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The map label for this gene is tsaA [H]

Identifier: 110833584

GI number: 110833584

Start: 813876

End: 814478

Strand: Direct

Name: tsaA [H]

Synonym: ABO_0723

Alternate gene names: 110833584

Gene position: 813876-814478 (Clockwise)

Preceding gene: 110833583

Following gene: 110833586

Centisome position: 26.08

GC content: 54.73

Gene sequence:

>603_bases
ATGGGCGTTCTGGTAGGTAAACCTGCACCGGATTTTACTGTTCCTGCTGTATTGGGCGATGGCAGCATCGTTGATGAGTT
CACCCTGTCTGAAGCCATTAAAGGCAAGTATGGCCTGGTGTTCTTCTACCCGCTGGACTTCACCTTCGTGTGCCCGTCCG
AGCTAATTGCTCTGGATCATCGCATGGACGCGTTCAAAGAACGCAACGTGGAAGTGATTGGCGTTTCCATCGATAGTCAT
TTTACTCACAACGCATGGCGCAACACGCCGGTTAACGATGGCGGCATCGGCCCAGTGAAATACACCCTGGCCGCAGACAT
GAACCACGGTATTGCCCAGTCCTATGACGTTGAGTCCGAAGGCGGTATGGCTTTCCGTGGTGTGTTCCTGATCGATCAAA
ACGGTGTCGTGCGCAGCCAGATCGTTAACGATCTGCCACTGGGTCGTAACATGGACGAGCTGATTCGTCTGGTTGATGCC
CTGCAGTTCCACGAAGAGCACGGTGAAGTGTGCCCGGCGGGCTGGCAGAAAGGCGATTCCGGTATGAAGGACACCCCGGA
CGGCGTGGCCGAGTACCTGTCTGGTAATGCCGACAAACTGTAA

Upstream 100 bases:

>100_bases
TGCCATGGGCGTTGTATGATCTGCTGCACTGATTTCAAGCGGCCAGAGAGATGGCACTGCTCTGGCTATATCGTATAAAT
GGAAACAATGGAGAGAAACA

Downstream 100 bases:

>100_bases
TAATAAGCCGCACAAAGAAAAGGGGCGCTAGAAATAGCGCCCCTTTTTTATGCTGTTTTCTGGATGCTTGAAGCTGGATG
ACTGGCGTTAAAATCTAGAT

Product: oxidoreductase

Products: NA

Alternate protein names: 26 kDa antigen; Thioredoxin reductase [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MGVLVGKPAPDFTVPAVLGDGSIVDEFTLSEAIKGKYGLVFFYPLDFTFVCPSELIALDHRMDAFKERNVEVIGVSIDSH
FTHNAWRNTPVNDGGIGPVKYTLAADMNHGIAQSYDVESEGGMAFRGVFLIDQNGVVRSQIVNDLPLGRNMDELIRLVDA
LQFHEEHGEVCPAGWQKGDSGMKDTPDGVAEYLSGNADKL

Sequences:

>Translated_200_residues
MGVLVGKPAPDFTVPAVLGDGSIVDEFTLSEAIKGKYGLVFFYPLDFTFVCPSELIALDHRMDAFKERNVEVIGVSIDSH
FTHNAWRNTPVNDGGIGPVKYTLAADMNHGIAQSYDVESEGGMAFRGVFLIDQNGVVRSQIVNDLPLGRNMDELIRLVDA
LQFHEEHGEVCPAGWQKGDSGMKDTPDGVAEYLSGNADKL
>Mature_199_residues
GVLVGKPAPDFTVPAVLGDGSIVDEFTLSEAIKGKYGLVFFYPLDFTFVCPSELIALDHRMDAFKERNVEVIGVSIDSHF
THNAWRNTPVNDGGIGPVKYTLAADMNHGIAQSYDVESEGGMAFRGVFLIDQNGVVRSQIVNDLPLGRNMDELIRLVDAL
QFHEEHGEVCPAGWQKGDSGMKDTPDGVAEYLSGNADKL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4505591, Length=191, Percent_Identity=51.3089005235602, Blast_Score=202, Evalue=1e-52,
Organism=Homo sapiens, GI32455266, Length=191, Percent_Identity=51.3089005235602, Blast_Score=202, Evalue=1e-52,
Organism=Homo sapiens, GI32455264, Length=191, Percent_Identity=51.3089005235602, Blast_Score=202, Evalue=1e-52,
Organism=Homo sapiens, GI32189392, Length=191, Percent_Identity=51.8324607329843, Blast_Score=201, Evalue=3e-52,
Organism=Homo sapiens, GI5453549, Length=190, Percent_Identity=46.8421052631579, Blast_Score=184, Evalue=5e-47,
Organism=Homo sapiens, GI5802974, Length=161, Percent_Identity=49.6894409937888, Blast_Score=178, Evalue=3e-45,
Organism=Homo sapiens, GI32483377, Length=161, Percent_Identity=49.6894409937888, Blast_Score=177, Evalue=4e-45,
Organism=Homo sapiens, GI33188454, Length=82, Percent_Identity=57.3170731707317, Blast_Score=94, Evalue=5e-20,
Organism=Homo sapiens, GI4758638, Length=191, Percent_Identity=29.3193717277487, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI1786822, Length=160, Percent_Identity=33.75, Blast_Score=112, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193204376, Length=194, Percent_Identity=48.9690721649485, Blast_Score=182, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI32565831, Length=192, Percent_Identity=49.4791666666667, Blast_Score=182, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17554494, Length=188, Percent_Identity=45.7446808510638, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25153706, Length=179, Percent_Identity=29.0502793296089, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323613, Length=196, Percent_Identity=42.8571428571429, Blast_Score=160, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320661, Length=191, Percent_Identity=41.3612565445026, Blast_Score=149, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6319407, Length=180, Percent_Identity=30, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24656348, Length=194, Percent_Identity=49.4845360824742, Blast_Score=196, Evalue=9e-51,
Organism=Drosophila melanogaster, GI17864676, Length=194, Percent_Identity=49.4845360824742, Blast_Score=196, Evalue=9e-51,
Organism=Drosophila melanogaster, GI17738015, Length=187, Percent_Identity=47.0588235294118, Blast_Score=183, Evalue=5e-47,
Organism=Drosophila melanogaster, GI17157991, Length=192, Percent_Identity=45.8333333333333, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24641739, Length=192, Percent_Identity=45.8333333333333, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI21357347, Length=191, Percent_Identity=43.455497382199, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24581278, Length=185, Percent_Identity=27.5675675675676, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17975518, Length=160, Percent_Identity=29.375, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21774; Mature: 21643

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVLVGKPAPDFTVPAVLGDGSIVDEFTLSEAIKGKYGLVFFYPLDFTFVCPSELIALDH
CCEECCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCEEEEECCCEEEECCHHHHHHHH
RMDAFKERNVEVIGVSIDSHFTHNAWRNTPVNDGGIGPVKYTLAADMNHGIAQSYDVESE
HHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCC
GGMAFRGVFLIDQNGVVRSQIVNDLPLGRNMDELIRLVDALQFHEEHGEVCPAGWQKGDS
CCEEEEEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GMKDTPDGVAEYLSGNADKL
CCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GVLVGKPAPDFTVPAVLGDGSIVDEFTLSEAIKGKYGLVFFYPLDFTFVCPSELIALDH
CEECCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCEEEEECCCEEEECCHHHHHHHH
RMDAFKERNVEVIGVSIDSHFTHNAWRNTPVNDGGIGPVKYTLAADMNHGIAQSYDVESE
HHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCC
GGMAFRGVFLIDQNGVVRSQIVNDLPLGRNMDELIRLVDALQFHEEHGEVCPAGWQKGDS
CCEEEEEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GMKDTPDGVAEYLSGNADKL
CCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682; 1987145 [H]