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The map label for this gene is eutG [H]

Identifier: 110834036

GI number: 110834036

Start: 1336222

End: 1337376

Strand: Direct

Name: eutG [H]

Synonym: ABO_1175

Alternate gene names: 110834036

Gene position: 1336222-1337376 (Clockwise)

Preceding gene: 110834035

Following gene: 110834037

Centisome position: 42.83

GC content: 58.7

Gene sequence:

>1155_bases
GTGGGGTTTGAATTTGCCACCACGCACCGCGTGCTGGTGGAAGTGGGTGCAGCCAAGCGGCTCCCTGAACTGTGTCAGCA
GCTTGGCGGCAGTCGGGTCATGTTGGTTACGGATCCAGGTATTCGCAGCACGCCGTTACTGAAGCCAGTGGAAGATAGCT
TCCGTACTGCAAACATGACCCTGGTGATTTTCGATCAGGTCAGTGCCGACCCGGCTGATTCGGTGGTGCTTAATGCCGCG
GAGCAGGCTCGCGATGCCGGTGCTGATTTAGTCATTGGTTTTGGTGGTGGCTCGTCTATGGATGTGGCCAAACTGGTGGC
ATTGCTCTCGCACCCCAAGAGCAGCCAGCAATTATCCGATATTTACGGCGTTGGCTTGGCTACCGGCCCACGGTTGCCGC
TGCTGCAGGTGCCGACGACGGCGGGGACCGGGTCAGAAGTCACGCCGGTGGCGATTGTGACCACCGGGGCGACCACTAAG
GCGGGCGTTGTCGCGCCGTCGCTCTTACCGGATCTTGCGGTACTGGATGCCGAGCTAACGCTGGGCTTGCCGCCTCAGGT
AACGGCCGCTACCGGGGTGGATGCCATGGTGCATGCTATCGAGGCTTATACCAGCGCCCATAAGAAGAACCCTTATTCCG
ACATGTTGGCCCGTGAAGCGCTGCGGCTGCTGGGAGGGAACCTGGCCACTGCCGTAAAAGAGGGCAGTAACCTGGCGGCC
CGTGAAGCTTGCCTGTTGGGCGCCATGATGGCAGGGCAGGCGTTTGCCAATGCCCCTGTGGCGGCGGTGCACGCACTGGC
ATACCCGTTGGGTGGTCACTTCCATATTCCCCATGGTTTGAGCAACTCCCTGGTGTTACCGGAGGTGTTGCGCTTTAACC
TTCCCAAGGCTGCACCGCTGTATGCGCAGCTGGCGTCGATTCTCAGTGATCGCCCCTTTGCCGACCATGAAGATGGCGCC
GGGGTGCTGATTGCGGCATTGGAGTCGCTGATCAATGAAGTGGGTTTGCCAACAAAACTGCGTGAGGTCGGTGTTAGTGA
AGACAGTTTGGACGTTCTGGCTTCAGATGCCATGTTGCAGCAGCGGTTGCTGGTCAATAACCCGCGGGAAGTGACTGAGG
CAGATGCGTTGAATATTTATAAAGCAGTGTATTGA

Upstream 100 bases:

>100_bases
ACTGGCTCACGCTGAACAGTAATATCCGTGCGCCTTGGGCCATTGCCACCTGTGCTAGCATGAAATTCACATTCCAATAT
GTTGATGGAGAAACACCATG

Downstream 100 bases:

>100_bases
TAAAAGAGGCGCAGCGCAGTCCTTAACACGCGCTGCTTTTGCAAGGATAAACCCATGAGTGATAAACCCAAACGCCCGCT
GCGCGAGGAGTATGGCTACC

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MGFEFATTHRVLVEVGAAKRLPELCQQLGGSRVMLVTDPGIRSTPLLKPVEDSFRTANMTLVIFDQVSADPADSVVLNAA
EQARDAGADLVIGFGGGSSMDVAKLVALLSHPKSSQQLSDIYGVGLATGPRLPLLQVPTTAGTGSEVTPVAIVTTGATTK
AGVVAPSLLPDLAVLDAELTLGLPPQVTAATGVDAMVHAIEAYTSAHKKNPYSDMLAREALRLLGGNLATAVKEGSNLAA
REACLLGAMMAGQAFANAPVAAVHALAYPLGGHFHIPHGLSNSLVLPEVLRFNLPKAAPLYAQLASILSDRPFADHEDGA
GVLIAALESLINEVGLPTKLREVGVSEDSLDVLASDAMLQQRLLVNNPREVTEADALNIYKAVY

Sequences:

>Translated_384_residues
MGFEFATTHRVLVEVGAAKRLPELCQQLGGSRVMLVTDPGIRSTPLLKPVEDSFRTANMTLVIFDQVSADPADSVVLNAA
EQARDAGADLVIGFGGGSSMDVAKLVALLSHPKSSQQLSDIYGVGLATGPRLPLLQVPTTAGTGSEVTPVAIVTTGATTK
AGVVAPSLLPDLAVLDAELTLGLPPQVTAATGVDAMVHAIEAYTSAHKKNPYSDMLAREALRLLGGNLATAVKEGSNLAA
REACLLGAMMAGQAFANAPVAAVHALAYPLGGHFHIPHGLSNSLVLPEVLRFNLPKAAPLYAQLASILSDRPFADHEDGA
GVLIAALESLINEVGLPTKLREVGVSEDSLDVLASDAMLQQRLLVNNPREVTEADALNIYKAVY
>Mature_383_residues
GFEFATTHRVLVEVGAAKRLPELCQQLGGSRVMLVTDPGIRSTPLLKPVEDSFRTANMTLVIFDQVSADPADSVVLNAAE
QARDAGADLVIGFGGGSSMDVAKLVALLSHPKSSQQLSDIYGVGLATGPRLPLLQVPTTAGTGSEVTPVAIVTTGATTKA
GVVAPSLLPDLAVLDAELTLGLPPQVTAATGVDAMVHAIEAYTSAHKKNPYSDMLAREALRLLGGNLATAVKEGSNLAAR
EACLLGAMMAGQAFANAPVAAVHALAYPLGGHFHIPHGLSNSLVLPEVLRFNLPKAAPLYAQLASILSDRPFADHEDGAG
VLIAALESLINEVGLPTKLREVGVSEDSLDVLASDAMLQQRLLVNNPREVTEADALNIYKAVY

Specific function: May act on the acetaldehyde produced from the degradation of ethanolamine [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=420, Percent_Identity=29.5238095238095, Blast_Score=135, Evalue=9e-32,
Organism=Escherichia coli, GI87082107, Length=369, Percent_Identity=36.3143631436314, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI48994951, Length=356, Percent_Identity=35.3932584269663, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1787493, Length=377, Percent_Identity=36.3395225464191, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1789163, Length=371, Percent_Identity=31.266846361186, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1789386, Length=360, Percent_Identity=26.6666666666667, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17537053, Length=372, Percent_Identity=28.2258064516129, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321181, Length=372, Percent_Identity=32.258064516129, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24657991, Length=409, Percent_Identity=31.0513447432763, Blast_Score=151, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: NA

Molecular weight: Translated: 39938; Mature: 39807

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFEFATTHRVLVEVGAAKRLPELCQQLGGSRVMLVTDPGIRSTPLLKPVEDSFRTANMT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHCCEE
LVIFDQVSADPADSVVLNAAEQARDAGADLVIGFGGGSSMDVAKLVALLSHPKSSQQLSD
EEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHH
IYGVGLATGPRLPLLQVPTTAGTGSEVTPVAIVTTGATTKAGVVAPSLLPDLAVLDAELT
HHHCCCCCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHCHHHHCCCCEE
LGLPPQVTAATGVDAMVHAIEAYTSAHKKNPYSDMLAREALRLLGGNLATAVKEGSNLAA
ECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHH
REACLLGAMMAGQAFANAPVAAVHALAYPLGGHFHIPHGLSNSLVLPEVLRFNLPKAAPL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHCCCCCCCHH
YAQLASILSDRPFADHEDGAGVLIAALESLINEVGLPTKLREVGVSEDSLDVLASDAMLQ
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHH
QRLLVNNPREVTEADALNIYKAVY
HHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GFEFATTHRVLVEVGAAKRLPELCQQLGGSRVMLVTDPGIRSTPLLKPVEDSFRTANMT
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHCCEE
LVIFDQVSADPADSVVLNAAEQARDAGADLVIGFGGGSSMDVAKLVALLSHPKSSQQLSD
EEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHH
IYGVGLATGPRLPLLQVPTTAGTGSEVTPVAIVTTGATTKAGVVAPSLLPDLAVLDAELT
HHHCCCCCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHCHHHHCCCCEE
LGLPPQVTAATGVDAMVHAIEAYTSAHKKNPYSDMLAREALRLLGGNLATAVKEGSNLAA
ECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHH
REACLLGAMMAGQAFANAPVAAVHALAYPLGGHFHIPHGLSNSLVLPEVLRFNLPKAAPL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHCCCCCCCHH
YAQLASILSDRPFADHEDGAGVLIAALESLINEVGLPTKLREVGVSEDSLDVLASDAMLQ
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHH
QRLLVNNPREVTEADALNIYKAVY
HHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7868611; 10464203; 11677609 [H]