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The map label for this gene is allB [H]

Identifier: 110634885

GI number: 110634885

Start: 2725589

End: 2726968

Strand: Reverse

Name: allB [H]

Synonym: Meso_2544

Alternate gene names: 110634885

Gene position: 2726968-2725589 (Counterclockwise)

Preceding gene: 110634886

Following gene: 110634884

Centisome position: 61.8

GC content: 64.42

Gene sequence:

>1380_bases
ATGAGCGATTTCGACGTCGTCGTGACTGGACGTGTGGTTACGACGGACCGCGTCTACGAGGATGGTTATGTTGCGATACG
GGGCGGCCTGGTCGAACGGGTCGGCTCCGGCACGCCCCCGGCAGCGCGCGAGAAATACGATTTCGACGGCGACTACATTC
TGCCCGGGGCCATCGACGCTCAGGTCCACTCCCGTTCCCAACTCGACCAGGAAGATTTCCTCTGGTCCACCCGCTCGGCG
GCGGCCGGCGGTGTGACGACGATCGTCGACATGCCCTATGACGAGGGTTTCCTGGTGTGCACGGGCGAACGGCTGCAGCG
CAAGGCCGAGGAGGCGGCGCAGCAGTCGCGTGTCGATTTCGCGCTCTACGGCACGGTGCGGGCCCAGGACGGCGCCCGCG
AAATCGCCGGCATGGTGGAGGCCGGCGCAATCGGTTTCAAGTTTTCGACGTTCGAAACCGATCCTGAGCGCTTTCCGCGC
ATCGGGCCTGCCATTCTGCACGAATGTTTTTCCGAGATTGGGCGCTACGGCCTCATCGCAGGCATCCACAACGAGAATGA
CGAGATGGTGCGGCATGCGCTCGCCCAGGTCGCCGCGTCGGGCATCACGGATTATCGCGCCCATGCCATGTCGCGCCCGG
CTGCGGCCGAGACGCTTGCGATGGCGGAAGCCTACGAGCTAGGCGCGCAGGCCGGCTGCTCCACCCATGTCGTTCATTGT
TCCGTCGGGCGCGGTTACGAGCTTTGCGCCGGGTACCGCGCGCAGGGCTTCGATACCACGGTCGAGGCCTGCATCCATTA
TCTCACCCTCGATGAGGAAGATCATGTGCGGCGCTTCGGCGGCATGGCAAAGATCAACCCGCCTATTCGGCCTAGACGCG
AAGTGGAAGCCCTTTGGCGGCACCTGGCGGCGGGGAACGTTACCGTTGTCTCGACCGATCACGTTTCCTGGTCGATCGAC
CACAAGCGAAACCCTGAGATGTTGAAGAACAAGTCCGGCGTGCCAGGGCTGGAAGTACTTTACGCTCTGCTCATGAAGGG
GCTGGCCGAGCGCGGCTTGCCAATGACCTGGGCGGCGCGGCTTTTGGCCGCCAACCCGGCGCGGCTGTTCCGCATCGGAC
ATCGCAAGGGGGCGCTGGAACCAGGCCGTGACGCCGACATCGTGGTGATGCGGCACGATCCCAGGCGATACGATCCGGCG
GCAAGCGGAAACAATTTCGTCGACTGGAGCCCCTATGAGGGGATGGAACTGCCGTTCCGTCCCGTCGCCACCTTCCTGCG
CGGCCGTGTCGTCTTCGACGGCAGCGCAGTCGTCGCCCCAAGCGGAACCGGAACCTTCATACGCCCCCGCGGGGCCAATG
CCATTCAAATCGGCGCCTGA

Upstream 100 bases:

>100_bases
AGCTGGCGCGCGAGACCGGGATCGGCATAGCGGAGCAGCTTCAGACCTGATCGCCGGCCGCGTCTGCCGGGGGGTTTCCA
ACGAAAGGACTTCAAACAGC

Downstream 100 bases:

>100_bases
TCACAATGATCTTTCAATGGGAGTAACCTGAAATGTCTTTGAAAAGAAAATCTCTAGCGGCTGCGGCTTTGTTCCTGCTG
GCGGCCACCTCCAACGCCTC

Product: amidohydrolase

Products: NA

Alternate protein names: Allantoin-utilizing enzyme [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MSDFDVVVTGRVVTTDRVYEDGYVAIRGGLVERVGSGTPPAAREKYDFDGDYILPGAIDAQVHSRSQLDQEDFLWSTRSA
AAGGVTTIVDMPYDEGFLVCTGERLQRKAEEAAQQSRVDFALYGTVRAQDGAREIAGMVEAGAIGFKFSTFETDPERFPR
IGPAILHECFSEIGRYGLIAGIHNENDEMVRHALAQVAASGITDYRAHAMSRPAAAETLAMAEAYELGAQAGCSTHVVHC
SVGRGYELCAGYRAQGFDTTVEACIHYLTLDEEDHVRRFGGMAKINPPIRPRREVEALWRHLAAGNVTVVSTDHVSWSID
HKRNPEMLKNKSGVPGLEVLYALLMKGLAERGLPMTWAARLLAANPARLFRIGHRKGALEPGRDADIVVMRHDPRRYDPA
ASGNNFVDWSPYEGMELPFRPVATFLRGRVVFDGSAVVAPSGTGTFIRPRGANAIQIGA

Sequences:

>Translated_459_residues
MSDFDVVVTGRVVTTDRVYEDGYVAIRGGLVERVGSGTPPAAREKYDFDGDYILPGAIDAQVHSRSQLDQEDFLWSTRSA
AAGGVTTIVDMPYDEGFLVCTGERLQRKAEEAAQQSRVDFALYGTVRAQDGAREIAGMVEAGAIGFKFSTFETDPERFPR
IGPAILHECFSEIGRYGLIAGIHNENDEMVRHALAQVAASGITDYRAHAMSRPAAAETLAMAEAYELGAQAGCSTHVVHC
SVGRGYELCAGYRAQGFDTTVEACIHYLTLDEEDHVRRFGGMAKINPPIRPRREVEALWRHLAAGNVTVVSTDHVSWSID
HKRNPEMLKNKSGVPGLEVLYALLMKGLAERGLPMTWAARLLAANPARLFRIGHRKGALEPGRDADIVVMRHDPRRYDPA
ASGNNFVDWSPYEGMELPFRPVATFLRGRVVFDGSAVVAPSGTGTFIRPRGANAIQIGA
>Mature_458_residues
SDFDVVVTGRVVTTDRVYEDGYVAIRGGLVERVGSGTPPAAREKYDFDGDYILPGAIDAQVHSRSQLDQEDFLWSTRSAA
AGGVTTIVDMPYDEGFLVCTGERLQRKAEEAAQQSRVDFALYGTVRAQDGAREIAGMVEAGAIGFKFSTFETDPERFPRI
GPAILHECFSEIGRYGLIAGIHNENDEMVRHALAQVAASGITDYRAHAMSRPAAAETLAMAEAYELGAQAGCSTHVVHCS
VGRGYELCAGYRAQGFDTTVEACIHYLTLDEEDHVRRFGGMAKINPPIRPRREVEALWRHLAAGNVTVVSTDHVSWSIDH
KRNPEMLKNKSGVPGLEVLYALLMKGLAERGLPMTWAARLLAANPARLFRIGHRKGALEPGRDADIVVMRHDPRRYDPAA
SGNNFVDWSPYEGMELPFRPVATFLRGRVVFDGSAVVAPSGTGTFIRPRGANAIQIGA

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503379, Length=463, Percent_Identity=23.3261339092873, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI4503051, Length=468, Percent_Identity=24.5726495726496, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI4503375, Length=461, Percent_Identity=26.2472885032538, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI62422571, Length=468, Percent_Identity=24.5726495726496, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI4503377, Length=468, Percent_Identity=23.9316239316239, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI190194363, Length=469, Percent_Identity=25.7995735607676, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI19923821, Length=464, Percent_Identity=25, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI18105007, Length=405, Percent_Identity=27.1604938271605, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI87082175, Length=466, Percent_Identity=30.4721030042918, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1786722, Length=460, Percent_Identity=26.9565217391304, Blast_Score=147, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17539558, Length=472, Percent_Identity=25.4237288135593, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71989490, Length=473, Percent_Identity=25.369978858351, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193204318, Length=404, Percent_Identity=25, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6322218, Length=399, Percent_Identity=26.8170426065163, Blast_Score=120, Evalue=4e-28,
Organism=Drosophila melanogaster, GI221377917, Length=474, Percent_Identity=27.0042194092827, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24642586, Length=430, Percent_Identity=27.6744186046512, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI17137462, Length=458, Percent_Identity=25.1091703056769, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI18859883, Length=413, Percent_Identity=27.6029055690073, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR004722
- InterPro:   IPR002195
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.5 [H]

Molecular weight: Translated: 50094; Mature: 49963

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFDVVVTGRVVTTDRVYEDGYVAIRGGLVERVGSGTPPAAREKYDFDGDYILPGAIDA
CCCCEEEEEEEEEEECEEECCCEEEEECHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCH
QVHSRSQLDQEDFLWSTRSAAAGGVTTIVDMPYDEGFLVCTGERLQRKAEEAAQQSRVDF
HHHHHHCCCHHHHHCCCCCCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHHHCCCE
ALYGTVRAQDGAREIAGMVEAGAIGFKFSTFETDPERFPRIGPAILHECFSEIGRYGLIA
EEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCHHHCCCCCHHHHHHHHHHHCCCEEEE
GIHNENDEMVRHALAQVAASGITDYRAHAMSRPAAAETLAMAEAYELGAQAGCSTHVVHC
EECCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
SVGRGYELCAGYRAQGFDTTVEACIHYLTLDEEDHVRRFGGMAKINPPIRPRREVEALWR
ECCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCEECCCCCCCHHHHHHHHH
HLAAGNVTVVSTDHVSWSIDHKRNPEMLKNKSGVPGLEVLYALLMKGLAERGLPMTWAAR
HHHCCCEEEEEECCEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
LLAANPARLFRIGHRKGALEPGRDADIVVMRHDPRRYDPAASGNNFVDWSPYEGMELPFR
HHHCCHHHHHEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHH
PVATFLRGRVVFDGSAVVAPSGTGTFIRPRGANAIQIGA
HHHHHHCCEEEECCCEEEECCCCCCEEECCCCCEEEECC
>Mature Secondary Structure 
SDFDVVVTGRVVTTDRVYEDGYVAIRGGLVERVGSGTPPAAREKYDFDGDYILPGAIDA
CCCEEEEEEEEEEECEEECCCEEEEECHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCH
QVHSRSQLDQEDFLWSTRSAAAGGVTTIVDMPYDEGFLVCTGERLQRKAEEAAQQSRVDF
HHHHHHCCCHHHHHCCCCCCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHHHCCCE
ALYGTVRAQDGAREIAGMVEAGAIGFKFSTFETDPERFPRIGPAILHECFSEIGRYGLIA
EEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCHHHCCCCCHHHHHHHHHHHCCCEEEE
GIHNENDEMVRHALAQVAASGITDYRAHAMSRPAAAETLAMAEAYELGAQAGCSTHVVHC
EECCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
SVGRGYELCAGYRAQGFDTTVEACIHYLTLDEEDHVRRFGGMAKINPPIRPRREVEALWR
ECCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCEECCCCCCCHHHHHHHHH
HLAAGNVTVVSTDHVSWSIDHKRNPEMLKNKSGVPGLEVLYALLMKGLAERGLPMTWAAR
HHHCCCEEEEEECCEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
LLAANPARLFRIGHRKGALEPGRDADIVVMRHDPRRYDPAASGNNFVDWSPYEGMELPFR
HHHCCHHHHHEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHH
PVATFLRGRVVFDGSAVVAPSGTGTFIRPRGANAIQIGA
HHHHHHCCEEEECCCEEEECCCCCCEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA