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The map label for this gene is mhpC [C]

Identifier: 113474614

GI number: 113474614

Start: 1247396

End: 1248022

Strand: Direct

Name: mhpC [C]

Synonym: Tery_0781

Alternate gene names: 113474614

Gene position: 1247396-1248022 (Clockwise)

Preceding gene: 113474613

Following gene: 113474615

Centisome position: 16.1

GC content: 33.49

Gene sequence:

>627_bases
ATGTCTAAATCAATCATGGATACCAATATTAATTATAAATGTCTGGAGTTGGAAAATGCTCGGATCCATTACCTAGAAAC
TGGAAAAAAAAATGCAGTTAGTGTATTGTTGCTACATGGAGCAAGTTTTACTGCTCATACATGGCAAGAAATAGGTACTC
TTGATATTTTGACTACCCAGGGTTACCGAGCTGTTGCAGTAGATATTCCTGGCTATGGTCGTTCCCAAAGAATATCAGTT
TCTAACTTAGGTTTTTTGCGAGGAATATTAAATAAGTTAAACTTAAATTTACCAATTTTAGTATCCCCTTCTATGAGCGG
TGGTTATAGTTTCCCTTTTGTGATTGATGATTTTGATAAACTAGGGGGCTTTGTAGCAGTTTCCACTGTAGGAATTGAGC
GTTTTCAGGATGAATTAAAAGGAATTAAATTACCAACATTAGCTATTTGGGGAAGTAATGATCGGATAGTACCTATAGAA
AAAGCTGATTTATTAGTAGAATTAATGCCCAATGCTCAAAAAGTTATTCTGACTGACGCTGGTCATGCTTGTTATATACA
AAAAACTGAAGAGTTTCACAAACATTTAATTAAATTTATTAAGAGCATTGACTTCATTAAAGAATAA

Upstream 100 bases:

>100_bases
GCTAATTTATAGAAAACTATTTTATTTTTATGTAAAATTTATGTTGGCAATATTCATGTTTAATAATCAGTTTTTATTGT
ACTATTTAAAATTATAAAAT

Downstream 100 bases:

>100_bases
TATGAAGTGGACTGACACAGGGCATACTAGAAACTAAATTTCTATATGTAATTTCTAGTAATTTATAGCACCCTAAGTAA
AGATATGGACATTTATAGGA

Product: abhydrolase

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: Alpha/Beta Hydrolase Fold Protein; Abhydrolase; Alpha/Beta Hydrolase Fold; Alpha/Beta Fold Family Hydrolase; Carboxylesterase; 2-Hydroxy-6-Oxo-6-Phenylhexa-2 4-Dienoate Hydrolase; Hydrolase Or Acyltransferase; Alpha/Beta Superfamily Hydrolase/Acyltransferase

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MSKSIMDTNINYKCLELENARIHYLETGKKNAVSVLLLHGASFTAHTWQEIGTLDILTTQGYRAVAVDIPGYGRSQRISV
SNLGFLRGILNKLNLNLPILVSPSMSGGYSFPFVIDDFDKLGGFVAVSTVGIERFQDELKGIKLPTLAIWGSNDRIVPIE
KADLLVELMPNAQKVILTDAGHACYIQKTEEFHKHLIKFIKSIDFIKE

Sequences:

>Translated_208_residues
MSKSIMDTNINYKCLELENARIHYLETGKKNAVSVLLLHGASFTAHTWQEIGTLDILTTQGYRAVAVDIPGYGRSQRISV
SNLGFLRGILNKLNLNLPILVSPSMSGGYSFPFVIDDFDKLGGFVAVSTVGIERFQDELKGIKLPTLAIWGSNDRIVPIE
KADLLVELMPNAQKVILTDAGHACYIQKTEEFHKHLIKFIKSIDFIKE
>Mature_207_residues
SKSIMDTNINYKCLELENARIHYLETGKKNAVSVLLLHGASFTAHTWQEIGTLDILTTQGYRAVAVDIPGYGRSQRISVS
NLGFLRGILNKLNLNLPILVSPSMSGGYSFPFVIDDFDKLGGFVAVSTVGIERFQDELKGIKLPTLAIWGSNDRIVPIEK
ADLLVELMPNAQKVILTDAGHACYIQKTEEFHKHLIKFIKSIDFIKE

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI226437571, Length=194, Percent_Identity=37.1134020618557, Blast_Score=134, Evalue=6e-32,
Organism=Homo sapiens, GI226443152, Length=180, Percent_Identity=36.1111111111111, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI14249382, Length=180, Percent_Identity=36.1111111111111, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17543658, Length=175, Percent_Identity=29.1428571428571, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.7.1.- [C]

Molecular weight: Translated: 23165; Mature: 23034

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSIMDTNINYKCLELENARIHYLETGKKNAVSVLLLHGASFTAHTWQEIGTLDILTTQ
CCCCEEECCCCEEEEEECCCEEEEEECCCCCCEEEEEEECCCCCHHHHHHCCEEEEEECC
GYRAVAVDIPGYGRSQRISVSNLGFLRGILNKLNLNLPILVSPSMSGGYSFPFVIDDFDK
CCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHCCCCCEEECCCCCCCEECCEEEECHHH
LGGFVAVSTVGIERFQDELKGIKLPTLAIWGSNDRIVPIEKADLLVELMPNAQKVILTDA
CCCEEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEHHHHEEEEECCCCEEEEEEEC
GHACYIQKTEEFHKHLIKFIKSIDFIKE
CCEEEEECHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKSIMDTNINYKCLELENARIHYLETGKKNAVSVLLLHGASFTAHTWQEIGTLDILTTQ
CCCEEECCCCEEEEEECCCEEEEEECCCCCCEEEEEEECCCCCHHHHHHCCEEEEEECC
GYRAVAVDIPGYGRSQRISVSNLGFLRGILNKLNLNLPILVSPSMSGGYSFPFVIDDFDK
CCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHCCCCCEEECCCCCCCEECCEEEECHHH
LGGFVAVSTVGIERFQDELKGIKLPTLAIWGSNDRIVPIEKADLLVELMPNAQKVILTDA
CCCEEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEHHHHEEEEECCCCEEEEEEEC
GHACYIQKTEEFHKHLIKFIKSIDFIKE
CCEEEEECHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA