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The map label for this gene is dnaA

Identifier: 113473943

GI number: 113473943

Start: 27

End: 1397

Strand: Direct

Name: dnaA

Synonym: Tery_0001

Alternate gene names: 113473943

Gene position: 27-1397 (Clockwise)

Preceding gene: NA

Following gene: 113473946

Centisome position: 0.0

GC content: 33.55

Gene sequence:

>1371_bases
GTGGAAATTTATCTAGATAATTTATGGGACCAAGTTTTAGAAAGGCTCCAATTACAGTTAAGTAAACCAACTTTTGAAAC
TTGGATTAAAACAGCAACTGCTGAACAATTAGAAAATAATTGTTTAGTAATTCGCGCCCCTAATCCTTTTGCTCGAAATT
GGTTACAGAAATACTATATAAAAACTATTGCTGACGTTGTACATGATATTTTAGGTTACCCAGTAGAAATTTATTTAACT
ACTTTTTTAGTTGAAGATAGTAGAAAAAATGACTCGGGACTCATTTGGTCTGAACATAAGTCCGTAAATATTCTGGGAGA
AAATTTATCTATTCCAAAACCATTACCAGCAAATCTTAATGCCAAATATATGTTTTCTCGGTTTGTAGTAGGTCCAAATA
ATCGTATGGCTCATGCCGCTTCTTTAGCAGTGGCAGAGTCTCCAGGACAAGAGTTTAATCCTTTATTTTTATGTGGTGGA
GTCGGTTTAGGTAAAACTCATTTAATGCAAGCTATTGGTCATTATCGTTTAGATATTTTTCCTCATTCTCAAATATTTTA
TGTTTCTACAGAAAAATTTACTAATGATTTGATTGCTGCTATTCGTAAAGATAGTCTGCAAGGCTTTAGAGAACATTATC
GAGCAGCAGACGTTTTATTAGTAGATGATATTCAATTTATTGAAGGTAAAGAATATACTCAGGAGGAATTTTTTCATACT
TTTAATACTTTGCATGAGGCTGGCAAACAAGTAGTCTTAGCTTCTGATAGACCTCCCAATCAAATTCCTAGTTTACAAGA
ACGTCTTTGCTCTCGGTTTTCTATGGGATTAATTGCAGATATTCAAGCTCCAGATCTGGAAACTAGAATGGCAATTTTAC
TAAAAAAGTCTGAGTATGAAAATATGGTTTTGCCTAGGGATGTAATTGAATATATTGCAACTAGATATCCTTCAAATATT
CGGGAGTTGGAGGGAGCTTTAACAAGGGTTGTTACTTATATTTCTATTTCTGGTTTGCCTATGACTGTGGAAAATATTGC
ACCTATTTTAAATCCAAAAACAGAAAAGTTAGAGGCTTCACCAGAGGCAGTTATTAAGGTTGTTTCCGAAAATTTTAACT
TATCTATAGAGGATTTGAAGGGTAGTTCTAGAAAGCGAGAAATTACTTTAGCAAGACAAGTTGGGATGTATTTGATGCGA
CAACATACTGATTTGAGTTTACCAAAAATTGGAGAGGTTTTTGGAGGAAAAGACCACACCACTGTTTTGTATAGTTGCGA
CAAAATTAGTCAGCTACAAAATAGTGACTTAAATTTAGTTCAAACAATTCGACAATTGAGCGATCGAATTAATTTTTCTA
GTCGTCATTAG

Upstream 100 bases:

>100_bases
AAAAAAATAACTTGTTTGGTAGTTCTGAAAAACAAACTTTTATTGAATAATTTATAAATTTAATTTGCTTTGTTTGTAGC
GATATAAAAAGAGGCTAGCA

Downstream 100 bases:

>100_bases
TTAGTATAAATAAGAAGGAGAAGATTAGGTAACTAACAGATCCATCCTTTAGGATTTTTAACATATGGTTATTTTCAATA
AGAATGAGGCACTATTTTGT

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MEIYLDNLWDQVLERLQLQLSKPTFETWIKTATAEQLENNCLVIRAPNPFARNWLQKYYIKTIADVVHDILGYPVEIYLT
TFLVEDSRKNDSGLIWSEHKSVNILGENLSIPKPLPANLNAKYMFSRFVVGPNNRMAHAASLAVAESPGQEFNPLFLCGG
VGLGKTHLMQAIGHYRLDIFPHSQIFYVSTEKFTNDLIAAIRKDSLQGFREHYRAADVLLVDDIQFIEGKEYTQEEFFHT
FNTLHEAGKQVVLASDRPPNQIPSLQERLCSRFSMGLIADIQAPDLETRMAILLKKSEYENMVLPRDVIEYIATRYPSNI
RELEGALTRVVTYISISGLPMTVENIAPILNPKTEKLEASPEAVIKVVSENFNLSIEDLKGSSRKREITLARQVGMYLMR
QHTDLSLPKIGEVFGGKDHTTVLYSCDKISQLQNSDLNLVQTIRQLSDRINFSSRH

Sequences:

>Translated_456_residues
MEIYLDNLWDQVLERLQLQLSKPTFETWIKTATAEQLENNCLVIRAPNPFARNWLQKYYIKTIADVVHDILGYPVEIYLT
TFLVEDSRKNDSGLIWSEHKSVNILGENLSIPKPLPANLNAKYMFSRFVVGPNNRMAHAASLAVAESPGQEFNPLFLCGG
VGLGKTHLMQAIGHYRLDIFPHSQIFYVSTEKFTNDLIAAIRKDSLQGFREHYRAADVLLVDDIQFIEGKEYTQEEFFHT
FNTLHEAGKQVVLASDRPPNQIPSLQERLCSRFSMGLIADIQAPDLETRMAILLKKSEYENMVLPRDVIEYIATRYPSNI
RELEGALTRVVTYISISGLPMTVENIAPILNPKTEKLEASPEAVIKVVSENFNLSIEDLKGSSRKREITLARQVGMYLMR
QHTDLSLPKIGEVFGGKDHTTVLYSCDKISQLQNSDLNLVQTIRQLSDRINFSSRH
>Mature_456_residues
MEIYLDNLWDQVLERLQLQLSKPTFETWIKTATAEQLENNCLVIRAPNPFARNWLQKYYIKTIADVVHDILGYPVEIYLT
TFLVEDSRKNDSGLIWSEHKSVNILGENLSIPKPLPANLNAKYMFSRFVVGPNNRMAHAASLAVAESPGQEFNPLFLCGG
VGLGKTHLMQAIGHYRLDIFPHSQIFYVSTEKFTNDLIAAIRKDSLQGFREHYRAADVLLVDDIQFIEGKEYTQEEFFHT
FNTLHEAGKQVVLASDRPPNQIPSLQERLCSRFSMGLIADIQAPDLETRMAILLKKSEYENMVLPRDVIEYIATRYPSNI
RELEGALTRVVTYISISGLPMTVENIAPILNPKTEKLEASPEAVIKVVSENFNLSIEDLKGSSRKREITLARQVGMYLMR
QHTDLSLPKIGEVFGGKDHTTVLYSCDKISQLQNSDLNLVQTIRQLSDRINFSSRH

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family

Homologues:

Organism=Escherichia coli, GI2367267, Length=447, Percent_Identity=37.3601789709172, Blast_Score=316, Evalue=2e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNAA_TRIEI (Q11AE3)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_720004.1
- ProteinModelPortal:   Q11AE3
- STRING:   Q11AE3
- GeneID:   4242308
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_0001
- NMPDR:   fig|203124.1.peg.3918
- eggNOG:   COG0593
- HOGENOM:   HBG695666
- OMA:   QFIQNKE
- PhylomeDB:   Q11AE3
- ProtClustDB:   PRK00149
- BioCyc:   TERY203124:TERY_0001-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00377
- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1750.10
- PRINTS:   PR00051
- SMART:   SM00382
- SMART:   SM00760
- TIGRFAMs:   TIGR00362

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 51888; Mature: 51888

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIYLDNLWDQVLERLQLQLSKPTFETWIKTATAEQLENNCLVIRAPNPFARNWLQKYYI
CEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHH
KTIADVVHDILGYPVEIYLTTFLVEDSRKNDSGLIWSEHKSVNILGENLSIPKPLPANLN
HHHHHHHHHHHCCCHHHEEEEEEEECCCCCCCCCEEECCCCEEEEECCCCCCCCCCCCCC
AKYMFSRFVVGPNNRMAHAASLAVAESPGQEFNPLFLCGGVGLGKTHLMQAIGHYRLDIF
HHEEEEEEEECCCCCHHHHHHHHEECCCCCCCCCEEEECCCCCCHHHHHHHHCCCEEEEE
PHSQIFYVSTEKFTNDLIAAIRKDSLQGFREHYRAADVLLVDDIQFIEGKEYTQEEFFHT
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHCCCCHHHHHHHHH
FNTLHEAGKQVVLASDRPPNQIPSLQERLCSRFSMGLIADIQAPDLETRMAILLKKSEYE
HHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHEECCCCC
NMVLPRDVIEYIATRYPSNIRELEGALTRVVTYISISGLPMTVENIAPILNPKTEKLEAS
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEECCCCEEHHHHHHHCCCCCHHHCCC
PEAVIKVVSENFNLSIEDLKGSSRKREITLARQVGMYLMRQHTDLSLPKIGEVFGGKDHT
HHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCC
TVLYSCDKISQLQNSDLNLVQTIRQLSDRINFSSRH
EEEEECHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEIYLDNLWDQVLERLQLQLSKPTFETWIKTATAEQLENNCLVIRAPNPFARNWLQKYYI
CEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHH
KTIADVVHDILGYPVEIYLTTFLVEDSRKNDSGLIWSEHKSVNILGENLSIPKPLPANLN
HHHHHHHHHHHCCCHHHEEEEEEEECCCCCCCCCEEECCCCEEEEECCCCCCCCCCCCCC
AKYMFSRFVVGPNNRMAHAASLAVAESPGQEFNPLFLCGGVGLGKTHLMQAIGHYRLDIF
HHEEEEEEEECCCCCHHHHHHHHEECCCCCCCCCEEEECCCCCCHHHHHHHHCCCEEEEE
PHSQIFYVSTEKFTNDLIAAIRKDSLQGFREHYRAADVLLVDDIQFIEGKEYTQEEFFHT
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHCCCCHHHHHHHHH
FNTLHEAGKQVVLASDRPPNQIPSLQERLCSRFSMGLIADIQAPDLETRMAILLKKSEYE
HHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHEECCCCC
NMVLPRDVIEYIATRYPSNIRELEGALTRVVTYISISGLPMTVENIAPILNPKTEKLEAS
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEECCCCEEHHHHHHHCCCCCHHHCCC
PEAVIKVVSENFNLSIEDLKGSSRKREITLARQVGMYLMRQHTDLSLPKIGEVFGGKDHT
HHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCC
TVLYSCDKISQLQNSDLNLVQTIRQLSDRINFSSRH
EEEEECHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA