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The map label for this gene is namA [H]

Identifier: 110634965

GI number: 110634965

Start: 2839503

End: 2840759

Strand: Reverse

Name: namA [H]

Synonym: Meso_2631

Alternate gene names: 110634965

Gene position: 2840759-2839503 (Counterclockwise)

Preceding gene: 110634966

Following gene: 110634964

Centisome position: 64.38

GC content: 62.05

Gene sequence:

>1257_bases
ATGCGCAACACTAGCCAGGCAAGCATCGATCCTGCCACGCCCCTTCTGTTTTCTCCCCTGAGCCTTCGTTCGGTTCATCT
TAAGAACCGTATCGTTGTCGCGCCAATGTGCCAGTACCGATCGGTAGCGGGCGGGCCCACCGATTGGCACCTCGTCCATT
TGGGAAAGTTCGCGGTGGGCGGAGCCGGCATCGTCTTCACGGAGGAAACGGCCGTCGAGGAACGCGGACGGAAGACCTAC
GCCTGTGCCGGACTCTACAATGACGACCATGTGAAATCCTATCGCAGAATCACCGACTTCATCAGATCTCAAGGTGCCGT
ACCGGCCGTCCAACTGGGCCATGCCGGCCGCCAGGCATCGTGTCACGGGGCAGAGTTGGGATGGAAGCCTCTCACCGAGG
AGGATGCCCGGGCGGGACTGCCCCCTTGGCAGGGGGTGGCGCCGAGCCCTTTCGCCTGGTGCCCCGATGCCTCCGTTCCC
CATGAACTGTCGCATGCCGATATCAAGGACATGTTGGCCATATGGAAGGAGTCCACCCTCAGGGCCGTGGATTCGGGTTT
CGACATCTGTGAAATCCATGGTGGCCATGGCTATTTGCTGCACCAGTTCCTGTCCCCGCTGGCCAATAAGAGAACCGACG
CCTATGGCGGCGATCGCTCCGGGCGCATGCGGTTCGTGCTGGAGGTCACGGAGGCCGTCCGCTCGGCGTGGCCGGCGGAC
AAGCCGTTGTTTTTCCGCATGTCGGTGGTCGATGGGCGTGGCGGCCAATGGTTTGTGGAGGACAGCATTGCGCTTGCAGC
CGAGCTCCGCGAAATCGGCGTGGACCTTATAGACTGCTCGTCCGGCGGTATGAATGGCGATGGCGTCTTTCCACCCGTGC
CGCGCGTCCCCGAATTCCAGGTCGAATATTCCAAAGCCCTGCGGCACGGCGCCAGAATGCCGACCCTTGCCGTTGGCCTG
ATCACCAGCCCCCGCCGTGCCGAGGCCATTTTGCAGGCCGGCGAAGCCGATCTCATTGCCATCGCTCGCGGCGCCATATG
GGACCCGAATTGGCCGGCACATGCTGCGGCCGAGCTGGGCAAGCATGAGCCATATGCGGTCTTGCCCGGCGATATGGCGT
TCAGATTGCGCGATCGGGACAGCCACCGCGATAGCTATCCCTATGGCACAAAGGTAGACATTCCGCTCTCCCCGGACCGC
AGCATTCCCTATTCCTGGCCGGAACGTGGAGAATACTGGCCACCGGTCAGGGAATAA

Upstream 100 bases:

>100_bases
CACCAATCGATACGAGATCTTCTTTCAAAATCACCCGATCCGAGGCCCGGGACCGCCATCGATCGCATCTATGATGCCCT
TAAAGCCGGGAAGTTGGATA

Downstream 100 bases:

>100_bases
CTGGCAGCTCGGACACGCCGCAAGATGGACCTACCCACACTCACTATGGTGCACGCCGTCTTCGAAACAGGGTCCATACG
CCATGCCGGTCGGCTGATAG

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MRNTSQASIDPATPLLFSPLSLRSVHLKNRIVVAPMCQYRSVAGGPTDWHLVHLGKFAVGGAGIVFTEETAVEERGRKTY
ACAGLYNDDHVKSYRRITDFIRSQGAVPAVQLGHAGRQASCHGAELGWKPLTEEDARAGLPPWQGVAPSPFAWCPDASVP
HELSHADIKDMLAIWKESTLRAVDSGFDICEIHGGHGYLLHQFLSPLANKRTDAYGGDRSGRMRFVLEVTEAVRSAWPAD
KPLFFRMSVVDGRGGQWFVEDSIALAAELREIGVDLIDCSSGGMNGDGVFPPVPRVPEFQVEYSKALRHGARMPTLAVGL
ITSPRRAEAILQAGEADLIAIARGAIWDPNWPAHAAAELGKHEPYAVLPGDMAFRLRDRDSHRDSYPYGTKVDIPLSPDR
SIPYSWPERGEYWPPVRE

Sequences:

>Translated_418_residues
MRNTSQASIDPATPLLFSPLSLRSVHLKNRIVVAPMCQYRSVAGGPTDWHLVHLGKFAVGGAGIVFTEETAVEERGRKTY
ACAGLYNDDHVKSYRRITDFIRSQGAVPAVQLGHAGRQASCHGAELGWKPLTEEDARAGLPPWQGVAPSPFAWCPDASVP
HELSHADIKDMLAIWKESTLRAVDSGFDICEIHGGHGYLLHQFLSPLANKRTDAYGGDRSGRMRFVLEVTEAVRSAWPAD
KPLFFRMSVVDGRGGQWFVEDSIALAAELREIGVDLIDCSSGGMNGDGVFPPVPRVPEFQVEYSKALRHGARMPTLAVGL
ITSPRRAEAILQAGEADLIAIARGAIWDPNWPAHAAAELGKHEPYAVLPGDMAFRLRDRDSHRDSYPYGTKVDIPLSPDR
SIPYSWPERGEYWPPVRE
>Mature_418_residues
MRNTSQASIDPATPLLFSPLSLRSVHLKNRIVVAPMCQYRSVAGGPTDWHLVHLGKFAVGGAGIVFTEETAVEERGRKTY
ACAGLYNDDHVKSYRRITDFIRSQGAVPAVQLGHAGRQASCHGAELGWKPLTEEDARAGLPPWQGVAPSPFAWCPDASVP
HELSHADIKDMLAIWKESTLRAVDSGFDICEIHGGHGYLLHQFLSPLANKRTDAYGGDRSGRMRFVLEVTEAVRSAWPAD
KPLFFRMSVVDGRGGQWFVEDSIALAAELREIGVDLIDCSSGGMNGDGVFPPVPRVPEFQVEYSKALRHGARMPTLAVGL
ITSPRRAEAILQAGEADLIAIARGAIWDPNWPAHAAAELGKHEPYAVLPGDMAFRLRDRDSHRDSYPYGTKVDIPLSPDR
SIPYSWPERGEYWPPVRE

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=346, Percent_Identity=28.3236994219653, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1789463, Length=345, Percent_Identity=27.536231884058, Blast_Score=118, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI72001454, Length=371, Percent_Identity=24.7978436657682, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17565138, Length=360, Percent_Identity=25.8333333333333, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17559804, Length=246, Percent_Identity=28.4552845528455, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17564188, Length=269, Percent_Identity=25.2788104089219, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559802, Length=293, Percent_Identity=26.2798634812287, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=227, Percent_Identity=29.0748898678414, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321973, Length=231, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 45930; Mature: 45930

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNTSQASIDPATPLLFSPLSLRSVHLKNRIVVAPMCQYRSVAGGPTDWHLVHLGKFAVG
CCCCCCCCCCCCCCHHCCCCCHHEEECCCEEEEEEHHHHHHCCCCCCCEEEEEECCEEEC
GAGIVFTEETAVEERGRKTYACAGLYNDDHVKSYRRITDFIRSQGAVPAVQLGHAGRQAS
CCEEEEECHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCC
CHGAELGWKPLTEEDARAGLPPWQGVAPSPFAWCPDASVPHELSHADIKDMLAIWKESTL
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RAVDSGFDICEIHGGHGYLLHQFLSPLANKRTDAYGGDRSGRMRFVLEVTEAVRSAWPAD
HHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCC
KPLFFRMSVVDGRGGQWFVEDSIALAAELREIGVDLIDCSSGGMNGDGVFPPVPRVPEFQ
CCEEEEEEEEECCCCEEEEECHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCHH
VEYSKALRHGARMPTLAVGLITSPRRAEAILQAGEADLIAIARGAIWDPNWPAHAAAELG
HHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHC
KHEPYAVLPGDMAFRLRDRDSHRDSYPYGTKVDIPLSPDRSIPYSWPERGEYWPPVRE
CCCCEEECCCCEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRNTSQASIDPATPLLFSPLSLRSVHLKNRIVVAPMCQYRSVAGGPTDWHLVHLGKFAVG
CCCCCCCCCCCCCCHHCCCCCHHEEECCCEEEEEEHHHHHHCCCCCCCEEEEEECCEEEC
GAGIVFTEETAVEERGRKTYACAGLYNDDHVKSYRRITDFIRSQGAVPAVQLGHAGRQAS
CCEEEEECHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCC
CHGAELGWKPLTEEDARAGLPPWQGVAPSPFAWCPDASVPHELSHADIKDMLAIWKESTL
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RAVDSGFDICEIHGGHGYLLHQFLSPLANKRTDAYGGDRSGRMRFVLEVTEAVRSAWPAD
HHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCC
KPLFFRMSVVDGRGGQWFVEDSIALAAELREIGVDLIDCSSGGMNGDGVFPPVPRVPEFQ
CCEEEEEEEEECCCCEEEEECHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCHH
VEYSKALRHGARMPTLAVGLITSPRRAEAILQAGEADLIAIARGAIWDPNWPAHAAAELG
HHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHC
KHEPYAVLPGDMAFRLRDRDSHRDSYPYGTKVDIPLSPDRSIPYSWPERGEYWPPVRE
CCCCEEECCCCEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA