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The map label for this gene is glnA [H]

Identifier: 110835123

GI number: 110835123

Start: 2581577

End: 2582983

Strand: Reverse

Name: glnA [H]

Synonym: ABO_2262

Alternate gene names: 110835123

Gene position: 2582983-2581577 (Counterclockwise)

Preceding gene: 110835124

Following gene: 110835122

Centisome position: 82.78

GC content: 53.94

Gene sequence:

>1407_bases
ATGTCTGTTAAGACCCTCAAACTGATCAAAGAAAACGATGTGAAATGGGTGGACCTGCGCTTCACCGATAGCTCTGGTAA
GGAGCAGCACGTTACCCTTCCGGTTGGCGAAATCGACGAAGATTTCTTCCAGGACGGCAAAATGTTTGATGGCTCCTCCA
TCGCTGGTTGGAAGGGCATCAACGAATCGGACATGGTGATGATGCCGGACGACGAGTCCGCCGTGCTGGACCCGTTCACT
GACGTTGCTACCCTGAACTTGCGCTGCGACATTCTTGAGCCGACCACCATGCAAGGTTACGAGCGCGACCCGCGTTCCGT
TGCCCGTCGTGCTGAGGAATACCTGAAATCTACTGGTATCGCGGATACCGCTCTGTTCGGCCCTGAGCCGGAGTTTTTCG
TATTTGACTCCGTGCAGTGGAAGTCCGACATGCAGGGTTCCATGTATAACATCCACTCTGAAGAAGCTGCGTGGGTTTCC
CATGAAGACTTTGAGGGCGGCAACATTGGTCACCGTCCTGGTGTGAAAGGCGGTTACTTTCCGGTTCCTCCGGTAGACAG
CCTGCACGATCTGCGTGGCGCCATGTGTTCTGCCATGGAGTCCATGGGGCTGAAAATTGAAGTGCATCACCACGAAGTGG
GCACGGCTGGTCAGTGTGAGATCGGTGTTGGCGCCAACACCCTGACCGCCAAAGCGGACGAAGTACAGATTCTTAAGTAC
TGCGTACACAATGTGGCTCACGCTTACGGCAAGACAGCTACTTTCATGCCTAAGCCGCTGATCGGTGATAACGGCTCTGG
TATGCACGTGCACGTATCCCTGGGTAAAGACGGCAAAAACCTGTTCGCCGGTGACGGCTATGCTGGTCTGTCTGATGAAG
CGTTGTATTTCATTGGCGGTATCATTAAGCATGCCCGTGCGCTGAACGCATTCACCAATGCGTCCACTAACGCTTACAAG
CGTCTGGTGCCCGGTTTTGAAGCGCCGGTAATGTTGGCCTACTCTGCCCGTAACCGTTCTGCATCTATCCGCATCCCGTT
TGTGAACAGTGCTAAGGCCCGTCGTGTGGAAGCGCGCTTCCCTGACCCGTCTGCCAACCCGTACCTGTGCTTTGCTTCCC
TGCTGATGGCTGGCTTGGACGGCATCAAGAACAAGATGCACCCTGGCGATGCCATGGACAAAGATTTGTATGATTTGCCG
GCTGAAGAAGCAAAAGACATTCCTACCGTGGCTCACACTTTGACCATGGCCTTGGATTGTCTGGAAGAAGACATGGACTT
CCTGACCGAAGGTGACGTGTTCACCAAGGATATGCTGGAAGGCTACATCGAGCTGAAGCGTGCCGAGGTTGAGCGTCTGA
ACATGACCCCGCACCCGGTTGAGTTTGATATGTACTACTCTTGCTAA

Upstream 100 bases:

>100_bases
GGCCCAGTGGCCGAGAATACCGGTTCTTTGTGTTGCGCTTCCTCAGAGCGGCACGACGAGTCAGAGACAAACCCGCTGTT
CCTTAGGAGGACGCACGATA

Downstream 100 bases:

>100_bases
TGCCTTCGGGTCGCTAGCAGAACAGAGCCTCCGCTTGTCGGGGGCTTTTTTTTGCCTGGAATAAAGGCGGCGGTTTTGTG
CACTCCCCCCTTTTCTGAGC

Product: glutamine synthetase, type I

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSVKTLKLIKENDVKWVDLRFTDSSGKEQHVTLPVGEIDEDFFQDGKMFDGSSIAGWKGINESDMVMMPDDESAVLDPFT
DVATLNLRCDILEPTTMQGYERDPRSVARRAEEYLKSTGIADTALFGPEPEFFVFDSVQWKSDMQGSMYNIHSEEAAWVS
HEDFEGGNIGHRPGVKGGYFPVPPVDSLHDLRGAMCSAMESMGLKIEVHHHEVGTAGQCEIGVGANTLTAKADEVQILKY
CVHNVAHAYGKTATFMPKPLIGDNGSGMHVHVSLGKDGKNLFAGDGYAGLSDEALYFIGGIIKHARALNAFTNASTNAYK
RLVPGFEAPVMLAYSARNRSASIRIPFVNSAKARRVEARFPDPSANPYLCFASLLMAGLDGIKNKMHPGDAMDKDLYDLP
AEEAKDIPTVAHTLTMALDCLEEDMDFLTEGDVFTKDMLEGYIELKRAEVERLNMTPHPVEFDMYYSC

Sequences:

>Translated_468_residues
MSVKTLKLIKENDVKWVDLRFTDSSGKEQHVTLPVGEIDEDFFQDGKMFDGSSIAGWKGINESDMVMMPDDESAVLDPFT
DVATLNLRCDILEPTTMQGYERDPRSVARRAEEYLKSTGIADTALFGPEPEFFVFDSVQWKSDMQGSMYNIHSEEAAWVS
HEDFEGGNIGHRPGVKGGYFPVPPVDSLHDLRGAMCSAMESMGLKIEVHHHEVGTAGQCEIGVGANTLTAKADEVQILKY
CVHNVAHAYGKTATFMPKPLIGDNGSGMHVHVSLGKDGKNLFAGDGYAGLSDEALYFIGGIIKHARALNAFTNASTNAYK
RLVPGFEAPVMLAYSARNRSASIRIPFVNSAKARRVEARFPDPSANPYLCFASLLMAGLDGIKNKMHPGDAMDKDLYDLP
AEEAKDIPTVAHTLTMALDCLEEDMDFLTEGDVFTKDMLEGYIELKRAEVERLNMTPHPVEFDMYYSC
>Mature_467_residues
SVKTLKLIKENDVKWVDLRFTDSSGKEQHVTLPVGEIDEDFFQDGKMFDGSSIAGWKGINESDMVMMPDDESAVLDPFTD
VATLNLRCDILEPTTMQGYERDPRSVARRAEEYLKSTGIADTALFGPEPEFFVFDSVQWKSDMQGSMYNIHSEEAAWVSH
EDFEGGNIGHRPGVKGGYFPVPPVDSLHDLRGAMCSAMESMGLKIEVHHHEVGTAGQCEIGVGANTLTAKADEVQILKYC
VHNVAHAYGKTATFMPKPLIGDNGSGMHVHVSLGKDGKNLFAGDGYAGLSDEALYFIGGIIKHARALNAFTNASTNAYKR
LVPGFEAPVMLAYSARNRSASIRIPFVNSAKARRVEARFPDPSANPYLCFASLLMAGLDGIKNKMHPGDAMDKDLYDLPA
EEAKDIPTVAHTLTMALDCLEEDMDFLTEGDVFTKDMLEGYIELKRAEVERLNMTPHPVEFDMYYSC

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1790301, Length=464, Percent_Identity=67.6724137931034, Blast_Score=684, Evalue=0.0,
Organism=Escherichia coli, GI87081870, Length=175, Percent_Identity=30.2857142857143, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809
- InterPro:   IPR001637 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 51609; Mature: 51478

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP ; PS00182 GLNA_ADENYLATION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKTLKLIKENDVKWVDLRFTDSSGKEQHVTLPVGEIDEDFFQDGKMFDGSSIAGWKGI
CCCCEEEHEECCCCEEEEEEEECCCCCCEEEEECCCCCCHHHHHCCCEECCCCCCCCCCC
NESDMVMMPDDESAVLDPFTDVATLNLRCDILEPTTMQGYERDPRSVARRAEEYLKSTGI
CCCCEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
ADTALFGPEPEFFVFDSVQWKSDMQGSMYNIHSEEAAWVSHEDFEGGNIGHRPGVKGGYF
CHHHCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PVPPVDSLHDLRGAMCSAMESMGLKIEVHHHEVGTAGQCEIGVGANTLTAKADEVQILKY
CCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCCCEECCHHHHHHHHH
CVHNVAHAYGKTATFMPKPLIGDNGSGMHVHVSLGKDGKNLFAGDGYAGLSDEALYFIGG
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCHHHHHHH
IIKHARALNAFTNASTNAYKRLVPGFEAPVMLAYSARNRSASIRIPFVNSAKARRVEARF
HHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCEEECCC
PDPSANPYLCFASLLMAGLDGIKNKMHPGDAMDKDLYDLPAEEAKDIPTVAHTLTMALDC
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHCCCHHHHHHHHHHHH
LEEDMDFLTEGDVFTKDMLEGYIELKRAEVERLNMTPHPVEFDMYYSC
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
>Mature Secondary Structure 
SVKTLKLIKENDVKWVDLRFTDSSGKEQHVTLPVGEIDEDFFQDGKMFDGSSIAGWKGI
CCCEEEHEECCCCEEEEEEEECCCCCCEEEEECCCCCCHHHHHCCCEECCCCCCCCCCC
NESDMVMMPDDESAVLDPFTDVATLNLRCDILEPTTMQGYERDPRSVARRAEEYLKSTGI
CCCCEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
ADTALFGPEPEFFVFDSVQWKSDMQGSMYNIHSEEAAWVSHEDFEGGNIGHRPGVKGGYF
CHHHCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PVPPVDSLHDLRGAMCSAMESMGLKIEVHHHEVGTAGQCEIGVGANTLTAKADEVQILKY
CCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCCCEECCHHHHHHHHH
CVHNVAHAYGKTATFMPKPLIGDNGSGMHVHVSLGKDGKNLFAGDGYAGLSDEALYFIGG
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCCCHHHHHHH
IIKHARALNAFTNASTNAYKRLVPGFEAPVMLAYSARNRSASIRIPFVNSAKARRVEARF
HHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCEEECCC
PDPSANPYLCFASLLMAGLDGIKNKMHPGDAMDKDLYDLPAEEAKDIPTVAHTLTMALDC
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCHHHHHCCCHHHHHHHHHHHH
LEEDMDFLTEGDVFTKDMLEGYIELKRAEVERLNMTPHPVEFDMYYSC
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1969923 [H]