Click here to switch to the map view.

The map label for this gene is mnmG

Identifier: 110635799

GI number: 110635799

Start: 3746477

End: 3748345

Strand: Reverse

Name: mnmG

Synonym: Meso_3471

Alternate gene names: 110635799

Gene position: 3748345-3746477 (Counterclockwise)

Preceding gene: 110635800

Following gene: 110635798

Centisome position: 84.95

GC content: 57.52

Gene sequence:

>1869_bases
ATGATTCATAAATTCGATGTCGTTGTGGTTGGTGGAGGCCACGCCGGTTGTGAGGCAGCGGCGGCGGCTGCTCGGGCCGG
CGCAAGGACAGCGCTTGTCACAATGCGGCGCGATACGATCGGCGTAATGTCCTGCAATCCCGCAATCGGCGGGATCGGCA
AGGGACAGCTGGTGCGCGAAGTCGATGCCTTGGATGGCCTCATGGGGCGGGTTGCCGATGCAGCTGGAATCCAGTTCCGT
CTCTTGAATCGGCGCAAGGGGCCAGCGGTGCGAGGGCCACGAACGCAGGCGGATCGCAAACTTTACCGCCAGGCTATGCA
GGCCGTCATTTCCGAACAAGAGAATCTTCAGGTTATCGAAGCTGAAGTGCATACGCTGGGAATGGAACATGGCCGAATCA
CGCATGTCGGCCTCTCCGGAGACTCGCAGATCAACTGCGCGGCTGTAGTCCTGACGACGGGAACCTTTTTGCGCGGATTG
ATCCATATTGGCCAGAAGAAAATTCCTGCTGGCCGGGTCAATGAACCGGCTGCGAAGGGTCTTTCGGCTTCCATGGAGGC
GGCTGGCTTTAAACTTGGACGACTGAAGACCGGGACGCCCCCTCGCCTCGATGGGCGGACGATCGAATGGAACATGCTCG
GATTTCAGAAAGCAGATGAGGATCCGGTTCCGTTTTCACTGCTGAGCGAAAAAATCCAAAACCCGCAAATCACATGTGGA
ATAACGCGAACGACAACGGACACGCACCGTATCATTCAAGAGAACCTCGACAAATCCGCAATGTATTCTGGCCAGATTGA
GGGAATTGGGCCGCGTTACTGTCCCTCGATCGAGGATAAGATCGTGAAGTTTGGGGAGAGGGACGGTCACCAGATTTTTC
TTGAGCCCGAGGGGCTCGATGACCACACCGTGTATCCAAATGGCCTCTCGACCTCGCTGCCTGAAGAGGTTCAGCACGCA
TTTCTTAAGACAATACCCGGACTCGCCAACGCGCACGTGCTGCAGCCGGGATATGCCATCGAGTATGATCACGTGGATCC
GCGCGAGCTTGAGCCGTCGCTTGAAACGCGTCGCGTCAGGGGTTTATTTCTTGCCGGGCAGATCAATGGCACGACCGGTT
ACGAGGAAGCTGCCGCTCAGGGCGTAATTGCCGGCATCAATGCAGCAAGCGTTGCATCGGGGAGCACGACTGTCGTTCCG
AGCCGAACCGATGCCTATATCGGTGTCATGATCGATGACCTGGTCACACGGGGAGTGACCGAACCCTACCGCATGTTCAC
ATCCCGTGCTGAGTTCCGACTGTCTCTCAGGGCCGACAATGCTGACGAGCGGCTCACGCCGCGGGCGATTGAGTGGGGTG
TGGCCTCGAAGGTGCGGCGCGATCGTTTCTATAAAGCAGAACAAGAACTTAGCGATGCGCGGGAACTTACGAAGGCACGC
GGACTAACGCCCAATGAGGCAGCCCGTCACGGAATTGCCGTCAATCAGGATGGGGTTCGGCGAAGTGCGTATGACCTGCT
TTCGTTCGCCGACATCAACATAGAAAGGCTGAAGGCGATCTGGCCGGAACTTGGTTCCATTGCCCCCAAAACTTGTGAAC
GCCTGGAGACAGAGGCTCGTTACGCGGTATACCTTGATCGCCAAGTCGCCGACGCGGAGCGAGTTCGCCGCGAAGAGGGC
AGGTCAATTCCCGACGGGATTGATTTCGATTCGGTTCCCGGCCTGTCGAACGAGTTGAAGTATAAGCTTCGTCAACGCAG
ACCGCGCACCTTAGCCGAGGCGCAGCGAATCGATGGAATGACCCCCGCCGCCCTGGCCCTCATTTTGGTTGCTATTCGAC
AAGGTGAGAAGATTCGGGGCGCTGCATGA

Upstream 100 bases:

>100_bases
AACAGCAATCCATGCGCCGCTGCCGTTTCACGTGAAACAGAGCCCGTCTTGACTAAACAGACCGATACGCTCATCTGGAG
CGAATGTTGGAAAGAGCCAG

Downstream 100 bases:

>100_bases
TGGCGGAGCGGTTCTCTGCCCTGCAGGCTGTCGCTGGCCCGGTTTCACGTGAAACATTTGACGGGTTAGTGGCTTTTGAA
GGCGAGTTTAGGAAGTGGTC

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MIHKFDVVVVGGGHAGCEAAAAAARAGARTALVTMRRDTIGVMSCNPAIGGIGKGQLVREVDALDGLMGRVADAAGIQFR
LLNRRKGPAVRGPRTQADRKLYRQAMQAVISEQENLQVIEAEVHTLGMEHGRITHVGLSGDSQINCAAVVLTTGTFLRGL
IHIGQKKIPAGRVNEPAAKGLSASMEAAGFKLGRLKTGTPPRLDGRTIEWNMLGFQKADEDPVPFSLLSEKIQNPQITCG
ITRTTTDTHRIIQENLDKSAMYSGQIEGIGPRYCPSIEDKIVKFGERDGHQIFLEPEGLDDHTVYPNGLSTSLPEEVQHA
FLKTIPGLANAHVLQPGYAIEYDHVDPRELEPSLETRRVRGLFLAGQINGTTGYEEAAAQGVIAGINAASVASGSTTVVP
SRTDAYIGVMIDDLVTRGVTEPYRMFTSRAEFRLSLRADNADERLTPRAIEWGVASKVRRDRFYKAEQELSDARELTKAR
GLTPNEAARHGIAVNQDGVRRSAYDLLSFADINIERLKAIWPELGSIAPKTCERLETEARYAVYLDRQVADAERVRREEG
RSIPDGIDFDSVPGLSNELKYKLRQRRPRTLAEAQRIDGMTPAALALILVAIRQGEKIRGAA

Sequences:

>Translated_622_residues
MIHKFDVVVVGGGHAGCEAAAAAARAGARTALVTMRRDTIGVMSCNPAIGGIGKGQLVREVDALDGLMGRVADAAGIQFR
LLNRRKGPAVRGPRTQADRKLYRQAMQAVISEQENLQVIEAEVHTLGMEHGRITHVGLSGDSQINCAAVVLTTGTFLRGL
IHIGQKKIPAGRVNEPAAKGLSASMEAAGFKLGRLKTGTPPRLDGRTIEWNMLGFQKADEDPVPFSLLSEKIQNPQITCG
ITRTTTDTHRIIQENLDKSAMYSGQIEGIGPRYCPSIEDKIVKFGERDGHQIFLEPEGLDDHTVYPNGLSTSLPEEVQHA
FLKTIPGLANAHVLQPGYAIEYDHVDPRELEPSLETRRVRGLFLAGQINGTTGYEEAAAQGVIAGINAASVASGSTTVVP
SRTDAYIGVMIDDLVTRGVTEPYRMFTSRAEFRLSLRADNADERLTPRAIEWGVASKVRRDRFYKAEQELSDARELTKAR
GLTPNEAARHGIAVNQDGVRRSAYDLLSFADINIERLKAIWPELGSIAPKTCERLETEARYAVYLDRQVADAERVRREEG
RSIPDGIDFDSVPGLSNELKYKLRQRRPRTLAEAQRIDGMTPAALALILVAIRQGEKIRGAA
>Mature_622_residues
MIHKFDVVVVGGGHAGCEAAAAAARAGARTALVTMRRDTIGVMSCNPAIGGIGKGQLVREVDALDGLMGRVADAAGIQFR
LLNRRKGPAVRGPRTQADRKLYRQAMQAVISEQENLQVIEAEVHTLGMEHGRITHVGLSGDSQINCAAVVLTTGTFLRGL
IHIGQKKIPAGRVNEPAAKGLSASMEAAGFKLGRLKTGTPPRLDGRTIEWNMLGFQKADEDPVPFSLLSEKIQNPQITCG
ITRTTTDTHRIIQENLDKSAMYSGQIEGIGPRYCPSIEDKIVKFGERDGHQIFLEPEGLDDHTVYPNGLSTSLPEEVQHA
FLKTIPGLANAHVLQPGYAIEYDHVDPRELEPSLETRRVRGLFLAGQINGTTGYEEAAAQGVIAGINAASVASGSTTVVP
SRTDAYIGVMIDDLVTRGVTEPYRMFTSRAEFRLSLRADNADERLTPRAIEWGVASKVRRDRFYKAEQELSDARELTKAR
GLTPNEAARHGIAVNQDGVRRSAYDLLSFADINIERLKAIWPELGSIAPKTCERLETEARYAVYLDRQVADAERVRREEG
RSIPDGIDFDSVPGLSNELKYKLRQRRPRTLAEAQRIDGMTPAALALILVAIRQGEKIRGAA

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=638, Percent_Identity=45.141065830721, Blast_Score=497, Evalue=1e-140,
Organism=Homo sapiens, GI19882217, Length=663, Percent_Identity=43.4389140271493, Blast_Score=483, Evalue=1e-136,
Organism=Homo sapiens, GI183227703, Length=678, Percent_Identity=42.4778761061947, Blast_Score=477, Evalue=1e-134,
Organism=Escherichia coli, GI2367273, Length=628, Percent_Identity=48.4076433121019, Blast_Score=573, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI17534255, Length=628, Percent_Identity=44.7452229299363, Blast_Score=515, Evalue=1e-146,
Organism=Saccharomyces cerevisiae, GI6321202, Length=621, Percent_Identity=46.2157809983897, Blast_Score=542, Evalue=1e-155,
Organism=Drosophila melanogaster, GI24658174, Length=630, Percent_Identity=48.2539682539683, Blast_Score=521, Evalue=1e-148,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_MESSB (Q11CN3)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_676007.1
- ProteinModelPortal:   Q11CN3
- SMR:   Q11CN3
- STRING:   Q11CN3
- GeneID:   4179879
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_3471
- NMPDR:   fig|266779.1.peg.1062
- eggNOG:   COG0445
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- PhylomeDB:   Q11CN3
- ProtClustDB:   PRK05192
- BioCyc:   MSP266779:MESO_3471-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 67858; Mature: 67858

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHKFDVVVVGGGHAGCEAAAAAARAGARTALVTMRRDTIGVMSCNPAIGGIGKGQLVRE
CCEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCCCCCCHHHHH
VDALDGLMGRVADAAGIQFRLLNRRKGPAVRGPRTQADRKLYRQAMQAVISEQENLQVIE
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
AEVHTLGMEHGRITHVGLSGDSQINCAAVVLTTGTFLRGLIHIGQKKIPAGRVNEPAAKG
HHHHHHCCCCCCEEEEECCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHC
LSASMEAAGFKLGRLKTGTPPRLDGRTIEWNMLGFQKADEDPVPFSLLSEKIQNPQITCG
CCHHHHHCCEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCCEEEE
ITRTTTDTHRIIQENLDKSAMYSGQIEGIGPRYCPSIEDKIVKFGERDGHQIFLEPEGLD
EEECCCHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCC
DHTVYPNGLSTSLPEEVQHAFLKTIPGLANAHVLQPGYAIEYDHVDPRELEPSLETRRVR
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCEEEECCCCHHHCCCCHHHHHEE
GLFLAGQINGTTGYEEAAAQGVIAGINAASVASGSTTVVPSRTDAYIGVMIDDLVTRGVT
EEEEEEEECCCCCHHHHHHCCEEECCCHHHCCCCCEEEECCCCCCEEHHHHHHHHHHCCC
EPYRMFTSRAEFRLSLRADNADERLTPRAIEWGVASKVRRDRFYKAEQELSDARELTKAR
HHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLTPNEAARHGIAVNQDGVRRSAYDLLSFADINIERLKAIWPELGSIAPKTCERLETEAR
CCCCCHHHHCCCEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHCCE
YAVYLDRQVADAERVRREEGRSIPDGIDFDSVPGLSNELKYKLRQRRPRTLAEAQRIDGM
EEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCC
TPAALALILVAIRQGEKIRGAA
CHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIHKFDVVVVGGGHAGCEAAAAAARAGARTALVTMRRDTIGVMSCNPAIGGIGKGQLVRE
CCEEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCCCCCCHHHHH
VDALDGLMGRVADAAGIQFRLLNRRKGPAVRGPRTQADRKLYRQAMQAVISEQENLQVIE
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
AEVHTLGMEHGRITHVGLSGDSQINCAAVVLTTGTFLRGLIHIGQKKIPAGRVNEPAAKG
HHHHHHCCCCCCEEEEECCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHC
LSASMEAAGFKLGRLKTGTPPRLDGRTIEWNMLGFQKADEDPVPFSLLSEKIQNPQITCG
CCHHHHHCCEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCCEEEE
ITRTTTDTHRIIQENLDKSAMYSGQIEGIGPRYCPSIEDKIVKFGERDGHQIFLEPEGLD
EEECCCHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCC
DHTVYPNGLSTSLPEEVQHAFLKTIPGLANAHVLQPGYAIEYDHVDPRELEPSLETRRVR
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCEEEECCCCHHHCCCCHHHHHEE
GLFLAGQINGTTGYEEAAAQGVIAGINAASVASGSTTVVPSRTDAYIGVMIDDLVTRGVT
EEEEEEEECCCCCHHHHHHCCEEECCCHHHCCCCCEEEECCCCCCEEHHHHHHHHHHCCC
EPYRMFTSRAEFRLSLRADNADERLTPRAIEWGVASKVRRDRFYKAEQELSDARELTKAR
HHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLTPNEAARHGIAVNQDGVRRSAYDLLSFADINIERLKAIWPELGSIAPKTCERLETEAR
CCCCCHHHHCCCEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHCCE
YAVYLDRQVADAERVRREEGRSIPDGIDFDSVPGLSNELKYKLRQRRPRTLAEAQRIDGM
EEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCC
TPAALALILVAIRQGEKIRGAA
CHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA