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The map label for this gene is selD [H]

Identifier: 110834586

GI number: 110834586

Start: 1963315

End: 1965531

Strand: Direct

Name: selD [H]

Synonym: ABO_1725

Alternate gene names: 110834586

Gene position: 1963315-1965531 (Clockwise)

Preceding gene: 110834585

Following gene: 110834587

Centisome position: 62.92

GC content: 61.25

Gene sequence:

>2217_bases
GTGATAAGTCCCTCCGCCCACTACGACCTGGTCTTTGTCGGTGCTGGCCATAGCCACGCGCTGGCCCTGCGCATGCTGGC
CATGAAGCCGATTCCCGGCGTGCGCCTGACTCTGGTTTCACCGGACAGCCTTAGCGCCTACTCCGGCATGTTGCCAGGGC
TGATCGCCGGCCACTACACCCTGGATGACACCCACGTGGATGTCTACCGGTTGTGCCAGGCTAGCGGCTGCCGTTTTATT
CAAGCCAGCGTCACCCAGCTGGACCCGCAACAGCGACACTTACAGCTCAGCGATGGCAGCCAACTGGCCTACGATTGGTT
AAGCCTGGACGTGGGCGCCACCCCGGATTTGAGCCCTCTGGGCGGCAGCCACCCCCGTGTGGTCCCGGTGAAGCCAGTGG
CCAGTTTCTATGCCCGCTGGCAGCAACTCTGCCAACACGCCGAACGGCAATCGCCCTCGTTGGCAGTGATCGGCGCCGGG
GCCGGCGGTACCGAGATGACCCTGGCCATGGCCCAACATTTCCAGCGCCACCAGCAACCGGCACAGATTCAATTGATCAC
CAGCGGCAATCTACTGCCGGGCTTTCCTGCCAGCGTGCGCGAGAAAATGCACAAGCGGCTGCAAGCCCACAACGTCACCC
TGCATACCGACAGTCGCGTTCATTGTGATGCTCATCAGCAACTGCATATGGGAGATCAGCCACTCACCGCCCAATGGGTG
CTCTGGTGCACCGGGGTACGGGGCTTACCGATACTGGAAAACAGCGGCCTTGAGTGCGACGAACGAGGTTTTGTGCGGGT
CACGGAAACCCTGCAAACGGCCACTGATAAACGCATTTTTGCCGCAGGTGATTGTGCCGCCTTCCCTACGCCGCTGCCCA
AGGCCGGGGTCTATGCTGTTCGCCAGGCTCGCACCCTGGCCACCAACCTACGCGCCGTCATTCAAGGGCAACCGCTAGTC
GCCTATCGCCCGCAATCCCGTTTCCTGTCGCTGCTGTCCACCGGCGGCAAAGACGCCATTGCCAGCCGTGGCGGCAGGCT
GTCTGTGGCCGGGCACTGGGTATGGCGCTGGAAGGATCACATCGACCGGGCGTTCATGGCCAAGTTCGATCAGCAGCTTC
CGAGCATGCCCCCTGGTCCCGCTGATCCAGATACATTGCATTGCGCCGGTTGCGGCGCCAAGGTGGGCAGTGACGCCTTG
CATGAAGCACTGGCCGAGCTGCAACCGGTGGTGAACCCCGGCATCGAAGCCGGGGTGGATGCCGCCGATGACGCGGCCAT
TATTGATTGGCCTGCCGGGCAGCGACTGGTGCAGAGCCTGGATTTCTTTCCCGCCTTTATCGATGAGCCTTACCTGTTCG
GCCGTATCGCCGCGCTGCACAGCCTCAGCGACGTGTACGCCATGAATGCCCAACCCCATTCGGCTCTGGCCAACATCACC
CTGCCCTGGCACCACCCGCGACTGCAGAGCCGGGACCTGCAACGGATGATGGCAGGCGCGGTTCGCGAGCTGAATGCCGC
AGGCTGCACCCTGGTAGGTGGGCACACCATCGAAGGGCCACAGATGGCCGCCGGGTTCACCGTCAATGGCCAGGCAGACC
CAGCACAGCTCTGGCACAAACACGGCGCCCGTGACGGCGACCGCCTTATCCTCACCAAGCCGCTGGGTAGCGGGGTGCAA
TTGGCCGCCTTGATGCAGGTTAGCCGCGAGCCGAGCTCCGCGTTCCACGGCCCCTGGCTGGACACCACCCTGCGCCATCT
TCTGATCAGCAACCATCTTGCTCAGCAAGCGCTACAGGGGATACCGGTAAATGCCTGCACCGACATCACCGGCTTTGGGC
TGCTGGGTCATCTCTATGAAATCAGCCAGCAAAGCCAAGTTAGTCTGTCCGTGGACTGCCACAAGGTCCCCTTGCTACCC
GGCACGCTCTCGTTAATTGAGCAGGGTGTGGCCAGCACTCTTAGTGACGCCAATCGCCAAATACTGGTGCACTGCCAACA
GCAACAACCAGTGGCCGAAGCATTACTCACCGCGCTGTGCGACCCGCAAACCGCTGGGGGGTTGTTATTTTGCCTGCACG
CTGACTATGCCAAACAGGCACTGCAACGGCTTGATAGCAAAGGCATTGCAGCGGCGGAGATCGGTAAAGTTCTTGTAAAA
AAAACTTCTAATGATGCCGCCATTCTTTTGAATAGCGGCCACACTGGTAAAGTATAG

