Click here to switch to the map view.

The map label for this gene is ndhB

Identifier: 113476145

GI number: 113476145

Start: 3901498

End: 3903078

Strand: Direct

Name: ndhB

Synonym: Tery_2529

Alternate gene names: 113476145

Gene position: 3901498-3903078 (Clockwise)

Preceding gene: 113476144

Following gene: 113476149

Centisome position: 50.34

GC content: 38.58

Gene sequence:

>1581_bases
ATGATAGATTTATCTACCATTGCAGCTCAACTTAATGCCCGCACCATTCTCCCAGAAGGAATAGTCGTGATCACCCTGCT
GGTAGTTCTCGTCGGAGACCTAATACTGGGGCGTAGTTCTACTAAATGGACTCCTTATGCCGCCATTGTTGGTCTCTTAG
GAGCAATTGTAGCCTTATATACTCAATGGGATAGTAGCAATACCATAGGTTTTTTAGGAGCCTTTAATGCCGATGCCCTG
AGTATAGCATTTAGAGGCATTATTGCTATATCAGCGATTACTACTATATTAATGTCAGTAGCATACATAGAACAAACTGG
AACTCCACTAGGAGAATTTATCTGTATTCTGCTAACCGCTACCTTGGGAGCAATGTTCCTATCTGGAGCAGATGAGTTGG
TAATGATTTTCATTTCTCTAGAAACTCTAAGTATCTCCTCTTATTTATTAACCGGTTATACAAAACGTGATCCTCGTTCT
AATGAAGCAGCATTAAAATATTTACTCATAGGAGCCGCTAGCTCCGCAATTTTTCTTTATGGCATTTCCCTGCTTTATGG
TTTATCCGGTGGAGAAACCAGGTTAACAGCGATCGCTTCTAGTATGGCAAATGCTGGTAGTGCTAATATTTCACTAGCCC
TCGTCATTGCCTTAGTATTTGCTATTGCAGGTATTTCTTTCAAAATTTCTGCTGTTCCTTTTCATCAATGGACTCCAGAT
GTTTACGAAGGTTCTCCTACTCCAGTTGTGGCCTTTCTTTCAGTGGGTTCTAAAGCAGCAGGTTTTGCCCTAGCCATTCG
TCTTTTAGTAACAGCTTTCCCATTAGTTTCAGAACAATGGCATTTTGTATTTACTGCCCTAGCTATTCTAAGTATGGTAT
TAGGTAATGTAGTTGCTCTTGCCCAAACCAGCATGAAACGTCTACTTGCTTACTCATCTATTGGACAAGCTGGTTTTGTG
ATGATCGGTCTTTTGGCCAATACGGAAGCAGGTTACGCTAGCATGATATTTTATCTGCTGGTTTATTTATTTATGAACTT
GGGTGGTTTTACCTGTGTGATTTTATTTTCTCTACGTACAGGTACAGACCAAATTAGTGAATATGCAGGTCTATACCAAA
AAGACCCACTGTTAACATTAGGATTAAGTCTTTGTTTGTTGTCTTTAGGTGGTATACCACCACTTGCAGGTTTCTTTGGT
AAAATTTATCTGTTTTGGGCAGGCTGGCAAGCTGGATTATATTGGTTAGTTTTATTAGGATTAATTACCAGTGTGGCTTC
TATTTACTATTACATTCGTGTGGTTAAAATGATGGTAGTAAAAGAACCACAAGAAATGTCTGATGTAATTAAAAATTATC
CTCCCATTAGCTGGAAACTCCCTGGTATGCGTCCTTTACAAGTAGGATTAATTTTGTCAGTTCTAGCAACATCTTTAGCT
GGAATTTTATCTAACCCTTTATTTACTTTAGCTAATAGTTCTATTGCTAAAACTCCTATGTTAAATTCAGCTTTAGTCAA
GACTGTTGAAGCTAATTCAGTAGCCAGTCAACTAGATTTTTCTTTGCCGTCAAAGAACTAG

Upstream 100 bases:

>100_bases
AAACCAAAAAATATCTAGATCCAGGGTAAAATCCTCTACTGTAAAGGATTATGAATCATCCAAAATTCTTAATTACACAA
AAAATTTCAAATTATTTAAC

Downstream 100 bases:

>100_bases
TTGAAGTTGTTTGGAGTAAATAAACTAAGTTCAGAACGAGAAATGTTCGACTTAATTTTAGTCGAGCATTTTTTATTTAC
CTAGTTTTAATTGAGCAATT

Product: NAD(P)H-quinone oxidoreductase subunit 2

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase subunit 2; NADH-plastoquinone oxidoreductase subunit 2; NDH-1, subunit 2

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MIDLSTIAAQLNARTILPEGIVVITLLVVLVGDLILGRSSTKWTPYAAIVGLLGAIVALYTQWDSSNTIGFLGAFNADAL
SIAFRGIIAISAITTILMSVAYIEQTGTPLGEFICILLTATLGAMFLSGADELVMIFISLETLSISSYLLTGYTKRDPRS
NEAALKYLLIGAASSAIFLYGISLLYGLSGGETRLTAIASSMANAGSANISLALVIALVFAIAGISFKISAVPFHQWTPD
VYEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFPLVSEQWHFVFTALAILSMVLGNVVALAQTSMKRLLAYSSIGQAGFV
MIGLLANTEAGYASMIFYLLVYLFMNLGGFTCVILFSLRTGTDQISEYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFG
KIYLFWAGWQAGLYWLVLLGLITSVASIYYYIRVVKMMVVKEPQEMSDVIKNYPPISWKLPGMRPLQVGLILSVLATSLA
GILSNPLFTLANSSIAKTPMLNSALVKTVEANSVASQLDFSLPSKN

Sequences:

>Translated_526_residues
MIDLSTIAAQLNARTILPEGIVVITLLVVLVGDLILGRSSTKWTPYAAIVGLLGAIVALYTQWDSSNTIGFLGAFNADAL
SIAFRGIIAISAITTILMSVAYIEQTGTPLGEFICILLTATLGAMFLSGADELVMIFISLETLSISSYLLTGYTKRDPRS
NEAALKYLLIGAASSAIFLYGISLLYGLSGGETRLTAIASSMANAGSANISLALVIALVFAIAGISFKISAVPFHQWTPD
VYEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFPLVSEQWHFVFTALAILSMVLGNVVALAQTSMKRLLAYSSIGQAGFV
MIGLLANTEAGYASMIFYLLVYLFMNLGGFTCVILFSLRTGTDQISEYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFG
KIYLFWAGWQAGLYWLVLLGLITSVASIYYYIRVVKMMVVKEPQEMSDVIKNYPPISWKLPGMRPLQVGLILSVLATSLA
GILSNPLFTLANSSIAKTPMLNSALVKTVEANSVASQLDFSLPSKN
>Mature_526_residues
MIDLSTIAAQLNARTILPEGIVVITLLVVLVGDLILGRSSTKWTPYAAIVGLLGAIVALYTQWDSSNTIGFLGAFNADAL
SIAFRGIIAISAITTILMSVAYIEQTGTPLGEFICILLTATLGAMFLSGADELVMIFISLETLSISSYLLTGYTKRDPRS
NEAALKYLLIGAASSAIFLYGISLLYGLSGGETRLTAIASSMANAGSANISLALVIALVFAIAGISFKISAVPFHQWTPD
VYEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFPLVSEQWHFVFTALAILSMVLGNVVALAQTSMKRLLAYSSIGQAGFV
MIGLLANTEAGYASMIFYLLVYLFMNLGGFTCVILFSLRTGTDQISEYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFG
KIYLFWAGWQAGLYWLVLLGLITSVASIYYYIRVVKMMVVKEPQEMSDVIKNYPPISWKLPGMRPLQVGLILSVLATSLA
GILSNPLFTLANSSIAKTPMLNSALVKTVEANSVASQLDFSLPSKN

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Homo sapiens, GI251831117, Length=403, Percent_Identity=23.5732009925558, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI251831108, Length=208, Percent_Identity=27.8846153846154, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI145693160, Length=451, Percent_Identity=34.1463414634146, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1788829, Length=347, Percent_Identity=29.1066282420749, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788614, Length=324, Percent_Identity=25.3086419753086, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1788831, Length=290, Percent_Identity=25.1724137931034, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788827, Length=332, Percent_Identity=25, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788613, Length=366, Percent_Identity=24.0437158469945, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NU2C_TRIEI (Q111U1)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_722206.1
- STRING:   Q111U1
- GeneID:   4245064
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_2529
- NMPDR:   fig|203124.1.peg.12
- eggNOG:   COG1007
- HOGENOM:   HBG747830
- OMA:   FAGWADH
- PhylomeDB:   Q111U1
- ProtClustDB:   PRK02504
- BioCyc:   TERY203124:TERY_2529-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: 1.6.5.3

Molecular weight: Translated: 56003; Mature: 56003

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x18941ba0)-; HASH(0x17825814)-; HASH(0x16a8b534)-; HASH(0x17825904)-; HASH(0x19064f48)-; HASH(0x170c89d8)-; HASH(0x170c8bf4)-; HASH(0x170c8c84)-; HASH(0x153fe778)-; HASH(0x183625d0)-; HASH(0x19044c1c)-; HASH(0x1906177c)-; HASH(0x190262f4)-; HASH(0x19061950)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLSTIAAQLNARTILPEGIVVITLLVVLVGDLILGRSSTKWTPYAAIVGLLGAIVALY
CCCHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
TQWDSSNTIGFLGAFNADALSIAFRGIIAISAITTILMSVAYIEQTGTPLGEFICILLTA
HHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TLGAMFLSGADELVMIFISLETLSISSYLLTGYTKRDPRSNEAALKYLLIGAASSAIFLY
HHHHHHHCCCCCEEEEEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHHHH
GISLLYGLSGGETRLTAIASSMANAGSANISLALVIALVFAIAGISFKISAVPFHQWTPD
HHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
VYEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFPLVSEQWHFVFTALAILSMVLGNVVAL
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AQTSMKRLLAYSSIGQAGFVMIGLLANTEAGYASMIFYLLVYLFMNLGGFTCVILFSLRT
HHHHHHHHHHHHCCCCCHHHEEEEHHCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHCC
GTDQISEYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYWLVLLG
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECHHHHHHHHHHHH
LITSVASIYYYIRVVKMMVVKEPQEMSDVIKNYPPISWKLPGMRPLQVGLILSVLATSLA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHH
GILSNPLFTLANSSIAKTPMLNSALVKTVEANSVASQLDFSLPSKN
HHHCCCHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCH
>Mature Secondary Structure
MIDLSTIAAQLNARTILPEGIVVITLLVVLVGDLILGRSSTKWTPYAAIVGLLGAIVALY
CCCHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
TQWDSSNTIGFLGAFNADALSIAFRGIIAISAITTILMSVAYIEQTGTPLGEFICILLTA
HHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TLGAMFLSGADELVMIFISLETLSISSYLLTGYTKRDPRSNEAALKYLLIGAASSAIFLY
HHHHHHHCCCCCEEEEEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHHHH
GISLLYGLSGGETRLTAIASSMANAGSANISLALVIALVFAIAGISFKISAVPFHQWTPD
HHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
VYEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFPLVSEQWHFVFTALAILSMVLGNVVAL
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AQTSMKRLLAYSSIGQAGFVMIGLLANTEAGYASMIFYLLVYLFMNLGGFTCVILFSLRT
HHHHHHHHHHHHCCCCCHHHEEEEHHCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHCC
GTDQISEYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYWLVLLG
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECHHHHHHHHHHHH
LITSVASIYYYIRVVKMMVVKEPQEMSDVIKNYPPISWKLPGMRPLQVGLILSVLATSLA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHH
GILSNPLFTLANSSIAKTPMLNSALVKTVEANSVASQLDFSLPSKN
HHHCCCHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA