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The map label for this gene is dppB [H]

Identifier: 110634749

GI number: 110634749

Start: 2565067

End: 2565987

Strand: Reverse

Name: dppB [H]

Synonym: Meso_2407

Alternate gene names: 110634749

Gene position: 2565987-2565067 (Counterclockwise)

Preceding gene: 110634750

Following gene: 110634748

Centisome position: 58.15

GC content: 64.17

Gene sequence:

>921_bases
TTGGCCGATTTCCTGATTTCCCGATTGCTATATGCCGCGGCGGTGCTGCTCGGCGTCTCCGTCGCCGTGTTCTTCCTGAT
CCGGATCGGCGGCGATCCCTCGGCGTTGTTCCTGCCGCCGGAGGCCCCGGTCGAGGAAATAGAGCGGTTCCGTCGGCTGA
TGGGCTTCGACCGGCCGTTGGCGGTGCAGTATTTCGACTTCCTCGGCCGCGCGCTCCAGGGCGACTTCGGCATGTCGCTT
CGATATGACCAGCCGGCGATGAAGCTGGTGCTGGAGCGCGTGCCGGCCACGCTCCAGCTGGGCGCGATGGCGCTGCTGAT
GTCGCTCGTTATCTCAATCCCGCTGGCCATCCTCGCTGCTGCCAAGCATGGCTCGGCGATCGACAGAGCAAGCCTGCTTG
CCTCGCTGCTCGGCCAGAGCTTTCCCGCATTCTGGCTGGCAATCATGCTGATCTTGCTGTTCTCCGAAACGTTCCGGTTG
CTGCCGCCATCGGGGCGGGGAACGTGGCAGCAGCTGATCATGCCAGCGATCGTGCTCGCCACATACTCGACCGCCATCAT
CACGCGCCTGTTGCGCTCTTCGATGATCGAGGTGCTGCAGTCGGACTATGTCCGCACCGCGCGCGGCAAGGGCGTGAAGG
AAAGCCGCATCATCCTCTCCCACGCGCTGCGCAACGCGGCCATCCCCACGCTGACAGTGATCGGGCTCCAGGTCGGCGCG
CTGCTGGGCGGCGCCGTAATCACCGAGGAGGTGTTTGCCTATCCCGGAGTGGGCCGTCTGGCGATCCAGGCCATCGCCAA
CCGCGATTTTACCGTGGTGCAGGCGTTCGTGGTCCTGATGGCGGCGCTGATCGTGACCATCAACCTCCTGGTAGACCTCT
CTTACGGCCTGCTCGATCCGCGACTGAGGAAGGGCAAATGA

Upstream 100 bases:

>100_bases
GCAAGGCGCATTTCTAGGCTTTCGCACCGACATCCACCGGCCGGTATCGATCCGGCCGGTGAGCATCCGTACTCGTGTCT
GCCATGGAGTGGAGCAGGCG

Downstream 100 bases:

>100_bases
GGGACTTTCTCAAACGCTATTCATCGAGCAGCCTCGCCATGGTCGGCCTGGCGATCGTGCTGGTCGCGGTGTTCGCGGCG
GCGTTCGGCCCATGGCTGGT

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MADFLISRLLYAAAVLLGVSVAVFFLIRIGGDPSALFLPPEAPVEEIERFRRLMGFDRPLAVQYFDFLGRALQGDFGMSL
RYDQPAMKLVLERVPATLQLGAMALLMSLVISIPLAILAAAKHGSAIDRASLLASLLGQSFPAFWLAIMLILLFSETFRL
LPPSGRGTWQQLIMPAIVLATYSTAIITRLLRSSMIEVLQSDYVRTARGKGVKESRIILSHALRNAAIPTLTVIGLQVGA
LLGGAVITEEVFAYPGVGRLAIQAIANRDFTVVQAFVVLMAALIVTINLLVDLSYGLLDPRLRKGK

Sequences:

>Translated_306_residues
MADFLISRLLYAAAVLLGVSVAVFFLIRIGGDPSALFLPPEAPVEEIERFRRLMGFDRPLAVQYFDFLGRALQGDFGMSL
RYDQPAMKLVLERVPATLQLGAMALLMSLVISIPLAILAAAKHGSAIDRASLLASLLGQSFPAFWLAIMLILLFSETFRL
LPPSGRGTWQQLIMPAIVLATYSTAIITRLLRSSMIEVLQSDYVRTARGKGVKESRIILSHALRNAAIPTLTVIGLQVGA
LLGGAVITEEVFAYPGVGRLAIQAIANRDFTVVQAFVVLMAALIVTINLLVDLSYGLLDPRLRKGK
>Mature_305_residues
ADFLISRLLYAAAVLLGVSVAVFFLIRIGGDPSALFLPPEAPVEEIERFRRLMGFDRPLAVQYFDFLGRALQGDFGMSLR
YDQPAMKLVLERVPATLQLGAMALLMSLVISIPLAILAAAKHGSAIDRASLLASLLGQSFPAFWLAIMLILLFSETFRLL
PPSGRGTWQQLIMPAIVLATYSTAIITRLLRSSMIEVLQSDYVRTARGKGVKESRIILSHALRNAAIPTLTVIGLQVGAL
LGGAVITEEVFAYPGVGRLAIQAIANRDFTVVQAFVVLMAALIVTINLLVDLSYGLLDPRLRKGK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=341, Percent_Identity=39.2961876832845, Blast_Score=236, Evalue=1e-63,
Organism=Escherichia coli, GI1789888, Length=312, Percent_Identity=40.3846153846154, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1787053, Length=304, Percent_Identity=38.8157894736842, Blast_Score=227, Evalue=8e-61,
Organism=Escherichia coli, GI1787497, Length=309, Percent_Identity=33.0097087378641, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1787761, Length=321, Percent_Identity=37.6947040498442, Blast_Score=170, Evalue=9e-44,
Organism=Escherichia coli, GI1787550, Length=264, Percent_Identity=31.4393939393939, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788504, Length=285, Percent_Identity=30.5263157894737, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33248; Mature: 33117

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFLISRLLYAAAVLLGVSVAVFFLIRIGGDPSALFLPPEAPVEEIERFRRLMGFDRPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCH
AVQYFDFLGRALQGDFGMSLRYDQPAMKLVLERVPATLQLGAMALLMSLVISIPLAILAA
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
AKHGSAIDRASLLASLLGQSFPAFWLAIMLILLFSETFRLLPPSGRGTWQQLIMPAIVLA
HHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
TYSTAIITRLLRSSMIEVLQSDYVRTARGKGVKESRIILSHALRNAAIPTLTVIGLQVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LLGGAVITEEVFAYPGVGRLAIQAIANRDFTVVQAFVVLMAALIVTINLLVDLSYGLLDP
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RLRKGK
HHCCCC
>Mature Secondary Structure 
ADFLISRLLYAAAVLLGVSVAVFFLIRIGGDPSALFLPPEAPVEEIERFRRLMGFDRPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCH
AVQYFDFLGRALQGDFGMSLRYDQPAMKLVLERVPATLQLGAMALLMSLVISIPLAILAA
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
AKHGSAIDRASLLASLLGQSFPAFWLAIMLILLFSETFRLLPPSGRGTWQQLIMPAIVLA
HHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
TYSTAIITRLLRSSMIEVLQSDYVRTARGKGVKESRIILSHALRNAAIPTLTVIGLQVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LLGGAVITEEVFAYPGVGRLAIQAIANRDFTVVQAFVVLMAALIVTINLLVDLSYGLLDP
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RLRKGK
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]