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The map label for this gene is dnaN [H]

Identifier: 113473946

GI number: 113473946

Start: 10371

End: 10973

Strand: Direct

Name: dnaN [H]

Synonym: Tery_0008

Alternate gene names: 113473946

Gene position: 10371-10973 (Clockwise)

Preceding gene: 113473943

Following gene: 113473948

Centisome position: 0.13

GC content: 34.66

Gene sequence:

>603_bases
ATGCAGGAGGGTGAGGAAGAAATAGAGGAAGTTACAGAAATAGAAGAGTTTGAAGTAACAATTCCGGCGAAAGCTTTAAG
AGAGGTTGAACGTATGATTAGTATGGGTAAGTCTGGTTCTTCTGTGACATTAAAGTTTGATGAAAATCAGGTTATTTTTG
AGTTGGGAAAGCAGCGTTTAACTAGCCGAAAATTAGAAGGCCAATATCCTGCTTACCAACAATTGTTACCTAATCAGTTT
ACTAATCAAATTAATGTAGATCGAAAAAAATTTTTAGGAGCTGTGGAAAGAATTGCTGTTTTAGCTGACCAAAAGAATAA
TATCTTGAAGTGTACTATTGATAGTGTTAATCAAGAAATTTCTTTATCTGTAGATGCTCAAGATGTGGGAAGTGGTCGAG
AATCTATGGCAGCACAAATCTCTAGTGATGAGCCAGAAGAAATTGCTTTTAATGTGAAATATTTGATTGAAGGATTAAAG
GCTATTCCCTCAGCTTCTGAAATTTCTATTCAGTTAAATACTGCTACAACTCCAGTAGTTTTAAATCCTTTGGGAGGATT
TCAAATGACTTATTTAATTATGCCTGTCCAGTTAAGATCTTAG

Upstream 100 bases:

>100_bases
TAGGAGAGGAGCCGTGTGAGGTGAAAGTCTCACGCACGGTTTTGAAGACGAGTTGGGTAGGGTAATTTACCTGGCTTAGT
TTAACCAGACAGAAAGTGTA

Downstream 100 bases:

>100_bases
AGGGTAAAGTTTTCATTATATATTTTTTGGTGGGTTGAAGTATTTTATATGCTTGAAACTGCTAAATTTGAGATTGTTAT
TATCTCATTGAATTTGTTTA

Product: DNA polymerase III subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MQEGEEEIEEVTEIEEFEVTIPAKALREVERMISMGKSGSSVTLKFDENQVIFELGKQRLTSRKLEGQYPAYQQLLPNQF
TNQINVDRKKFLGAVERIAVLADQKNNILKCTIDSVNQEISLSVDAQDVGSGRESMAAQISSDEPEEIAFNVKYLIEGLK
AIPSASEISIQLNTATTPVVLNPLGGFQMTYLIMPVQLRS

Sequences:

>Translated_200_residues
MQEGEEEIEEVTEIEEFEVTIPAKALREVERMISMGKSGSSVTLKFDENQVIFELGKQRLTSRKLEGQYPAYQQLLPNQF
TNQINVDRKKFLGAVERIAVLADQKNNILKCTIDSVNQEISLSVDAQDVGSGRESMAAQISSDEPEEIAFNVKYLIEGLK
AIPSASEISIQLNTATTPVVLNPLGGFQMTYLIMPVQLRS
>Mature_200_residues
MQEGEEEIEEVTEIEEFEVTIPAKALREVERMISMGKSGSSVTLKFDENQVIFELGKQRLTSRKLEGQYPAYQQLLPNQF
TNQINVDRKKFLGAVERIAVLADQKNNILKCTIDSVNQEISLSVDAQDVGSGRESMAAQISSDEPEEIAFNVKYLIEGLK
AIPSASEISIQLNTATTPVVLNPLGGFQMTYLIMPVQLRS

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped

COG id: COG0592

COG function: function code L; DNA polymerase sliding clamp subunit (PCNA homolog)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 5954 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001001
- InterPro:   IPR022635
- InterPro:   IPR022637
- InterPro:   IPR022634 [H]

Pfam domain/function: PF00712 DNA_pol3_beta; PF02767 DNA_pol3_beta_2; PF02768 DNA_pol3_beta_3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 22270; Mature: 22270

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEGEEEIEEVTEIEEFEVTIPAKALREVERMISMGKSGSSVTLKFDENQVIFELGKQRL
CCCCHHHHHHHHHHHHEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHH
TSRKLEGQYPAYQQLLPNQFTNQINVDRKKFLGAVERIAVLADQKNNILKCTIDSVNQEI
HHHHCCCCCCHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEE
SLSVDAQDVGSGRESMAAQISSDEPEEIAFNVKYLIEGLKAIPSASEISIQLNTATTPVV
EEEECHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEE
LNPLGGFQMTYLIMPVQLRS
ECCCCCCEEEEEEEEEEECC
>Mature Secondary Structure
MQEGEEEIEEVTEIEEFEVTIPAKALREVERMISMGKSGSSVTLKFDENQVIFELGKQRL
CCCCHHHHHHHHHHHHEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHH
TSRKLEGQYPAYQQLLPNQFTNQINVDRKKFLGAVERIAVLADQKNNILKCTIDSVNQEI
HHHHCCCCCCHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEE
SLSVDAQDVGSGRESMAAQISSDEPEEIAFNVKYLIEGLKAIPSASEISIQLNTATTPVV
EEEECHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEE
LNPLGGFQMTYLIMPVQLRS
ECCCCCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8654968 [H]