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The map label for this gene is ureC

Identifier: 110835580

GI number: 110835580

Start: 3075848

End: 3077551

Strand: Reverse

Name: ureC

Synonym: ABO_2719

Alternate gene names: 110835580

Gene position: 3077551-3075848 (Counterclockwise)

Preceding gene: 110835581

Following gene: 110835579

Centisome position: 98.63

GC content: 56.46

Gene sequence:

>1704_bases
GTGGCAACAATGTCCAGACAAGCCTACGCCGACATGTTCGGGCCCACCACAGGTGACCGGGTACGCCTGGCCGATACCGA
TCTGTGGATCCAGGTAGAAAAAGATTTCACCGTCTATGGTGACGAAGTGAAATTTGGCGGCGGCAAGGTAATTCGTGATG
GCATGGGCCAATCCCAGCTGCCTTCGGCGAAGGTTATGGACCTGGTCATTACCAATGCCTTGATCCTCGACTACTGGGGG
ATCGTTAAAGCGGATATCGGTATTAAGAACGGGCGAATTGCGGCCATTGGCAAGGCGGGTAACCCAGATGTGCAACCGAA
TGTGGATATCATTGTTGGCCCCGGCACCGATGTGATTGCTGGTGAAGGCAGCATCATTACGGCGGGGGGGATTGATTCGC
ATATCCATTTTATCTGCCCGCAGCAGATCGACGAAGCATTAGCATCCGGGGTCACCACCATGATCGGTGGCGGCACCGGG
CCCACCACCGGCACCAATGCCACCACAGTGACGCCCGGGCCCTGGAACATGGCCCGAATGTTGGAAGCGGCGGATTGCTT
TCCAATGAATCTGGGGTTCCTTGGCAAAGGTAACGCCAGCTTGCCGGAATCCCTGAGCGAACAGATCAGCGCCGGCGCCA
TTGGCCTGAAATTGCACGAAGACTGGGGCACCACCCCCGCCTCAATCGACAACTGCCTTTCGGTTGCAGAAGAAACGGAT
ACTCAAGTGGCGATCCACACCGACACCTTGAACGAATCCGGCTTTGTGGAAGACACCATCGCCGCGTTCAAAGATCGCAC
CATCCATACCTATCACACCGAGGGAGCCGGGGGCGGCCATGCGCCGGATATTATTCGCGCTGCTGGGCTTGCCAATGTGC
TGCCTTCGTCCACAAACCCGACGCGACCTTACACGGTGAATACCGCCGATGAGCACCTCGATATGCTCATGGTCTGTCAC
CATTTGGATCCGAGTATTCCAGAAGACGTAGCGTTTGCTGAATCCCGCATTCGCCGCGAAACCATTGCCGCGGAAGACAT
CCTTCATGATCTTGGTGCGTTCTCCATGATTGCCTCAGACTCCCAGGCCATGGGGCGTGTGGGCGAAGTGGTGATGCGCA
CCTGGCAAACGGCCCACAAGATGAAAGTGCAGCGCGGTTCCCTAAAGGGCGACCCATCCGAACATGATAATTTTCGCGCC
AAACGCTACGTAGCCAAGTACACCATCAACCCGGCATTAGCCCATGGCATGGCCCATGAAATAGGCTCGGTGGAAGTGGG
CAAGCTCGCCGACCTGGTACTGTGGAGCCCGGCCTTTTTTGGGGTAAAGCCCAACCTCATCATTAAGGGCGGCATGATCG
CCATGGCCAAGATGGGCGACCCTAACGCATCCATCCCTACACCCCAGCCAGTTCATTACCGCCCCATGTTTGGGGCCTAC
GGCAAGGCTCGCCAAGCCACCACCATGACCTTCATCTCCCAGGCCGCCATGGATGCGGGTATCCCTGAGCAACTCACATT
AGCCAACCGCATTGGTGTGGTGAAAGGCTGCCGCACAGTGAAAAAGAAAGACATGTTGCTCAATGATTGGCTGCCACACC
TGGAAGTGGATCCACAGACCTATGAAGTACGTGCCGATGGCCAGCTGCTAACGTGCGAACCGGCGGAAGTGTTGCCAATG
GCGCAGCGCTATTTTTTGTTTTAA

Upstream 100 bases:

>100_bases
GGAAATAGCGCCATGGGAAGCAGGCCGGCGCCTGTACAACACCGCATTTCGGAAAGGCTGCCGATAACCAGCCGGTAGAT
GCAAGAACAGGAGAATCATC

Downstream 100 bases:

>100_bases
CGCATTGTTTACGAGACAAGCATGATCGAACTGACGAAAAAAATTACCGATACCGTCGCGCTGGAAAAAATCGATCCGGC
GAGACTAAAAACCCTCAGCC

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MATMSRQAYADMFGPTTGDRVRLADTDLWIQVEKDFTVYGDEVKFGGGKVIRDGMGQSQLPSAKVMDLVITNALILDYWG
IVKADIGIKNGRIAAIGKAGNPDVQPNVDIIVGPGTDVIAGEGSIITAGGIDSHIHFICPQQIDEALASGVTTMIGGGTG
PTTGTNATTVTPGPWNMARMLEAADCFPMNLGFLGKGNASLPESLSEQISAGAIGLKLHEDWGTTPASIDNCLSVAEETD
TQVAIHTDTLNESGFVEDTIAAFKDRTIHTYHTEGAGGGHAPDIIRAAGLANVLPSSTNPTRPYTVNTADEHLDMLMVCH
HLDPSIPEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQAMGRVGEVVMRTWQTAHKMKVQRGSLKGDPSEHDNFRA
KRYVAKYTINPALAHGMAHEIGSVEVGKLADLVLWSPAFFGVKPNLIIKGGMIAMAKMGDPNASIPTPQPVHYRPMFGAY
GKARQATTMTFISQAAMDAGIPEQLTLANRIGVVKGCRTVKKKDMLLNDWLPHLEVDPQTYEVRADGQLLTCEPAEVLPM
AQRYFLF

Sequences:

>Translated_567_residues
MATMSRQAYADMFGPTTGDRVRLADTDLWIQVEKDFTVYGDEVKFGGGKVIRDGMGQSQLPSAKVMDLVITNALILDYWG
IVKADIGIKNGRIAAIGKAGNPDVQPNVDIIVGPGTDVIAGEGSIITAGGIDSHIHFICPQQIDEALASGVTTMIGGGTG
PTTGTNATTVTPGPWNMARMLEAADCFPMNLGFLGKGNASLPESLSEQISAGAIGLKLHEDWGTTPASIDNCLSVAEETD
TQVAIHTDTLNESGFVEDTIAAFKDRTIHTYHTEGAGGGHAPDIIRAAGLANVLPSSTNPTRPYTVNTADEHLDMLMVCH
HLDPSIPEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQAMGRVGEVVMRTWQTAHKMKVQRGSLKGDPSEHDNFRA
KRYVAKYTINPALAHGMAHEIGSVEVGKLADLVLWSPAFFGVKPNLIIKGGMIAMAKMGDPNASIPTPQPVHYRPMFGAY
GKARQATTMTFISQAAMDAGIPEQLTLANRIGVVKGCRTVKKKDMLLNDWLPHLEVDPQTYEVRADGQLLTCEPAEVLPM
AQRYFLF
>Mature_566_residues
ATMSRQAYADMFGPTTGDRVRLADTDLWIQVEKDFTVYGDEVKFGGGKVIRDGMGQSQLPSAKVMDLVITNALILDYWGI
VKADIGIKNGRIAAIGKAGNPDVQPNVDIIVGPGTDVIAGEGSIITAGGIDSHIHFICPQQIDEALASGVTTMIGGGTGP
TTGTNATTVTPGPWNMARMLEAADCFPMNLGFLGKGNASLPESLSEQISAGAIGLKLHEDWGTTPASIDNCLSVAEETDT
QVAIHTDTLNESGFVEDTIAAFKDRTIHTYHTEGAGGGHAPDIIRAAGLANVLPSSTNPTRPYTVNTADEHLDMLMVCHH
LDPSIPEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQAMGRVGEVVMRTWQTAHKMKVQRGSLKGDPSEHDNFRAK
RYVAKYTINPALAHGMAHEIGSVEVGKLADLVLWSPAFFGVKPNLIIKGGMIAMAKMGDPNASIPTPQPVHYRPMFGAYG
KARQATTMTFISQAAMDAGIPEQLTLANRIGVVKGCRTVKKKDMLLNDWLPHLEVDPQTYEVRADGQLLTCEPAEVLPMA
QRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE1_ALCBS (Q0VKY1)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_694439.1
- ProteinModelPortal:   Q0VKY1
- SMR:   Q0VKY1
- STRING:   Q0VKY1
- GeneID:   4211733
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2719
- NMPDR:   fig|393595.12.peg.2728
- eggNOG:   COG0804
- HOGENOM:   HBG357507
- OMA:   TIHAFHT
- ProtClustDB:   PRK13207
- BioCyc:   ABOR393595:ABO_2719-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01953
- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950
- PRINTS:   PR01752
- TIGRFAMs:   TIGR01792