Upstream 100 bases:

>100_bases
GGCGGAGAATTGCACTGTCAGTTAAAAGGCGACCGCGTCACACTTAGCGGCACCGCACGCTGCTACCTGCAAGGTGAACT
GCAACTGTGATGATGCCACT

Downstream 100 bases:

>100_bases
CCATCAACCATTGAGGAGATTGCTTCATGACCCCATCCAAACGCGTTACCGGAATGCTTAGTGCCTTTGTTTTGCTATTT
ATGCAGGTGCTCATTGTACC

Product: hypothetical protein

Products: NA

Alternate protein names: Selenium donor protein; Selenophosphate synthase [H]

Number of amino acids: Translated: 738; Mature: 738

Protein sequence:

>738_residues
MISPSAHYDLVFVGAGHSHALALRMLAMKPIPGVRLTLVSPDSLSAYSGMLPGLIAGHYTLDDTHVDVYRLCQASGCRFI
QASVTQLDPQQRHLQLSDGSQLAYDWLSLDVGATPDLSPLGGSHPRVVPVKPVASFYARWQQLCQHAERQSPSLAVIGAG
AGGTEMTLAMAQHFQRHQQPAQIQLITSGNLLPGFPASVREKMHKRLQAHNVTLHTDSRVHCDAHQQLHMGDQPLTAQWV
LWCTGVRGLPILENSGLECDERGFVRVTETLQTATDKRIFAAGDCAAFPTPLPKAGVYAVRQARTLATNLRAVIQGQPLV
AYRPQSRFLSLLSTGGKDAIASRGGRLSVAGHWVWRWKDHIDRAFMAKFDQQLPSMPPGPADPDTLHCAGCGAKVGSDAL
HEALAELQPVVNPGIEAGVDAADDAAIIDWPAGQRLVQSLDFFPAFIDEPYLFGRIAALHSLSDVYAMNAQPHSALANIT
LPWHHPRLQSRDLQRMMAGAVRELNAAGCTLVGGHTIEGPQMAAGFTVNGQADPAQLWHKHGARDGDRLILTKPLGSGVQ
LAALMQVSREPSSAFHGPWLDTTLRHLLISNHLAQQALQGIPVNACTDITGFGLLGHLYEISQQSQVSLSVDCHKVPLLP
GTLSLIEQGVASTLSDANRQILVHCQQQQPVAEALLTALCDPQTAGGLLFCLHADYAKQALQRLDSKGIAAAEIGKVLVK
KTSNDAAILLNSGHTGKV

Sequences:

