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The map label for this gene is ygjG [C]

Identifier: 110634392

GI number: 110634392

Start: 2193659

End: 2194984

Strand: Direct

Name: ygjG [C]

Synonym: Meso_2042

Alternate gene names: 110634392

Gene position: 2193659-2194984 (Clockwise)

Preceding gene: 110634387

Following gene: 110634393

Centisome position: 49.72

GC content: 61.09

Gene sequence:

>1326_bases
ATGCTTGAGCGACCCAAAAGACCGAATGATCTCAGCGCATTCTGGATGCCGTTCACGGCCAACCGGCAGTTCAAGCAGGC
GCCGCGTATGCTCGTCTCGGCCAAGGATATGCATTATACGACCGATGACGGCCGCAAGCTTCTCGACGGCACGGCGGGGC
TGTGGTGCGTCAATGCCGGCCACTGCCGGCCGAAAATCACGGAAGCCATCAGGCATCAGGCGGGCGAGCTGGACTATGCT
CCTGCCTTCCAGATGGGTCATCCCATCGTCTTCGAATTCGCAAGCCGTCTGGTGGATATCGCGCCGGAAGGCATGGATCA
TGTCTTCTTCACCAATTCCGGGTCGGAGTCCGTCGAGACTGCGCTGAAGATCGCCCTTGCCTATCACCGGGCGAAGGGTG
ACGGCTCGCGCACGCGTCTCATCGGCCGCGAGCGCGGCTATCACGGGGTTAATTTCGGCGGCATTTCCGTTGGCGGCATC
GTCAACAACCGCAAGATGTTCGGCACGCTTTTGGCCGGCGTAGACCACCTGCCGCACACATACCTGCCGGGGAAGAACGC
CTTCTCACGCGGCGTGCCTGAGCATGGGGTGGAGCTTGCCGACGAGTTGGAGCGGATCGTGGCGCTTCACGATGCCTCCA
CCATCGCCGCCGTCATCGTCGAGCCGGTGGCCGGGTCTGCCGGCGTGATCCTGCCGCCCAAGGGCTATCTGAAGCGGCTC
CGAGAGATCTGCGACAAGCACGGCATCCTGCTCATCTTCGATGAAGTCATCACAGGCTTTGGCCGCCTGGGCACGCCCTT
TGCGGCCGATTATTTCGGCGTGGTGCCCGATATCATGACGACGGCCAAGGGTATCACCAACGGCGTGATCCCGATGGGCG
CGGTGTTCGTGAAGAAGGAGATCCACGACGCCTTCATGAACGGCCCGGAGCACATGATCGAGTTCTTCCACGGCTATACC
TATTCGGGCAACCCGATCGCCTGCGCCGCCGGCCTCGCTACCCTCGAAACCTACAGGGAGGAAGGCCTGCTCACGCGCGG
CGAGGAATTGGGCCAGCACTGGGAGGATGCGCTGCATTCGCTCAAGGGCGAGCCGCATGTGATCGACATCCGCAATATCG
GCCTTGTCGGCGCGATCGAAATGGAGCCGATACAAGGCCAGCCCACCAAGCGCGCCTTCTCCGCCTTCCTGAAGGGCTTC
GAGAAGGGGCTGTTGATACGCACGACCGGCGACATTATCGCGCTGTCACCCCCGCTTATCATCACCAAGGGGCAGATTGA
CGAGATCGTGGACCATGTAAGGGAAATTTTGCGATCTATAGATTAA

Upstream 100 bases:

>100_bases
GGCGGTGTTAACGATTGTCCAAACGGTCAAAAATTGCGTATCGTTTTCCGGGGAGTACCAAGCTTGACCAGGACAAAAAG
AGGTAGAAGGAGGCTTGGTA

Downstream 100 bases:

>100_bases
GCGCCGGCCCTTCGGGGCTGGCCTGCATGTGAGCCGGAACGAAAGCCCAGAAAAGACGAGGGGAACCAAATGGCAGCACC
CGGCGAAAATCTGAGGATCA

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MLERPKRPNDLSAFWMPFTANRQFKQAPRMLVSAKDMHYTTDDGRKLLDGTAGLWCVNAGHCRPKITEAIRHQAGELDYA
PAFQMGHPIVFEFASRLVDIAPEGMDHVFFTNSGSESVETALKIALAYHRAKGDGSRTRLIGRERGYHGVNFGGISVGGI
VNNRKMFGTLLAGVDHLPHTYLPGKNAFSRGVPEHGVELADELERIVALHDASTIAAVIVEPVAGSAGVILPPKGYLKRL
REICDKHGILLIFDEVITGFGRLGTPFAADYFGVVPDIMTTAKGITNGVIPMGAVFVKKEIHDAFMNGPEHMIEFFHGYT
YSGNPIACAAGLATLETYREEGLLTRGEELGQHWEDALHSLKGEPHVIDIRNIGLVGAIEMEPIQGQPTKRAFSAFLKGF
EKGLLIRTTGDIIALSPPLIITKGQIDEIVDHVREILRSID

Sequences:

>Translated_441_residues
MLERPKRPNDLSAFWMPFTANRQFKQAPRMLVSAKDMHYTTDDGRKLLDGTAGLWCVNAGHCRPKITEAIRHQAGELDYA
PAFQMGHPIVFEFASRLVDIAPEGMDHVFFTNSGSESVETALKIALAYHRAKGDGSRTRLIGRERGYHGVNFGGISVGGI
VNNRKMFGTLLAGVDHLPHTYLPGKNAFSRGVPEHGVELADELERIVALHDASTIAAVIVEPVAGSAGVILPPKGYLKRL
REICDKHGILLIFDEVITGFGRLGTPFAADYFGVVPDIMTTAKGITNGVIPMGAVFVKKEIHDAFMNGPEHMIEFFHGYT
YSGNPIACAAGLATLETYREEGLLTRGEELGQHWEDALHSLKGEPHVIDIRNIGLVGAIEMEPIQGQPTKRAFSAFLKGF
EKGLLIRTTGDIIALSPPLIITKGQIDEIVDHVREILRSID
>Mature_441_residues
MLERPKRPNDLSAFWMPFTANRQFKQAPRMLVSAKDMHYTTDDGRKLLDGTAGLWCVNAGHCRPKITEAIRHQAGELDYA
PAFQMGHPIVFEFASRLVDIAPEGMDHVFFTNSGSESVETALKIALAYHRAKGDGSRTRLIGRERGYHGVNFGGISVGGI
VNNRKMFGTLLAGVDHLPHTYLPGKNAFSRGVPEHGVELADELERIVALHDASTIAAVIVEPVAGSAGVILPPKGYLKRL
REICDKHGILLIFDEVITGFGRLGTPFAADYFGVVPDIMTTAKGITNGVIPMGAVFVKKEIHDAFMNGPEHMIEFFHGYT
YSGNPIACAAGLATLETYREEGLLTRGEELGQHWEDALHSLKGEPHVIDIRNIGLVGAIEMEPIQGQPTKRAFSAFLKGF
EKGLLIRTTGDIIALSPPLIITKGQIDEIVDHVREILRSID

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=416, Percent_Identity=30.5288461538462, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI13994255, Length=442, Percent_Identity=29.8642533936652, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI37574042, Length=435, Percent_Identity=30.1149425287356, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI284507298, Length=331, Percent_Identity=31.7220543806647, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI226442709, Length=395, Percent_Identity=30.8860759493671, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI226442705, Length=431, Percent_Identity=29.4663573085847, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI24119277, Length=431, Percent_Identity=27.3781902552204, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI145693181, Length=405, Percent_Identity=31.8518518518519, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1786991, Length=437, Percent_Identity=31.5789473684211, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1789759, Length=395, Percent_Identity=31.3924050632911, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI1789016, Length=402, Percent_Identity=31.592039800995, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1787560, Length=417, Percent_Identity=30.4556354916067, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1788044, Length=410, Percent_Identity=27.3170731707317, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1786349, Length=341, Percent_Identity=30.2052785923754, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI32564660, Length=437, Percent_Identity=31.5789473684211, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI25144271, Length=416, Percent_Identity=29.5673076923077, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71992977, Length=436, Percent_Identity=29.8165137614679, Blast_Score=149, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI25144274, Length=228, Percent_Identity=36.4035087719298, Blast_Score=128, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6323470, Length=438, Percent_Identity=29.9086757990868, Blast_Score=184, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6324386, Length=481, Percent_Identity=26.4033264033264, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6324432, Length=415, Percent_Identity=29.1566265060241, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321456, Length=290, Percent_Identity=26.2068965517241, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357415, Length=405, Percent_Identity=29.8765432098765, Blast_Score=171, Evalue=9e-43,
Organism=Drosophila melanogaster, GI161085790, Length=439, Percent_Identity=29.3849658314351, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI28574759, Length=432, Percent_Identity=30.3240740740741, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21356575, Length=439, Percent_Identity=28.4738041002278, Blast_Score=137, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 48290; Mature: 48290

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLERPKRPNDLSAFWMPFTANRQFKQAPRMLVSAKDMHYTTDDGRKLLDGTAGLWCVNAG
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHCCCCCEEEECCC
HCRPKITEAIRHQAGELDYAPAFQMGHPIVFEFASRLVDIAPEGMDHVFFTNSGSESVET
CCCHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHH
ALKIALAYHRAKGDGSRTRLIGRERGYHGVNFGGISVGGIVNNRKMFGTLLAGVDHLPHT
HHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCCCEEECCEECCHHHHHHHHHHHHHCCCC
YLPGKNAFSRGVPEHGVELADELERIVALHDASTIAAVIVEPVAGSAGVILPPKGYLKRL
CCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCHHHEEHHHHHCCCCCCCEEECCHHHHHHH
REICDKHGILLIFDEVITGFGRLGTPFAADYFGVVPDIMTTAKGITNGVIPMGAVFVKKE
HHHHHHCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
IHDAFMNGPEHMIEFFHGYTYSGNPIACAAGLATLETYREEGLLTRGEELGQHWEDALHS
HHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LKGEPHVIDIRNIGLVGAIEMEPIQGQPTKRAFSAFLKGFEKGLLIRTTGDIIALSPPLI
CCCCCCEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECCCEEEECCCEE
ITKGQIDEIVDHVREILRSID
EECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLERPKRPNDLSAFWMPFTANRQFKQAPRMLVSAKDMHYTTDDGRKLLDGTAGLWCVNAG
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHCCCCCEEEECCC
HCRPKITEAIRHQAGELDYAPAFQMGHPIVFEFASRLVDIAPEGMDHVFFTNSGSESVET
CCCHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHH
ALKIALAYHRAKGDGSRTRLIGRERGYHGVNFGGISVGGIVNNRKMFGTLLAGVDHLPHT
HHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCCCEEECCEECCHHHHHHHHHHHHHCCCC
YLPGKNAFSRGVPEHGVELADELERIVALHDASTIAAVIVEPVAGSAGVILPPKGYLKRL
CCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCHHHEEHHHHHCCCCCCCEEECCHHHHHHH
REICDKHGILLIFDEVITGFGRLGTPFAADYFGVVPDIMTTAKGITNGVIPMGAVFVKKE
HHHHHHCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
IHDAFMNGPEHMIEFFHGYTYSGNPIACAAGLATLETYREEGLLTRGEELGQHWEDALHS
HHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LKGEPHVIDIRNIGLVGAIEMEPIQGQPTKRAFSAFLKGFEKGLLIRTTGDIIALSPPLI
CCCCCCEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECCCEEEECCCEE
ITKGQIDEIVDHVREILRSID
EECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]