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The map label for this gene is potH [H]

Identifier: 110634287

GI number: 110634287

Start: 2074453

End: 2076273

Strand: Reverse

Name: potH [H]

Synonym: Meso_1937

Alternate gene names: 110634287

Gene position: 2076273-2074453 (Counterclockwise)

Preceding gene: 110634288

Following gene: 110634286

Centisome position: 47.05

GC content: 55.85

Gene sequence:

>1821_bases
ATGAGCGTTGCTCGCTCGCAGGGGGGGCTAGTTGCAGGAGTGGGGCGTGGCGAACAGTTGAACCTACGTTCATTTCGCAA
TCGCCCGGCCCTCTCTCTGCTTCCGCTTGTTCCCGCCTGGGTATTTCTGCTCCTCTTCTTTGCGCTGCCGCTGATCTTCG
TTACCGGCGCCAGCATCTTCGATGAGAGTGGAGCGCTTTCGCTGCAGAACTTTGTCCGGCTTGTGGAAACGCCGGTCTAT
TGGCGCATTCTCCTCAACACTCTGGACATTGCGTTCTGGACGGCCTGTATCACGGTCGTAGTCGGTTATCCGCTGGCGCG
CATGCTGGCTTCCGGGGAGCGCAGTGGCACCAGTTTTTTGATGATCGCCATCATGGTTCCGCTCTGGACCAGCTTTCTCG
TTCGCGCGCTGGCCTGGATGCTGGTCTTGTCCAGATATGGTGTCATCAACAGCACGATGCTGTCTCTCGGTTTGCTCGAT
ACGCCGGCGCGGCTGGTTAATAATTACCCAGCGGTGCTGCTGGCGATGGTGCACGGCATGCTGCCCCTGGCCGTGCTGAC
GATGTATTCGGTTATGCAGAACATCGACCCGGCCCTGTCTCGGGCAGCTTCGACGCTTGGTGCCCGCTCTGGCAATGCGT
TCTGGCGAGTCTACTTCCCTCTGTCGCTGCCAGGGGTGGCTTCAGCTTGGCTCGTCGTCTTCGTTTCTGCACTCGGAACC
TTCATCGTGCCGGTCCTGCTTGGTAGTCCGCGTGAAATGATGATCGCCGGCTCCATCGTCGAGCAGATCAACAATAACTT
TAATTGGGGCTTTGCGGGCGCCCTGACAGTGATGCTGTTAGGGGCAACCCTCCTCGTTTATCTCGTTTTTGAAAGAACCC
TAGGTAGCTCAGTTTTATCAGGCGGCGCCGTGAGTGCGGCAACGGGCAGCGGTCGCAGTGGACGCATCCAGCAAAGGATC
AGGCCGCTTGGTGGTCGTATTCTCGCCTTTGTTGGCGCAGTGACGGTCCATTTCGAGAAGATCCTCGATTCGATATTGGG
TCAGCGACAGGCCGGAAGCGGCTTACTCCTGAAAATCACGGCCTGGCTGCTGGTCGCCTTCCTGATCCTGCCAGTCGTCT
TCGTGATCCCGGTTTCTTTCTCGGAAGATCGCTTCTTCAGTTGGCCGCCAGTCGGATTCACGACGGAATGGTTTGCAACG
TATTTCACCTCGACGGTGTGGATGCAAGCAACTCTCAATTCCGTGCTGTTCGCTTTTGTCTCGGCTATCGCATCGATGGT
GATTGGTATTCCTGCCGCGTTGGTGCTGGCACGTAGAAGCGTACCAATGCGGGCGCTGCTGATGATGCTGGTTCTGATGC
CGATCGTGCTGCCGAATGTTATCGTGGCAGTCGGGCTGTTCTATATCTTTGCCTATGTAAACATGGTGGGAACCATTTGG
GCGATCATCATCGGCCATACAGTTCTCAATCTTCCCTATGTGATCATCACTGTCATGGCGGTGCTCAAGAACTATGACGT
CCGTCTAGATCACGCCAGCTGGACCCTCGGCGCTGGAAAGCTGCAAACCTTCCGCTTGGTGACGATGCCAATCTTGAGAG
CAGGCATCACAGCAGCGTTCCTCTTTGCCTTCGTACGCTCCTTTGACGATCTCTCGATTGTTCTCTTTCTCGGAGCAGGA
CAGCTTAGCACGCTACCTTTGCAGCTATGGTCTACTGCCCTGGTCGGTATTGATTCAACCCTCGCGGCAGTATCGACGGT
CATTTTCGGGGCTGTTTGCATTGTAGTGATTGTGGCAATCCGCATCGGATCAAAAAAATAG

