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The map label for this gene is mltB [H]

Identifier: 110834818

GI number: 110834818

Start: 2237615

End: 2238730

Strand: Direct

Name: mltB [H]

Synonym: ABO_1957

Alternate gene names: 110834818

Gene position: 2237615-2238730 (Clockwise)

Preceding gene: 110834817

Following gene: 110834819

Centisome position: 71.72

GC content: 54.39

Gene sequence:

>1116_bases
ATGGAAATAATGAAAACAGGAGAACCCCCTTTGCGTCGTTTCTATCTAGGCATTCTAAACATTTTCCGCTCCGGCACGGC
GTATTCAGCCATCGCGGTCGCAGCCCTGTTCTTCACCTCCCTGCCTGCCTTAGCCGAGCATACCTGCCCTGAAAACAACG
ACTATCTGCAGCGCAAACAAGTCCAAGCTCTAATAGCCGAGCTCGTCTCGCAAGGACAAGATGAGGCACGATTGCGAGAG
GTTCTGGGCAGCGCGCAATGCCAACCCCAGATTCTCAAATCCATTGCTCGCCCTGCAGAAAGAACCCATACCTGGGCCAC
TTATCAGAAAATTTTCCTACAGGAAAGCCGGGTTCAGAAAGGTATTGAATTCGCCCACACCCACGCCAAGACCTTGACCC
GCGCCGAACAAACCTACGGCGTACCGCGAGAAATTATTCTCGCCATCATTGGTGTGGAAACCCGCTACGGTGATCACATG
GGCAACTACCGTGTGGTCGATGCGCTGGCCACACTGGGCTATGACTACCCTCCCCGAGGAAGCTTCTTCCGCAAACAGCT
CAAAGCACTGTTTGAATTGGAACACCATGCCCATATTGACGCGAACACGATCACCGGCTCTTACGCGGGGGCCATGGGCT
ATGGCCAGTTTATCCCCACCAGTTACCAAGCCTACGCAGTGGATTTTGACAACGACGGTATCACCGATCTGGTCAATAAT
CCGGTGGATGCCATTGGCTCCGTGGCCAACTATTTCAGCGAACATAACTGGCAACCCGGTTTGCCCGTGGCTGCCAGAGC
TCGCTTACACGGTACCGGTTATGTCGCGCTGGCCAAGAAAGGTTACAAGCCATCCTTTACTCTGGCACAAGCCAACAGTG
CCGGCGTCACCGCACTCAGCTGCAACGACGATCGGCTGGTTAGTGAATACTGCTTTGATCTGCCCGCCAGCACCCGCGTC
GCCCTACTCGACCTGACCGGAACCGATGGCGCAGAATTTTGGCTGGCCACCGACAACTTTTATGTGATCACCCGCTACAA
TCACAGTCGCCTGTACGCCATGGCCGTGCTACAACTATCACGACAATTGGCTGCGGCACTGGAGGATAATCAATGA

Upstream 100 bases:

>100_bases
TTTTGGGATGTTGATGTCAATTCACACCCATCGGCGCCTAATGAGTTATTAAACGTGAAGCCGGCCCCCTAGTGCGCCGG
TTTCCAACAAAACGCAGTCC

Downstream 100 bases:

>100_bases
ACCGTTTGGCTTGCGCCGTACTGACCTCTGCCTTTCTCGGCGCCTGTGCCACAACGCCAGGGCCCAATGATGGCAATGAC
GGCCCAGGTGCCAGCAACGG

Product: membrane-bound lytic murein transglycosylase B

Products: Muramic Acid Residue [C]

Alternate protein names: 35 kDa soluble lytic transglycosylase; Murein hydrolase B; Slt35 [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MEIMKTGEPPLRRFYLGILNIFRSGTAYSAIAVAALFFTSLPALAEHTCPENNDYLQRKQVQALIAELVSQGQDEARLRE
VLGSAQCQPQILKSIARPAERTHTWATYQKIFLQESRVQKGIEFAHTHAKTLTRAEQTYGVPREIILAIIGVETRYGDHM
GNYRVVDALATLGYDYPPRGSFFRKQLKALFELEHHAHIDANTITGSYAGAMGYGQFIPTSYQAYAVDFDNDGITDLVNN
PVDAIGSVANYFSEHNWQPGLPVAARARLHGTGYVALAKKGYKPSFTLAQANSAGVTALSCNDDRLVSEYCFDLPASTRV
ALLDLTGTDGAEFWLATDNFYVITRYNHSRLYAMAVLQLSRQLAAALEDNQ

Sequences:

>Translated_371_residues
MEIMKTGEPPLRRFYLGILNIFRSGTAYSAIAVAALFFTSLPALAEHTCPENNDYLQRKQVQALIAELVSQGQDEARLRE
VLGSAQCQPQILKSIARPAERTHTWATYQKIFLQESRVQKGIEFAHTHAKTLTRAEQTYGVPREIILAIIGVETRYGDHM
GNYRVVDALATLGYDYPPRGSFFRKQLKALFELEHHAHIDANTITGSYAGAMGYGQFIPTSYQAYAVDFDNDGITDLVNN
PVDAIGSVANYFSEHNWQPGLPVAARARLHGTGYVALAKKGYKPSFTLAQANSAGVTALSCNDDRLVSEYCFDLPASTRV
ALLDLTGTDGAEFWLATDNFYVITRYNHSRLYAMAVLQLSRQLAAALEDNQ
>Mature_371_residues
MEIMKTGEPPLRRFYLGILNIFRSGTAYSAIAVAALFFTSLPALAEHTCPENNDYLQRKQVQALIAELVSQGQDEARLRE
VLGSAQCQPQILKSIARPAERTHTWATYQKIFLQESRVQKGIEFAHTHAKTLTRAEQTYGVPREIILAIIGVETRYGDHM
GNYRVVDALATLGYDYPPRGSFFRKQLKALFELEHHAHIDANTITGSYAGAMGYGQFIPTSYQAYAVDFDNDGITDLVNN
PVDAIGSVANYFSEHNWQPGLPVAARARLHGTGYVALAKKGYKPSFTLAQANSAGVTALSCNDDRLVSEYCFDLPASTRV
ALLDLTGTDGAEFWLATDNFYVITRYNHSRLYAMAVLQLSRQLAAALEDNQ

Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG2951

COG function: function code M; Membrane-bound lytic murein transglycosylase B

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789053, Length=323, Percent_Identity=39.3188854489164, Blast_Score=219, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011757 [H]

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 41143; Mature: 41143

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIMKTGEPPLRRFYLGILNIFRSGTAYSAIAVAALFFTSLPALAEHTCPENNDYLQRKQ
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VQALIAELVSQGQDEARLREVLGSAQCQPQILKSIARPAERTHTWATYQKIFLQESRVQK
HHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
GIEFAHTHAKTLTRAEQTYGVPREIILAIIGVETRYGDHMGNYRVVDALATLGYDYPPRG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHCCCCCCCC
SFFRKQLKALFELEHHAHIDANTITGSYAGAMGYGQFIPTSYQAYAVDFDNDGITDLVNN
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHCC
PVDAIGSVANYFSEHNWQPGLPVAARARLHGTGYVALAKKGYKPSFTLAQANSAGVTALS
CHHHHHHHHHHHHHCCCCCCCCHHHHHEECCCEEEEEECCCCCCCEEEEECCCCCEEEEE
CNDDRLVSEYCFDLPASTRVALLDLTGTDGAEFWLATDNFYVITRYNHSRLYAMAVLQLS
CCCCHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEECCEEEEEEECCHHHHHHHHHHHH
RQLAAALEDNQ
HHHHHHHCCCC
>Mature Secondary Structure
MEIMKTGEPPLRRFYLGILNIFRSGTAYSAIAVAALFFTSLPALAEHTCPENNDYLQRKQ
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VQALIAELVSQGQDEARLREVLGSAQCQPQILKSIARPAERTHTWATYQKIFLQESRVQK
HHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
GIEFAHTHAKTLTRAEQTYGVPREIILAIIGVETRYGDHMGNYRVVDALATLGYDYPPRG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHCCCCCCCC
SFFRKQLKALFELEHHAHIDANTITGSYAGAMGYGQFIPTSYQAYAVDFDNDGITDLVNN
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHCC
PVDAIGSVANYFSEHNWQPGLPVAARARLHGTGYVALAKKGYKPSFTLAQANSAGVTALS
CHHHHHHHHHHHHHCCCCCCCCHHHHHEECCCEEEEEECCCCCCCEEEEECCCCCEEEEE
CNDDRLVSEYCFDLPASTRVALLDLTGTDGAEFWLATDNFYVITRYNHSRLYAMAVLQLS
CCCCHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEECCEEEEEEECCHHHHHHHHHHHH
RQLAAALEDNQ
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7476170; 7789526; 9205837; 9278503; 3553176; 9761817; 10570954; 10545329; 10684641 [H]