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The map label for this gene is torZ [C]

Identifier: 110634979

GI number: 110634979

Start: 2857555

End: 2859870

Strand: Reverse

Name: torZ [C]

Synonym: Meso_2645

Alternate gene names: 110634979

Gene position: 2859870-2857555 (Counterclockwise)

Preceding gene: 110634980

Following gene: 110634978

Centisome position: 64.81

GC content: 62.35

Gene sequence:

>2316_bases
ATGGGTCAGGCGCAGAAGATTCTGCACAGCAGTCACTGGGGGATATTCTTCGCGGTCGTCGAGAACGGCCGGATCGTGGA
TATCGAACCCTTCAAAGGCGATCCTGCGCCGTCTCCATTGCTGGCTTCGATCCCGGAGTGGACGAATGCCGAAACCCGGG
TTCTCCGGCCCATGGTTCGCGAGGGCTGGCTGCGCGCCCACGACGCCGGGCGGCCGCAGGACAACCGCGACCGGCGCGGC
AAGGACGAATTCATCGAGGTGTCATGGCCCCAAGCCATTGAATTGATCGCATCCGAGATCAACCGTGTGAGGACGGAACT
CGGAAATTCCTCGATTTTTGCCGGCTCTTACGGTTGGACGAGTGCCGGGCGGTTCCACCACGCGGCCTCCCAGATCAAGC
GGCTGCTGAATCTCGTCGGCGGTTATACCGGCCACGTGGACACCTACAGCATTGCTGCAGGGCCCGTCCTGCTGCGCTTC
GTACTCGGCAACGATTTTGCCTCGGGCGGACGCGGCACGACTCTCGATACCGTCGTGGAGAATACCCAAACCCTACTGGT
GTTCGGTGCGCTCTCTCCGCGCACTGCGCAGAACGAGGCGGGTGGCGTTGCCAAGCATAAGCTGGAAGGCTATCTGCGCC
AGATCGCGGATCGGGGAATACGGGTGATCCTGATTTCCCCTTGCCGCGACGACGTGCCGGAATTCCTGAACGCCGAGTGG
TGGCCGATCCGGCCTGGGACCGATGCGGCACTTCTGCTGGCGCTGACGCGGGAGTTGGTTCGCTCCGGCCGTGCCGATCT
CGACTTCCTCAACCGTTATTGCAGCGGCTCGGAGCGGTTCCTGTCCTATCTGGCCGGCGAAACCGACGGACAGGAGAAGA
CGGCCGAATGGGCCGAAGCGATCACCGGCATTCCCGGCGCGGCCATTCGCGGCTTGGCCCCTACGATTGCCGACACCCGG
ACGATGATTACCCTCAGCTGGGCCCTGCAGCGTGCCGACCATGGTGAGCAGCCTTATTGGGCGGCCATTGCTCTTGCCGC
GGCAGCGGGGCAGATCGGCCTGCCAGGCGGTGGTTTCGGTTTCGGTTTTGGATCGGTTTCCGGGAACGGTTCTCCCTATG
GGGTCATTCAGGCACCGGCGCTGCCTCAGTTGAAGAATCCGATCAGGAGCTTCATTCCTGTCGCGCGGATCGCCGACATG
CTTCTCAACCCGGGCCAGCCTTTCGATTACTCGGGCGCAAGCTACACCTATCCCGATGCACGCCTGATTTATTGGGCAGG
CGGAAATCCGTTCCACCACCATCAGGATCTGAACAGGCTCGATCGGGCGTGGGCGATTCCAGAAACCGTCATCGTACAGG
ATCCGGTGCGAACGGCGACGGTGGACCGGGCCGATATCGTGCTGCCAGCCTGCACGACGCTGGAGCGATGTGATATCGGC
GCCAGCCGCAGGTCCGACTATATCGTGGCCATGAAGAAGGTGGTCGATCCGATCGGCGAGGCACGTTCGGACTATGCGAT
CGTCTCGGAGATCGCGCGCGCGCTCGGCGTCGAAGCACAGTTCACCGAAGGCCGGGACGAAATGGGCTGGCTGCGCCATC
TCTACGAGAACAGCAGGACGGATGCAGCTGAGCGGCTTAATTGGGACATGCCCGCTTTCGACGAGTTCTGGACGCGGGGA
TGGGTTCAGGTTCCGATGCTTTCCAAGCAGGTCTATCTCGCGGATTTTCGCCAGGATCCCGAAAAGCATCCGCTGGGCAC
CGGTACCGGACGCATTATCCTTTCGAGCGAAACTCTCGAAACTCATGGTTATGATGACTTCCTGCCGTATCCGGCCTGGA
TCCCGCCTCGGCCTGAAGTGGGCCAAGGACCTTTGTACCTTCTGACACCTCAGCCCCAGGGGCGGCTCCATAGCCAGCTC
GACGGCGGCGTTGCGAGCCTTGCGGAAAAGACGGACGGCCTGGAGCGGCTGCGCATCAATACCACCGATGCGCGCGCGCT
GGGGATCGAGAGTGGCGTGACTGTCCTGATCAGAAACGATCGCGGCCGCTGTCTGGCCGCGGCCGATGTGTCCGACGACG
TCATGCCGGGTGTGGTGTGCCTGCCCACGGGATCGCGGCTTCAATTCGCCGCCGACGGTTCGGATCTGGAAATTTCGGGC
AATCCCAACGTGCTGACGGCGGACATACCCGCCTCCAGCTTCAGCCAGGGCTGTGCCGCCCAAAGCTGCCGCGTTTGGGT
GGAGCGCTGGAAGGCGCCTGAACATTCAGGGCTCGAAACGGGCCAAAGGGGGTCGAAGCATGAAAACGAGACATAA

Upstream 100 bases:

>100_bases
CAGCCGATTACGGCCGCGCTTGTGAACAGCGTCGCCGCTTGAGCTTTTTGGCTCCGTCTGACGAGGCGGAGCCAAAATTG
CCTATAGCCGGGGTATTACC

Downstream 100 bases:

>100_bases
GGCCGACGTAGCTATTATCGGCGGAGGTATCATCGGCCTGGCCATCGCTTACGAGCTCAAGATGAGAGGCTGTTCGCCGG
TCGTTCTTGAACGGGGCATC

Product: molybdopterin oxidoreductase

Products: Biotin [C]

Alternate protein names: BDS reductase; BSO reductase [H]

Number of amino acids: Translated: 771; Mature: 770

Protein sequence:

>771_residues
MGQAQKILHSSHWGIFFAVVENGRIVDIEPFKGDPAPSPLLASIPEWTNAETRVLRPMVREGWLRAHDAGRPQDNRDRRG
KDEFIEVSWPQAIELIASEINRVRTELGNSSIFAGSYGWTSAGRFHHAASQIKRLLNLVGGYTGHVDTYSIAAGPVLLRF
VLGNDFASGGRGTTLDTVVENTQTLLVFGALSPRTAQNEAGGVAKHKLEGYLRQIADRGIRVILISPCRDDVPEFLNAEW
WPIRPGTDAALLLALTRELVRSGRADLDFLNRYCSGSERFLSYLAGETDGQEKTAEWAEAITGIPGAAIRGLAPTIADTR
TMITLSWALQRADHGEQPYWAAIALAAAAGQIGLPGGGFGFGFGSVSGNGSPYGVIQAPALPQLKNPIRSFIPVARIADM
LLNPGQPFDYSGASYTYPDARLIYWAGGNPFHHHQDLNRLDRAWAIPETVIVQDPVRTATVDRADIVLPACTTLERCDIG
ASRRSDYIVAMKKVVDPIGEARSDYAIVSEIARALGVEAQFTEGRDEMGWLRHLYENSRTDAAERLNWDMPAFDEFWTRG
WVQVPMLSKQVYLADFRQDPEKHPLGTGTGRIILSSETLETHGYDDFLPYPAWIPPRPEVGQGPLYLLTPQPQGRLHSQL
DGGVASLAEKTDGLERLRINTTDARALGIESGVTVLIRNDRGRCLAAADVSDDVMPGVVCLPTGSRLQFAADGSDLEISG
NPNVLTADIPASSFSQGCAAQSCRVWVERWKAPEHSGLETGQRGSKHENET

Sequences:

>Translated_771_residues
MGQAQKILHSSHWGIFFAVVENGRIVDIEPFKGDPAPSPLLASIPEWTNAETRVLRPMVREGWLRAHDAGRPQDNRDRRG
KDEFIEVSWPQAIELIASEINRVRTELGNSSIFAGSYGWTSAGRFHHAASQIKRLLNLVGGYTGHVDTYSIAAGPVLLRF
VLGNDFASGGRGTTLDTVVENTQTLLVFGALSPRTAQNEAGGVAKHKLEGYLRQIADRGIRVILISPCRDDVPEFLNAEW
WPIRPGTDAALLLALTRELVRSGRADLDFLNRYCSGSERFLSYLAGETDGQEKTAEWAEAITGIPGAAIRGLAPTIADTR
TMITLSWALQRADHGEQPYWAAIALAAAAGQIGLPGGGFGFGFGSVSGNGSPYGVIQAPALPQLKNPIRSFIPVARIADM
LLNPGQPFDYSGASYTYPDARLIYWAGGNPFHHHQDLNRLDRAWAIPETVIVQDPVRTATVDRADIVLPACTTLERCDIG
ASRRSDYIVAMKKVVDPIGEARSDYAIVSEIARALGVEAQFTEGRDEMGWLRHLYENSRTDAAERLNWDMPAFDEFWTRG
WVQVPMLSKQVYLADFRQDPEKHPLGTGTGRIILSSETLETHGYDDFLPYPAWIPPRPEVGQGPLYLLTPQPQGRLHSQL
DGGVASLAEKTDGLERLRINTTDARALGIESGVTVLIRNDRGRCLAAADVSDDVMPGVVCLPTGSRLQFAADGSDLEISG
NPNVLTADIPASSFSQGCAAQSCRVWVERWKAPEHSGLETGQRGSKHENET
>Mature_770_residues
GQAQKILHSSHWGIFFAVVENGRIVDIEPFKGDPAPSPLLASIPEWTNAETRVLRPMVREGWLRAHDAGRPQDNRDRRGK
DEFIEVSWPQAIELIASEINRVRTELGNSSIFAGSYGWTSAGRFHHAASQIKRLLNLVGGYTGHVDTYSIAAGPVLLRFV
LGNDFASGGRGTTLDTVVENTQTLLVFGALSPRTAQNEAGGVAKHKLEGYLRQIADRGIRVILISPCRDDVPEFLNAEWW
PIRPGTDAALLLALTRELVRSGRADLDFLNRYCSGSERFLSYLAGETDGQEKTAEWAEAITGIPGAAIRGLAPTIADTRT
MITLSWALQRADHGEQPYWAAIALAAAAGQIGLPGGGFGFGFGSVSGNGSPYGVIQAPALPQLKNPIRSFIPVARIADML
LNPGQPFDYSGASYTYPDARLIYWAGGNPFHHHQDLNRLDRAWAIPETVIVQDPVRTATVDRADIVLPACTTLERCDIGA
SRRSDYIVAMKKVVDPIGEARSDYAIVSEIARALGVEAQFTEGRDEMGWLRHLYENSRTDAAERLNWDMPAFDEFWTRGW
VQVPMLSKQVYLADFRQDPEKHPLGTGTGRIILSSETLETHGYDDFLPYPAWIPPRPEVGQGPLYLLTPQPQGRLHSQLD
GGVASLAEKTDGLERLRINTTDARALGIESGVTVLIRNDRGRCLAAADVSDDVMPGVVCLPTGSRLQFAADGSDLEISGN
PNVLTADIPASSFSQGCAAQSCRVWVERWKAPEHSGLETGQRGSKHENET

Specific function: This enzyme may serve as a scavenger, allowing the cell to utilize biotin sulfoxide as a biotin source. It reduces a spontaneous oxidation product of biotin, D-biotin D-sulfoxide (BSO or BDS), back to biotin [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=773, Percent_Identity=37.51617076326, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI145693196, Length=768, Percent_Identity=36.0677083333333, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI1787231, Length=776, Percent_Identity=37.5, Blast_Score=417, Evalue=1e-117,
Organism=Escherichia coli, GI87081797, Length=715, Percent_Identity=31.4685314685315, Blast_Score=258, Evalue=8e-70,
Organism=Escherichia coli, GI171474008, Length=720, Percent_Identity=28.0555555555556, Blast_Score=222, Evalue=6e-59,
Organism=Escherichia coli, GI1787870, Length=725, Percent_Identity=28.1379310344828, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI3868721, Length=706, Percent_Identity=23.0878186968839, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.7.2.3 [C]

Molecular weight: Translated: 84255; Mature: 84124

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQAQKILHSSHWGIFFAVVENGRIVDIEPFKGDPAPSPLLASIPEWTNAETRVLRPMVR
CCHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCCCCCHHHCCCCCCCCHHHHHHHHHH
EGWLRAHDAGRPQDNRDRRGKDEFIEVSWPQAIELIASEINRVRTELGNSSIFAGSYGWT
HCCHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
SAGRFHHAASQIKRLLNLVGGYTGHVDTYSIAAGPVLLRFVLGNDFASGGRGTTLDTVVE
CCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHC
NTQTLLVFGALSPRTAQNEAGGVAKHKLEGYLRQIADRGIRVILISPCRDDVPEFLNAEW
CCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCC
WPIRPGTDAALLLALTRELVRSGRADLDFLNRYCSGSERFLSYLAGETDGQEKTAEWAEA
EECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHH
ITGIPGAAIRGLAPTIADTRTMITLSWALQRADHGEQPYWAAIALAAAAGQIGLPGGGFG
HHCCCCHHHHCCCCHHCCCCEEEEHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
FGFGSVSGNGSPYGVIQAPALPQLKNPIRSFIPVARIADMLLNPGQPFDYSGASYTYPDA
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCC
RLIYWAGGNPFHHHQDLNRLDRAWAIPETVIVQDPVRTATVDRADIVLPACTTLERCDIG
EEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCEEECCCCCHHHHCCC
ASRRSDYIVAMKKVVDPIGEARSDYAIVSEIARALGVEAQFTEGRDEMGWLRHLYENSRT
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHCCCC
DAAERLNWDMPAFDEFWTRGWVQVPMLSKQVYLADFRQDPEKHPLGTGTGRIILSSETLE
CHHHHCCCCCCCHHHHHCCCCEECCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCC
THGYDDFLPYPAWIPPRPEVGQGPLYLLTPQPQGRLHSQLDGGVASLAEKTDGLERLRIN
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHCCHHHHHHHHCCCCCEEEEC
TTDARALGIESGVTVLIRNDRGRCLAAADVSDDVMPGVVCLPTGSRLQFAADGSDLEISG
CCCCHHEECCCCCEEEEECCCCCEEEECCCCCCCCCCEEEECCCCCEEEEECCCEEEECC
NPNVLTADIPASSFSQGCAAQSCRVWVERWKAPEHSGLETGQRGSKHENET
CCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GQAQKILHSSHWGIFFAVVENGRIVDIEPFKGDPAPSPLLASIPEWTNAETRVLRPMVR
CHHHHHHHCCCCEEEEEEECCCEEEEEECCCCCCCCCCHHHCCCCCCCCHHHHHHHHHH
EGWLRAHDAGRPQDNRDRRGKDEFIEVSWPQAIELIASEINRVRTELGNSSIFAGSYGWT
HCCHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
SAGRFHHAASQIKRLLNLVGGYTGHVDTYSIAAGPVLLRFVLGNDFASGGRGTTLDTVVE
CCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHC
NTQTLLVFGALSPRTAQNEAGGVAKHKLEGYLRQIADRGIRVILISPCRDDVPEFLNAEW
CCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCC
WPIRPGTDAALLLALTRELVRSGRADLDFLNRYCSGSERFLSYLAGETDGQEKTAEWAEA
EECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHH
ITGIPGAAIRGLAPTIADTRTMITLSWALQRADHGEQPYWAAIALAAAAGQIGLPGGGFG
HHCCCCHHHHCCCCHHCCCCEEEEHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
FGFGSVSGNGSPYGVIQAPALPQLKNPIRSFIPVARIADMLLNPGQPFDYSGASYTYPDA
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCC
RLIYWAGGNPFHHHQDLNRLDRAWAIPETVIVQDPVRTATVDRADIVLPACTTLERCDIG
EEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCEEECCCCCHHHHCCC
ASRRSDYIVAMKKVVDPIGEARSDYAIVSEIARALGVEAQFTEGRDEMGWLRHLYENSRT
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHCCCC
DAAERLNWDMPAFDEFWTRGWVQVPMLSKQVYLADFRQDPEKHPLGTGTGRIILSSETLE
CHHHHCCCCCCCHHHHHCCCCEECCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCC
THGYDDFLPYPAWIPPRPEVGQGPLYLLTPQPQGRLHSQLDGGVASLAEKTDGLERLRIN
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHCCHHHHHHHHCCCCCEEEEC
TTDARALGIESGVTVLIRNDRGRCLAAADVSDDVMPGVVCLPTGSRLQFAADGSDLEISG
CCCCHHEECCCCCEEEEECCCCCEEEECCCCCCCCCCEEEECCCCCEEEEECCCEEEECC
NPNVLTADIPASSFSQGCAAQSCRVWVERWKAPEHSGLETGQRGSKHENET
CCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds) [C]

Specific reaction: Reduces A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds), Back To Biotin. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7733660 [H]