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha; SSF51338 Metalo_hydrolase

EC number: =3.5.1.5

Molecular weight: Translated: 60863; Mature: 60732

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS01120 UREASE_1; PS00145 UREASE_2; PS51368 UREASE_3

Important sites: ACT_SITE 320-320 BINDING 219-219

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATMSRQAYADMFGPTTGDRVRLADTDLWIQVEKDFTVYGDEVKFGGGKVIRDGMGQSQL
CCCCCHHHHHHHCCCCCCCEEEEECCEEEEEEECCEEEECCEEEECCCEEEECCCCCCCC
PSAKVMDLVITNALILDYWGIVKADIGIKNGRIAAIGKAGNPDVQPNVDIIVGPGTDVIA
CCHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCEEE
GEGSIITAGGIDSHIHFICPQQIDEALASGVTTMIGGGTGPTTGTNATTVTPGPWNMARM
CCCCEEEECCCCCCEEEECHHHHHHHHHCCCCEEECCCCCCCCCCCCEEECCCCCHHHHH
LEAADCFPMNLGFLGKGNASLPESLSEQISAGAIGLKLHEDWGTTPASIDNCLSVAEETD
HHHCCCCCCCCCEECCCCCCCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCC
TQVAIHTDTLNESGFVEDTIAAFKDRTIHTYHTEGAGGGHAPDIIRAAGLANVLPSSTNP
CEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCC
TRPYTVNTADEHLDMLMVCHHLDPSIPEDVAFAESRIRRETIAAEDILHDLGAFSMIASD
CCCEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SQAMGRVGEVVMRTWQTAHKMKVQRGSLKGDPSEHDNFRAKRYVAKYTINPALAHGMAHE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEEEECCHHHHHHHHHH
IGSVEVGKLADLVLWSPAFFGVKPNLIIKGGMIAMAKMGDPNASIPTPQPVHYRPMFGAY
CCCEEHHHHHHHHEECCHHCCCCCCEEEECCEEEEEECCCCCCCCCCCCCCEECCCCCCC
GKARQATTMTFISQAAMDAGIPEQLTLANRIGVVKGCRTVKKKDMLLNDWLPHLEVDPQT
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
YEVRADGQLLTCEPAEVLPMAQRYFLF
EEEEECCEEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure 
ATMSRQAYADMFGPTTGDRVRLADTDLWIQVEKDFTVYGDEVKFGGGKVIRDGMGQSQL
CCCCHHHHHHHCCCCCCCEEEEECCEEEEEEECCEEEECCEEEECCCEEEECCCCCCCC
PSAKVMDLVITNALILDYWGIVKADIGIKNGRIAAIGKAGNPDVQPNVDIIVGPGTDVIA
CCHHHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCEEE
GEGSIITAGGIDSHIHFICPQQIDEALASGVTTMIGGGTGPTTGTNATTVTPGPWNMARM
CCCCEEEECCCCCCEEEECHHHHHHHHHCCCCEEECCCCCCCCCCCCEEECCCCCHHHHH
LEAADCFPMNLGFLGKGNASLPESLSEQISAGAIGLKLHEDWGTTPASIDNCLSVAEETD
HHHCCCCCCCCCEECCCCCCCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCC
TQVAIHTDTLNESGFVEDTIAAFKDRTIHTYHTEGAGGGHAPDIIRAAGLANVLPSSTNP
CEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCC
TRPYTVNTADEHLDMLMVCHHLDPSIPEDVAFAESRIRRETIAAEDILHDLGAFSMIASD
CCCEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SQAMGRVGEVVMRTWQTAHKMKVQRGSLKGDPSEHDNFRAKRYVAKYTINPALAHGMAHE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEEEECCHHHHHHHHHH
IGSVEVGKLADLVLWSPAFFGVKPNLIIKGGMIAMAKMGDPNASIPTPQPVHYRPMFGAY
CCCEEHHHHHHHHEECCHHCCCCCCEEEECCEEEEEECCCCCCCCCCCCCCEECCCCCCC
GKARQATTMTFISQAAMDAGIPEQLTLANRIGVVKGCRTVKKKDMLLNDWLPHLEVDPQT
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
YEVRADGQLLTCEPAEVLPMAQRYFLF
EEEEECCEEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA