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The map label for this gene is pabC [H]

Identifier: 110833933

GI number: 110833933

Start: 1214247

End: 1215059

Strand: Direct

Name: pabC [H]

Synonym: ABO_1072

Alternate gene names: 110833933

Gene position: 1214247-1215059 (Clockwise)

Preceding gene: 110833932

Following gene: 110833934

Centisome position: 38.92

GC content: 60.27

Gene sequence:

>813_bases
ATGCCACTAGACCCCCGTGATCGCGGCCTCGCTTACGGAGATGGTGTGTTTGAAACCGTGCGAGTGACCGCCTCCGGCAA
GTCGCCATTGTGGGCTCGCCATCGCGCCCGCTTGTATGGTGGGCTACAAACGCTGGGCATCGCACAACCCTCCGAGTCTA
CATTGCAGGCAGCACTGGATGCTGGCGTTGCGGCGCTAGGTGGCGAGCCGGGGGTAGTCAAACTCACGGTTACCCGTGGC
GTGGGTGGCAGGGGCTATTTGCCACCGCAATCGGCGCAGCCTACGGTTCTGTGGCAGACGAGCACTTTGCCAGAGTGGTC
TGAGCGACAACGCCGTGAAGGGTTAGCGCTGGGATTGTGCCAGACTCCTTTGTACCCTGATCCGTTGGCGGGCTACAAAC
ACCTTAACCGCCTTGCACAGGTAATGGCCCGCCGTGAAGTGGCACAGCAAGGGTGGGACGAAGGATTGCTACTCAGCACC
CGTCGTCAGCCCTTGGAGGCTACGTCCATGAATCTCTTTGCCCGCTTCGCCGATCACTGGTGGATGCCTGATTTGGCTGC
AGCGGGTGCCGGTGTGGAGGGCGTTATGCAAGGCCACTTGCGTGATACGCTGCGCCATGGCGGTGAAAAAGTGGTCTGCG
ATCTGCGGCCACTGTCACAGCTGCGTACTGCCGAAGGCCTGTTTTTGTGTAACAGTGTTGTCGGCGTGCTCGCGGTGCGT
AAACTGGCGCAATGGCATTGGCCGGTGTTGGCATCGGTCCGGGAACTGCAACAGTCGACAGAAACCTTTTTGGCCGGCTC
ACTGAAGGGCTAA

Upstream 100 bases:

>100_bases
TCGTGGCAAATCAGGCTCAGGAACGCACCATCAACTACGCGCTGTCCAATTCCTTTGGTTTTGGTGGTACTAACGGCACC
TTGCTGTTCAAGAAGGTGTA

Downstream 100 bases:

>100_bases
TAACCCCACTATGCGTAAAAAAATCCGTATTTTTGGACTGTTGGTTGTCCTACTGATAGTCGCTGTTCCTGTGGCGGGGG
CCTGGGTCAGTAGTTATCTA

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MPLDPRDRGLAYGDGVFETVRVTASGKSPLWARHRARLYGGLQTLGIAQPSESTLQAALDAGVAALGGEPGVVKLTVTRG
VGGRGYLPPQSAQPTVLWQTSTLPEWSERQRREGLALGLCQTPLYPDPLAGYKHLNRLAQVMARREVAQQGWDEGLLLST
RRQPLEATSMNLFARFADHWWMPDLAAAGAGVEGVMQGHLRDTLRHGGEKVVCDLRPLSQLRTAEGLFLCNSVVGVLAVR
KLAQWHWPVLASVRELQQSTETFLAGSLKG

Sequences:

>Translated_270_residues
MPLDPRDRGLAYGDGVFETVRVTASGKSPLWARHRARLYGGLQTLGIAQPSESTLQAALDAGVAALGGEPGVVKLTVTRG
VGGRGYLPPQSAQPTVLWQTSTLPEWSERQRREGLALGLCQTPLYPDPLAGYKHLNRLAQVMARREVAQQGWDEGLLLST
RRQPLEATSMNLFARFADHWWMPDLAAAGAGVEGVMQGHLRDTLRHGGEKVVCDLRPLSQLRTAEGLFLCNSVVGVLAVR
KLAQWHWPVLASVRELQQSTETFLAGSLKG
>Mature_269_residues
PLDPRDRGLAYGDGVFETVRVTASGKSPLWARHRARLYGGLQTLGIAQPSESTLQAALDAGVAALGGEPGVVKLTVTRGV
GGRGYLPPQSAQPTVLWQTSTLPEWSERQRREGLALGLCQTPLYPDPLAGYKHLNRLAQVMARREVAQQGWDEGLLLSTR
RQPLEATSMNLFARFADHWWMPDLAAAGAGVEGVMQGHLRDTLRHGGEKVVCDLRPLSQLRTAEGLFLCNSVVGVLAVRK
LAQWHWPVLASVRELQQSTETFLAGSLKG

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=234, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 29389; Mature: 29258

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLDPRDRGLAYGDGVFETVRVTASGKSPLWARHRARLYGGLQTLGIAQPSESTLQAALD
CCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHH
AGVAALGGEPGVVKLTVTRGVGGRGYLPPQSAQPTVLWQTSTLPEWSERQRREGLALGLC
HHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCEEEEE
QTPLYPDPLAGYKHLNRLAQVMARREVAQQGWDEGLLLSTRRQPLEATSMNLFARFADHW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHC
WMPDLAAAGAGVEGVMQGHLRDTLRHGGEKVVCDLRPLSQLRTAEGLFLCNSVVGVLAVR
CCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
KLAQWHWPVLASVRELQQSTETFLAGSLKG
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PLDPRDRGLAYGDGVFETVRVTASGKSPLWARHRARLYGGLQTLGIAQPSESTLQAALD
CCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHH
AGVAALGGEPGVVKLTVTRGVGGRGYLPPQSAQPTVLWQTSTLPEWSERQRREGLALGLC
HHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCEEEEE
QTPLYPDPLAGYKHLNRLAQVMARREVAQQGWDEGLLLSTRRQPLEATSMNLFARFADHW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHC
WMPDLAAAGAGVEGVMQGHLRDTLRHGGEKVVCDLRPLSQLRTAEGLFLCNSVVGVLAVR
CCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
KLAQWHWPVLASVRELQQSTETFLAGSLKG
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]