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The map label for this gene is yafC [C]

Identifier: 110635169

GI number: 110635169

Start: 3084188

End: 3085108

Strand: Reverse

Name: yafC [C]

Synonym: Meso_2836

Alternate gene names: 110635169

Gene position: 3085108-3084188 (Counterclockwise)

Preceding gene: 110635173

Following gene: 110635164

Centisome position: 69.92

GC content: 62.11

Gene sequence:

>921_bases
ATGGCTTATCTGGACAATCTTGCTGTTTTCGTGCGTGTGGTGGAACTGGGGGGCCTTTCGGCGGCAGGGCGCGACCTGCG
CATCTCGCCTGCGGTTGCATCCAACCGCATCAAGGAATTGGAAAAGCATCTCGGCGTGCGGTTGCTCAACCGCACGACAC
GGCAGCTCACCGCGACGGAACATGGCCGTGTCTTCTATGACGGCGCCAAGAGGGTGCTTGAAGCCTTGGACGAGGCTGAA
GGGGCCGTGGCCGCGCTTTCCGGCCAGCCGCGCGGCACGATCCGTGTGACGGCGCCGCTCGGTCTCGGTAAACGCCTGAT
CGCCAGCGGCATTCCGGAATTCCGTGAGCGCTATCCGCAGATTGAGGTGAGGCTCAGGCTTTCGGACCGTGACGTGGACA
TCATGCGTGAGGGGATCGATGTCGCTTTCAAGCTGGGGCTCCTGGAAAATTCAAGCCTCCGCATGCGCGGCATCATGGAT
TGCGAGCGGGTGCTGGCGGCTTCGCCCGTTTATCTTGAACGGCGCGGGGAGCCCGAGCGGCCGGAGCAACTGGTGGAGGA
ACAGCACGATTGCCTGATGCTTCGCTTCCCCGGCGTGCGTGAGTATTTCTGGACGCTGGCGACGCCGGAGGGGCCGAAGA
AATTCGAGGTGCGCGGGCCTTTCGACACGGATGATGGCGATGTGATCACCGGCTGGGCGCTCGCCGGCCACGGGATCATC
AATAAGCCACGCTTCGAGATCGAGCCTTTCATCCGTGACGGACGGCTCAAGATCATTCTGGCCAAAACACCGCCGACAAC
GGTTACGCTGGCGGCGGTCTATCCGCACAAGAAGCTGCAGGATCCCAAGGTGCGTCTGCTGGTGGATTTCATGGCCGAGC
GTTGCCAGCGCATGATCGAGGAGATTTTGAGGGGGCGGTGA

Upstream 100 bases:

>100_bases
GGCAAGCTTACGGCTTCTGCTCTAAAGGAAAAGAGATGGAGAGCACGATGACTTTCAAATTTTTCTGGAAAATCGCAGAG
CTGTCGGTTTGATAGGCGTC

Downstream 100 bases:

>100_bases
TCAGCTCAGCGCCCGCATCACCTCTGCTGCCGTCATGGCGGCGATGACAGCGGGTCGCTTGTCGCGAACCGTTTCGCCTC
CGATAGGTGTGATGAGCCGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MAYLDNLAVFVRVVELGGLSAAGRDLRISPAVASNRIKELEKHLGVRLLNRTTRQLTATEHGRVFYDGAKRVLEALDEAE
GAVAALSGQPRGTIRVTAPLGLGKRLIASGIPEFRERYPQIEVRLRLSDRDVDIMREGIDVAFKLGLLENSSLRMRGIMD
CERVLAASPVYLERRGEPERPEQLVEEQHDCLMLRFPGVREYFWTLATPEGPKKFEVRGPFDTDDGDVITGWALAGHGII
NKPRFEIEPFIRDGRLKIILAKTPPTTVTLAAVYPHKKLQDPKVRLLVDFMAERCQRMIEEILRGR

Sequences:

>Translated_306_residues
MAYLDNLAVFVRVVELGGLSAAGRDLRISPAVASNRIKELEKHLGVRLLNRTTRQLTATEHGRVFYDGAKRVLEALDEAE
GAVAALSGQPRGTIRVTAPLGLGKRLIASGIPEFRERYPQIEVRLRLSDRDVDIMREGIDVAFKLGLLENSSLRMRGIMD
CERVLAASPVYLERRGEPERPEQLVEEQHDCLMLRFPGVREYFWTLATPEGPKKFEVRGPFDTDDGDVITGWALAGHGII
NKPRFEIEPFIRDGRLKIILAKTPPTTVTLAAVYPHKKLQDPKVRLLVDFMAERCQRMIEEILRGR
>Mature_305_residues
AYLDNLAVFVRVVELGGLSAAGRDLRISPAVASNRIKELEKHLGVRLLNRTTRQLTATEHGRVFYDGAKRVLEALDEAEG
AVAALSGQPRGTIRVTAPLGLGKRLIASGIPEFRERYPQIEVRLRLSDRDVDIMREGIDVAFKLGLLENSSLRMRGIMDC
ERVLAASPVYLERRGEPERPEQLVEEQHDCLMLRFPGVREYFWTLATPEGPKKFEVRGPFDTDDGDVITGWALAGHGIIN
KPRFEIEPFIRDGRLKIILAKTPPTTVTLAAVYPHKKLQDPKVRLLVDFMAERCQRMIEEILRGR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=32.7702702702703, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=29.4520547945205, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=31.4878892733564, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=29.9319727891156, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=30.1694915254237, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1787128, Length=301, Percent_Identity=28.2392026578073, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787589, Length=285, Percent_Identity=26.6666666666667, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788481, Length=291, Percent_Identity=27.8350515463918, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788706, Length=174, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788748, Length=176, Percent_Identity=33.5227272727273, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789173, Length=256, Percent_Identity=25.78125, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI145693105, Length=189, Percent_Identity=26.984126984127, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787601, Length=122, Percent_Identity=30.327868852459, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790011, Length=283, Percent_Identity=21.9081272084806, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI157672245, Length=144, Percent_Identity=27.7777777777778, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34487; Mature: 34355

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS50931 HTH_LYSR ; PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYLDNLAVFVRVVELGGLSAAGRDLRISPAVASNRIKELEKHLGVRLLNRTTRQLTATE
CCCHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHECCC
HGRVFYDGAKRVLEALDEAEGAVAALSGQPRGTIRVTAPLGLGKRLIASGIPEFRERYPQ
CCEEEEHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCHHHHHCCCHHHHHHCCC
IEVRLRLSDRDVDIMREGIDVAFKLGLLENSSLRMRGIMDCERVLAASPVYLERRGEPER
EEEEEEECCCCHHHHHHCCCEEEEEEEECCCCEEEHHHHHHHHHHHCCCEEEECCCCCCC
PEQLVEEQHDCLMLRFPGVREYFWTLATPEGPKKFEVRGPFDTDDGDVITGWALAGHGII
HHHHHHHHCCEEEEECCCHHHHHEEECCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCC
NKPRFEIEPFIRDGRLKIILAKTPPTTVTLAAVYPHKKLQDPKVRLLVDFMAERCQRMIE
CCCCCEECCEEECCEEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
EILRGR
HHHCCC
>Mature Secondary Structure 
AYLDNLAVFVRVVELGGLSAAGRDLRISPAVASNRIKELEKHLGVRLLNRTTRQLTATE
CCHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHECCC
HGRVFYDGAKRVLEALDEAEGAVAALSGQPRGTIRVTAPLGLGKRLIASGIPEFRERYPQ
CCEEEEHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCCCCHHHHHCCCHHHHHHCCC
IEVRLRLSDRDVDIMREGIDVAFKLGLLENSSLRMRGIMDCERVLAASPVYLERRGEPER
EEEEEEECCCCHHHHHHCCCEEEEEEEECCCCEEEHHHHHHHHHHHCCCEEEECCCCCCC
PEQLVEEQHDCLMLRFPGVREYFWTLATPEGPKKFEVRGPFDTDDGDVITGWALAGHGII
HHHHHHHHCCEEEEECCCHHHHHEEECCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCC
NKPRFEIEPFIRDGRLKIILAKTPPTTVTLAAVYPHKKLQDPKVRLLVDFMAERCQRMIE
CCCCCEECCEEECCEEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
EILRGR
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]