Click here to switch to the map view.

The map label for this gene is appC [H]

Identifier: 110634748

GI number: 110634748

Start: 2564216

End: 2565070

Strand: Reverse

Name: appC [H]

Synonym: Meso_2406

Alternate gene names: 110634748

Gene position: 2565070-2564216 (Counterclockwise)

Preceding gene: 110634749

Following gene: 110634747

Centisome position: 58.13

GC content: 63.04

Gene sequence:

>855_bases
ATGAGGGACTTTCTCAAACGCTATTCATCGAGCAGCCTCGCCATGGTCGGCCTGGCGATCGTGCTGGTCGCGGTGTTCGC
GGCGGCGTTCGGCCCATGGCTGGTGCCTTTCGACCCCAATACGCAGGACATCCTGCAACGCCTCAAGCCACCCCTGTGGC
GGGGAACCGATGGAATGCACCTCCTGGGCACGGACGCGCTCGGCCGCGACATTTTCAGCCGCATCATCGTCGGCGCGCGC
GTGTCGATCCTCGTCGGTGTCAGCGCCGTGGTCATATCCAGCATCGTCGGCGTCACCTTCGGCCTGATCGCCGGCTACGA
GGACAAATATGCCGGCCGCGTGCTGATGATGCTCACCGATATCCAGCTCGCCATCCCCTTCATGGTCCTCGCTCTCGCCG
TGGCGGCGGTGGTTGGGCCGAGCTTGTGGAACATCATCGCGATACTGGGCCTGACGAACTGGGTTCAATATGCCCGCGTC
GTGCGCGCCGAATGCCTCGTGTTGCGCGAACGCGAATTCGTGCAGGCCGCGCACATGATGGGCATCTCGACGCCCCATAT
CCTGACGCGCCACCTTCTGCCAAACGTGATGTCTTCGGTGATCGTTATATCGAGCCTGCTGGTCGCGAAGATGATCATCT
TCGAATCCTCTCTGAGCTTTCTCGGCCTCGGCGTTCCGCCCGCGACCCCCACCTGGGGCACGATGATTGCCGAGGGGCGC
AACTACATCGGCAATGCGTGGTGGGTGGCCACCATTCCGGGCGTCGCCATCTTCGTCACCGTAATGGGCACCAATCTGGT
CGGCGACCGGTTGCGCGACCTGCTCGATCCGCGGTTGCGCCAGGTGGAATCCTGA

Upstream 100 bases:

>100_bases
TGCAGGCGTTCGTGGTCCTGATGGCGGCGCTGATCGTGACCATCAACCTCCTGGTAGACCTCTCTTACGGCCTGCTCGAT
CCGCGACTGAGGAAGGGCAA

Downstream 100 bases:

>100_bases
CATGACCGAGGCCAGCTATGAGATACTCATGCCGGGCTTTCCTGGGCGCAGCTCCCGCGGTTTCCTCGGCTGGAGCACGA
TCCTGCTGCTGAAAACCGCC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MRDFLKRYSSSSLAMVGLAIVLVAVFAAAFGPWLVPFDPNTQDILQRLKPPLWRGTDGMHLLGTDALGRDIFSRIIVGAR
VSILVGVSAVVISSIVGVTFGLIAGYEDKYAGRVLMMLTDIQLAIPFMVLALAVAAVVGPSLWNIIAILGLTNWVQYARV
VRAECLVLREREFVQAAHMMGISTPHILTRHLLPNVMSSVIVISSLLVAKMIIFESSLSFLGLGVPPATPTWGTMIAEGR
NYIGNAWWVATIPGVAIFVTVMGTNLVGDRLRDLLDPRLRQVES

Sequences:

>Translated_284_residues
MRDFLKRYSSSSLAMVGLAIVLVAVFAAAFGPWLVPFDPNTQDILQRLKPPLWRGTDGMHLLGTDALGRDIFSRIIVGAR
VSILVGVSAVVISSIVGVTFGLIAGYEDKYAGRVLMMLTDIQLAIPFMVLALAVAAVVGPSLWNIIAILGLTNWVQYARV
VRAECLVLREREFVQAAHMMGISTPHILTRHLLPNVMSSVIVISSLLVAKMIIFESSLSFLGLGVPPATPTWGTMIAEGR
NYIGNAWWVATIPGVAIFVTVMGTNLVGDRLRDLLDPRLRQVES
>Mature_284_residues
MRDFLKRYSSSSLAMVGLAIVLVAVFAAAFGPWLVPFDPNTQDILQRLKPPLWRGTDGMHLLGTDALGRDIFSRIIVGAR
VSILVGVSAVVISSIVGVTFGLIAGYEDKYAGRVLMMLTDIQLAIPFMVLALAVAAVVGPSLWNIIAILGLTNWVQYARV
VRAECLVLREREFVQAAHMMGISTPHILTRHLLPNVMSSVIVISSLLVAKMIIFESSLSFLGLGVPPATPTWGTMIAEGR
NYIGNAWWVATIPGVAIFVTVMGTNLVGDRLRDLLDPRLRQVES

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=270, Percent_Identity=38.8888888888889, Blast_Score=204, Evalue=5e-54,
Organism=Escherichia coli, GI1787054, Length=279, Percent_Identity=38.7096774193548, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1789964, Length=282, Percent_Identity=40.7801418439716, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1789889, Length=251, Percent_Identity=38.2470119521912, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1787498, Length=281, Percent_Identity=35.5871886120996, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788505, Length=224, Percent_Identity=32.5892857142857, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787549, Length=273, Percent_Identity=31.5018315018315, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30865; Mature: 30865

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHCHHHHHCCC
>Mature Secondary Structure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CCCCCEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]