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The map label for this gene is cynT [H]

Identifier: 110635552

GI number: 110635552

Start: 3492876

End: 3493520

Strand: Reverse

Name: cynT [H]

Synonym: Meso_3223

Alternate gene names: 110635552

Gene position: 3493520-3492876 (Counterclockwise)

Preceding gene: 110635553

Following gene: 110635541

Centisome position: 79.17

GC content: 61.71

Gene sequence:

>645_bases
ATGGTGCATCTTCCTGAACGGCTTTTGGCCGGATATCGTAACTTCATGGCCGGGCGCTATAGCGCCGAGAGTGCTCGCTA
TCGATCCTTGGCCCGTGAGGGGCAGTCGCCGGAGACTATGGTGATCGCCTGCTGCGATTCCCGCGCCGCTCCCGAGACCA
TCTTCGATTCCGGCCCCGGCGAGCTCTTCGTCGTCCGCAACGTTGCCAATCTCGTGCCGCCCTATGCGCCGGATGAGTAC
CACCACGGCACCTCCGCGGCACTCGAATTTGCCGTGCAGAGCCTCAAGGTGAAAAACATCGTGGTCATGGGCCACGGGCG
CTGCGGCGGTATCGGGGCTGCGCTGAACCCTTCCGCCGAGCCGCTTTCCCCCGGCGATTTTATTGGCAGATGGATGAGCC
TTGTTGCTCCCGCGGCTGAGGCCGTCGCGGGTAACAAACTGCTCACGCCCGCCGAGCGGCAGACTGCGCTTGAGCGCATT
TCTATCCGGTTTCAGGTCGAGAATCTGCGTAGCTTTCCCTGTGTGCGGATTCTGGAGCAGAAAGGGAAGCTGACTCTCCA
TGGCGCCTGGTTCGATATATCGAGCGGCGAACTCTGGGTGATGGATCCGAATACCGGGGACTTCGCCCGCCCTGATCTAG
GCTGA

Upstream 100 bases:

>100_bases
TGGAACTTCGCAAGCTGGCGCTGCCAGGGAATAATTTTCCGGAGCGAGGCCTTTAACCTGACGCTTGCCCAGCCGTTTAA
TCCCGGTTATTCGCAATGGC

Downstream 100 bases:

>100_bases
GATCTCGCTGGTCTCGATTATCACCGATGCCATTGCCGGCTCCGGCAGCCGCCGCCAAAAGAGCCATGCCAGGATGGCAA
TGGCGCCCATCGACGGGATC

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MVHLPERLLAGYRNFMAGRYSAESARYRSLAREGQSPETMVIACCDSRAAPETIFDSGPGELFVVRNVANLVPPYAPDEY
HHGTSAALEFAVQSLKVKNIVVMGHGRCGGIGAALNPSAEPLSPGDFIGRWMSLVAPAAEAVAGNKLLTPAERQTALERI
SIRFQVENLRSFPCVRILEQKGKLTLHGAWFDISSGELWVMDPNTGDFARPDLG

Sequences:

>Translated_214_residues
MVHLPERLLAGYRNFMAGRYSAESARYRSLAREGQSPETMVIACCDSRAAPETIFDSGPGELFVVRNVANLVPPYAPDEY
HHGTSAALEFAVQSLKVKNIVVMGHGRCGGIGAALNPSAEPLSPGDFIGRWMSLVAPAAEAVAGNKLLTPAERQTALERI
SIRFQVENLRSFPCVRILEQKGKLTLHGAWFDISSGELWVMDPNTGDFARPDLG
>Mature_214_residues
MVHLPERLLAGYRNFMAGRYSAESARYRSLAREGQSPETMVIACCDSRAAPETIFDSGPGELFVVRNVANLVPPYAPDEY
HHGTSAALEFAVQSLKVKNIVVMGHGRCGGIGAALNPSAEPLSPGDFIGRWMSLVAPAAEAVAGNKLLTPAERQTALERI
SIRFQVENLRSFPCVRILEQKGKLTLHGAWFDISSGELWVMDPNTGDFARPDLG

Specific function: Reversible Hydration Of Carbon Dioxide. Carbon Dioxide Formed In The Bicarbonate-Dependent Decomposition Of Cyanate By Cyanase (Cyns) Diffuses Out Of The Cell Faster Than It Would Be Hydrated To Bicarbonate, So The Apparent Function Of This Enzyme Is To C

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=203, Percent_Identity=32.0197044334975, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786318, Length=173, Percent_Identity=31.2138728323699, Blast_Score=68, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115532990, Length=240, Percent_Identity=27.5, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25147564, Length=214, Percent_Identity=27.5700934579439, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324292, Length=177, Percent_Identity=29.3785310734463, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23254; Mature: 23254

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHLPERLLAGYRNFMAGRYSAESARYRSLAREGQSPETMVIACCDSRAAPETIFDSGPG
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHCCCCC
ELFVVRNVANLVPPYAPDEYHHGTSAALEFAVQSLKVKNIVVMGHGRCGGIGAALNPSAE
CEEEEECHHHHCCCCCCCCCCCCHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCC
PLSPGDFIGRWMSLVAPAAEAVAGNKLLTPAERQTALERISIRFQVENLRSFPCVRILEQ
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEEEEECCCCCCHHHHHHHH
KGKLTLHGAWFDISSGELWVMDPNTGDFARPDLG
CCCEEEEEEEEEECCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MVHLPERLLAGYRNFMAGRYSAESARYRSLAREGQSPETMVIACCDSRAAPETIFDSGPG
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHCCCCC
ELFVVRNVANLVPPYAPDEYHHGTSAALEFAVQSLKVKNIVVMGHGRCGGIGAALNPSAE
CEEEEECHHHHCCCCCCCCCCCCHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCCCCCC
PLSPGDFIGRWMSLVAPAAEAVAGNKLLTPAERQTALERISIRFQVENLRSFPCVRILEQ
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEEEEEECCCCCCHHHHHHHH
KGKLTLHGAWFDISSGELWVMDPNTGDFARPDLG
CCCEEEEEEEEEECCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]