneID:   4245063
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_2528
- NMPDR:   fig|203124.1.peg.13
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   DKSIVGV
- PhylomeDB:   Q111U2
- ProtClustDB:   PRK00702
- BioCyc:   TERY203124:TERY_2528-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 25274; Mature: 25274

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTEQDPTTLMKQQVGKAAAEEVKSGMIVGLGTGSTTAYMIQFLGELLQRGELKDIKGIP
CCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCC
TSFQSTVLAKKYGVPLTTLDEVDYMDIAIDGADEVDPQKNLIKGGGAAHTREKIVDCLAE
CHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHCCCCCCHHHHHHHHHHHH
KFVVVVDSSKLVDKLGSTFLLPVEVIPMAMNPVIRAIEKLGGQPEVRMGVKKAGPIVTDQ
CEEEEECCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHCCCEEECC
GNLVIDVKFDSIDNPGELEKSLNNIPGVLENGLFVGVADVILVGEIDNGKPIVRTIS
CCEEEEEEECCCCCHHHHHHHHHHCCHHHHCCEEEEEEEEEEEEECCCCCCEEEECC
>Mature Secondary Structure
MVTEQDPTTLMKQQVGKAAAEEVKSGMIVGLGTGSTTAYMIQFLGELLQRGELKDIKGIP
CCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCC
TSFQSTVLAKKYGVPLTTLDEVDYMDIAIDGADEVDPQKNLIKGGGAAHTREKIVDCLAE
CHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHCCCCCCHHHHHHHHHHHH
KFVVVVDSSKLVDKLGSTFLLPVEVIPMAMNPVIRAIEKLGGQPEVRMGVKKAGPIVTDQ
CEEEEECCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHCCCEEECC
GNLVIDVKFDSIDNPGELEKSLNNIPGVLENGLFVGVADVILVGEIDNGKPIVRTIS
CCEEEEEEECCCCCHHHHHHHHHHCCHHHHCCEEEEEEEEEEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA