Click here to switch to the map view.

The map label for this gene is dnaQ [H]

Identifier: 110634574

GI number: 110634574

Start: 2374306

End: 2375802

Strand: Reverse

Name: dnaQ [H]

Synonym: Meso_2226

Alternate gene names: 110634574

Gene position: 2375802-2374306 (Counterclockwise)

Preceding gene: 110634575

Following gene: 110634572

Centisome position: 53.84

GC content: 66.93

Gene sequence:

>1497_bases
GTGCAGCCTGATGTCGGAGCGATTCCGCTGATCGCGCTCGATGCGGTGGCTTTCGACACGGAGACCACCGGCCTCGATAC
GCGCACGGCACGCGTCGTCCAGGTCGCAGGTGTGGCGATCTCGCGCGGCGCGGTGCGTCAGGACGAGTCCTTCGAAAGCC
TTGTCCATCCAGGTATGTCCATCCCGCCCGACTCGATACGCATCCATGGCATCACCGATGGGATGCTGCGTGAGGCGCCA
GCCTTCGCTGCCGTCTGGCGCAGCTTCGAGATGTTCCGCGGGGTGCGGCCTCTGATCGGCTATGCTGTCGGCTTCGATCT
GGCGATCATCGAGAGGGAAGCGGCGCGGGCCGGGATCCGGAGGAAGCGGCCGCGGACCTTGTGCGTGCGAACGCTGAGCC
GCATCGTCAACCGCGATCTGCGCGGCCACTCGCTCGAGGCGCTCGCCGCCTGGCTGGGGTTCGAGATCATCGGTCGCCAT
CAGGCGCTCGACGACGCGATGGCCGCAGCGAAAGTGTTCACGGGACTCCTGCCGAGGCTGCAGGCCATGGGCATTCGCAC
CTTTGCCGAGGCGGAGCGGGCCTCCCTCCAGCTTGCACGGGAGCAGGACGAGCAGGCAAAGGCCGGATGGGCGGATCCCT
TCCTGCGGCCGGTCCCGCAACCCTTTGCCGCGATCGACCCCTTTGCCTACCAGCATCGCGTCGGCGATCTCATGGCTACG
CCTCCTATCTTCGTCCGCCATGAAACATCGCTCCGCTCGGTGATCGGGCTAATGGCAGAGAGGCGGGTGGGCTCCGTCCT
GGTCTCCGGCGCGGGGGAGGTGGGACATCCCACAGGCGCATACGGCATCCTCACGGAGCGCGACGTGCTTCGCTTGCTGG
CGGCCGACGGCGGGAATGTTTTCGAGCGACTCACCGGCGAGCTCGCAAGCAGGCCGCTCATCAGCATCCGCGCCCAGGCC
TTCGCCTATCGCGCGATCGGCCGGATGAACAGGCTCGGGATTCGCCATCTCGGTGTGCATGACGATGATGGTGGTCTCGT
CGGCGTGATATCCGCGCGCGATCTCCTGCGCCTGCGGGCAAGCGCGGCGATCCAGCTCGACGACGCGATCGACGCCGCAA
GGTCCGATGCCGACATGGCCGCCGCCTGGGCCTCTCTTCCCTCCGTTGCGTCGGTACTGGTGGCAGAGAAGATCGAAGCG
CGGACCGTTGCCGAGATCGTCAGCGAGGAACTGCGCGCCATCACGCGTCGGGCGGCGATCCTTGCGGAAGAGGAAATGAA
GATTGTCGGTCTGGGCGACCCACCCTCACGCTATGCCGTACTTGTTCTTGGTTCCGCCGGGCGGGCGAGAGCCTGCTTGC
CGCCGACCAGGACAATGCCATCGTTTTCGAGCGGGGCGCGCCGGGCGGGCCGGAGGATCGGTGGTTCGGCGCCCTTGGTG
GGCGGATCGCTGCCATTCTCGATACGGCCGGGATCGCCTATTGCAAGGGCGGCGTGA

Upstream 100 bases:

>100_bases
CCGGCTCGGGGAGCGGGCAGCCTGAACCCCATACCTGGTGTTCTTCGCGGCTCGAAACGGCGGTACACGGTATAAGCCGT
CTGAAGAGGGGAGGGCTTGC

Downstream 100 bases:

>100_bases
TGGCGAAAAACGCGGAATGGCGCGGCTCGCTGGATCTCTGGAGGGAGCGCATCAGTCAGTGGGTGCGCCGCTCGCGCCCT
CAGGATCTGCTCAACATCGA

Product: DNA polymerase III, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MQPDVGAIPLIALDAVAFDTETTGLDTRTARVVQVAGVAISRGAVRQDESFESLVHPGMSIPPDSIRIHGITDGMLREAP
AFAAVWRSFEMFRGVRPLIGYAVGFDLAIIEREAARAGIRRKRPRTLCVRTLSRIVNRDLRGHSLEALAAWLGFEIIGRH
QALDDAMAAAKVFTGLLPRLQAMGIRTFAEAERASLQLAREQDEQAKAGWADPFLRPVPQPFAAIDPFAYQHRVGDLMAT
PPIFVRHETSLRSVIGLMAERRVGSVLVSGAGEVGHPTGAYGILTERDVLRLLAADGGNVFERLTGELASRPLISIRAQA
FAYRAIGRMNRLGIRHLGVHDDDGGLVGVISARDLLRLRASAAIQLDDAIDAARSDADMAAAWASLPSVASVLVAEKIEA
RTVAEIVSEELRAITRRAAILAEEEMKIVGLGDPPSRYAVLVLGSAGRARACLPPTRTMPSFSSGARRAGRRIGGSAPLV
GGSLPFSIRPGSPIARAA

Sequences:

>Translated_498_residues
MQPDVGAIPLIALDAVAFDTETTGLDTRTARVVQVAGVAISRGAVRQDESFESLVHPGMSIPPDSIRIHGITDGMLREAP
AFAAVWRSFEMFRGVRPLIGYAVGFDLAIIEREAARAGIRRKRPRTLCVRTLSRIVNRDLRGHSLEALAAWLGFEIIGRH
QALDDAMAAAKVFTGLLPRLQAMGIRTFAEAERASLQLAREQDEQAKAGWADPFLRPVPQPFAAIDPFAYQHRVGDLMAT
PPIFVRHETSLRSVIGLMAERRVGSVLVSGAGEVGHPTGAYGILTERDVLRLLAADGGNVFERLTGELASRPLISIRAQA
FAYRAIGRMNRLGIRHLGVHDDDGGLVGVISARDLLRLRASAAIQLDDAIDAARSDADMAAAWASLPSVASVLVAEKIEA
RTVAEIVSEELRAITRRAAILAEEEMKIVGLGDPPSRYAVLVLGSAGRARACLPPTRTMPSFSSGARRAGRRIGGSAPLV
GGSLPFSIRPGSPIARAA
>Mature_498_residues
MQPDVGAIPLIALDAVAFDTETTGLDTRTARVVQVAGVAISRGAVRQDESFESLVHPGMSIPPDSIRIHGITDGMLREAP
AFAAVWRSFEMFRGVRPLIGYAVGFDLAIIEREAARAGIRRKRPRTLCVRTLSRIVNRDLRGHSLEALAAWLGFEIIGRH
QALDDAMAAAKVFTGLLPRLQAMGIRTFAEAERASLQLAREQDEQAKAGWADPFLRPVPQPFAAIDPFAYQHRVGDLMAT
PPIFVRHETSLRSVIGLMAERRVGSVLVSGAGEVGHPTGAYGILTERDVLRLLAADGGNVFERLTGELASRPLISIRAQA
FAYRAIGRMNRLGIRHLGVHDDDGGLVGVISARDLLRLRASAAIQLDDAIDAARSDADMAAAWASLPSVASVLVAEKIEA
RTVAEIVSEELRAITRRAAILAEEEMKIVGLGDPPSRYAVLVLGSAGRARACLPPTRTMPSFSSGARRAGRRIGGSAPLV
GGSLPFSIRPGSPIARAA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR000014
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 53341; Mature: 53341

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPDVGAIPLIALDAVAFDTETTGLDTRTARVVQVAGVAISRGAVRQDESFESLVHPGMS
CCCCCCCCHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
IPPDSIRIHGITDGMLREAPAFAAVWRSFEMFRGVRPLIGYAVGFDLAIIEREAARAGIR
CCCCCEEEEECCCHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHH
RKRPRTLCVRTLSRIVNRDLRGHSLEALAAWLGFEIIGRHQALDDAMAAAKVFTGLLPRL
HCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAMGIRTFAEAERASLQLAREQDEQAKAGWADPFLRPVPQPFAAIDPFAYQHRVGDLMAT
HHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHCCCHHHHHHHHHHHCC
PPIFVRHETSLRSVIGLMAERRVGSVLVSGAGEVGHPTGAYGILTERDVLRLLAADGGNV
CCEEEECCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCHH
FERLTGELASRPLISIRAQAFAYRAIGRMNRLGIRHLGVHDDDGGLVGVISARDLLRLRA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCEEEEECHHHHHHHHH
SAAIQLDDAIDAARSDADMAAAWASLPSVASVLVAEKIEARTVAEIVSEELRAITRRAAI
HHHEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAEEEMKIVGLGDPPSRYAVLVLGSAGRARACLPPTRTMPSFSSGARRAGRRIGGSAPLV
HHHCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEE
GGSLPFSIRPGSPIARAA
CCCCCEEECCCCCHHCCC
>Mature Secondary Structure
MQPDVGAIPLIALDAVAFDTETTGLDTRTARVVQVAGVAISRGAVRQDESFESLVHPGMS
CCCCCCCCHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
IPPDSIRIHGITDGMLREAPAFAAVWRSFEMFRGVRPLIGYAVGFDLAIIEREAARAGIR
CCCCCEEEEECCCHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHH
RKRPRTLCVRTLSRIVNRDLRGHSLEALAAWLGFEIIGRHQALDDAMAAAKVFTGLLPRL
HCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAMGIRTFAEAERASLQLAREQDEQAKAGWADPFLRPVPQPFAAIDPFAYQHRVGDLMAT
HHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHCCCHHHHHHHHHHHCC
PPIFVRHETSLRSVIGLMAERRVGSVLVSGAGEVGHPTGAYGILTERDVLRLLAADGGNV
CCEEEECCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCHH
FERLTGELASRPLISIRAQAFAYRAIGRMNRLGIRHLGVHDDDGGLVGVISARDLLRLRA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCEEEEECHHHHHHHHH
SAAIQLDDAIDAARSDADMAAAWASLPSVASVLVAEKIEARTVAEIVSEELRAITRRAAI
HHHEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAEEEMKIVGLGDPPSRYAVLVLGSAGRARACLPPTRTMPSFSSGARRAGRRIGGSAPLV
HHHCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEE
GGSLPFSIRPGSPIARAA
CCCCCEEECCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9256491 [H]