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The map label for this gene is cobH [H]

Identifier: 113475353

GI number: 113475353

Start: 2541678

End: 2542307

Strand: Direct

Name: cobH [H]

Synonym: Tery_1670

Alternate gene names: 113475353

Gene position: 2541678-2542307 (Clockwise)

Preceding gene: 113475352

Following gene: 113475355

Centisome position: 32.8

GC content: 43.49

Gene sequence:

>630_bases
ATGATTGATTACATTCGCAACGGAAAAGAAATTTACCGCAAATCTTTTGCAATGATTCGCTCTGAAGTAAACCTAGAGTT
CTTGCCTATTGATTTAGCTGATATGGCAGTCAGGCTAATTCACGCTTGTGGGATGACAGATATTCTTGAAGACCTAGTAA
CTTCACTGGATGCAGTAAAAATAGGTTGCGCTGCATTACAAAAAGGCGCACCCATCCTCTGTGATACTCAAATGGTAGCA
AATGGAATTATTCGTCATCGCTTGCCTGCCAATAACAAAGTTATTTGCACCCTCAATTATCCAGAAGTGCCAGAAAGGGC
ACAACAAATTAACAATACTCGCTCGGCGACTGCTATAGAATTATGGAAACCTCTGATTCATGGTTCCGTTGTAGCTATTG
GCAATGCACCAACCGCATTGTTTCACTTACTAGAATTATTAGATGAGGGAATGGCAAAACCTGCCCTAATTTTAGGTTTT
CCTGTAGGTTTTGTGGGTGCAGCAGAGTCAAAAGTAGAGCTGGCAACCAATAGTCGGGGTGTTCCATTTATCACGCTGCA
TGGACGACGGGGAGGCAGTGCCATAGCTGCTGCCGCCGTTAATGCCCTAGCAAAGGAAAGCGAGGTATAA

Upstream 100 bases:

>100_bases
TCTCATTAATGAGCCATAATAAACTAGTTACCTTTAGCCATGTTTAGATGATTCTTGACTCGTATGCCATCTTTTTAAAT
TTTAGACTAAATTTTACTAA

Downstream 100 bases:

>100_bases
CATTTATACCAAGGACTCGGAATGTTTGTTACATCCAGTAGGGATGTTCCATGGAACGAACCTAGGTCATATCATGTCTG
CCTAGATACTTAAGGCTTGC

Product: precorrin-8X methylmutase

Products: NA

Alternate protein names: HBA synthase; Precorrin isomerase [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MIDYIRNGKEIYRKSFAMIRSEVNLEFLPIDLADMAVRLIHACGMTDILEDLVTSLDAVKIGCAALQKGAPILCDTQMVA
NGIIRHRLPANNKVICTLNYPEVPERAQQINNTRSATAIELWKPLIHGSVVAIGNAPTALFHLLELLDEGMAKPALILGF
PVGFVGAAESKVELATNSRGVPFITLHGRRGGSAIAAAAVNALAKESEV

Sequences:

>Translated_209_residues
MIDYIRNGKEIYRKSFAMIRSEVNLEFLPIDLADMAVRLIHACGMTDILEDLVTSLDAVKIGCAALQKGAPILCDTQMVA
NGIIRHRLPANNKVICTLNYPEVPERAQQINNTRSATAIELWKPLIHGSVVAIGNAPTALFHLLELLDEGMAKPALILGF
PVGFVGAAESKVELATNSRGVPFITLHGRRGGSAIAAAAVNALAKESEV
>Mature_209_residues
MIDYIRNGKEIYRKSFAMIRSEVNLEFLPIDLADMAVRLIHACGMTDILEDLVTSLDAVKIGCAALQKGAPILCDTQMVA
NGIIRHRLPANNKVICTLNYPEVPERAQQINNTRSATAIELWKPLIHGSVVAIGNAPTALFHLLELLDEGMAKPALILGF
PVGFVGAAESKVELATNSRGVPFITLHGRRGGSAIAAAAVNALAKESEV

Specific function: Catalyzes the conversion of precorrin-8X to hydrogenobyrinic acid; a methyl migration reaction during the transformation of precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: =5.4.1.2 [H]

Molecular weight: Translated: 22452; Mature: 22452

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDYIRNGKEIYRKSFAMIRSEVNLEFLPIDLADMAVRLIHACGMTDILEDLVTSLDAVK
CCCCHHCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IGCAALQKGAPILCDTQMVANGIIRHRLPANNKVICTLNYPEVPERAQQINNTRSATAIE
HHHHHHHCCCCEEECHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHCCCCCHHHHH
LWKPLIHGSVVAIGNAPTALFHLLELLDEGMAKPALILGFPVGFVGAAESKVELATNSRG
HHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCHHCCCCCCEEEEECCCCC
VPFITLHGRRGGSAIAAAAVNALAKESEV
CEEEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDYIRNGKEIYRKSFAMIRSEVNLEFLPIDLADMAVRLIHACGMTDILEDLVTSLDAVK
CCCCHHCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IGCAALQKGAPILCDTQMVANGIIRHRLPANNKVICTLNYPEVPERAQQINNTRSATAIE
HHHHHHHCCCCEEECHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHCCCCCHHHHH
LWKPLIHGSVVAIGNAPTALFHLLELLDEGMAKPALILGFPVGFVGAAESKVELATNSRG
HHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCHHCCCCCCEEEEECCCCC
VPFITLHGRRGGSAIAAAAVNALAKESEV
CEEEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732194 [H]