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The map label for this gene is rodA [H]

Identifier: 110834817

GI number: 110834817

Start: 2236421

End: 2237566

Strand: Direct

Name: rodA [H]

Synonym: ABO_1956

Alternate gene names: 110834817

Gene position: 2236421-2237566 (Clockwise)

Preceding gene: 110834816

Following gene: 110834818

Centisome position: 71.68

GC content: 56.28

Gene sequence:

>1146_bases
ATGAGCCAGCGCGAATTTACCCGCCAAATGCCAGGCCAAACCGGCGCTAGCCTATCACCCGGGCTGGCGGTACGCCTGCA
CCTGGATCCACCATTACTGGTGGGCCTGTTGCTACTCATGTTCGGGGGGCTCACCGTTCTTTATAGTGCTGGCGGGGAAA
GCATGGCGCTAGTGGTCCGTCAATGCATCCGCTTCGGCGCCGGCCTTATTGTGCTGTTTCTGTTGGCCCAAATCCCGCCG
CGAAGCTACCGCTTCTGGGCGCCAGTGATTTATTCCATCGGCCTGATGTTATTGATAATGGTGTTGCTCATCGGCACCGA
AGCCAAAGGGGCTCAACGCTGGTTATCCATTCCCGGCGCCGGCCGCTTCCAACCGGCGGAGGTGATGAAACTCGCGGTAC
CCGCCATGGTCGCCTGGTACTTCAGTGAACGCACGCTGCCCCCCCGGCTCACTGATGTGATTGCTGCCCTGCTATTACTC
GGCATTCCCGCCATGCTCATCGGCATGCAACCGGACCTGGGCACAGCCATTCTCATCGCGGCCAGTGGCTTGATAGTCCT
GTTCATGGCGGGGCTATCCTGGCGGCTGATTGCCGTGGCGATAATCATAGTGGTCACCGCCGCACCGCTGATGTATTTCT
TCGTGATGCATGATTATCAGCGCAACCGGGTAGACACTTTCCTTAATCCGGAAGCGGATCCGCGCGGTACCGGCTGGAAC
ATTATCCAGTCAAAAACCGCTATCGGTTCCGGGGGGGTTAACGGCAAAGGATGGCTAGACGGTACCCAATCACGCCTCGA
TTTCCTGCCGGAATCCTCCACCGACTTTATTCTCGCAGTGCTCAGCGAGGAATTCGGCCTAGTAGGCGTTATCGTATTGC
TGATGATGTACCTGGTCATCGTTGGCCGCGGTTTCTTTATTAGCTGGCACGCCCAAGACACGTTTGCCCGGCTACTGGCC
GCCAGCCTAGTGATGACATTTTTTATTTATGTTTTCGTGAACATTGGGATGGTTTCAGGGCTCTTACCTGTCGTAGGCGT
CCCTTTGCCTCTGGTCAGCTATGGCGGCACCTCCGTTGTCACGCTATTGGCCAGTTTTGGGATGTTGATGTCAATTCACA
CCCATCGGCGCCTAATGAGTTATTAA

Upstream 100 bases:

>100_bases
ATGAACAGGGGGAGCTGAAAGTACCGCCGGTGTTTGCCGAAACCCCGCCCCATCCACCGTCCAATACCACCATCAATAAT
GCCGGTAACGAGAACCGCCC

Downstream 100 bases:

>100_bases
ACGTGAAGCCGGCCCCCTAGTGCGCCGGTTTCCAACAAAACGCAGTCCATGGAAATAATGAAAACAGGAGAACCCCCTTT
GCGTCGTTTCTATCTAGGCA

Product: rod-shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MSQREFTRQMPGQTGASLSPGLAVRLHLDPPLLVGLLLLMFGGLTVLYSAGGESMALVVRQCIRFGAGLIVLFLLAQIPP
RSYRFWAPVIYSIGLMLLIMVLLIGTEAKGAQRWLSIPGAGRFQPAEVMKLAVPAMVAWYFSERTLPPRLTDVIAALLLL
GIPAMLIGMQPDLGTAILIAASGLIVLFMAGLSWRLIAVAIIIVVTAAPLMYFFVMHDYQRNRVDTFLNPEADPRGTGWN
IIQSKTAIGSGGVNGKGWLDGTQSRLDFLPESSTDFILAVLSEEFGLVGVIVLLMMYLVIVGRGFFISWHAQDTFARLLA
ASLVMTFFIYVFVNIGMVSGLLPVVGVPLPLVSYGGTSVVTLLASFGMLMSIHTHRRLMSY

Sequences:

>Translated_381_residues
MSQREFTRQMPGQTGASLSPGLAVRLHLDPPLLVGLLLLMFGGLTVLYSAGGESMALVVRQCIRFGAGLIVLFLLAQIPP
RSYRFWAPVIYSIGLMLLIMVLLIGTEAKGAQRWLSIPGAGRFQPAEVMKLAVPAMVAWYFSERTLPPRLTDVIAALLLL
GIPAMLIGMQPDLGTAILIAASGLIVLFMAGLSWRLIAVAIIIVVTAAPLMYFFVMHDYQRNRVDTFLNPEADPRGTGWN
IIQSKTAIGSGGVNGKGWLDGTQSRLDFLPESSTDFILAVLSEEFGLVGVIVLLMMYLVIVGRGFFISWHAQDTFARLLA
ASLVMTFFIYVFVNIGMVSGLLPVVGVPLPLVSYGGTSVVTLLASFGMLMSIHTHRRLMSY
>Mature_380_residues
SQREFTRQMPGQTGASLSPGLAVRLHLDPPLLVGLLLLMFGGLTVLYSAGGESMALVVRQCIRFGAGLIVLFLLAQIPPR
SYRFWAPVIYSIGLMLLIMVLLIGTEAKGAQRWLSIPGAGRFQPAEVMKLAVPAMVAWYFSERTLPPRLTDVIAALLLLG
IPAMLIGMQPDLGTAILIAASGLIVLFMAGLSWRLIAVAIIIVVTAAPLMYFFVMHDYQRNRVDTFLNPEADPRGTGWNI
IQSKTAIGSGGVNGKGWLDGTQSRLDFLPESSTDFILAVLSEEFGLVGVIVLLMMYLVIVGRGFFISWHAQDTFARLLAA
SLVMTFFIYVFVNIGMVSGLLPVVGVPLPLVSYGGTSVVTLLASFGMLMSIHTHRRLMSY

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=356, Percent_Identity=53.9325842696629, Blast_Score=367, Evalue=1e-103,
Organism=Escherichia coli, GI1786277, Length=331, Percent_Identity=34.7432024169184, Blast_Score=162, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41379; Mature: 41248

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQREFTRQMPGQTGASLSPGLAVRLHLDPPLLVGLLLLMFGGLTVLYSAGGESMALVVR
CCCHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHEEHHCCCCHHHHHHH
QCIRFGAGLIVLFLLAQIPPRSYRFWAPVIYSIGLMLLIMVLLIGTEAKGAQRWLSIPGA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCC
GRFQPAEVMKLAVPAMVAWYFSERTLPPRLTDVIAALLLLGIPAMLIGMQPDLGTAILIA
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ASGLIVLFMAGLSWRLIAVAIIIVVTAAPLMYFFVMHDYQRNRVDTFLNPEADPRGTGWN
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCH
IIQSKTAIGSGGVNGKGWLDGTQSRLDFLPESSTDFILAVLSEEFGLVGVIVLLMMYLVI
HHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
VGRGFFISWHAQDTFARLLAASLVMTFFIYVFVNIGMVSGLLPVVGVPLPLVSYGGTSVV
HCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHH
TLLASFGMLMSIHTHRRLMSY
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQREFTRQMPGQTGASLSPGLAVRLHLDPPLLVGLLLLMFGGLTVLYSAGGESMALVVR
CCHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHEEHHCCCCHHHHHHH
QCIRFGAGLIVLFLLAQIPPRSYRFWAPVIYSIGLMLLIMVLLIGTEAKGAQRWLSIPGA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCC
GRFQPAEVMKLAVPAMVAWYFSERTLPPRLTDVIAALLLLGIPAMLIGMQPDLGTAILIA
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ASGLIVLFMAGLSWRLIAVAIIIVVTAAPLMYFFVMHDYQRNRVDTFLNPEADPRGTGWN
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCH
IIQSKTAIGSGGVNGKGWLDGTQSRLDFLPESSTDFILAVLSEEFGLVGVIVLLMMYLVI
HHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
VGRGFFISWHAQDTFARLLAASLVMTFFIYVFVNIGMVSGLLPVVGVPLPLVSYGGTSVV
HCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHH
TLLASFGMLMSIHTHRRLMSY
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]