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The map label for this gene is clpX

Identifier: 110834072

GI number: 110834072

Start: 1376330

End: 1377610

Strand: Direct

Name: clpX

Synonym: ABO_1211

Alternate gene names: 110834072

Gene position: 1376330-1377610 (Clockwise)

Preceding gene: 110834071

Following gene: 110834073

Centisome position: 44.11

GC content: 51.13

Gene sequence:

>1281_bases
ATGACCGATTCCACTGGCAAGGGCGACGACGGCAAGTTGCTGTATTGCTCATTCTGCGGCAAAAGCCAGCATGAGGTACG
CAAGCTAATTGCGGGGCCCTCGGTCTTTATTTGCGATGAATGCGTGGATCTGTGTAACGACATTATCCGCGAGGAAGTGC
AGGAAGACACCAGCGAGACTGATGGCGAACGCCTGCCTAAGCCCAATGAAATTAAAGATACCCTCGACGAGTACGTGATT
GGCCAAGAAAGGGCCAAGAAGGTGTTGGCCGTGGCGGTTTACAACCACTACAAGCGCCTGCGCAGTGGTGGCAAAGGCCG
TGATGAAGTTGAGTTGGGTAAGAGTAATATTTTGCTTATTGGTCCTACCGGTAGTGGTAAGACCCTGTTGGCAGAAACGT
TGGCCCGCATGTTGAACGTGCCCTTTACCATTGCTGATGCCACCACCCTTACCGAAGCCGGTTATGTCGGTGAGGACGTG
GAAAATATTATTCAAAAATTGCTACAGAAATGTGATTACGATGTGGACAAGGCTCAGCGCGGCATCGTTTATATCGATGA
AATCGATAAGATTTCTCGCAAATCGGACAATCCCTCTATTACCCGTGATGTGAGTGGGGAGGGTGTTCAGCAAGCGCTGT
TGAAGTTAATTGAAGGCACTGTAGCCTCAGTGCCACCTCAGGGTGGGCGCAAACATCCTCAGCAAGAGTTTCTGCAAGTA
GACACCTCGAACATGCTATTTATCTGTGGCGGAGCCTTCGCGGGCCTGGACAAGGTGATCCGCGAGCGCTCTGAAAAGGG
GGGGATTGGTTTCTCCGCTGAGGTGAAGAGCAAAGATAATACGCGCAATCTGGGTGAGCTATTGGTCGATGTTGAACCAG
AGGATCTGGTCAAGTACGGCCTGATTCCAGAGTTTATTGGTCGCCTACCCGTTATCGCTACTCTGGAAGAGCTTAGCGAG
GATGCACTAATTCAGATCCTCACAGAGCCGCGCAATGCATTGACCAAGCAGTATGCTCGCCTGTTCGAGATGGAAGGGGT
GGAGCTGGACTTTCGCGAAGATGCATTAAAAGCGATTGCCAACAAGGCGATGGTGCGCAAAACGGGTGCCAGGGGCTTGC
GTTCAATTCTGGAAAGCGTGCTGCTTGATACCATGTATCAGGTGCCATCCATGGAGAGCGTTGCCAAGGTAGTTATTGAT
AGCCCTACTATCAAAGGCGAATCTGAGCCCTTGTTGATTTACGAAAACAACGAGCAGTCTTCCAAGGTCGCGCCGGATTG
A

Upstream 100 bases:

>100_bases
AGAACAGTTCTAACGGTGCGGTATAGCAGCTCGGTGGGCTTGAAAAACAGCGGGCGACACGGCATCTTCAAAGCAAATAC
ACAGGTTTAGAGGCAATTCG

Downstream 100 bases:

>100_bases
GATCTGGACAGAGTCCGGATCCGTCCTTGTGCAACCTAAGTCATAGAGGCAATACGTGCTGAAAGATATTCCGCTTTTAC
CGCTGCGTGATGTAGTAGTG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTDSTGKGDDGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEDTSETDGERLPKPNEIKDTLDEYVI
GQERAKKVLAVAVYNHYKRLRSGGKGRDEVELGKSNILLIGPTGSGKTLLAETLARMLNVPFTIADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
DTSNMLFICGGAFAGLDKVIRERSEKGGIGFSAEVKSKDNTRNLGELLVDVEPEDLVKYGLIPEFIGRLPVIATLEELSE
DALIQILTEPRNALTKQYARLFEMEGVELDFREDALKAIANKAMVRKTGARGLRSILESVLLDTMYQVPSMESVAKVVID
SPTIKGESEPLLIYENNEQSSKVAPD

Sequences:

>Translated_426_residues
MTDSTGKGDDGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEDTSETDGERLPKPNEIKDTLDEYVI
GQERAKKVLAVAVYNHYKRLRSGGKGRDEVELGKSNILLIGPTGSGKTLLAETLARMLNVPFTIADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
DTSNMLFICGGAFAGLDKVIRERSEKGGIGFSAEVKSKDNTRNLGELLVDVEPEDLVKYGLIPEFIGRLPVIATLEELSE
DALIQILTEPRNALTKQYARLFEMEGVELDFREDALKAIANKAMVRKTGARGLRSILESVLLDTMYQVPSMESVAKVVID
SPTIKGESEPLLIYENNEQSSKVAPD
>Mature_425_residues
TDSTGKGDDGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEDTSETDGERLPKPNEIKDTLDEYVIG
QERAKKVLAVAVYNHYKRLRSGGKGRDEVELGKSNILLIGPTGSGKTLLAETLARMLNVPFTIADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVD
TSNMLFICGGAFAGLDKVIRERSEKGGIGFSAEVKSKDNTRNLGELLVDVEPEDLVKYGLIPEFIGRLPVIATLEELSED
ALIQILTEPRNALTKQYARLFEMEGVELDFREDALKAIANKAMVRKTGARGLRSILESVLLDTMYQVPSMESVAKVVIDS
PTIKGESEPLLIYENNEQSSKVAPD

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=414, Percent_Identity=45.8937198067633, Blast_Score=317, Evalue=1e-86,
Organism=Escherichia coli, GI1786642, Length=415, Percent_Identity=79.2771084337349, Blast_Score=659, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=46, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=45.8333333333333, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=312, Percent_Identity=45.8333333333333, Blast_Score=264, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=390, Percent_Identity=38.974358974359, Blast_Score=253, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=250, Percent_Identity=40.4, Blast_Score=174, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=425, Percent_Identity=40, Blast_Score=274, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=48.1132075471698, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=48.1132075471698, Blast_Score=290, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_ALCBS (Q0VQ89)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692931.1
- ProteinModelPortal:   Q0VQ89
- SMR:   Q0VQ89
- STRING:   Q0VQ89
- GeneID:   4212465
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_1211
- NMPDR:   fig|393595.12.peg.1224
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- PhylomeDB:   Q0VQ89
- ProtClustDB:   PRK05342
- BioCyc:   ABOR393595:ABO_1211-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46885; Mature: 46754

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSTGKGDDGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEDTSET
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCC
DGERLPKPNEIKDTLDEYVIGQERAKKVLAVAVYNHYKRLRSGGKGRDEVELGKSNILLI
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEE
GPTGSGKTLLAETLARMLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVDKAQR
ECCCCCCHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCC
GIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
CEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHC
DTSNMLFICGGAFAGLDKVIRERSEKGGIGFSAEVKSKDNTRNLGELLVDVEPEDLVKYG
CCCCEEEEECCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHEECCCHHHHHHHC
LIPEFIGRLPVIATLEELSEDALIQILTEPRNALTKQYARLFEMEGVELDFREDALKAIA
CCHHHHCCCCHHHHHHHHCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
NKAMVRKTGARGLRSILESVLLDTMYQVPSMESVAKVVIDSPTIKGESEPLLIYENNEQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCC
SKVAPD
CCCCCC
>Mature Secondary Structure 
TDSTGKGDDGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEDTSET
CCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCC
DGERLPKPNEIKDTLDEYVIGQERAKKVLAVAVYNHYKRLRSGGKGRDEVELGKSNILLI
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEE
GPTGSGKTLLAETLARMLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVDKAQR
ECCCCCCHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCC
GIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
CEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHC
DTSNMLFICGGAFAGLDKVIRERSEKGGIGFSAEVKSKDNTRNLGELLVDVEPEDLVKYG
CCCCEEEEECCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHEECCCHHHHHHHC
LIPEFIGRLPVIATLEELSEDALIQILTEPRNALTKQYARLFEMEGVELDFREDALKAIA
CCHHHHCCCCHHHHHHHHCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
NKAMVRKTGARGLRSILESVLLDTMYQVPSMESVAKVVIDSPTIKGESEPLLIYENNEQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCC
SKVAPD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA