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The map label for this gene is exuR [H]

Identifier: 110634279

GI number: 110634279

Start: 2065664

End: 2066707

Strand: Reverse

Name: exuR [H]

Synonym: Meso_1929

Alternate gene names: 110634279

Gene position: 2066707-2065664 (Counterclockwise)

Preceding gene: 110634280

Following gene: 110634278

Centisome position: 46.84

GC content: 55.08

Gene sequence:

>1044_bases
GTGTCTGACGCGGTGAATAGTTCACAACCTAGTGCAAAGACGCCTGTCACCGCGCGGGATGTCGCCCGCAACGCGGGTGT
CTCACAGTCAACCGTTTCACGCGCCTTCGCCAACAGCCAATTGGTCTCGAGAGAAACTCGGGACCGGATATTCTTGGTTG
CCGAACAGCTTGGTTACCAGGTCAATATCATGGCACGCGGTCTGAGCACGCAAAAATCGGGGCTCATCGCTGTTGTCACG
GGATCAACCCGCAACCCCTTCTATTGGGACGTGCTTCGTTTGGTTGACGAACGCCTGCAGGCCAAGGGCATGCACGTCAT
GCTCATGACAGTAAAGGAGAGCGAGAGCACCGATTCGGCAGTGCGGAAAGTCCATCAGTATCGAGTCGACGGCCTGCTTG
TCCTATCGGCGGAACTGTCATCGAAGGCGATTGACGAATGCAGAGAGTTCGGGCTGCCGGTAGTTCTGTTCAATCGCTAT
GTCGAAACGGGCAAAGTCTCTGCCGTGGCCTGTGATAACATCGTCGCTGGGAAGGACATCGCCCAGTTTCTCTACAACAC
GAATCACAAGCGGTTCGCGTTCATCTCTGGTTTGGAAGACAGTTCGACAAACAAGGACCGCTTTCAGGGATATCGGGATC
AACTGGCAAAGCTTGGATGTCCGCCTCCGCTCGTCGAAGGAGGAGATTTTACATACGAGAACGGCCGGCAGGCGGTGAAA
AGGCTGATGCTTCGATCCGAACGGCCAGATGCAATCTTCTGCGCTAATGACATCACAGCTATCGGTGCATTGGACGGCAT
AAGGGTGGATCTTGGGATGAGGGTGCCAGAGGATGTTTCGATTATTGGCTTTGACGATATTGCGATGTCCTCGTGGTCCG
GCATTGAACTGACTACCATGCGCCAGCAGACAACGCGGATGGTGGATAGTGCGCTGGAGATTTTGCTCCGGAGGATTGAT
GCCCCAGAACTGAAGCCGGAATTTCGGTTGGAGCCCGGAAAGCTAATGATCCGCCGAACCGTGCGGTTGGATCGGCAGCC
CTAG

Upstream 100 bases:

>100_bases
TCTGCCGAGTCGCGCAACCATCGGTGTTGCCGATCTGGGAGAAGGCGTGCTCGTAGAAGCGGTCGTGACAGCCCGCCAAT
GAGGTTGAACGAGGTAAACT

Downstream 100 bases:

>100_bases
CCCGACCAGGGCGCGGGAAGAACCACAATTAGCTAGTCACAAGGAGACGACAGCCGGAGTAGGGCTTCGTCCCAGGGAGA
AAGTCATGCCTAAATACTTG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Probable galacturonate locus repressor [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSDAVNSSQPSAKTPVTARDVARNAGVSQSTVSRAFANSQLVSRETRDRIFLVAEQLGYQVNIMARGLSTQKSGLIAVVT
GSTRNPFYWDVLRLVDERLQAKGMHVMLMTVKESESTDSAVRKVHQYRVDGLLVLSAELSSKAIDECREFGLPVVLFNRY
VETGKVSAVACDNIVAGKDIAQFLYNTNHKRFAFISGLEDSSTNKDRFQGYRDQLAKLGCPPPLVEGGDFTYENGRQAVK
RLMLRSERPDAIFCANDITAIGALDGIRVDLGMRVPEDVSIIGFDDIAMSSWSGIELTTMRQQTTRMVDSALEILLRRID
APELKPEFRLEPGKLMIRRTVRLDRQP

Sequences:

>Translated_347_residues
MSDAVNSSQPSAKTPVTARDVARNAGVSQSTVSRAFANSQLVSRETRDRIFLVAEQLGYQVNIMARGLSTQKSGLIAVVT
GSTRNPFYWDVLRLVDERLQAKGMHVMLMTVKESESTDSAVRKVHQYRVDGLLVLSAELSSKAIDECREFGLPVVLFNRY
VETGKVSAVACDNIVAGKDIAQFLYNTNHKRFAFISGLEDSSTNKDRFQGYRDQLAKLGCPPPLVEGGDFTYENGRQAVK
RLMLRSERPDAIFCANDITAIGALDGIRVDLGMRVPEDVSIIGFDDIAMSSWSGIELTTMRQQTTRMVDSALEILLRRID
APELKPEFRLEPGKLMIRRTVRLDRQP
>Mature_346_residues
SDAVNSSQPSAKTPVTARDVARNAGVSQSTVSRAFANSQLVSRETRDRIFLVAEQLGYQVNIMARGLSTQKSGLIAVVTG
STRNPFYWDVLRLVDERLQAKGMHVMLMTVKESESTDSAVRKVHQYRVDGLLVLSAELSSKAIDECREFGLPVVLFNRYV
ETGKVSAVACDNIVAGKDIAQFLYNTNHKRFAFISGLEDSSTNKDRFQGYRDQLAKLGCPPPLVEGGDFTYENGRQAVKR
LMLRSERPDAIFCANDITAIGALDGIRVDLGMRVPEDVSIIGFDDIAMSSWSGIELTTMRQQTTRMVDSALEILLRRIDA
PELKPEFRLEPGKLMIRRTVRLDRQP

Specific function: Transcriptional repressor for the exu locus which is required for galacturonate utilization (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=334, Percent_Identity=31.7365269461078, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1789068, Length=331, Percent_Identity=33.2326283987915, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1790194, Length=328, Percent_Identity=30.1829268292683, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787948, Length=331, Percent_Identity=28.0966767371601, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788474, Length=311, Percent_Identity=33.1189710610932, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789202, Length=294, Percent_Identity=29.5918367346939, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1787580, Length=310, Percent_Identity=26.1290322580645, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1786540, Length=329, Percent_Identity=27.355623100304, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787906, Length=259, Percent_Identity=29.3436293436293, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI48994940, Length=331, Percent_Identity=27.7945619335347, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789456, Length=340, Percent_Identity=25.5882352941176, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790715, Length=275, Percent_Identity=24, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38611; Mature: 38479

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAVNSSQPSAKTPVTARDVARNAGVSQSTVSRAFANSQLVSRETRDRIFLVAEQLGYQ
CCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHCCE
VNIMARGLSTQKSGLIAVVTGSTRNPFYWDVLRLVDERLQAKGMHVMLMTVKESESTDSA
EEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHH
VRKVHQYRVDGLLVLSAELSSKAIDECREFGLPVVLFNRYVETGKVSAVACDNIVAGKDI
HHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCEEEHHHHHHCCCEEEEECCCCCCHHHH
AQFLYNTNHKRFAFISGLEDSSTNKDRFQGYRDQLAKLGCPPPLVEGGDFTYENGRQAVK
HHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
RLMLRSERPDAIFCANDITAIGALDGIRVDLGMRVPEDVSIIGFDDIAMSSWSGIELTTM
HHHHHCCCCCEEEEECCCHHHHCCCCEEEEECCCCCCCCEEEEECHHHHCCCCCEEEEHH
RQQTTRMVDSALEILLRRIDAPELKPEFRLEPGKLMIRRTVRLDRQP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SDAVNSSQPSAKTPVTARDVARNAGVSQSTVSRAFANSQLVSRETRDRIFLVAEQLGYQ
CCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHCCE
VNIMARGLSTQKSGLIAVVTGSTRNPFYWDVLRLVDERLQAKGMHVMLMTVKESESTDSA
EEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHH
VRKVHQYRVDGLLVLSAELSSKAIDECREFGLPVVLFNRYVETGKVSAVACDNIVAGKDI
HHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCEEEHHHHHHCCCEEEEECCCCCCHHHH
AQFLYNTNHKRFAFISGLEDSSTNKDRFQGYRDQLAKLGCPPPLVEGGDFTYENGRQAVK
HHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
RLMLRSERPDAIFCANDITAIGALDGIRVDLGMRVPEDVSIIGFDDIAMSSWSGIELTTM
HHHHHCCCCCEEEEECCCHHHHCCCCEEEEECCCCCCCCEEEEECHHHHCCCCCEEEEHH
RQQTTRMVDSALEILLRRIDAPELKPEFRLEPGKLMIRRTVRLDRQP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]