| Definition | Alcanivorax borkumensis SK2 chromosome, complete genome. |
|---|---|
| Accession | NC_008260 |
| Length | 3,120,143 |
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The map label for this gene is pbpC [H]
Identifier: 110833761
GI number: 110833761
Start: 1003490
End: 1005775
Strand: Direct
Name: pbpC [H]
Synonym: ABO_0900
Alternate gene names: 110833761
Gene position: 1003490-1005775 (Clockwise)
Preceding gene: 110833760
Following gene: 110833762
Centisome position: 32.16
GC content: 64.04
Gene sequence:
>2286_bases ATGGTGGTCGCGTTGCAGTTCTGGCCATTGCCCGAGCGGCTAACCCACACTCCGTACGCCACCCTGATGCTGGACCGCAA TGATCGCTTGCTCGGGGCGCGTATTGCCGCAGATGAGCAGTGGCGCTTCGTTCCGGTGGAGGTGTTGCCGGACAAATACC GCCGCGCCTTGCTGAGTTACGAAGACAAGCGCTTCTTCGCTCACCCCGGGGTCGATCCGCTGGCGATTGCTCGGGCTGCC TGGCTCAATGCCCGTGCCGGCCGCGTGGTTAGCGGTGGCTCCACGCTGACCATGCAGCTGGCCCGGCTGCTGCGTGATGA CCCGCCCAGAACACTGCCAGAGAAGGCCCGCGAGGCGCTGTTGGCGCTGCAGCTGGAATGGCACTTCAGCAAGGATGAGC TGCTAATCCAGTACGCTAGCCGGGCTCCCTTTGGGGGCAATATTGTGGGGTTACGCGCCGCCGCTTGGCGTTACTTTGGC CGGGAACCGGCGGCGTTGAGCTGGGCGGAAGCGGCGTTGTTGGCGGTGCTGCCCAATGCCCCCTCATTGATCCACCCGGG GCGAAACCGGGAACGATTACGGGCCAAGCGCAATGGGTTGCTCAATGACCTGCACGAGAGCGGAGCACTGCCGGCCAGGG ACCTGCAACTGGCACTGCTGGAACCTTTGCCCGCTGCCCCCAAGGCGTTGCCCGCTAACGCCAACCACCTGCTGAACTCT CTCACCGTCAGTAGCGAACAACACCTGTTCCGCACTACTTTGGATGCAGACCTGCAGCACCGGGTGCGCGAGCTGGCGCG CCGGCATGGTCGGCGCTTAGCCGGGGAGGGCGTGCATAATGTGGCGGTGGTGGTGATTGATCACATCGAGTTGGCCACCC GCGCCTACGTGGGCAACATGACCCACGGCGATGCCCGCGAATACGGTGCCGCCGTGGATATCGCCAGTGCGCCGCGCTCC ACGGGCAGCGTACTCAAGCCCTTGTTATATGGCCTGATGCTGGACGATGGGTTGTTGCTGCCCGATACGCTGGTGCCGGA TTTGCCTACCAATTATGGCGGCTTCAGCCCGGAAAATTTCGACCATGGCTACCGGGGCGCTGTCCCTGCCCATCAGGCGC TCAGTCAGTCCCTGAACATTCCCGCCGTGCGCATGCTGCGCGAATACGGGGTGGGGCGTTTCCATAACCAGCTGCAGCGC ATGGGTATGACCACCCTGTTTCGTAACGCTGAAGATTACGGCCTCACCCTGGTGCTGGGTGGAGCAGAGGGGGCGCTTAA CGAACTCACGGGTATTTACGCACGGCTGTTTGCTAGCGCCCGGCAGGCACCGGCTTACCCCGTGGCGGTGTTGCAATCCT CCCTTGCCAATAGAGAGCCCGGCAGGGCGCAGCCCAGCCCTGTTCTTAGCCCCGGCGCTGCTTGGTTAACCCTGGATGCC CTGCGCCAGGTGGCACGGCCCGGCACCGCCCGGCAATGGCGGTTGTTCAGCTCCAGCCAAGCCATCGCCTGGAAAACCGG TACCAGCTATGGCCTGCGCGATGCCTGGGCTATCGGCAGTAATGGCCGCTACACCGTGGGCGTGTGGGCGGGCAACGGCA ACGGTGAGCCGGCTCCTAGCCTGGGCGGCGCGGCCACTGCAGCGCCGTTGATGTTGGACGCGTTCAGCCTGCTGGGGCCG GCTCGCTGGCCAGAGGCGCCCTTGGCTGATTTGAAAACCGTGCATGTGTGCAGTGACGACGGTTATCTGGCCGGGGGGCG TTGCCCCACGGTGGAGCGGCAGGCGCCGCTGCACAGCCATTTCGAAACCGTCACGCCGTACCATGTGCGGGTGCATTTGG ATAACAATGGCCAGCGGGTGCATAGCCAGTGCGAGCCGGTAAGCGCCATGCGTCATCGCGATTGGTTTGTGCTGCCTCCC GGTCAGGCCTGGTTCTACCAGCGCCGCCACCCGCACTACCGGCCGTTGCCCAGCTGGCGGGAGGATTGCTTAGCGGGGGC TCGGGCCATGGATAGCGAGCCGCCCATGGCACTGATCTACCCCCATGCGGGCACCGCCATTTATATTCCGGTGGAGCTGA ATGGTCGGCTGGGCCGGGCGGTGTTGCGCGCGGTGCACCAGCGCGCCGATGCCACCCTGTATTGGCACCTGGATGCCACT TACTTAGGGGAAACCCGCCATTTTCACGAATGGGCGCTCATCGCCGAGCCCGGCTGGCATACCCTCACGTTGGTGGATGA TCAGGGGTTTCGGTTAAAGCAGCGCTTCAAGGTGTTGGGCAAATAA
Upstream 100 bases:
>100_bases GGCGTAGCCGTAACCCGATACAGGCTTTTGCAACCGGCCCCCACCCGCGATGAAATTTCTGCGCCGTTCAATTCTTACCC TGCTGATTATCGCTGTGCCT
Downstream 100 bases:
>100_bases ATCACCTTTACTGCCAGATTACGCCTTTTCAGGTCCTCGGAGCCCTTGGGTACATTCCGCCGATAAAACCCTATATTCAC CGCGCCTTTTCTTCGCGAAT
Product: penicillin-binding protein 1C
Products: NA
Alternate protein names: PBP-1c; PBP1c; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Transpeptidase-like module [H]
Number of amino acids: Translated: 761; Mature: 761
Protein sequence:
>761_residues MVVALQFWPLPERLTHTPYATLMLDRNDRLLGARIAADEQWRFVPVEVLPDKYRRALLSYEDKRFFAHPGVDPLAIARAA WLNARAGRVVSGGSTLTMQLARLLRDDPPRTLPEKAREALLALQLEWHFSKDELLIQYASRAPFGGNIVGLRAAAWRYFG REPAALSWAEAALLAVLPNAPSLIHPGRNRERLRAKRNGLLNDLHESGALPARDLQLALLEPLPAAPKALPANANHLLNS LTVSSEQHLFRTTLDADLQHRVRELARRHGRRLAGEGVHNVAVVVIDHIELATRAYVGNMTHGDAREYGAAVDIASAPRS TGSVLKPLLYGLMLDDGLLLPDTLVPDLPTNYGGFSPENFDHGYRGAVPAHQALSQSLNIPAVRMLREYGVGRFHNQLQR MGMTTLFRNAEDYGLTLVLGGAEGALNELTGIYARLFASARQAPAYPVAVLQSSLANREPGRAQPSPVLSPGAAWLTLDA LRQVARPGTARQWRLFSSSQAIAWKTGTSYGLRDAWAIGSNGRYTVGVWAGNGNGEPAPSLGGAATAAPLMLDAFSLLGP ARWPEAPLADLKTVHVCSDDGYLAGGRCPTVERQAPLHSHFETVTPYHVRVHLDNNGQRVHSQCEPVSAMRHRDWFVLPP GQAWFYQRRHPHYRPLPSWREDCLAGARAMDSEPPMALIYPHAGTAIYIPVELNGRLGRAVLRAVHQRADATLYWHLDAT YLGETRHFHEWALIAEPGWHTLTLVDDQGFRLKQRFKVLGK
Sequences:
>Translated_761_residues MVVALQFWPLPERLTHTPYATLMLDRNDRLLGARIAADEQWRFVPVEVLPDKYRRALLSYEDKRFFAHPGVDPLAIARAA WLNARAGRVVSGGSTLTMQLARLLRDDPPRTLPEKAREALLALQLEWHFSKDELLIQYASRAPFGGNIVGLRAAAWRYFG REPAALSWAEAALLAVLPNAPSLIHPGRNRERLRAKRNGLLNDLHESGALPARDLQLALLEPLPAAPKALPANANHLLNS LTVSSEQHLFRTTLDADLQHRVRELARRHGRRLAGEGVHNVAVVVIDHIELATRAYVGNMTHGDAREYGAAVDIASAPRS TGSVLKPLLYGLMLDDGLLLPDTLVPDLPTNYGGFSPENFDHGYRGAVPAHQALSQSLNIPAVRMLREYGVGRFHNQLQR MGMTTLFRNAEDYGLTLVLGGAEGALNELTGIYARLFASARQAPAYPVAVLQSSLANREPGRAQPSPVLSPGAAWLTLDA LRQVARPGTARQWRLFSSSQAIAWKTGTSYGLRDAWAIGSNGRYTVGVWAGNGNGEPAPSLGGAATAAPLMLDAFSLLGP ARWPEAPLADLKTVHVCSDDGYLAGGRCPTVERQAPLHSHFETVTPYHVRVHLDNNGQRVHSQCEPVSAMRHRDWFVLPP GQAWFYQRRHPHYRPLPSWREDCLAGARAMDSEPPMALIYPHAGTAIYIPVELNGRLGRAVLRAVHQRADATLYWHLDAT YLGETRHFHEWALIAEPGWHTLTLVDDQGFRLKQRFKVLGK >Mature_761_residues MVVALQFWPLPERLTHTPYATLMLDRNDRLLGARIAADEQWRFVPVEVLPDKYRRALLSYEDKRFFAHPGVDPLAIARAA WLNARAGRVVSGGSTLTMQLARLLRDDPPRTLPEKAREALLALQLEWHFSKDELLIQYASRAPFGGNIVGLRAAAWRYFG REPAALSWAEAALLAVLPNAPSLIHPGRNRERLRAKRNGLLNDLHESGALPARDLQLALLEPLPAAPKALPANANHLLNS LTVSSEQHLFRTTLDADLQHRVRELARRHGRRLAGEGVHNVAVVVIDHIELATRAYVGNMTHGDAREYGAAVDIASAPRS TGSVLKPLLYGLMLDDGLLLPDTLVPDLPTNYGGFSPENFDHGYRGAVPAHQALSQSLNIPAVRMLREYGVGRFHNQLQR MGMTTLFRNAEDYGLTLVLGGAEGALNELTGIYARLFASARQAPAYPVAVLQSSLANREPGRAQPSPVLSPGAAWLTLDA LRQVARPGTARQWRLFSSSQAIAWKTGTSYGLRDAWAIGSNGRYTVGVWAGNGNGEPAPSLGGAATAAPLMLDAFSLLGP ARWPEAPLADLKTVHVCSDDGYLAGGRCPTVERQAPLHSHFETVTPYHVRVHLDNNGQRVHSQCEPVSAMRHRDWFVLPP GQAWFYQRRHPHYRPLPSWREDCLAGARAMDSEPPMALIYPHAGTAIYIPVELNGRLGRAVLRAVHQRADATLYWHLDAT YLGETRHFHEWALIAEPGWHTLTLVDDQGFRLKQRFKVLGK
Specific function: Cell wall formation. The enzyme has a penicillin- insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a transpeptidase C-terminal domain which may not be functional [H]
COG id: COG4953
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein PbpC
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1788867, Length=791, Percent_Identity=34.7661188369153, Blast_Score=379, Evalue=1e-106, Organism=Escherichia coli, GI1786343, Length=593, Percent_Identity=27.318718381113, Blast_Score=138, Evalue=1e-33, Organism=Escherichia coli, GI87082258, Length=196, Percent_Identity=35.7142857142857, Blast_Score=115, Evalue=1e-26, Organism=Escherichia coli, GI1789601, Length=199, Percent_Identity=30.6532663316583, Blast_Score=74, Evalue=4e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011815 - InterPro: IPR009647 - InterPro: IPR001460 [H]
Pfam domain/function: PF06832 BiPBP_C; PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-
Molecular weight: Translated: 84081; Mature: 84081
Theoretical pI: Translated: 9.59; Mature: 9.59
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVVALQFWPLPERLTHTPYATLMLDRNDRLLGARIAADEQWRFVPVEVLPDKYRRALLSY CEEEEEECCCCHHHCCCCEEEEEECCCCCEEEEEECCCCCEEEEEHEECCHHHHHHHHCC EDKRFFAHPGVDPLAIARAAWLNARAGRVVSGGSTLTMQLARLLRDDPPRTLPEKAREAL CCCEEEECCCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHH LALQLEWHFSKDELLIQYASRAPFGGNIVGLRAAAWRYFGREPAALSWAEAALLAVLPNA EEEEEEECCCCCHHHHEEHHCCCCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHEECCCC PSLIHPGRNRERLRAKRNGLLNDLHESGALPARDLQLALLEPLPAAPKALPANANHLLNS CCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCHHCCHHEEECCCCCCCCCCCCCHHHHHHH LTVSSEQHLFRTTLDADLQHRVRELARRHGRRLAGEGVHNVAVVVIDHIELATRAYVGNM HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHHHCCC THGDAREYGAAVDIASAPRSTGSVLKPLLYGLMLDDGLLLPDTLVPDLPTNYGGFSPENF CCCCHHHHCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCC DHGYRGAVPAHQALSQSLNIPAVRMLREYGVGRFHNQLQRMGMTTLFRNAEDYGLTLVLG CCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCHHHHHCCCCCCCEEEEEE GAEGALNELTGIYARLFASARQAPAYPVAVLQSSLANREPGRAQPSPVLSPGAAWLTLDA CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH LRQVARPGTARQWRLFSSSQAIAWKTGTSYGLRDAWAIGSNGRYTVGVWAGNGNGEPAPS HHHHHCCCCCCEEEEECCCCEEEEECCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCC LGGAATAAPLMLDAFSLLGPARWPEAPLADLKTVHVCSDDGYLAGGRCPTVERQAPLHSH CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCHHH FETVTPYHVRVHLDNNGQRVHSQCEPVSAMRHRDWFVLPPGQAWFYQRRHPHYRPLPSWR HCCCCCEEEEEEECCCCHHHHHHCCHHHHHHCCCEEEECCCHHHHHHCCCCCCCCCCCHH EDCLAGARAMDSEPPMALIYPHAGTAIYIPVELNGRLGRAVLRAVHQRADATLYWHLDAT HHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEEE YLGETRHFHEWALIAEPGWHTLTLVDDQGFRLKQRFKVLGK EECCCCCEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHCC >Mature Secondary Structure MVVALQFWPLPERLTHTPYATLMLDRNDRLLGARIAADEQWRFVPVEVLPDKYRRALLSY CEEEEEECCCCHHHCCCCEEEEEECCCCCEEEEEECCCCCEEEEEHEECCHHHHHHHHCC EDKRFFAHPGVDPLAIARAAWLNARAGRVVSGGSTLTMQLARLLRDDPPRTLPEKAREAL CCCEEEECCCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHH LALQLEWHFSKDELLIQYASRAPFGGNIVGLRAAAWRYFGREPAALSWAEAALLAVLPNA EEEEEEECCCCCHHHHEEHHCCCCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHEECCCC PSLIHPGRNRERLRAKRNGLLNDLHESGALPARDLQLALLEPLPAAPKALPANANHLLNS CCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCHHCCHHEEECCCCCCCCCCCCCHHHHHHH LTVSSEQHLFRTTLDADLQHRVRELARRHGRRLAGEGVHNVAVVVIDHIELATRAYVGNM HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHHHCCC THGDAREYGAAVDIASAPRSTGSVLKPLLYGLMLDDGLLLPDTLVPDLPTNYGGFSPENF CCCCHHHHCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCC DHGYRGAVPAHQALSQSLNIPAVRMLREYGVGRFHNQLQRMGMTTLFRNAEDYGLTLVLG CCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCHHHHHCCCCCCCEEEEEE GAEGALNELTGIYARLFASARQAPAYPVAVLQSSLANREPGRAQPSPVLSPGAAWLTLDA CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH LRQVARPGTARQWRLFSSSQAIAWKTGTSYGLRDAWAIGSNGRYTVGVWAGNGNGEPAPS HHHHHCCCCCCEEEEECCCCEEEEECCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCC LGGAATAAPLMLDAFSLLGPARWPEAPLADLKTVHVCSDDGYLAGGRCPTVERQAPLHSH CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCHHH FETVTPYHVRVHLDNNGQRVHSQCEPVSAMRHRDWFVLPPGQAWFYQRRHPHYRPLPSWR HCCCCCEEEEEEECCCCHHHHHHCCHHHHHHCCCEEEECCCHHHHHHCCCCCCCCCCCHH EDCLAGARAMDSEPPMALIYPHAGTAIYIPVELNGRLGRAVLRAVHQRADATLYWHLDAT HHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEEE YLGETRHFHEWALIAEPGWHTLTLVDDQGFRLKQRFKVLGK EECCCCCEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10542235; 9205837; 9278503; 9841666 [H]