Upstream 100 bases:

>100_bases
AGGGCATTGTTGACAAAGACCGAGATGAGTTTTTGCTTATCAGGAAGGAGCAGGGGCTCAAGGCAGCCGTCGCCTGGCGT
GCCCAGCGGGTTGGTGCGCA

Downstream 100 bases:

>100_bases
CCTGAACGGCTAATATGGTTTCTTTAGTGTGGAGGAGAAAACATGAAGACGATTGAACTATCACGAAGGAATGCTTTGAA
GGTGATCGCAGGATCGAGTG

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; putrescine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 606; Mature: 605

Protein sequence:

>606_residues
MSVARSQGGLVAGVGRGEQLNLRSFRNRPALSLLPLVPAWVFLLLFFALPLIFVTGASIFDESGALSLQNFVRLVETPVY
WRILLNTLDIAFWTACITVVVGYPLARMLASGERSGTSFLMIAIMVPLWTSFLVRALAWMLVLSRYGVINSTMLSLGLLD
TPARLVNNYPAVLLAMVHGMLPLAVLTMYSVMQNIDPALSRAASTLGARSGNAFWRVYFPLSLPGVASAWLVVFVSALGT
FIVPVLLGSPREMMIAGSIVEQINNNFNWGFAGALTVMLLGATLLVYLVFERTLGSSVLSGGAVSAATGSGRSGRIQQRI
RPLGGRILAFVGAVTVHFEKILDSILGQRQAGSGLLLKITAWLLVAFLILPVVFVIPVSFSEDRFFSWPPVGFTTEWFAT
YFTSTVWMQATLNSVLFAFVSAIASMVIGIPAALVLARRSVPMRALLMMLVLMPIVLPNVIVAVGLFYIFAYVNMVGTIW
AIIIGHTVLNLPYVIITVMAVLKNYDVRLDHASWTLGAGKLQTFRLVTMPILRAGITAAFLFAFVRSFDDLSIVLFLGAG
QLSTLPLQLWSTALVGIDSTLAAVSTVIFGAVCIVVIVAIRIGSKK

Sequences:

>Translated_606_residues
MSVARSQGGLVAGVGRGEQLNLRSFRNRPALSLLPLVPAWVFLLLFFALPLIFVTGASIFDESGALSLQNFVRLVETPVY
WRILLNTLDIAFWTACITVVVGYPLARMLASGERSGTSFLMIAIMVPLWTSFLVRALAWMLVLSRYGVINSTMLSLGLLD
TPARLVNNYPAVLLAMVHGMLPLAVLTMYSVMQNIDPALSRAASTLGARSGNAFWRVYFPLSLPGVASAWLVVFVSALGT
FIVPVLLGSPREMMIAGSIVEQINNNFNWGFAGALTVMLLGATLLVYLVFERTLGSSVLSGGAVSAATGSGRSGRIQQRI
RPLGGRILAFVGAVTVHFEKILDSILGQRQAGSGLLLKITAWLLVAFLILPVVFVIPVSFSEDRFFSWPPVGFTTEWFAT
YFTSTVWMQATLNSVLFAFVSAIASMVIGIPAALVLARRSVPMRALLMMLVLMPIVLPNVIVAVGLFYIFAYVNMVGTIW
AIIIGHTVLNLPYVIITVMAVLKNYDVRLDHASWTLGAGKLQTFRLVTMPILRAGITAAFLFAFVRSFDDLSIVLFLGAG
QLSTLPLQLWSTALVGIDSTLAAVSTVIFGAVCIVVIVAIRIGSKK
>Mature_605_residues
SVARSQGGLVAGVGRGEQLNLRSFRNRPALSLLPLVPAWVFLLLFFALPLIFVTGASIFDESGALSLQNFVRLVETPVYW
RILLNTLDIAFWTACITVVVGYPLARMLASGERSGTSFLMIAIMVPLWTSFLVRALAWMLVLSRYGVINSTMLSLGLLDT
PARLVNNYPAVLLAMVHGMLPLAVLTMYSVMQNIDPALSRAASTLGARSGNAFWRVYFPLSLPGVASAWLVVFVSALGTF
IVPVLLGSPREMMIAGSIVEQINNNFNWGFAGALTVMLLGATLLVYLVFERTLGSSVLSGGAVSAATGSGRSGRIQQRIR
PLGGRILAFVGAVTVHFEKILDSILGQRQAGSGLLLKITAWLLVAFLILPVVFVIPVSFSEDRFFSWPPVGFTTEWFATY
FTSTVWMQATLNSVLFAFVSAIASMVIGIPAALVLARRSVPMRALLMMLVLMPIVLPNVIVAVGLFYIFAYVNMVGTIWA
IIIGHTVLNLPYVIITVMAVLKNYDVRLDHASWTLGAGKLQTFRLVTMPILRAGITAAFLFAFVRSFDDLSIVLFLGAGQ
LSTLPLQLWSTALVGIDSTLAAVSTVIFGAVCIVVIVAIRIGSKK

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine [H]

COG id: COG1176

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787080, Length=237, Percent_Identity=33.7552742616034, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1787369, Length=265, Percent_Identity=33.2075471698113, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1787368, Length=232, Percent_Identity=28.0172413793103, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1787713, Length=276, Percent_Identity=29.7101449275362, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787714, Length=214, Percent_Identity=33.1775700934579, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787081, Length=245, Percent_Identity=28.9795918367347, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788764, Length=162, Percent_Identity=29.0123456790123, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 65549; Mature: 65418

Theoretical pI: Translated: 10.84; Mature: 10.84

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVARSQGGLVAGVGRGEQLNLRSFRNRPALSLLPLVPAWVFLLLFFALPLIFVTGASIF
CCCCCCCCCEEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DESGALSLQNFVRLVETPVYWRILLNTLDIAFWTACITVVVGYPLARMLASGERSGTSFL
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
MIAIMVPLWTSFLVRALAWMLVLSRYGVINSTMLSLGLLDTPARLVNNYPAVLLAMVHGM
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
LPLAVLTMYSVMQNIDPALSRAASTLGARSGNAFWRVYFPLSLPGVASAWLVVFVSALGT
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
FIVPVLLGSPREMMIAGSIVEQINNNFNWGFAGALTVMLLGATLLVYLVFERTLGSSVLS
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGAVSAATGSGRSGRIQQRIRPLGGRILAFVGAVTVHFEKILDSILGQRQAGSGLLLKIT
CCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AWLLVAFLILPVVFVIPVSFSEDRFFSWPPVGFTTEWFATYFTSTVWMQATLNSVLFAFV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SAIASMVIGIPAALVLARRSVPMRALLMMLVLMPIVLPNVIVAVGLFYIFAYVNMVGTIW
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIIIGHTVLNLPYVIITVMAVLKNYDVRLDHASWTLGAGKLQTFRLVTMPILRAGITAAF
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHH
LFAFVRSFDDLSIVLFLGAGQLSTLPLQLWSTALVGIDSTLAAVSTVIFGAVCIVVIVAI
HHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
RIGSKK
HHCCCC
>Mature Secondary Structure 
SVARSQGGLVAGVGRGEQLNLRSFRNRPALSLLPLVPAWVFLLLFFALPLIFVTGASIF
CCCCCCCCEEEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DESGALSLQNFVRLVETPVYWRILLNTLDIAFWTACITVVVGYPLARMLASGERSGTSFL
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
MIAIMVPLWTSFLVRALAWMLVLSRYGVINSTMLSLGLLDTPARLVNNYPAVLLAMVHGM
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
LPLAVLTMYSVMQNIDPALSRAASTLGARSGNAFWRVYFPLSLPGVASAWLVVFVSALGT
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
FIVPVLLGSPREMMIAGSIVEQINNNFNWGFAGALTVMLLGATLLVYLVFERTLGSSVLS
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGAVSAATGSGRSGRIQQRIRPLGGRILAFVGAVTVHFEKILDSILGQRQAGSGLLLKIT
CCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AWLLVAFLILPVVFVIPVSFSEDRFFSWPPVGFTTEWFATYFTSTVWMQATLNSVLFAFV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SAIASMVIGIPAALVLARRSVPMRALLMMLVLMPIVLPNVIVAVGLFYIFAYVNMVGTIW
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIIIGHTVLNLPYVIITVMAVLKNYDVRLDHASWTLGAGKLQTFRLVTMPILRAGITAAF
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHH
LFAFVRSFDDLSIVLFLGAGQLSTLPLQLWSTALVGIDSTLAAVSTVIFGAVCIVVIVAI
HHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
RIGSKK
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; putrescine [Periplasm]; H2O [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8416922; 8905232; 9278503 [H]