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The map label for this gene is glpR [H]

Identifier: 110633942

GI number: 110633942

Start: 1712296

End: 1713066

Strand: Direct

Name: glpR [H]

Synonym: Meso_1590

Alternate gene names: 110633942

Gene position: 1712296-1713066 (Clockwise)

Preceding gene: 110633941

Following gene: 110633943

Centisome position: 38.81

GC content: 58.11

Gene sequence:

>771_bases
ATGTTTCTGCCGCCCCGCCATGCGGAAATAGTCCAGCTCGCCAAGGATAGCGGGAGGGTGCTTGTCGACGATCTGGCTGC
CCGGTTCAATGTCACGCCGCAGACGATCCGCAAGGATTTGAACGATCTCTGCGATCAAAGGCTTTTGACCCGCATCCATG
GCGGGGCTGTCTTCCCGTCCGGCATCGAGAATATGGAATATGAAGCGCGGCGCAAGATCTCGGCCGGCGAGAAGGAGGCT
ATAGGCCAGGCTGCTGCCCGCATCATCCCCGATAACGCATCGCTATTCATGAATATCGGCACGACGACGGAAGCCGTAGG
CCACGCTCTTCTCGACCATCAAGGGCTGCTGGTCATCACGAACAATATTAATGTCGCCAACAGGTTGCGGGTGCTCCCGT
CGATCGAGGTAATCATTGCCGGCGGGGTCGTGCGCTCGTCGGATGGAGGCATTGTCGGCGAGGCGGCAGTCGACTTCATC
AAGCAGTTCAAAGTGGATTATGCCGTGATCGGCACGTCTGCGATCGACCATGACGGCGCCCTGCTCGATTTCGATTTTCG
TGAAGTGAAGGTGGCTCAGGCCATTATCGCCAACGCGCGGCATGTGATCCTCGTGGCAGACTCGACCAAATTCGAGCGGA
CCGCCCCTGTGCGGATCGGCCATCTCTCACAGGTCGACACGTTCATTACCAATCGCTGCAAGTTGGAAGCGATACGCGCA
ATCTGTCAGGCGGCGGAGGTCGAGCTGATCGAAACTGCCCGTGCAAATTGA

Upstream 100 bases:

>100_bases
CTTTGAAGCCTCGCGCGCAACGCTTCAAAATTCCTTCCAAATCCAGTTTCGTTTCTTTCGTTTTTCTGTATATTGGGGCA
AAACGAAATTGGGGGAATCC

Downstream 100 bases:

>100_bases
AGGCGAGAAACTCGCTTCCATTTTCGTTTGACACTCGCAATAATTTCGAATTAACTCGTTTTTGCTTTCGTATTACACGA
CGCCTTCAGTGGCGCGCGGG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MFLPPRHAEIVQLAKDSGRVLVDDLAARFNVTPQTIRKDLNDLCDQRLLTRIHGGAVFPSGIENMEYEARRKISAGEKEA
IGQAAARIIPDNASLFMNIGTTTEAVGHALLDHQGLLVITNNINVANRLRVLPSIEVIIAGGVVRSSDGGIVGEAAVDFI
KQFKVDYAVIGTSAIDHDGALLDFDFREVKVAQAIIANARHVILVADSTKFERTAPVRIGHLSQVDTFITNRCKLEAIRA
ICQAAEVELIETARAN

Sequences:

>Translated_256_residues
MFLPPRHAEIVQLAKDSGRVLVDDLAARFNVTPQTIRKDLNDLCDQRLLTRIHGGAVFPSGIENMEYEARRKISAGEKEA
IGQAAARIIPDNASLFMNIGTTTEAVGHALLDHQGLLVITNNINVANRLRVLPSIEVIIAGGVVRSSDGGIVGEAAVDFI
KQFKVDYAVIGTSAIDHDGALLDFDFREVKVAQAIIANARHVILVADSTKFERTAPVRIGHLSQVDTFITNRCKLEAIRA
ICQAAEVELIETARAN
>Mature_256_residues
MFLPPRHAEIVQLAKDSGRVLVDDLAARFNVTPQTIRKDLNDLCDQRLLTRIHGGAVFPSGIENMEYEARRKISAGEKEA
IGQAAARIIPDNASLFMNIGTTTEAVGHALLDHQGLLVITNNINVANRLRVLPSIEVIIAGGVVRSSDGGIVGEAAVDFI
KQFKVDYAVIGTSAIDHDGALLDFDFREVKVAQAIIANARHVILVADSTKFERTAPVRIGHLSQVDTFITNRCKLEAIRA
ICQAAEVELIETARAN

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=226, Percent_Identity=49.5575221238938, Blast_Score=236, Evalue=1e-63,
Organism=Escherichia coli, GI87082344, Length=246, Percent_Identity=40.2439024390244, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI1789059, Length=252, Percent_Identity=29.7619047619048, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788069, Length=254, Percent_Identity=27.9527559055118, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI226510968, Length=227, Percent_Identity=29.0748898678414, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789519, Length=229, Percent_Identity=27.5109170305677, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790753, Length=223, Percent_Identity=29.5964125560538, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1789170, Length=230, Percent_Identity=25.6521739130435, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787540, Length=230, Percent_Identity=26.9565217391304, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787063, Length=250, Percent_Identity=22.8, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27795; Mature: 27795

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLPPRHAEIVQLAKDSGRVLVDDLAARFNVTPQTIRKDLNDLCDQRLLTRIHGGAVFPS
CCCCCCHHHHHHHHHCCCCEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GIENMEYEARRKISAGEKEAIGQAAARIIPDNASLFMNIGTTTEAVGHALLDHQGLLVIT
CCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEE
NNINVANRLRVLPSIEVIIAGGVVRSSDGGIVGEAAVDFIKQFKVDYAVIGTSAIDHDGA
CCCCHHHHHHHCCCEEEEEECCEEECCCCCEEHHHHHHHHHHHCCCEEEEECCEECCCCC
LLDFDFREVKVAQAIIANARHVILVADSTKFERTAPVRIGHLSQVDTFITNRCKLEAIRA
EEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
ICQAAEVELIETARAN
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFLPPRHAEIVQLAKDSGRVLVDDLAARFNVTPQTIRKDLNDLCDQRLLTRIHGGAVFPS
CCCCCCHHHHHHHHHCCCCEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GIENMEYEARRKISAGEKEAIGQAAARIIPDNASLFMNIGTTTEAVGHALLDHQGLLVIT
CCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEE
NNINVANRLRVLPSIEVIIAGGVVRSSDGGIVGEAAVDFIKQFKVDYAVIGTSAIDHDGA
CCCCHHHHHHHCCCEEEEEECCEEECCCCCEEHHHHHHHHHHHCCCEEEEECCEECCCCC
LLDFDFREVKVAQAIIANARHVILVADSTKFERTAPVRIGHLSQVDTFITNRCKLEAIRA
EEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
ICQAAEVELIETARAN
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]