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The map label for this gene is livM [H]

Identifier: 110835372

GI number: 110835372

Start: 2848191

End: 2849351

Strand: Direct

Name: livM [H]

Synonym: ABO_2511

Alternate gene names: 110835372

Gene position: 2848191-2849351 (Clockwise)

Preceding gene: 110835371

Following gene: 110835373

Centisome position: 91.28

GC content: 56.68

Gene sequence:

>1161_bases
ATGCGAGATTCAACATTCAAAAGCGCCTTCAGCGACCGCGCAGCAAAAACCTTTATGGGCGTGCTGTTTGGTGCCACCCT
GCTGGTGACCATACTCAACCAGCTGTTTCCAGCTGACTCTGCCCTGCATGTAAGCGCCTACACCGTGACGCTGCTTGGCA
AATACCTGTGTTACGCGCTGCTGGCGCTGGCGCTGGATCTCGTGTGGGGCTACTGCGGTATTCTCAGCCTGGGCCACGGC
GCCTTCTTTGCCTTGGGAGGCTATGCCATGGGCATGTACCTGATGCGCCAGATCGGCGATCGCGGCGTCTATGGCAACCC
GGACCTCCCTGACTTCATGGTCTTTTTGAACTGGAGTGAGCTGCCCTGGTATTGGCAGGGTTTTGACCAATTTTGGTTTG
CCGCATTGATGATTCTGCTAGTGCCCGGTCTGCTGGCATTCGTATTCGGCTGGCTGGCGTTCCGCTCTAGAGTCACAGGG
GTCTACCTGTCCATCATCACCCAGGCGCTGACCTATGCGTTAATGCTGGCGTTCTTCCGTAACGAGTTGGGTTTTGGCGG
CAACAACGGGCTCACCGACTTCAAGGATTTGCTCGGCTTTTCCCTGCAATCGGATTCCACTCGCGTGGGCTTGTTGATGG
CCACCGCCGTAGCCCTGGCCGGTGCCTTTGTACTATGCCGCTGGATCACCGGCAGCAAACTGGGCCGCGTGGTACTGGCG
GTGCGTGATGCAGAATCCCGAGCGCGCTTTGTGGGTTACCGCACTGAACATTACAAACTGTGGATTTTCACCCTCAGCGC
CATCCTCGCGGGTATCGCCGGGGCGCTGTATGTGCCCCAGGTGGGCATCATTAATCCTGGAGAGTTCTCACCACTGAATT
CCATCGAGCTGGTGGTATGGGTGGCCGTTGGCGGTCGCGCCACCCTATATGGGGCGGTTATCGGCGCCATCTTGGTGAAC
TACGGTAAAACCGTATTCACCGGCATCATGCCCGAAGCCTGGCTGTTCGCCTTGGGGGGGCTGTTTGTAGCCGTTACCGT
ATTCCTTCCCCATGGATTAGTGGGTTTGGTATCGGAAAATTGGGAAAAAATAAAAGCGCGATTGAATCGAAACAACAAAC
CATCCGGCTCCGCCAGACCTGCAGAAGGAGACCTGTCATGA

Upstream 100 bases:

>100_bases
GTACTGGCCAAGATTGTGGTGCTGGTCTTCATCATTCTGTTTATACAGCGCAAACCGCGGGGTCTGTTCCCGCAACGTGG
CCGGGCGGCGGAGGAATAAC

Downstream 100 bases:

>100_bases
ATGCACTGGATAACCTGCGCGAGACTTTTCGCCGTGATCAGGTATTCGATTTCATGCGCCAAGGCACCCGCCCAGTGCTC
CCAGGGCAACTGGATTCTGG

Product: branched-chain amino acid ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein M [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MRDSTFKSAFSDRAAKTFMGVLFGATLLVTILNQLFPADSALHVSAYTVTLLGKYLCYALLALALDLVWGYCGILSLGHG
AFFALGGYAMGMYLMRQIGDRGVYGNPDLPDFMVFLNWSELPWYWQGFDQFWFAALMILLVPGLLAFVFGWLAFRSRVTG
VYLSIITQALTYALMLAFFRNELGFGGNNGLTDFKDLLGFSLQSDSTRVGLLMATAVALAGAFVLCRWITGSKLGRVVLA
VRDAESRARFVGYRTEHYKLWIFTLSAILAGIAGALYVPQVGIINPGEFSPLNSIELVVWVAVGGRATLYGAVIGAILVN
YGKTVFTGIMPEAWLFALGGLFVAVTVFLPHGLVGLVSENWEKIKARLNRNNKPSGSARPAEGDLS

Sequences:

>Translated_386_residues
MRDSTFKSAFSDRAAKTFMGVLFGATLLVTILNQLFPADSALHVSAYTVTLLGKYLCYALLALALDLVWGYCGILSLGHG
AFFALGGYAMGMYLMRQIGDRGVYGNPDLPDFMVFLNWSELPWYWQGFDQFWFAALMILLVPGLLAFVFGWLAFRSRVTG
VYLSIITQALTYALMLAFFRNELGFGGNNGLTDFKDLLGFSLQSDSTRVGLLMATAVALAGAFVLCRWITGSKLGRVVLA
VRDAESRARFVGYRTEHYKLWIFTLSAILAGIAGALYVPQVGIINPGEFSPLNSIELVVWVAVGGRATLYGAVIGAILVN
YGKTVFTGIMPEAWLFALGGLFVAVTVFLPHGLVGLVSENWEKIKARLNRNNKPSGSARPAEGDLS
>Mature_386_residues
MRDSTFKSAFSDRAAKTFMGVLFGATLLVTILNQLFPADSALHVSAYTVTLLGKYLCYALLALALDLVWGYCGILSLGHG
AFFALGGYAMGMYLMRQIGDRGVYGNPDLPDFMVFLNWSELPWYWQGFDQFWFAALMILLVPGLLAFVFGWLAFRSRVTG
VYLSIITQALTYALMLAFFRNELGFGGNNGLTDFKDLLGFSLQSDSTRVGLLMATAVALAGAFVLCRWITGSKLGRVVLA
VRDAESRARFVGYRTEHYKLWIFTLSAILAGIAGALYVPQVGIINPGEFSPLNSIELVVWVAVGGRATLYGAVIGAILVN
YGKTVFTGIMPEAWLFALGGLFVAVTVFLPHGLVGLVSENWEKIKARLNRNNKPSGSARPAEGDLS

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=341, Percent_Identity=23.7536656891496, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 42079; Mature: 42079

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDSTFKSAFSDRAAKTFMGVLFGATLLVTILNQLFPADSALHVSAYTVTLLGKYLCYAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LALALDLVWGYCGILSLGHGAFFALGGYAMGMYLMRQIGDRGVYGNPDLPDFMVFLNWSE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCC
LPWYWQGFDQFWFAALMILLVPGLLAFVFGWLAFRSRVTGVYLSIITQALTYALMLAFFR
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NELGFGGNNGLTDFKDLLGFSLQSDSTRVGLLMATAVALAGAFVLCRWITGSKLGRVVLA
HHCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
VRDAESRARFVGYRTEHYKLWIFTLSAILAGIAGALYVPQVGIINPGEFSPLNSIELVVW
EECCHHHHHHHCEECCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
VAVGGRATLYGAVIGAILVNYGKTVFTGIMPEAWLFALGGLFVAVTVFLPHGLVGLVSEN
EEECCCHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
WEKIKARLNRNNKPSGSARPAEGDLS
HHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRDSTFKSAFSDRAAKTFMGVLFGATLLVTILNQLFPADSALHVSAYTVTLLGKYLCYAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LALALDLVWGYCGILSLGHGAFFALGGYAMGMYLMRQIGDRGVYGNPDLPDFMVFLNWSE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCC
LPWYWQGFDQFWFAALMILLVPGLLAFVFGWLAFRSRVTGVYLSIITQALTYALMLAFFR
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NELGFGGNNGLTDFKDLLGFSLQSDSTRVGLLMATAVALAGAFVLCRWITGSKLGRVVLA
HHCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
VRDAESRARFVGYRTEHYKLWIFTLSAILAGIAGALYVPQVGIINPGEFSPLNSIELVVW
EECCHHHHHHHCEECCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
VAVGGRATLYGAVIGAILVNYGKTVFTGIMPEAWLFALGGLFVAVTVFLPHGLVGLVSEN
EEECCCHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
WEKIKARLNRNNKPSGSARPAEGDLS
HHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]