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The map label for this gene is soxB [H]

Identifier: 110634978

GI number: 110634978

Start: 2856381

End: 2857571

Strand: Reverse

Name: soxB [H]

Synonym: Meso_2644

Alternate gene names: 110634978

Gene position: 2857571-2856381 (Counterclockwise)

Preceding gene: 110634979

Following gene: 110634977

Centisome position: 64.76

GC content: 61.71

Gene sequence:

>1191_bases
ATGAAAACGAGACATAAGGCCGACGTAGCTATTATCGGCGGAGGTATCATCGGCCTGGCCATCGCTTACGAGCTCAAGAT
GAGAGGCTGTTCGCCGGTCGTTCTTGAACGGGGCATCATAGGAGCGGAGGCTTCCAGCCGGAACGGCGGTGGCGTTCGGG
CGCAAGGCCGCCTTCTGCCGGAGATCCCCGTGGCCATGAAGGCGATCGAAATGTGGCAGGATCTGCATGTGCGTCTCGGC
CATCCTACCGGTTATGGGCAGACAGGACATGTCTACATCGCGGAAAGCCAGGCAGATCTCGACATGCTGAACCGCAAGCG
CGATCGCGAAATGGCGGTCGGCTTGAAGTCCGAGATGATCGGCCCGGACCGGCTGCTGGAGCTTGCTCCCGGCCTGGAAC
ATGGGTATTTCGGCGCGAAATTCTGCCCCACCGATGGTGCTGCCGACCCCTCCCAGGCGACGCTTGCATTTGCCCGCGCC
TATGAAAAGCTGGGGGGCATTATCCTCGACAATGAGCGGGTTCTTGCCATCGGCACCCGGAACCGCCGAGTGACCCATGT
GGAAACGGAGGCGAGCATCGTGGAGGCGCCGGCCGTCGTGCTAGCCGCCGGAACCTGGTCCCCGGTGATCGCCCAGACCA
TCGATCTCTATCTCCCAGTCTATCCCCGCCGCAACAACATGTCGTTCACGGTACCGTTGCCGCTGCAGACGACGGTCTTT
ACCCAAAGCGCTTCGCTCAACATGGCGATCCGCCAGATGCCGGATGGAACCGTCATGCTCGCATCCGGCGCCGGTCAGCC
GGAGGGCAAGACCGCCTTTACCTATCGCAAGGATTATCACGGGCTTGCGCCCGGCGAGACGCCTCGGCCGGCCAAGGCGG
ACGAGATGTTTCCGGCCGTCCGGGCCGCCCCGATTGCGGGGCGCTGGGCGGGAATTACGGAAAACACGCCTGACAAGATG
CCGATCGTCGACCTGATAGATGAGAAGCAGGGTGGAGCGGACGGCTTCTATGTGGCGACCGGCTTCAGCGGACACGGTTT
TTGCCTTGGTCCGCTGATCGGCAGGGAGATGGCCGAATGGATTGTGAACGGCCATACGACGATCGACCTTTCGCCCTTTG
CCTTCGAGCGCTTCACCAAAGGCAACAGCCCCTGGGACCTCATTAATCACCAGCTGCAGGAAGTGGGATGA

Upstream 100 bases:

>100_bases
TTCAGCCAGGGCTGTGCCGCCCAAAGCTGCCGCGTTTGGGTGGAGCGCTGGAAGGCGCCTGAACATTCAGGGCTCGAAAC
GGGCCAAAGGGGGTCGAAGC

Downstream 100 bases:

>100_bases
TGGATATGCCGGATAGCAAAATCGGGATAGTCGAAAAGATCGCCCTCCTCAGTGAGGCAGATTTCAACGCCATCCTAAGG
CAAGCCGGTAAACCCGTTGC

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKTRHKADVAIIGGGIIGLAIAYELKMRGCSPVVLERGIIGAEASSRNGGGVRAQGRLLPEIPVAMKAIEMWQDLHVRLG
HPTGYGQTGHVYIAESQADLDMLNRKRDREMAVGLKSEMIGPDRLLELAPGLEHGYFGAKFCPTDGAADPSQATLAFARA
YEKLGGIILDNERVLAIGTRNRRVTHVETEASIVEAPAVVLAAGTWSPVIAQTIDLYLPVYPRRNNMSFTVPLPLQTTVF
TQSASLNMAIRQMPDGTVMLASGAGQPEGKTAFTYRKDYHGLAPGETPRPAKADEMFPAVRAAPIAGRWAGITENTPDKM
PIVDLIDEKQGGADGFYVATGFSGHGFCLGPLIGREMAEWIVNGHTTIDLSPFAFERFTKGNSPWDLINHQLQEVG

Sequences:

>Translated_396_residues
MKTRHKADVAIIGGGIIGLAIAYELKMRGCSPVVLERGIIGAEASSRNGGGVRAQGRLLPEIPVAMKAIEMWQDLHVRLG
HPTGYGQTGHVYIAESQADLDMLNRKRDREMAVGLKSEMIGPDRLLELAPGLEHGYFGAKFCPTDGAADPSQATLAFARA
YEKLGGIILDNERVLAIGTRNRRVTHVETEASIVEAPAVVLAAGTWSPVIAQTIDLYLPVYPRRNNMSFTVPLPLQTTVF
TQSASLNMAIRQMPDGTVMLASGAGQPEGKTAFTYRKDYHGLAPGETPRPAKADEMFPAVRAAPIAGRWAGITENTPDKM
PIVDLIDEKQGGADGFYVATGFSGHGFCLGPLIGREMAEWIVNGHTTIDLSPFAFERFTKGNSPWDLINHQLQEVG
>Mature_396_residues
MKTRHKADVAIIGGGIIGLAIAYELKMRGCSPVVLERGIIGAEASSRNGGGVRAQGRLLPEIPVAMKAIEMWQDLHVRLG
HPTGYGQTGHVYIAESQADLDMLNRKRDREMAVGLKSEMIGPDRLLELAPGLEHGYFGAKFCPTDGAADPSQATLAFARA
YEKLGGIILDNERVLAIGTRNRRVTHVETEASIVEAPAVVLAAGTWSPVIAQTIDLYLPVYPRRNNMSFTVPLPLQTTVF
TQSASLNMAIRQMPDGTVMLASGAGQPEGKTAFTYRKDYHGLAPGETPRPAKADEMFPAVRAAPIAGRWAGITENTPDKM
PIVDLIDEKQGGADGFYVATGFSGHGFCLGPLIGREMAEWIVNGHTTIDLSPFAFERFTKGNSPWDLINHQLQEVG

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI194306651, Length=404, Percent_Identity=27.2277227722772, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI24797151, Length=396, Percent_Identity=23.7373737373737, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI197927446, Length=394, Percent_Identity=24.6192893401015, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI21361378, Length=394, Percent_Identity=24.6192893401015, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994045, Length=398, Percent_Identity=23.3668341708543, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20130091, Length=388, Percent_Identity=25.2577319587629, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI28571104, Length=393, Percent_Identity=25.1908396946565, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 42756; Mature: 42756

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRHKADVAIIGGGIIGLAIAYELKMRGCSPVVLERGIIGAEASSRNGGGVRAQGRLLP
CCCCCCCCEEEECCCCEEEHEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCEEECCCCCC
EIPVAMKAIEMWQDLHVRLGHPTGYGQTGHVYIAESQADLDMLNRKRDREMAVGLKSEMI
CCHHHHHHHHHHHHCEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHCC
GPDRLLELAPGLEHGYFGAKFCPTDGAADPSQATLAFARAYEKLGGIILDNERVLAIGTR
CHHHHHHHCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHCCEEECCCEEEEEECC
NRRVTHVETEASIVEAPAVVLAAGTWSPVIAQTIDLYLPVYPRRNNMSFTVPLPLQTTVF
CCEEEEEECCHHHHCCCEEEEEECCCCHHHHHHHHHEEECCCCCCCCEEEEECCCEEEEE
TQSASLNMAIRQMPDGTVMLASGAGQPEGKTAFTYRKDYHGLAPGETPRPAKADEMFPAV
ECCCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
RAAPIAGRWAGITENTPDKMPIVDLIDEKQGGADGFYVATGFSGHGFCLGPLIGREMAEW
HCCCCCCCCCCCCCCCCCCCCHHHEECCCCCCCCCEEEEECCCCCCEEEHHHHHHHHHHH
IVNGHTTIDLSPFAFERFTKGNSPWDLINHQLQEVG
HHCCCCEEEECHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKTRHKADVAIIGGGIIGLAIAYELKMRGCSPVVLERGIIGAEASSRNGGGVRAQGRLLP
CCCCCCCCEEEECCCCEEEHEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCEEECCCCCC
EIPVAMKAIEMWQDLHVRLGHPTGYGQTGHVYIAESQADLDMLNRKRDREMAVGLKSEMI
CCHHHHHHHHHHHHCEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHCC
GPDRLLELAPGLEHGYFGAKFCPTDGAADPSQATLAFARAYEKLGGIILDNERVLAIGTR
CHHHHHHHCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHCCEEECCCEEEEEECC
NRRVTHVETEASIVEAPAVVLAAGTWSPVIAQTIDLYLPVYPRRNNMSFTVPLPLQTTVF
CCEEEEEECCHHHHCCCEEEEEECCCCHHHHHHHHHEEECCCCCCCCEEEEECCCEEEEE
TQSASLNMAIRQMPDGTVMLASGAGQPEGKTAFTYRKDYHGLAPGETPRPAKADEMFPAV
ECCCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
RAAPIAGRWAGITENTPDKMPIVDLIDEKQGGADGFYVATGFSGHGFCLGPLIGREMAEW
HCCCCCCCCCCCCCCCCCCCCHHHEECCCCCCCCCEEEEECCCCCCEEEHHHHHHHHHHH
IVNGHTTIDLSPFAFERFTKGNSPWDLINHQLQEVG
HHCCCCEEEECHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]