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The map label for this gene is rstA [H]

Identifier: 110833573

GI number: 110833573

Start: 799169

End: 799891

Strand: Direct

Name: rstA [H]

Synonym: ABO_0712

Alternate gene names: 110833573

Gene position: 799169-799891 (Clockwise)

Preceding gene: 110833569

Following gene: 110833574

Centisome position: 25.61

GC content: 53.53

Gene sequence:

>723_bases
ATGACAACTGTGCAGGATAACCCGCCAGCCATCATGATCGTAGAAGACGATGAGCGTCTTGCCGATTTAACCTGTGAATA
CCTGCAAAGCAATGGCCTTGGTGTGACGGTAGTCAGCGACGGTGAAGAAGCTATTCGCCGTATTCGTGCGGATCAGCCGG
ATCTGGTGGTGCTAGATTTGATGCTGCCCGGTGCCGACGGCCTGACGGTATGTCGTGAAGTGCGCAGTGCCTATAAGAAT
CCCATTCTCATGCTTACCGCTCGCACCGATGATATGGATCAGGTGCTGGGCTTGGAAATGGGCGCCGATGATTACGTGGC
CAAGCCGGTTAAACCCCGGGTGTTGTTGGCGCGGATCCGTGCCTTGTTACGTCGAGTGGAAACGGATAGTGAGCGTGATA
ATTCACCGGCACGCTTGGAATTCGGTGCCTTAGTGATCGATAACTCTGCCCGCGAAGTGACTTTGGCCGGCGATTCGGTG
GATCTTACCAGTGCGGAATACGATTTGCTTTGGCTGCTAGCGTCCAACGCGGGCACGGTGCTGTCACGGGAAACAATTTT
CGAGAAACTGCGGGGCATTCAATATGACGGGCAAGACCGCTCTATTGATGTGCGTATTTCCAGGATTCGCCCTAAAGTAG
GGGACGATCCAGAAAACCCCAAGCGCATCAAAACGGTACGCTCCAAGGGGTATCTGTTCGTCAAGGAAATCGGCGCAATA
TAA

Upstream 100 bases:

>100_bases
GTATAAACATACGATAGAGATACGTTTGTTACAGTTTGCCGGGTTGGCGTTGGAACAAAACGACAATAACGATACAAATT
TCAAGAAGGATAAGGACGGG

Downstream 100 bases:

>100_bases
CGGCTGAGTTGGTCGTTGCGGCGCAGGGATGACGCTGGGTGATGTTTGAATAGTATTTTCCTGAGGCTCTACGGGGGCTT
GTTGCTGGCGCTGTGTTTGA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTTVQDNPPAIMIVEDDERLADLTCEYLQSNGLGVTVVSDGEEAIRRIRADQPDLVVLDLMLPGADGLTVCREVRSAYKN
PILMLTARTDDMDQVLGLEMGADDYVAKPVKPRVLLARIRALLRRVETDSERDNSPARLEFGALVIDNSAREVTLAGDSV
DLTSAEYDLLWLLASNAGTVLSRETIFEKLRGIQYDGQDRSIDVRISRIRPKVGDDPENPKRIKTVRSKGYLFVKEIGAI

Sequences:

>Translated_240_residues
MTTVQDNPPAIMIVEDDERLADLTCEYLQSNGLGVTVVSDGEEAIRRIRADQPDLVVLDLMLPGADGLTVCREVRSAYKN
PILMLTARTDDMDQVLGLEMGADDYVAKPVKPRVLLARIRALLRRVETDSERDNSPARLEFGALVIDNSAREVTLAGDSV
DLTSAEYDLLWLLASNAGTVLSRETIFEKLRGIQYDGQDRSIDVRISRIRPKVGDDPENPKRIKTVRSKGYLFVKEIGAI
>Mature_239_residues
TTVQDNPPAIMIVEDDERLADLTCEYLQSNGLGVTVVSDGEEAIRRIRADQPDLVVLDLMLPGADGLTVCREVRSAYKNP
ILMLTARTDDMDQVLGLEMGADDYVAKPVKPRVLLARIRALLRRVETDSERDNSPARLEFGALVIDNSAREVTLAGDSVD
LTSAEYDLLWLLASNAGTVLSRETIFEKLRGIQYDGQDRSIDVRISRIRPKVGDDPENPKRIKTVRSKGYLFVKEIGAI

Specific function: Member of the two-component regulatory system rstB/rstA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=46.5217391304348, Blast_Score=193, Evalue=7e-51,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=42.7947598253275, Blast_Score=173, Evalue=9e-45,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=38.5964912280702, Blast_Score=163, Evalue=9e-42,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=40.5286343612335, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=38.3928571428571, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=31.858407079646, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=33.0472103004292, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=34.9775784753363, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=36.5638766519824, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=36.8888888888889, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=36.4864864864865, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787229, Length=236, Percent_Identity=33.0508474576271, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=29.4642857142857, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6322000, Length=101, Percent_Identity=35.6435643564356, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26643; Mature: 26512

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVQDNPPAIMIVEDDERLADLTCEYLQSNGLGVTVVSDGEEAIRRIRADQPDLVVLDL
CCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCEEEEEE
MLPGADGLTVCREVRSAYKNPILMLTARTDDMDQVLGLEMGADDYVAKPVKPRVLLARIR
EECCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCCCHHCCCCCHHHHHHHHH
ALLRRVETDSERDNSPARLEFGALVIDNSAREVTLAGDSVDLTSAEYDLLWLLASNAGTV
HHHHHHCCCCCCCCCCCEEEEEEEEEECCCCEEEEECCCEEECCCCEEEEEEEECCCCCE
LSRETIFEKLRGIQYDGQDRSIDVRISRIRPKVGDDPENPKRIKTVRSKGYLFVKEIGAI
EHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHCCCCEEEEECCCC
>Mature Secondary Structure 
TTVQDNPPAIMIVEDDERLADLTCEYLQSNGLGVTVVSDGEEAIRRIRADQPDLVVLDL
CCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCEEEEEE
MLPGADGLTVCREVRSAYKNPILMLTARTDDMDQVLGLEMGADDYVAKPVKPRVLLARIR
EECCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCCCHHCCCCCHHHHHHHHH
ALLRRVETDSERDNSPARLEFGALVIDNSAREVTLAGDSVDLTSAEYDLLWLLASNAGTV
HHHHHHCCCCCCCCCCCEEEEEEEEEECCCCEEEEECCCEEECCCCEEEEEEEECCCCCE
LSRETIFEKLRGIQYDGQDRSIDVRISRIRPKVGDDPENPKRIKTVRSKGYLFVKEIGAI
EHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1495392 [H]