Click here to switch to the map view.

The map label for this gene is acdA [H]

Identifier: 110834124

GI number: 110834124

Start: 1437758

End: 1438852

Strand: Direct

Name: acdA [H]

Synonym: ABO_1263

Alternate gene names: 110834124

Gene position: 1437758-1438852 (Clockwise)

Preceding gene: 110834121

Following gene: 110834125

Centisome position: 46.08

GC content: 55.16

Gene sequence:

>1095_bases
ATGTCTACACCGCTTTTTGACCTGACATTAACTGAAGAGCAACGCATGACCCGTGAAGGGATGCGCAAGCTGGTTCGAGA
TTCCCTGTTTCCACAATCGCGTGAAGCAGATGACGCGGCGAAGGCGAATGCTCAACTGCTAAACAGTATCGCGGGTTTTG
GTTTGTCGTTGATGCCGATGCCCGAAGCACTGGGTGGCGTGGGCATGCCTCGCTCACCGCTGTCCAACGCTTTGGCGGTA
GAAGACCTTGCCCAAGGGGATATTTCCCACACGTTAGCAGCCTTGCAGCCGATGGCGGCAGTGAATGCATTGATAGATTT
TGGTAATGAAGACCAGCAAGAACGCTGGTTGCCATCCATGGCTACAGAAAGCTTCACTGGGGCGGCTATCGCATTGACAG
AGCCCCGTGCCACTTTTGAGCCATCCTCACCGGCCACCACGGCACAAAGCGCCGATGGACAAGTGGTACTGAACGGTGTG
AAAAGCATGGTGCCGTTAGCAGCACAATGTGAGTGGTTTGTGGTGGTAGCGGCGGAAAAGGATGACGTATCTGCTTTTAT
CGTGCCGAAAACCGCAGCAGGCCTAACAATCGAATCGCAAGCGTATATGGGACTTCGTAGTGCTGAGCTGGCCACGTTGA
CTTTAGAATCAGTGGTGGTTCCGGAGGCCGATCGCTTGGAGCGCTTTGACCTGAATCGTTTGCTGGGTCTGGCTCGCATT
GGCCAATGCGCCTTGGCGGTGGGGTGCTGTCAGGCGGTAATGGAGTACGCCATCCCTTATGTGAATGAGCGTAAGGCATT
TGGTGAACCGATTGCCTGGCGCCAGTCTGTGGCCTTTATGGTGGCCAATATGGCGATCGAGATTGAAGGGATGCGGCTGA
TGATGTTGCGCGCCGCCAGCCGGGCCGAACAGGGGCTGGATTTCCACAAGGAAGCCTATCTTGCGCAGCTATTGTGCATG
GAAAAGGCCATGGAAATTGGCACCAACGGTATTCAGCTCTTCGGTGGAGCGGGCTTTGTTCGCGACTACCCACTAGAGAT
GTGGTACCGGAACTTGCGCAGCATTGCCGTGCTTCACGGCAGCCTGATGGTGTAG

Upstream 100 bases:

>100_bases
TTTATCGGCCCAGGTCACAGGCCTGTCATTGTCGATAGTAGACAGCCAATGACAGACTGTTGTTCAACTAACTGTATGTT
TGCCGGGATGAGGCCCTCGT

Downstream 100 bases:

>100_bases
GAGAACAGCATGATTAATTTAGAATTGCCCGAGAAGCTTAAACAAACCCAGCAGATGGCCCAGCAACTGGCCAGCGGTGT
TTTTCGCCCGATTTCACGCA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSTPLFDLTLTEEQRMTREGMRKLVRDSLFPQSREADDAAKANAQLLNSIAGFGLSLMPMPEALGGVGMPRSPLSNALAV
EDLAQGDISHTLAALQPMAAVNALIDFGNEDQQERWLPSMATESFTGAAIALTEPRATFEPSSPATTAQSADGQVVLNGV
KSMVPLAAQCEWFVVVAAEKDDVSAFIVPKTAAGLTIESQAYMGLRSAELATLTLESVVVPEADRLERFDLNRLLGLARI
GQCALAVGCCQAVMEYAIPYVNERKAFGEPIAWRQSVAFMVANMAIEIEGMRLMMLRAASRAEQGLDFHKEAYLAQLLCM
EKAMEIGTNGIQLFGGAGFVRDYPLEMWYRNLRSIAVLHGSLMV

Sequences:

>Translated_364_residues
MSTPLFDLTLTEEQRMTREGMRKLVRDSLFPQSREADDAAKANAQLLNSIAGFGLSLMPMPEALGGVGMPRSPLSNALAV
EDLAQGDISHTLAALQPMAAVNALIDFGNEDQQERWLPSMATESFTGAAIALTEPRATFEPSSPATTAQSADGQVVLNGV
KSMVPLAAQCEWFVVVAAEKDDVSAFIVPKTAAGLTIESQAYMGLRSAELATLTLESVVVPEADRLERFDLNRLLGLARI
GQCALAVGCCQAVMEYAIPYVNERKAFGEPIAWRQSVAFMVANMAIEIEGMRLMMLRAASRAEQGLDFHKEAYLAQLLCM
EKAMEIGTNGIQLFGGAGFVRDYPLEMWYRNLRSIAVLHGSLMV
>Mature_363_residues
STPLFDLTLTEEQRMTREGMRKLVRDSLFPQSREADDAAKANAQLLNSIAGFGLSLMPMPEALGGVGMPRSPLSNALAVE
DLAQGDISHTLAALQPMAAVNALIDFGNEDQQERWLPSMATESFTGAAIALTEPRATFEPSSPATTAQSADGQVVLNGVK
SMVPLAAQCEWFVVVAAEKDDVSAFIVPKTAAGLTIESQAYMGLRSAELATLTLESVVVPEADRLERFDLNRLLGLARIG
QCALAVGCCQAVMEYAIPYVNERKAFGEPIAWRQSVAFMVANMAIEIEGMRLMMLRAASRAEQGLDFHKEAYLAQLLCME
KAMEIGTNGIQLFGGAGFVRDYPLEMWYRNLRSIAVLHGSLMV

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=364, Percent_Identity=29.3956043956044, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI4501859, Length=365, Percent_Identity=28.7671232876712, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI226958412, Length=363, Percent_Identity=26.9972451790634, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=25.8575197889182, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=25.8575197889182, Blast_Score=124, Evalue=9e-29,
Organism=Homo sapiens, GI7656849, Length=368, Percent_Identity=27.445652173913, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI226958414, Length=326, Percent_Identity=26.0736196319018, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI76496475, Length=393, Percent_Identity=25.4452926208651, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4557235, Length=393, Percent_Identity=25.4452926208651, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI21361497, Length=348, Percent_Identity=25.5747126436782, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI4501857, Length=370, Percent_Identity=23.2432432432432, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4503943, Length=361, Percent_Identity=24.0997229916898, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7669494, Length=371, Percent_Identity=24.2587601078167, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI48976061, Length=277, Percent_Identity=28.8808664259928, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI211971008, Length=277, Percent_Identity=28.8808664259928, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87081958, Length=366, Percent_Identity=27.8688524590164, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1786223, Length=385, Percent_Identity=24.9350649350649, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17570075, Length=378, Percent_Identity=30.6878306878307, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=28.2321899736148, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17534899, Length=375, Percent_Identity=28.8, Blast_Score=141, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17506239, Length=355, Percent_Identity=26.4788732394366, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17508101, Length=364, Percent_Identity=25, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI71990804, Length=298, Percent_Identity=28.1879194630872, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17533517, Length=358, Percent_Identity=25.4189944134078, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=384, Percent_Identity=26.3020833333333, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=353, Percent_Identity=24.929178470255, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982178, Length=271, Percent_Identity=29.1512915129151, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=363, Percent_Identity=23.4159779614325, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32563615, Length=225, Percent_Identity=25.3333333333333, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=370, Percent_Identity=23.2432432432432, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551932, Length=378, Percent_Identity=23.015873015873, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=354, Percent_Identity=24.2937853107345, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24666513, Length=372, Percent_Identity=31.4516129032258, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI21356377, Length=364, Percent_Identity=28.8461538461538, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24646207, Length=369, Percent_Identity=29.810298102981, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24660351, Length=372, Percent_Identity=28.7634408602151, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI281363737, Length=355, Percent_Identity=27.0422535211268, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI19920834, Length=363, Percent_Identity=26.1707988980716, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21355753, Length=352, Percent_Identity=23.5795454545455, Blast_Score=85, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 39457; Mature: 39326

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPLFDLTLTEEQRMTREGMRKLVRDSLFPQSREADDAAKANAQLLNSIAGFGLSLMPM
CCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCC
PEALGGVGMPRSPLSNALAVEDLAQGDISHTLAALQPMAAVNALIDFGNEDQQERWLPSM
CHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHH
ATESFTGAAIALTEPRATFEPSSPATTAQSADGQVVLNGVKSMVPLAAQCEWFVVVAAEK
HHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCEEEEEEECC
DDVSAFIVPKTAAGLTIESQAYMGLRSAELATLTLESVVVPEADRLERFDLNRLLGLARI
CCCEEEEEECCCCCCEEECHHHCCCCCCHHHEEEHHHHCCCCHHHHHHHHHHHHHHHHHH
GQCALAVGCCQAVMEYAIPYVNERKAFGEPIAWRQSVAFMVANMAIEIEGMRLMMLRAAS
HHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHEEEECCHHHHHHHHHH
RAEQGLDFHKEAYLAQLLCMEKAMEIGTNGIQLFGGAGFVRDYPLEMWYRNLRSIAVLHG
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHCCCHHHHHHHHHHHHHHHH
SLMV
HHCC
>Mature Secondary Structure 
STPLFDLTLTEEQRMTREGMRKLVRDSLFPQSREADDAAKANAQLLNSIAGFGLSLMPM
CCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCEEECCC
PEALGGVGMPRSPLSNALAVEDLAQGDISHTLAALQPMAAVNALIDFGNEDQQERWLPSM
CHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHH
ATESFTGAAIALTEPRATFEPSSPATTAQSADGQVVLNGVKSMVPLAAQCEWFVVVAAEK
HHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCEEEEEEECC
DDVSAFIVPKTAAGLTIESQAYMGLRSAELATLTLESVVVPEADRLERFDLNRLLGLARI
CCCEEEEEECCCCCCEEECHHHCCCCCCHHHEEEHHHHCCCCHHHHHHHHHHHHHHHHHH
GQCALAVGCCQAVMEYAIPYVNERKAFGEPIAWRQSVAFMVANMAIEIEGMRLMMLRAAS
HHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHEEEECCHHHHHHHHHH
RAEQGLDFHKEAYLAQLLCMEKAMEIGTNGIQLFGGAGFVRDYPLEMWYRNLRSIAVLHG
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHCCCHHHHHHHHHHHHHHHH
SLMV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]