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The map label for this gene is ybbO [C]

Identifier: 110636007

GI number: 110636007

Start: 3969824

End: 3970609

Strand: Reverse

Name: ybbO [C]

Synonym: Meso_3682

Alternate gene names: 110636007

Gene position: 3970609-3969824 (Counterclockwise)

Preceding gene: 110636008

Following gene: 110635995

Centisome position: 89.99

GC content: 61.2

Gene sequence:

>786_bases
ATGGCTGATAAGGCAGGGCTGGCCGTGATTACCGGCGCATCCACCGGTATTGGTTACGAACTGGCGAAATGTTGCGCGGC
GGCAGGTTACGACATGGTGGTGGCCGCCGACGAGCCAGAGATCGCCCGCGCAGCGGAGGAGTTCCGCGCTATGGGCGTCA
ATGCGGAGCCGGTGGAAGCGGATCTTGCCACGGCGGAAGGCGTGGAAAAGCTTTACGTGGCGCTCTCCGGACGCCCGGTG
GAATTGCTCTTCGCCAATGCCGGCAGGGGCTTGGGTCACGCTTTTCTCGACCAGGAGGTGGCCGAGATCAGGCACGTGAT
CGATACCAACATCACCGGAACCATTCTTCTGGTGCATCGAATAGGCCGTGATATGCGGCTCAGGAATCGCGGGCGCATCC
TCTTCACGGGTTCGATCGCCGGTTTCATGCCGGGCAGCTATCAGGCGGTCTACAACGCCACAAAGGCTTTCGTAGACAGT
TTTTCCTGGGCGCTTCGCAACGAGCTCAAGGATACGGACATCACCGTCACCTGCCTCATGCCCGGCCCGACCGATACCGA
GTTCTTCGAGCGGGCCGAAATGACGGACACAAAGGTCGGCTCGGAGAAAAAGATGAATCCCGCCAAGGTCGCGCGCATCG
GGTTTGAGGCCATGATGAAGGGCGAGGCCGGTGTCGTAGCCGGCTTCTCAAACAAGATTCAGGCGGCCATGGCACACCTG
ATGCCTGCCGGGCTACTCGCCGAGCAGCACCGGAAAATGGCGCAGCCGGGGACCGGGGAAACGTAA

Upstream 100 bases:

>100_bases
CGCCTGTCCTTGGAAGCAGGGCCGGAGGGCTACCGGAAATTCGCCTTTGAGCAGAATGAGACGACCAAGGTGGTTCTGAA
GCCGGGATGGGAGAACGCAA

Downstream 100 bases:

>100_bases
AGCCAGAGCGCTTCTCCCTGACGGCGGCCGTGGCCATCGCGGTCCTTCGGCGTGCATCCTGGCTCGACGCATTTGCGCGG
TCAGGGTTGAATCGCTTATC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MADKAGLAVITGASTGIGYELAKCCAAAGYDMVVAADEPEIARAAEEFRAMGVNAEPVEADLATAEGVEKLYVALSGRPV
ELLFANAGRGLGHAFLDQEVAEIRHVIDTNITGTILLVHRIGRDMRLRNRGRILFTGSIAGFMPGSYQAVYNATKAFVDS
FSWALRNELKDTDITVTCLMPGPTDTEFFERAEMTDTKVGSEKKMNPAKVARIGFEAMMKGEAGVVAGFSNKIQAAMAHL
MPAGLLAEQHRKMAQPGTGET

Sequences:

>Translated_261_residues
MADKAGLAVITGASTGIGYELAKCCAAAGYDMVVAADEPEIARAAEEFRAMGVNAEPVEADLATAEGVEKLYVALSGRPV
ELLFANAGRGLGHAFLDQEVAEIRHVIDTNITGTILLVHRIGRDMRLRNRGRILFTGSIAGFMPGSYQAVYNATKAFVDS
FSWALRNELKDTDITVTCLMPGPTDTEFFERAEMTDTKVGSEKKMNPAKVARIGFEAMMKGEAGVVAGFSNKIQAAMAHL
MPAGLLAEQHRKMAQPGTGET
>Mature_260_residues
ADKAGLAVITGASTGIGYELAKCCAAAGYDMVVAADEPEIARAAEEFRAMGVNAEPVEADLATAEGVEKLYVALSGRPVE
LLFANAGRGLGHAFLDQEVAEIRHVIDTNITGTILLVHRIGRDMRLRNRGRILFTGSIAGFMPGSYQAVYNATKAFVDSF
SWALRNELKDTDITVTCLMPGPTDTEFFERAEMTDTKVGSEKKMNPAKVARIGFEAMMKGEAGVVAGFSNKIQAAMAHLM
PAGLLAEQHRKMAQPGTGET

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4557649, Length=188, Percent_Identity=32.4468085106383, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4503817, Length=218, Percent_Identity=27.9816513761468, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI7657478, Length=195, Percent_Identity=29.7435897435897, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI7705855, Length=180, Percent_Identity=27.2222222222222, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI109715829, Length=193, Percent_Identity=27.979274611399, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1786701, Length=216, Percent_Identity=29.1666666666667, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787335, Length=196, Percent_Identity=29.0816326530612, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787820, Length=179, Percent_Identity=30.1675977653631, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082160, Length=187, Percent_Identity=27.2727272727273, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788459, Length=185, Percent_Identity=31.3513513513514, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI2367175, Length=194, Percent_Identity=30.4123711340206, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI87082100, Length=189, Percent_Identity=30.6878306878307, Blast_Score=61, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=198, Percent_Identity=27.7777777777778, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323882, Length=191, Percent_Identity=32.4607329842932, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319635, Length=227, Percent_Identity=26.431718061674, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007236, Length=200, Percent_Identity=30.5, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24640442, Length=189, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21358495, Length=252, Percent_Identity=27.3809523809524, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI116007238, Length=194, Percent_Identity=30.9278350515464, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24580925, Length=249, Percent_Identity=28.9156626506024, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27888; Mature: 27757

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKAGLAVITGASTGIGYELAKCCAAAGYDMVVAADEPEIARAAEEFRAMGVNAEPVEA
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCHH
DLATAEGVEKLYVALSGRPVELLFANAGRGLGHAFLDQEVAEIRHVIDTNITGTILLVHR
HHHHHHHHHHEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHEEEEEH
IGRDMRLRNRGRILFTGSIAGFMPGSYQAVYNATKAFVDSFSWALRNELKDTDITVTCLM
HCCCCEECCCCCEEEEECHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
PGPTDTEFFERAEMTDTKVGSEKKMNPAKVARIGFEAMMKGEAGVVAGFSNKIQAAMAHL
CCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHH
MPAGLLAEQHRKMAQPGTGET
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ADKAGLAVITGASTGIGYELAKCCAAAGYDMVVAADEPEIARAAEEFRAMGVNAEPVEA
CCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCHH
DLATAEGVEKLYVALSGRPVELLFANAGRGLGHAFLDQEVAEIRHVIDTNITGTILLVHR
HHHHHHHHHHEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHEEEEEH
IGRDMRLRNRGRILFTGSIAGFMPGSYQAVYNATKAFVDSFSWALRNELKDTDITVTCLM
HCCCCEECCCCCEEEEECHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
PGPTDTEFFERAEMTDTKVGSEKKMNPAKVARIGFEAMMKGEAGVVAGFSNKIQAAMAHL
CCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHH
MPAGLLAEQHRKMAQPGTGET
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]