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The map label for this gene is glpD [H]

Identifier: 110633943

GI number: 110633943

Start: 1713176

End: 1714705

Strand: Direct

Name: glpD [H]

Synonym: Meso_1591

Alternate gene names: 110633943

Gene position: 1713176-1714705 (Clockwise)

Preceding gene: 110633942

Following gene: 110633944

Centisome position: 38.83

GC content: 64.9

Gene sequence:

>1530_bases
TTGGACGGCACTCCGGTCCATGACATTCTTGTTATCGGCGGCGGCATCAATGGCTGCGGCATCGCGCGGGATGCAGCAGG
CCGGGGATACAGCGTCTTTCTCGCGGAAATGAACGACCTTGGAAGCGGCACGTCGTCCGGCTCCACCAAGCTCATCCATG
GCGGCCTGCGCTACCTCGAATTCTATGAGTTCCGGCTTGTGCGGGAGGCGCTGCTCGAGCGCGAGGTGCTGTGGCGCAAC
GCGCCGCACATTATCTGGCCGATGCGGTTCGTTCTGCCGCATAATGAGGGGCTGAGGCCAGCCTGGCTGCTGCGTCTCGG
CCTCTTCCTCTATGACCATCTCGGCGGGCGCAAGCTCCTTCCCAAGACGCGTACGATCGATATGCGCATCGATGCTGCCG
GCAAGCCGCTCAAGCCGCTCTTTTCCCGCGCCTTCGAATATTCCGATTGCTGGGTCGACGACGCCCGCTTGGTGGTGCTC
AACGCGCGGGACGCGGCCGACCGGGGCGCGGTGATCGCCACCCGCACCGAGGTGGTCGACGCGCGCCGGGAGGATGGCCG
ATGGCGGGCAACGCTGCGCGATGTCTCGAGCGGCGCGCGGTCCGAGGTTCGGGCGCGCCTTGTCGTGAACGCCGCCGGCC
CCTGGGTGGACAAGGTGCTGGCCTCCGCGATGGGGCGGAACGAAGTGCATAATGTGCGGCTGGTCAAAGGCAGCCATATC
GTGGTGCCGAAGGTTTCAGACGATCCACGCGCCTATTTCTTTCAGAACCGCGACGGCCGCATCATTTTCGCAATCCCATA
TGAGGACGATTTCACGCTGATCGGCACGACCGATCAGGATTATGACGGCGAGCCGCGGGACGCGGCGATCAGCCCTGCCG
AGACCGACTATCTCTGTGCGGCGGCGAGCGAGTATTTCGCCAGGCCGGTACGTCGGGAAGATATCGTTTGGACCTATGCC
GCCGTCCGCCCGCTCTTCGACGACGGCGCCTCCAAGGCGCAGGAAGCCACCCGCGATTACGTGCTGCGCGTGGAGGAGGG
GGACGGCGATGCCGCGCTCGTCAACATCTTCGGCGGCAAGATCACCACTTACCGGCGTCTTTCCGAAGCCACGCTGGAAA
AAATCGAAGAGTTGCTCGGCCGCAAAGGACAGGCCTGGACGGCCGATGCGCGGCTGCCGGGAGGAGATTTCGCGGTCGAC
GGTTTCGATGGGCAGATCGCAGGACTCCTGCGCGACTACCCGTTTCTCAATGCCGGTCACGCGCGCCGGCTGGTGCGCCG
CTATGGCACGCGGGCACGCGCAATTCTCGGGCAGGCGCGGTCGACCGACGATCTGGGGGTTCATTTCGGGGCTGACCTCT
ATGAGGCGGAGGTCCGGTATCTGATGGAGCAGGAGTGGGCACGCACGGCCGAGGACGTACTCTGGCGCCGCACGAAACGT
GGCCTGCGCCTTGCGCCGAATGAGGTCGTGACCCTGGAGGAATTCATGGAGGATCTCGCCAGCCGCAGACGGCACGAGGC
AGCCGAGTAG

Upstream 100 bases:

>100_bases
ACTCGCTTCCATTTTCGTTTGACACTCGCAATAATTTCGAATTAACTCGTTTTTGCTTTCGTATTACACGACGCCTTCAG
TGGCGCGCGGGGAGAAGAGC

Downstream 100 bases:

>100_bases
GAAAGATCAGAGAGGCCCCTGGGGAGGAGGCGCAATGCTCGAGCTCAAGAATGTCACGAAGAGGGTAGGGGCGGAGACGC
ATATCGAGGATGTGTCGCTG

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MDGTPVHDILVIGGGINGCGIARDAAGRGYSVFLAEMNDLGSGTSSGSTKLIHGGLRYLEFYEFRLVREALLEREVLWRN
APHIIWPMRFVLPHNEGLRPAWLLRLGLFLYDHLGGRKLLPKTRTIDMRIDAAGKPLKPLFSRAFEYSDCWVDDARLVVL
NARDAADRGAVIATRTEVVDARREDGRWRATLRDVSSGARSEVRARLVVNAAGPWVDKVLASAMGRNEVHNVRLVKGSHI
VVPKVSDDPRAYFFQNRDGRIIFAIPYEDDFTLIGTTDQDYDGEPRDAAISPAETDYLCAAASEYFARPVRREDIVWTYA
AVRPLFDDGASKAQEATRDYVLRVEEGDGDAALVNIFGGKITTYRRLSEATLEKIEELLGRKGQAWTADARLPGGDFAVD
GFDGQIAGLLRDYPFLNAGHARRLVRRYGTRARAILGQARSTDDLGVHFGADLYEAEVRYLMEQEWARTAEDVLWRRTKR
GLRLAPNEVVTLEEFMEDLASRRRHEAAE

Sequences:

>Translated_509_residues
MDGTPVHDILVIGGGINGCGIARDAAGRGYSVFLAEMNDLGSGTSSGSTKLIHGGLRYLEFYEFRLVREALLEREVLWRN
APHIIWPMRFVLPHNEGLRPAWLLRLGLFLYDHLGGRKLLPKTRTIDMRIDAAGKPLKPLFSRAFEYSDCWVDDARLVVL
NARDAADRGAVIATRTEVVDARREDGRWRATLRDVSSGARSEVRARLVVNAAGPWVDKVLASAMGRNEVHNVRLVKGSHI
VVPKVSDDPRAYFFQNRDGRIIFAIPYEDDFTLIGTTDQDYDGEPRDAAISPAETDYLCAAASEYFARPVRREDIVWTYA
AVRPLFDDGASKAQEATRDYVLRVEEGDGDAALVNIFGGKITTYRRLSEATLEKIEELLGRKGQAWTADARLPGGDFAVD
GFDGQIAGLLRDYPFLNAGHARRLVRRYGTRARAILGQARSTDDLGVHFGADLYEAEVRYLMEQEWARTAEDVLWRRTKR
GLRLAPNEVVTLEEFMEDLASRRRHEAAE
>Mature_509_residues
MDGTPVHDILVIGGGINGCGIARDAAGRGYSVFLAEMNDLGSGTSSGSTKLIHGGLRYLEFYEFRLVREALLEREVLWRN
APHIIWPMRFVLPHNEGLRPAWLLRLGLFLYDHLGGRKLLPKTRTIDMRIDAAGKPLKPLFSRAFEYSDCWVDDARLVVL
NARDAADRGAVIATRTEVVDARREDGRWRATLRDVSSGARSEVRARLVVNAAGPWVDKVLASAMGRNEVHNVRLVKGSHI
VVPKVSDDPRAYFFQNRDGRIIFAIPYEDDFTLIGTTDQDYDGEPRDAAISPAETDYLCAAASEYFARPVRREDIVWTYA
AVRPLFDDGASKAQEATRDYVLRVEEGDGDAALVNIFGGKITTYRRLSEATLEKIEELLGRKGQAWTADARLPGGDFAVD
GFDGQIAGLLRDYPFLNAGHARRLVRRYGTRARAILGQARSTDDLGVHFGADLYEAEVRYLMEQEWARTAEDVLWRRTKR
GLRLAPNEVVTLEEFMEDLASRRRHEAAE

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=516, Percent_Identity=32.5581395348837, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI285002231, Length=516, Percent_Identity=32.5581395348837, Blast_Score=183, Evalue=4e-46,
Organism=Escherichia coli, GI2367226, Length=474, Percent_Identity=47.8902953586498, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1788574, Length=478, Percent_Identity=28.4518828451883, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17509253, Length=526, Percent_Identity=31.5589353612167, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI115534726, Length=511, Percent_Identity=29.3542074363992, Blast_Score=154, Evalue=8e-38,
Organism=Saccharomyces cerevisiae, GI6322036, Length=524, Percent_Identity=29.1984732824427, Blast_Score=170, Evalue=6e-43,
Organism=Drosophila melanogaster, GI161077125, Length=513, Percent_Identity=30.9941520467836, Blast_Score=165, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24653942, Length=513, Percent_Identity=30.9941520467836, Blast_Score=165, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24653944, Length=513, Percent_Identity=30.9941520467836, Blast_Score=165, Evalue=8e-41,
Organism=Drosophila melanogaster, GI20130025, Length=513, Percent_Identity=30.9941520467836, Blast_Score=165, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24586295, Length=531, Percent_Identity=29.5668549905838, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI19921278, Length=493, Percent_Identity=24.1379310344828, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 57065; Mature: 57065

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGTPVHDILVIGGGINGCGIARDAAGRGYSVFLAEMNDLGSGTSSGSTKLIHGGLRYLE
CCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEEHHCCCCCCCCCCCEEEHHHHHHHH
FYEFRLVREALLEREVLWRNAPHIIWPMRFVLPHNEGLRPAWLLRLGLFLYDHLGGRKLL
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCC
PKTRTIDMRIDAAGKPLKPLFSRAFEYSDCWVDDARLVVLNARDAADRGAVIATRTEVVD
CCCEEEEEEECCCCCCHHHHHHHHCCCCCCEECCCEEEEEECCCCCCCCCEEEEHHHHHH
ARREDGRWRATLRDVSSGARSEVRARLVVNAAGPWVDKVLASAMGRNEVHNVRLVKGSHI
HHHCCCCEEHHHHHHHCCHHHHEEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEEECCEE
VVPKVSDDPRAYFFQNRDGRIIFAIPYEDDFTLIGTTDQDYDGEPRDAAISPAETDYLCA
EEECCCCCCCEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHH
AASEYFARPVRREDIVWTYAAVRPLFDDGASKAQEATRDYVLRVEEGDGDAALVNIFGGK
HHHHHHHCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHEEEEEEECCCCCEEEEEECCCC
ITTYRRLSEATLEKIEELLGRKGQAWTADARLPGGDFAVDGFDGQIAGLLRDYPFLNAGH
CHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEECCCCHHHHHHHCCCCCCCHH
ARRLVRRYGTRARAILGQARSTDDLGVHFGADLYEAEVRYLMEQEWARTAEDVLWRRTKR
HHHHHHHHCCHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLRLAPNEVVTLEEFMEDLASRRRHEAAE
CCEECCCCEEEHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDGTPVHDILVIGGGINGCGIARDAAGRGYSVFLAEMNDLGSGTSSGSTKLIHGGLRYLE
CCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEEHHCCCCCCCCCCCEEEHHHHHHHH
FYEFRLVREALLEREVLWRNAPHIIWPMRFVLPHNEGLRPAWLLRLGLFLYDHLGGRKLL
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCC
PKTRTIDMRIDAAGKPLKPLFSRAFEYSDCWVDDARLVVLNARDAADRGAVIATRTEVVD
CCCEEEEEEECCCCCCHHHHHHHHCCCCCCEECCCEEEEEECCCCCCCCCEEEEHHHHHH
ARREDGRWRATLRDVSSGARSEVRARLVVNAAGPWVDKVLASAMGRNEVHNVRLVKGSHI
HHHCCCCEEHHHHHHHCCHHHHEEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEEECCEE
VVPKVSDDPRAYFFQNRDGRIIFAIPYEDDFTLIGTTDQDYDGEPRDAAISPAETDYLCA
EEECCCCCCCEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHH
AASEYFARPVRREDIVWTYAAVRPLFDDGASKAQEATRDYVLRVEEGDGDAALVNIFGGK
HHHHHHHCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHEEEEEEECCCCCEEEEEECCCC
ITTYRRLSEATLEKIEELLGRKGQAWTADARLPGGDFAVDGFDGQIAGLLRDYPFLNAGH
CHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEECCCCHHHHHHHCCCCCCCHH
ARRLVRRYGTRARAILGQARSTDDLGVHFGADLYEAEVRYLMEQEWARTAEDVLWRRTKR
HHHHHHHHCCHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLRLAPNEVVTLEEFMEDLASRRRHEAAE
CCEECCCCEEEHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]