>Translated_738_residues
MISPSAHYDLVFVGAGHSHALALRMLAMKPIPGVRLTLVSPDSLSAYSGMLPGLIAGHYTLDDTHVDVYRLCQASGCRFI
QASVTQLDPQQRHLQLSDGSQLAYDWLSLDVGATPDLSPLGGSHPRVVPVKPVASFYARWQQLCQHAERQSPSLAVIGAG
AGGTEMTLAMAQHFQRHQQPAQIQLITSGNLLPGFPASVREKMHKRLQAHNVTLHTDSRVHCDAHQQLHMGDQPLTAQWV
LWCTGVRGLPILENSGLECDERGFVRVTETLQTATDKRIFAAGDCAAFPTPLPKAGVYAVRQARTLATNLRAVIQGQPLV
AYRPQSRFLSLLSTGGKDAIASRGGRLSVAGHWVWRWKDHIDRAFMAKFDQQLPSMPPGPADPDTLHCAGCGAKVGSDAL
HEALAELQPVVNPGIEAGVDAADDAAIIDWPAGQRLVQSLDFFPAFIDEPYLFGRIAALHSLSDVYAMNAQPHSALANIT
LPWHHPRLQSRDLQRMMAGAVRELNAAGCTLVGGHTIEGPQMAAGFTVNGQADPAQLWHKHGARDGDRLILTKPLGSGVQ
LAALMQVSREPSSAFHGPWLDTTLRHLLISNHLAQQALQGIPVNACTDITGFGLLGHLYEISQQSQVSLSVDCHKVPLLP
GTLSLIEQGVASTLSDANRQILVHCQQQQPVAEALLTALCDPQTAGGLLFCLHADYAKQALQRLDSKGIAAAEIGKVLVK
KTSNDAAILLNSGHTGKV
>Mature_738_residues
MISPSAHYDLVFVGAGHSHALALRMLAMKPIPGVRLTLVSPDSLSAYSGMLPGLIAGHYTLDDTHVDVYRLCQASGCRFI
QASVTQLDPQQRHLQLSDGSQLAYDWLSLDVGATPDLSPLGGSHPRVVPVKPVASFYARWQQLCQHAERQSPSLAVIGAG
AGGTEMTLAMAQHFQRHQQPAQIQLITSGNLLPGFPASVREKMHKRLQAHNVTLHTDSRVHCDAHQQLHMGDQPLTAQWV
LWCTGVRGLPILENSGLECDERGFVRVTETLQTATDKRIFAAGDCAAFPTPLPKAGVYAVRQARTLATNLRAVIQGQPLV
AYRPQSRFLSLLSTGGKDAIASRGGRLSVAGHWVWRWKDHIDRAFMAKFDQQLPSMPPGPADPDTLHCAGCGAKVGSDAL
HEALAELQPVVNPGIEAGVDAADDAAIIDWPAGQRLVQSLDFFPAFIDEPYLFGRIAALHSLSDVYAMNAQPHSALANIT
LPWHHPRLQSRDLQRMMAGAVRELNAAGCTLVGGHTIEGPQMAAGFTVNGQADPAQLWHKHGARDGDRLILTKPLGSGVQ
LAALMQVSREPSSAFHGPWLDTTLRHLLISNHLAQQALQGIPVNACTDITGFGLLGHLYEISQQSQVSLSVDCHKVPLLP
GTLSLIEQGVASTLSDANRQILVHCQQQQPVAEALLTALCDPQTAGGLLFCLHADYAKQALQRLDSKGIAAAEIGKVLVK
KTSNDAAILLNSGHTGKV

Specific function: Synthesizes selenophosphate from selenide and ATP [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selenophosphate synthase 1 family. Class I subfamily [H]

Homologues:

Organism=Homo sapiens, GI24797148, Length=373, Percent_Identity=25.4691689008043, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI15011844, Length=289, Percent_Identity=26.643598615917, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1788062, Length=333, Percent_Identity=32.7327327327327, Blast_Score=163, Evalue=5e-41,
Organism=Escherichia coli, GI1787352, Length=308, Percent_Identity=22.7272727272727, Blast_Score=66, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17543426, Length=356, Percent_Identity=26.123595505618, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24653602, Length=370, Percent_Identity=25.6756756756757, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24653604, Length=370, Percent_Identity=25.6756756756757, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28574119, Length=279, Percent_Identity=26.5232974910394, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR004536
- InterPro:   IPR023061 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.9.3 [H]

Molecular weight: Translated: 79374; Mature: 79374

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISPSAHYDLVFVGAGHSHALALRMLAMKPIPGVRLTLVSPDSLSAYSGMLPGLIAGHYT
CCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCCHHHCCCEE
LDDTHVDVYRLCQASGCRFIQASVTQLDPQQRHLQLSDGSQLAYDWLSLDVGATPDLSPL
ECCCCHHHHHHHHHCCCEEEEHHHHHCCCHHHEEEECCCCEEEEEEEEECCCCCCCCCCC
GGSHPRVVPVKPVASFYARWQQLCQHAERQSPSLAVIGAGAGGTEMTLAMAQHFQRHQQP
CCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCC
AQIQLITSGNLLPGFPASVREKMHKRLQAHNVTLHTDSRVHCDAHQQLHMGDQPLTAQWV
CEEEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEECCCEEECCCHHHHCCCCCCCCCEEE
LWCTGVRGLPILENSGLECDERGFVRVTETLQTATDKRIFAAGDCAAFPTPLPKAGVYAV
EEECCCCCCCEECCCCCCCCCCCCEEEHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHH
RQARTLATNLRAVIQGQPLVAYRPQSRFLSLLSTGGKDAIASRGGRLSVAGHWVWRWKDH
HHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCHHHHCCCCEEEEEEEEEEEEHHH
IDRAFMAKFDQQLPSMPPGPADPDTLHCAGCGAKVGSDALHEALAELQPVVNPGIEAGVD
HHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
AADDAAIIDWPAGQRLVQSLDFFPAFIDEPYLFGRIAALHSLSDVYAMNAQPHSALANIT
CCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEECCCCCCCEEEEE
LPWHHPRLQSRDLQRMMAGAVRELNAAGCTLVGGHTIEGPQMAAGFTVNGQADPAQLWHK
CCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCEECCCCCEECCEEECCCCCHHHHHHH
HGARDGDRLILTKPLGSGVQLAALMQVSREPSSAFHGPWLDTTLRHLLISNHLAQQALQG
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
IPVNACTDITGFGLLGHLYEISQQSQVSLSVDCHKVPLLPGTLSLIEQGVASTLSDANRQ
CCCCHHCCCHHHHHHHHHHHHCCCCCEEEEECCEECCCCCHHHHHHHHHHHHHHHCCCCE
ILVHCQQQQPVAEALLTALCDPQTAGGLLFCLHADYAKQALQRLDSKGIAAAEIGKVLVK
EEEEECCCCCHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHE
KTSNDAAILLNSGHTGKV
ECCCCEEEEEECCCCCCC
>Mature Secondary Structure
MISPSAHYDLVFVGAGHSHALALRMLAMKPIPGVRLTLVSPDSLSAYSGMLPGLIAGHYT
CCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCCCCHHHCCCEE
LDDTHVDVYRLCQASGCRFIQASVTQLDPQQRHLQLSDGSQLAYDWLSLDVGATPDLSPL
ECCCCHHHHHHHHHCCCEEEEHHHHHCCCHHHEEEECCCCEEEEEEEEECCCCCCCCCCC
GGSHPRVVPVKPVASFYARWQQLCQHAERQSPSLAVIGAGAGGTEMTLAMAQHFQRHQQP
CCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCC
AQIQLITSGNLLPGFPASVREKMHKRLQAHNVTLHTDSRVHCDAHQQLHMGDQPLTAQWV
CEEEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEECCCEEECCCHHHHCCCCCCCCCEEE
LWCTGVRGLPILENSGLECDERGFVRVTETLQTATDKRIFAAGDCAAFPTPLPKAGVYAV
EEECCCCCCCEECCCCCCCCCCCCEEEHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHH
RQARTLATNLRAVIQGQPLVAYRPQSRFLSLLSTGGKDAIASRGGRLSVAGHWVWRWKDH
HHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCHHHHCCCCEEEEEEEEEEEEHHH
IDRAFMAKFDQQLPSMPPGPADPDTLHCAGCGAKVGSDALHEALAELQPVVNPGIEAGVD
HHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
AADDAAIIDWPAGQRLVQSLDFFPAFIDEPYLFGRIAALHSLSDVYAMNAQPHSALANIT
CCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEECCCCCCCEEEEE
LPWHHPRLQSRDLQRMMAGAVRELNAAGCTLVGGHTIEGPQMAAGFTVNGQADPAQLWHK
CCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCEECCCCCEECCEEECCCCCHHHHHHH
HGARDGDRLILTKPLGSGVQLAALMQVSREPSSAFHGPWLDTTLRHLLISNHLAQQALQG
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
IPVNACTDITGFGLLGHLYEISQQSQVSLSVDCHKVPLLPGTLSLIEQGVASTLSDANRQ
CCCCHHCCCHHHHHHHHHHHHCCCCCEEEEECCEECCCCCHHHHHHHHHHHHHHHCCCCE
ILVHCQQQQPVAEALLTALCDPQTAGGLLFCLHADYAKQALQRLDSKGIAAAEIGKVLVK
EEEEECCCCCHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHE
KTSNDAAILLNSGHTGKV
ECCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA