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The map label for this gene is tig

Identifier: 110834070

GI number: 110834070

Start: 1373956

End: 1375269

Strand: Direct

Name: tig

Synonym: ABO_1209

Alternate gene names: 110834070

Gene position: 1373956-1375269 (Clockwise)

Preceding gene: 110834068

Following gene: 110834071

Centisome position: 44.04

GC content: 52.44

Gene sequence:

>1314_bases
ATGCAGGTTTCTGTTGAAACGACTTCAGGTCTTGAGCGCCGTGTGACGGTGGGTGTACCCGCAGAAAAAGTGGACGTGGC
AGTAGAAGGCAAGCTGCAGGAAGCCCAGAAAACAATCCGTCTGGACGGCTTCCGTCCAGGTAAAGTGCCCATGCGTGAAG
TAAAGCGTCGCTTTGGCGGGGCTGTGCGTAACGAAGTGCTGGCTGACGTCATGCGCGAAGCTTTCATTGAAGCAGTTGAG
CAGGAAAAACTGCAGCCAGCAGGCATGCCGGGCTTTGAGGCTACCACTAACGAAGCGGGCAAGGATCTGGAATTTGTTGC
CACCTTCGAGGTTTATCCGCAAGTCGAGCTGGCAGCGTTCGATAGCATTGAGGTTGAGAAGCCCCAGTCTGAAGTTACCG
ATGCTGATGTGGATACTATGATCGAAACGCTGCGTCAGCAGCGCGCTGAGTTTGCTGATGTAGATCGCGCCAGTGAGATC
GGCGACCGCGTTAATATTGATTTTAAAGGCCTGAAGGACGGCGAAGCCTTTGAGGGTGGCACCGCTGAAGGCCAGAACCT
TGAGCTGGGCTCTGGCCAGATGATTCCGGGTTTCGAGGATGGCATCGTCGGTATGAAAGCCGGTGAAGAAAAAGACATCG
ATGTGACCTTCCCGGAAGATTACCAGTCCGAAGACCTTAAAGGTCAGGCAGTTGTGTTCCATATCAAGGTCAACAAAGTA
GAAGGTAAGGCTTTGCCGGAAGTGGACGCTGAGTTCATGAAAGGATTTGGCGTTGACGACGGCGACGAAACCAAGTTTAA
GGCTGAAGTGCGCAAAAATATGGAGCGTGAGCTCAAAAACGCTATCACTAGCAAGGTGAAAGAGCAGGCAATGGACGGGT
TGGTCAACTTGCACGAGTTTGACCTGCCGGGTGCTCTGGTAACCCAGGAAATTCAGCGCATGCGTCAACAGATGATGCAG
CAGTTCGGTGGTGGTCAGCAGTTCGACCCCTCCATCCTGCCGGATGATCTATTTAAAGAGCAAGCTGAGCGCTCCGTGCG
TTTGGGGCTGGTTGTTCGTGCCATTCTCGACAAAAACGAAATCAAGGCCGATGCCGATAAGGTAAAAGCTCGGGTTGAAG
AAATTTCCGAGCAGTACGAAAAGCCTGAAGAAGTGGTGAGCTGGGTATACAGCAATCCTCAGCAGTTGCAGCAGATTGAA
GGCGCTATTCTTGAAGAGCAGGTTGTTGATCTTGTGCTGGAAAGCGCAAAGGTTGAAGAGAAAACCATGCCCTACCAGGA
TGCAGTGAAGCCCCGCGAGCAAGCGGATGGCTAA

Upstream 100 bases:

>100_bases
AGAGAAGCTCCCTTGAACTATAATCTTCGCCCTTCATTAGGCCGTCTTCGCGTTATTTCGGCGGCGGGCAGAGATATAAG
TCTTTTTTAAAGAGGATGTT

Downstream 100 bases:

>100_bases
CGGAAGCTCCTCTGTTGGACCTTCGAAACGGGGCCTTTGGGCCTCGTTTTGCGTTATTTATGCACAATTTGCGCAAGAAT
TGCGCACTTGAACCTTTCTC

Product: trigger factor protein

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MQVSVETTSGLERRVTVGVPAEKVDVAVEGKLQEAQKTIRLDGFRPGKVPMREVKRRFGGAVRNEVLADVMREAFIEAVE
QEKLQPAGMPGFEATTNEAGKDLEFVATFEVYPQVELAAFDSIEVEKPQSEVTDADVDTMIETLRQQRAEFADVDRASEI
GDRVNIDFKGLKDGEAFEGGTAEGQNLELGSGQMIPGFEDGIVGMKAGEEKDIDVTFPEDYQSEDLKGQAVVFHIKVNKV
EGKALPEVDAEFMKGFGVDDGDETKFKAEVRKNMERELKNAITSKVKEQAMDGLVNLHEFDLPGALVTQEIQRMRQQMMQ
QFGGGQQFDPSILPDDLFKEQAERSVRLGLVVRAILDKNEIKADADKVKARVEEISEQYEKPEEVVSWVYSNPQQLQQIE
GAILEEQVVDLVLESAKVEEKTMPYQDAVKPREQADG

Sequences:

>Translated_437_residues
MQVSVETTSGLERRVTVGVPAEKVDVAVEGKLQEAQKTIRLDGFRPGKVPMREVKRRFGGAVRNEVLADVMREAFIEAVE
QEKLQPAGMPGFEATTNEAGKDLEFVATFEVYPQVELAAFDSIEVEKPQSEVTDADVDTMIETLRQQRAEFADVDRASEI
GDRVNIDFKGLKDGEAFEGGTAEGQNLELGSGQMIPGFEDGIVGMKAGEEKDIDVTFPEDYQSEDLKGQAVVFHIKVNKV
EGKALPEVDAEFMKGFGVDDGDETKFKAEVRKNMERELKNAITSKVKEQAMDGLVNLHEFDLPGALVTQEIQRMRQQMMQ
QFGGGQQFDPSILPDDLFKEQAERSVRLGLVVRAILDKNEIKADADKVKARVEEISEQYEKPEEVVSWVYSNPQQLQQIE
GAILEEQVVDLVLESAKVEEKTMPYQDAVKPREQADG
>Mature_437_residues
MQVSVETTSGLERRVTVGVPAEKVDVAVEGKLQEAQKTIRLDGFRPGKVPMREVKRRFGGAVRNEVLADVMREAFIEAVE
QEKLQPAGMPGFEATTNEAGKDLEFVATFEVYPQVELAAFDSIEVEKPQSEVTDADVDTMIETLRQQRAEFADVDRASEI
GDRVNIDFKGLKDGEAFEGGTAEGQNLELGSGQMIPGFEDGIVGMKAGEEKDIDVTFPEDYQSEDLKGQAVVFHIKVNKV
EGKALPEVDAEFMKGFGVDDGDETKFKAEVRKNMERELKNAITSKVKEQAMDGLVNLHEFDLPGALVTQEIQRMRQQMMQ
QFGGGQQFDPSILPDDLFKEQAERSVRLGLVVRAILDKNEIKADADKVKARVEEISEQYEKPEEVVSWVYSNPQQLQQIE
GAILEEQVVDLVLESAKVEEKTMPYQDAVKPREQADG

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=427, Percent_Identity=50.1170960187354, Blast_Score=409, Evalue=1e-115,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_ALCBS (Q0VQ91)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692929.1
- ProteinModelPortal:   Q0VQ91
- SMR:   Q0VQ91
- STRING:   Q0VQ91
- GeneID:   4211943
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_1209
- NMPDR:   fig|393595.12.peg.1222
- eggNOG:   COG0544
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- PhylomeDB:   Q0VQ91
- BioCyc:   ABOR393595:ABO_1209-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PANTHER:   PTHR10516
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 48678; Mature: 48678

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVSVETTSGLERRVTVGVPAEKVDVAVEGKLQEAQKTIRLDGFRPGKVPMREVKRRFGG
CEEECCCCCCCCEEEEECCCHHHEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCH
AVRNEVLADVMREAFIEAVEQEKLQPAGMPGFEATTNEAGKDLEFVATFEVYPQVELAAF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEEEEC
DSIEVEKPQSEVTDADVDTMIETLRQQRAEFADVDRASEIGDRVNIDFKGLKDGEAFEGG
CCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECEEECCCCCCCCCCCC
TAEGQNLELGSGQMIPGFEDGIVGMKAGEEKDIDVTFPEDYQSEDLKGQAVVFHIKVNKV
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEEEEEE
EGKALPEVDAEFMKGFGVDDGDETKFKAEVRKNMERELKNAITSKVKEQAMDGLVNLHEF
CCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DLPGALVTQEIQRMRQQMMQQFGGGQQFDPSILPDDLFKEQAERSVRLGLVVRAILDKNE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IKADADKVKARVEEISEQYEKPEEVVSWVYSNPQQLQQIEGAILEEQVVDLVLESAKVEE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTMPYQDAVKPREQADG
HCCCHHHHCCCHHHCCC
>Mature Secondary Structure
MQVSVETTSGLERRVTVGVPAEKVDVAVEGKLQEAQKTIRLDGFRPGKVPMREVKRRFGG
CEEECCCCCCCCEEEEECCCHHHEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCH
AVRNEVLADVMREAFIEAVEQEKLQPAGMPGFEATTNEAGKDLEFVATFEVYPQVELAAF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEEEEC
DSIEVEKPQSEVTDADVDTMIETLRQQRAEFADVDRASEIGDRVNIDFKGLKDGEAFEGG
CCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECEEECCCCCCCCCCCC
TAEGQNLELGSGQMIPGFEDGIVGMKAGEEKDIDVTFPEDYQSEDLKGQAVVFHIKVNKV
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEEEEEE
EGKALPEVDAEFMKGFGVDDGDETKFKAEVRKNMERELKNAITSKVKEQAMDGLVNLHEF
CCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DLPGALVTQEIQRMRQQMMQQFGGGQQFDPSILPDDLFKEQAERSVRLGLVVRAILDKNE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IKADADKVKARVEEISEQYEKPEEVVSWVYSNPQQLQQIEGAILEEQVVDLVLESAKVEE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTMPYQDAVKPREQADG
HCCCHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA