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The map label for this gene is tal

Identifier: 110635541

GI number: 110635541

Start: 3481535

End: 3482188

Strand: Reverse

Name: tal

Synonym: Meso_3212

Alternate gene names: 110635541

Gene position: 3482188-3481535 (Counterclockwise)

Preceding gene: 110635552

Following gene: 110635537

Centisome position: 78.92

GC content: 58.1

Gene sequence:

>654_bases
ATGAAGTTTTTCGTCGACACCGCCGATGTGAACGAAATCCGCGAACTGAGCGAAACAGGGCTTCTGGACGGGGTGACGAC
GAACCCCTCGCTCATCATGAAGTCGGGCCGGCCTATTCTCGAGGTCACGAGGGAAATCTGCGAGATCGTCGACGGACCGG
TGTCGGCGGAGGTCACCGCGGTCGATTTCAAGGAAATGATGCGCGAAGCAGACATTCTTTCAAAGATTGCCGATAACATT
GCCATCAAAGTGCCGCTGACGATGGACGGGCTCAAGGCCTGCAAGGCGCTCACCTCCAGCGGCCGGATGGTGAATGTCAC
CCTCTGCTTCTCCGCCAATCAGGCGCTGCTTGCGGCCAAGGCCGGCGCTACGTTCATCTCGCCCTTTATCGGCCGGATCG
ACGACATGGGCATCGACGGCATGGAACTGATCGCGGAGATCCGCACAATTTACGACAATTACGATTTCGATACGGAAATT
CTCGCCGCATCGATTCGCTCGGTCAATCATGTCAAGCAGGCGGCTATCATCGGCGCCGATGTCGCTACCGTTCCGCCAGC
GGTGCTGAAATCGCTCGTGAAGCACCCGCTCACCGACAAGGGACTCGAAGCGTTCCTGGCGGATTGGGCCAAGACCGGCC
AGAAAATCGGCTGA

Upstream 100 bases:

>100_bases
CTCTCATTGAGCGTGACCTTGCCCTTTTCTTGGATTAGAGCAAGGCCGAGCTTAAATTGGAGCGGAAAATGGCCGACAGG
CGCCCGCGAAGGAGAGAACC

Downstream 100 bases:

>100_bases
AGATGAGGCGATTCACCCTCCCCACAAGTGAGGGTGAACTAGAGCCGTTCATCTGTAAATGATTCCATTTGAAGATGAAC
GGCTCTAGCCACCAAATTCC

Product: putative translaldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKFFVDTADVNEIRELSETGLLDGVTTNPSLIMKSGRPILEVTREICEIVDGPVSAEVTAVDFKEMMREADILSKIADNI
AIKVPLTMDGLKACKALTSSGRMVNVTLCFSANQALLAAKAGATFISPFIGRIDDMGIDGMELIAEIRTIYDNYDFDTEI
LAASIRSVNHVKQAAIIGADVATVPPAVLKSLVKHPLTDKGLEAFLADWAKTGQKIG

Sequences:

>Translated_217_residues
MKFFVDTADVNEIRELSETGLLDGVTTNPSLIMKSGRPILEVTREICEIVDGPVSAEVTAVDFKEMMREADILSKIADNI
AIKVPLTMDGLKACKALTSSGRMVNVTLCFSANQALLAAKAGATFISPFIGRIDDMGIDGMELIAEIRTIYDNYDFDTEI
LAASIRSVNHVKQAAIIGADVATVPPAVLKSLVKHPLTDKGLEAFLADWAKTGQKIG
>Mature_217_residues
MKFFVDTADVNEIRELSETGLLDGVTTNPSLIMKSGRPILEVTREICEIVDGPVSAEVTAVDFKEMMREADILSKIADNI
AIKVPLTMDGLKACKALTSSGRMVNVTLCFSANQALLAAKAGATFISPFIGRIDDMGIDGMELIAEIRTIYDNYDFDTEI
LAASIRSVNHVKQAAIIGADVATVPPAVLKSLVKHPLTDKGLEAFLADWAKTGQKIG

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 3B subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=177, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI87081788, Length=211, Percent_Identity=31.2796208530806, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790382, Length=211, Percent_Identity=32.2274881516588, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786189, Length=173, Percent_Identity=32.9479768786127, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1788807, Length=196, Percent_Identity=30.1020408163265, Blast_Score=72, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25153750, Length=245, Percent_Identity=30.2040816326531, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25153752, Length=100, Percent_Identity=35, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6321480, Length=208, Percent_Identity=30.2884615384615, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323386, Length=199, Percent_Identity=33.1658291457286, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45549185, Length=174, Percent_Identity=34.4827586206897, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAL_MESSB (Q11DE1)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_675749.1
- ProteinModelPortal:   Q11DE1
- SMR:   Q11DE1
- STRING:   Q11DE1
- GeneID:   4182756
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_3212
- NMPDR:   fig|266779.1.peg.73
- eggNOG:   COG0176
- HOGENOM:   HBG533000
- OMA:   IHKNIVI
- PhylomeDB:   Q11DE1
- ProtClustDB:   PRK01362
- BioCyc:   MSP266779:MESO_3212-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00494
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004731
- InterPro:   IPR022999
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- TIGRFAMs:   TIGR00875

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 23329; Mature: 23329

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFVDTADVNEIRELSETGLLDGVTTNPSLIMKSGRPILEVTREICEIVDGPVSAEVTA
CCEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEHH
VDFKEMMREADILSKIADNIAIKVPLTMDGLKACKALTSSGRMVNVTLCFSANQALLAAK
HHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHH
AGATFISPFIGRIDDMGIDGMELIAEIRTIYDNYDFDTEILAASIRSVNHVKQAAIIGAD
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
VATVPPAVLKSLVKHPLTDKGLEAFLADWAKTGQKIG
HHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKFFVDTADVNEIRELSETGLLDGVTTNPSLIMKSGRPILEVTREICEIVDGPVSAEVTA
CCEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEHH
VDFKEMMREADILSKIADNIAIKVPLTMDGLKACKALTSSGRMVNVTLCFSANQALLAAK
HHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHH
AGATFISPFIGRIDDMGIDGMELIAEIRTIYDNYDFDTEILAASIRSVNHVKQAAIIGAD
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
VATVPPAVLKSLVKHPLTDKGLEAFLADWAKTGQKIG
HHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA