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The map label for this gene is ahpC [C]

Identifier: 110833569

GI number: 110833569

Start: 790792

End: 791445

Strand: Direct

Name: ahpC [C]

Synonym: ABO_0708

Alternate gene names: 110833569

Gene position: 790792-791445 (Clockwise)

Preceding gene: 110833566

Following gene: 110833573

Centisome position: 25.34

GC content: 55.66

Gene sequence:

>654_bases
ATGGAAGCCCCAGTACAGCAAACCCGCGGCCTGCCGCAGATCAATGAACCGGCCCCCAATTTCAACGCACTGACCACCGA
TGGCCAGAGAACCCTGGCAGATTATCGTGGTAAGTGGTTGGTGCTATTTTCCCGCCCGGCGGACTTTACCCCGGTGTGCA
CCACCGAATTCATGGCCTTTGCCAAGGCCGCCCCAGAATTTGCCAAGCGCAACGGTGAACTGCTTGGCTTGTCTATCGGC
AGCATCCACTCGCACATTGCCTGGATACGCAATATCAAACAGAACTTCGGTGTGGAGATCCCTTTCCCGATCATTGAAGA
CCTGAAGATGGAAGTGGCCAATGCTTACGGAATGATCCATCCGGGCGCAGCGGATACCTCTGCCGTGCGCGCCACCTTTA
TCATCGACCCTAATGGCATCCTGCGTGCCATGGTTTATTACCCGATGAGTAATGGTCGCTCCATTCCCGAATTCCTGCGC
CTGCTAGAAGCACTGCAAACCAGTGATGAAAACGGCATCGCCACCCCGGAAGGTTGGCAGCCAGGAGACAAGGTCATCGT
CCCGCCGGCCAAGACCGCGCAAGCGGCCAACGCCCGTGTAGAGTCAGGTGAATACGACTGCAAGGATTTCTACTTCTGCA
CCAAATCTTTGTAA

Upstream 100 bases:

>100_bases
ATCTAAACCATATAAGAATATATATTTCAGGAATACGGTCTCCCTTTTATGCTTTTTCTGCAAGCCCGGTCCCCCGCTTT
TAATGCAAGGAGAGAGACCA

Downstream 100 bases:

>100_bases
GCTGAGCAAAACGCCCAGCGCCACCATCCGGTGGCGCTCCTCTTTCTCCTTCTTGCCCTTCATTCAAGCTGAATCGCCAG
AATCTGGCTGTCGGAAAATC

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MEAPVQQTRGLPQINEPAPNFNALTTDGQRTLADYRGKWLVLFSRPADFTPVCTTEFMAFAKAAPEFAKRNGELLGLSIG
SIHSHIAWIRNIKQNFGVEIPFPIIEDLKMEVANAYGMIHPGAADTSAVRATFIIDPNGILRAMVYYPMSNGRSIPEFLR
LLEALQTSDENGIATPEGWQPGDKVIVPPAKTAQAANARVESGEYDCKDFYFCTKSL

Sequences:

>Translated_217_residues
MEAPVQQTRGLPQINEPAPNFNALTTDGQRTLADYRGKWLVLFSRPADFTPVCTTEFMAFAKAAPEFAKRNGELLGLSIG
SIHSHIAWIRNIKQNFGVEIPFPIIEDLKMEVANAYGMIHPGAADTSAVRATFIIDPNGILRAMVYYPMSNGRSIPEFLR
LLEALQTSDENGIATPEGWQPGDKVIVPPAKTAQAANARVESGEYDCKDFYFCTKSL
>Mature_217_residues
MEAPVQQTRGLPQINEPAPNFNALTTDGQRTLADYRGKWLVLFSRPADFTPVCTTEFMAFAKAAPEFAKRNGELLGLSIG
SIHSHIAWIRNIKQNFGVEIPFPIIEDLKMEVANAYGMIHPGAADTSAVRATFIIDPNGILRAMVYYPMSNGRSIPEFLR
LLEALQTSDENGIATPEGWQPGDKVIVPPAKTAQAANARVESGEYDCKDFYFCTKSL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=201, Percent_Identity=39.8009950248756, Blast_Score=146, Evalue=1e-35,
Organism=Homo sapiens, GI4505591, Length=193, Percent_Identity=38.860103626943, Blast_Score=138, Evalue=5e-33,
Organism=Homo sapiens, GI32455266, Length=193, Percent_Identity=38.860103626943, Blast_Score=138, Evalue=5e-33,
Organism=Homo sapiens, GI32455264, Length=193, Percent_Identity=38.860103626943, Blast_Score=138, Evalue=5e-33,
Organism=Homo sapiens, GI32189392, Length=184, Percent_Identity=39.1304347826087, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI5453549, Length=181, Percent_Identity=38.6740331491713, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI5802974, Length=189, Percent_Identity=35.978835978836, Blast_Score=121, Evalue=4e-28,
Organism=Homo sapiens, GI32483377, Length=166, Percent_Identity=37.9518072289157, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI33188454, Length=83, Percent_Identity=45.7831325301205, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1786822, Length=161, Percent_Identity=29.8136645962733, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25153706, Length=209, Percent_Identity=35.8851674641148, Blast_Score=133, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI193204376, Length=186, Percent_Identity=38.1720430107527, Blast_Score=127, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI32565831, Length=186, Percent_Identity=38.1720430107527, Blast_Score=127, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17554494, Length=162, Percent_Identity=34.5679012345679, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6319407, Length=197, Percent_Identity=47.2081218274112, Blast_Score=172, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6323613, Length=189, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6320661, Length=189, Percent_Identity=32.8042328042328, Blast_Score=103, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17975518, Length=202, Percent_Identity=39.6039603960396, Blast_Score=147, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24652434, Length=202, Percent_Identity=39.6039603960396, Blast_Score=147, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24652436, Length=202, Percent_Identity=39.6039603960396, Blast_Score=146, Evalue=9e-36,
Organism=Drosophila melanogaster, GI24581278, Length=188, Percent_Identity=37.7659574468085, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17738015, Length=174, Percent_Identity=39.0804597701149, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21357347, Length=186, Percent_Identity=40.8602150537634, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17157991, Length=192, Percent_Identity=38.5416666666667, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24641739, Length=192, Percent_Identity=38.5416666666667, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24656348, Length=189, Percent_Identity=35.4497354497354, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17864676, Length=189, Percent_Identity=35.4497354497354, Blast_Score=126, Evalue=1e-29,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23908; Mature: 23908

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAPVQQTRGLPQINEPAPNFNALTTDGQRTLADYRGKWLVLFSRPADFTPVCTTEFMAF
CCCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHH
AKAAPEFAKRNGELLGLSIGSIHSHIAWIRNIKQNFGVEIPFPIIEDLKMEVANAYGMIH
HHHCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
PGAADTSAVRATFIIDPNGILRAMVYYPMSNGRSIPEFLRLLEALQTSDENGIATPEGWQ
CCCCCCCCEEEEEEECCCHHEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
PGDKVIVPPAKTAQAANARVESGEYDCKDFYFCTKSL
CCCEEEECCCCHHHHHCCCCCCCCCCCHHHEEEECCC
>Mature Secondary Structure
MEAPVQQTRGLPQINEPAPNFNALTTDGQRTLADYRGKWLVLFSRPADFTPVCTTEFMAF
CCCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHH
AKAAPEFAKRNGELLGLSIGSIHSHIAWIRNIKQNFGVEIPFPIIEDLKMEVANAYGMIH
HHHCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
PGAADTSAVRATFIIDPNGILRAMVYYPMSNGRSIPEFLRLLEALQTSDENGIATPEGWQ
CCCCCCCCEEEEEEECCCHHEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
PGDKVIVPPAKTAQAANARVESGEYDCKDFYFCTKSL
CCCEEEECCCCHHHHHCCCCCCCCCCCHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]