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The map label for this gene is clpP [H]

Identifier: 110834071

GI number: 110834071

Start: 1375557

End: 1376213

Strand: Direct

Name: clpP [H]

Synonym: ABO_1210

Alternate gene names: 110834071

Gene position: 1375557-1376213 (Clockwise)

Preceding gene: 110834070

Following gene: 110834072

Centisome position: 44.09

GC content: 50.23

Gene sequence:

>657_bases
ATGATCGACTTCAGCCGTATTAACTCGCTTACCCCGGAAATGAGTCAGCTCATCAAAGATCCGACTAACCTGGGTTTGGT
ACCGGTGGTGATCGAGCAGACTGCCCGTGGAGAGCGTTCTTTTGATATTTACTCCCGCCTTTTAAAGGAGCGAGTGATCT
TCATGATCGGTCAGGTGGAAGACCATATGGCCAACCTGATTGTGGCGCAGATGCTATTTCTAGAATCTGAGAACCCGGAC
AAAGATATCCATCTGTATATCAATAGCCCAGGGGGTTCGGTAACAGCAGGGATGTCCATCTACGACACCATGCAGTTCAT
CAAGCCGGATGTATCCACTATGTGTATTGGCCAGGCGGCCAGCATGGGCGCTTTTCTGCTTACCGCGGGTGCTGCTGGCA
AGCGTTTTGCGCTACCCAATGCCCGGGTGATGATTCATCAACCACTGGGTGGTTTTCAGGGTCAGGCGTCAGATATCGAG
ATCCACGCCAAGGAAATCCTAAAAATCAAAGGCCAATTAAACAGTTTGCTGGCGCATCACACCGGCCAGCCAATTGAACA
GCTGGAAAAAGATACTGACCGCGATAACTTTATGAGTGCCGACGAAGCAAAAGAATACGGCATCATTGACGCGGTATTGA
GCCAGCGCCCTGTTTAA

Upstream 100 bases:

>100_bases
AACCCCCCAAGACAGCCCAAGTACATGCCGGTTGTTGACCGCCGACATCAATAAACAGTTGAGAGTGTCCACGGACAATC
AACGAGAAGGATAGCGCTAC

Downstream 100 bases:

>100_bases
TAGGCTTGTTGGTACAAGAACAGTTCTAACGGTGCGGTATAGCAGCTCGGTGGGCTTGAAAAACAGCGGGCGACACGGCA
TCTTCAAAGCAAATACACAG

Product: ATP-dependent Clp protease, proteolytic subunitclpp

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MIDFSRINSLTPEMSQLIKDPTNLGLVPVVIEQTARGERSFDIYSRLLKERVIFMIGQVEDHMANLIVAQMLFLESENPD
KDIHLYINSPGGSVTAGMSIYDTMQFIKPDVSTMCIGQAASMGAFLLTAGAAGKRFALPNARVMIHQPLGGFQGQASDIE
IHAKEILKIKGQLNSLLAHHTGQPIEQLEKDTDRDNFMSADEAKEYGIIDAVLSQRPV

Sequences:

>Translated_218_residues
MIDFSRINSLTPEMSQLIKDPTNLGLVPVVIEQTARGERSFDIYSRLLKERVIFMIGQVEDHMANLIVAQMLFLESENPD
KDIHLYINSPGGSVTAGMSIYDTMQFIKPDVSTMCIGQAASMGAFLLTAGAAGKRFALPNARVMIHQPLGGFQGQASDIE
IHAKEILKIKGQLNSLLAHHTGQPIEQLEKDTDRDNFMSADEAKEYGIIDAVLSQRPV
>Mature_218_residues
MIDFSRINSLTPEMSQLIKDPTNLGLVPVVIEQTARGERSFDIYSRLLKERVIFMIGQVEDHMANLIVAQMLFLESENPD
KDIHLYINSPGGSVTAGMSIYDTMQFIKPDVSTMCIGQAASMGAFLLTAGAAGKRFALPNARVMIHQPLGGFQGQASDIE
IHAKEILKIKGQLNSLLAHHTGQPIEQLEKDTDRDNFMSADEAKEYGIIDAVLSQRPV

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=194, Percent_Identity=56.1855670103093, Blast_Score=243, Evalue=8e-65,
Organism=Escherichia coli, GI1786641, Length=194, Percent_Identity=78.8659793814433, Blast_Score=337, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI17538017, Length=186, Percent_Identity=54.3010752688172, Blast_Score=224, Evalue=3e-59,
Organism=Drosophila melanogaster, GI20129427, Length=195, Percent_Identity=58.4615384615385, Blast_Score=255, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 24030; Mature: 24030

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00381 CLP_PROTEASE_SER ; PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFSRINSLTPEMSQLIKDPTNLGLVPVVIEQTARGERSFDIYSRLLKERVIFMIGQVE
CCCHHHHHCCCHHHHHHHCCCCCCCEEHHEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
DHMANLIVAQMLFLESENPDKDIHLYINSPGGSVTAGMSIYDTMQFIKPDVSTMCIGQAA
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECHHHHHHHHHHCCCHHHHHHHHHH
SMGAFLLTAGAAGKRFALPNARVMIHQPLGGFQGQASDIEIHAKEILKIKGQLNSLLAHH
HHCHHEEECCCCCCEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
TGQPIEQLEKDTDRDNFMSADEAKEYGIIDAVLSQRPV
CCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIDFSRINSLTPEMSQLIKDPTNLGLVPVVIEQTARGERSFDIYSRLLKERVIFMIGQVE
CCCHHHHHCCCHHHHHHHCCCCCCCEEHHEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
DHMANLIVAQMLFLESENPDKDIHLYINSPGGSVTAGMSIYDTMQFIKPDVSTMCIGQAA
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECHHHHHHHHHHCCCHHHHHHHHHH
SMGAFLLTAGAAGKRFALPNARVMIHQPLGGFQGQASDIEIHAKEILKIKGQLNSLLAHH
HHCHHEEECCCCCCEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
TGQPIEQLEKDTDRDNFMSADEAKEYGIIDAVLSQRPV
CCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA